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Of Mice And Medicine: An Examination Of The Anti-Depressant Enterprise, James Kenneth Arnette
Of Mice And Medicine: An Examination Of The Anti-Depressant Enterprise, James Kenneth Arnette
Electronic Theses and Dissertations
Anti-depressants (ADs) appear not to work very well, and present a sequence of puzzling problems: side effects, a long latency period before recovery, an uncertain theoretical foundation for psychopharmacology, the high relative efficacy of placebos, and the generally low efficacy of ADs. Behind these empirical and scientific problems lie a host of ethical issues within drug development: publication bias, conflicts of interest, ghost authorship, and informed consent. I review these issues and find that: (1) there is no reason why ADs should be effective for humans, given their origin in rodent research; (2) the placebo effect rivals the drug effect, …
Depression In Young Adult Women Following Childhood Maltreatment: The Role Of Attitudes And Perceptions About Social Support, Thomas Dodson
Depression In Young Adult Women Following Childhood Maltreatment: The Role Of Attitudes And Perceptions About Social Support, Thomas Dodson
Electronic Theses and Dissertations
Introduction: A history of childhood maltreatment has been related to mental health concerns inadulthood, with depression showing the largest amount of empirical support. Perceptions of social support have been shown to have a protective effect (buffer against mental health symptoms particularly for survivors of more severe maltreatment) and a promotive effect (direct positive effect on mental health symptoms regardless of the severity of child maltreatment) with mental health concerns. Research has shown more consistent support for the promotive effect of social support on mental health outcomes in adults who have a history of childhood maltreatment. The protective effect of social …