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Examining The Effects Of Social Isolation On Nicotine Preference And Mesolimbic Dopamine, Nicholas Bross Paige
Examining The Effects Of Social Isolation On Nicotine Preference And Mesolimbic Dopamine, Nicholas Bross Paige
Electronic Theses and Dissertations
Factors relating to social interaction have been shown to alter patterns of psychostimulant use in preclinical and clinical models. The present study aimed to determine the effects of social isolation on nicotine preference using conditioned place preference (CPP) and the effects social isolation and nicotine exposure on reward-related dopamine release in the nucleus accumbens (NAc). Regarding CPP results, there was a significant housing (group or isolated) x drug (nicotine or saline) x trial interaction on time spent in the drug-paired chamber. Regarding dopamine recordings, there was a significant housing x drug exposure (nicotine or saline) x time (60 min recording …
Characterization Of Ti-6al-4v Cellular Structures For Bone Scaffolds Application, Muhammad Abdus Salam
Characterization Of Ti-6al-4v Cellular Structures For Bone Scaffolds Application, Muhammad Abdus Salam
Electronic Theses and Dissertations
Additively manufactured Ti-6Al-4V cellular structures are the most popular metallic choices for bonetissue engineering (BTE) applications. In this work, laser-based powder bed fusion (PBF) technologywas employed to fabricate Ti-6Al-4V cellular structures with geometries mimicking human cancellousbone properties. This study introduces novel laser scanning strategies with their associated laserbased PBF processing parameters for the fabrication of fine resolution Ti-6Al-4V cellular structureswith tailored mechanical properties to improve their mechanical performance. Two distinct designedgeometries, diamond and dodecahedron, in four different pore sizes were manufactured byemploying three different laser-based PBF scanning strategies in combination with various laserpower and scanning speeds while the laser spot …
An Efficient Approach To Screening Mediators In Epigenetic Data: Emscreening, Alexandra Nicole Smith
An Efficient Approach To Screening Mediators In Epigenetic Data: Emscreening, Alexandra Nicole Smith
Electronic Theses and Dissertations
Mediation analyses study the effect of exposures on outcomes thorugh mediators. With the develoment of high throughput technologies, high-dimenisonal data are increasinbl produced. To better control fro both Type I and II errors in high dimensional data, a screening method, emscreening, was developed using cross-validation. Through simulation studies, we examined the sensitivity and specificity of emscreening in different scenarios and compared them to two commonly used methods: the false-discovery rate (FDR) and Bonferroni methods. The propsed method showed higher sensitivity and comparable specificyt with the number of mediators tested was large (5,000 or 500,000). Overall, emscreening can identify significant mediators …
Secure Sharing Of Spatio-Temporal Data Through Name-Based Access Control, Laqin Fan
Secure Sharing Of Spatio-Temporal Data Through Name-Based Access Control, Laqin Fan
Electronic Theses and Dissertations
Named Data Networking (NDN) is proposed as a future Internet architecture, which provides name-based data publishing and fetching primitive. Compared to TCP/IP, the benefits of NDN are as follows. NDN removes the need to manage IP address; NDN provides semantically meaningful and structured names; NDN has a stateful and name-based forwarding plane; NDN supports data-centric security and in-network caching. Name-based Access Control is an access control solution proposed over NDN, which is a content-based access control by encrypting data at the time of production directly without relying on a third-party service(i.e., Cloud storage), utilizes NDN’s hierarchical naming convention to express …
Ndnsd: Service Publishing And Discovery In Ndn, Saurab Dulal
Ndnsd: Service Publishing And Discovery In Ndn, Saurab Dulal
Electronic Theses and Dissertations
Service discovery is one of the crucial components of modern applications. With the advent of several new systems such as IoT, edge, cloud, etc the world is connected more than ever and smart devices are creeping towards every nook and corner of our surroundings. Not only the new systems are emerging but also the communication pattern is evolving i.e. from one-to-one (host-host) to many-to-many (distributed application, IoT). The definition of service has also changed over time. Unlike their meaning in the past as programs running on some machines, services today can be sensor devices collecting data, mobile devices offering computing …
Electrosprayed Chitosan-Calcium Phosphate Nanoshells Composite Coatings On Silanated Titanium Plates, Andrew Blass Watson
Electrosprayed Chitosan-Calcium Phosphate Nanoshells Composite Coatings On Silanated Titanium Plates, Andrew Blass Watson
Electronic Theses and Dissertations
The aim of this work was to take advantage of the electrospray technology and the osteocompatibility of both chitosan and calcium phosphate (CaP) to fabricate chitosan coatings loaded with CaP nanoshell particles. The key electrospray parameters of capillary diameter, voltage, and pressure were identified and adjusted for creating uniform chitosan-CaP coatings on titanium surfaces. Coatings containing from 0 to 1 wt% CaP particles to chitosan mass were electrosprayed on to silanated titanium to create composite coatings bonded to the metal surface. Scanning electron microscope (SEM) and energy dispersive X-ray spectroscopy (EDS) showed that CaP particles were homogenously distributed throughout the …
Investigating Late Paleozoic Tectonic Deformation Of The Western Highland Rim, Tennessee, Tyler John Myrman
Investigating Late Paleozoic Tectonic Deformation Of The Western Highland Rim, Tennessee, Tyler John Myrman
Electronic Theses and Dissertations
The Western Highland Rim (WHR) of Tennessee is located between the Nashville Dome to the east and the Mississippi Embayment to the west. This region is situated inside the bend of the Appalachian-Ouachita orogen along the eastern margin of the Laurentian craton, making it a location of intrigue for structural analysis. Far-field and local stresses have deformed the WHR across multiple Eras. In the Paleozoic, the Appalachian (east of WHR) and Ouachita (south of WHR) orogenies were both thrusting onto the Laurentian craton. Mesoscale structures recorded in the WHR indicate shortening direction history of these tectonic stresses, how many pulses …
On The Arrangement Of Visual Features For Efficient And Accurate Prediction Using A Linear Model, Monika Shah
On The Arrangement Of Visual Features For Efficient And Accurate Prediction Using A Linear Model, Monika Shah
Electronic Theses and Dissertations
Assuming the brain is a prediction machine, we investigate the arrangement of 2D visual features (Gabor filters) such that visual prediction can be carried out efficiently. The contributions of this thesis are threefold: (1) we prove that a 1-mode tensor can be predicted from an n-mode and an (n-1)-mode tensors; (2) using a linear model to predict visual features at varying distances from a given location, we show that prediction error increases smoothly and monotonically with increase in distance and increase in degree of sparsity of the prediction model; (3) we show that the visual features can be arranged in …
Decoding Perception Of Speech From Behavioral Responses Using Spatio-Temporal Cnns, Kazi Ashraf Moinuddin
Decoding Perception Of Speech From Behavioral Responses Using Spatio-Temporal Cnns, Kazi Ashraf Moinuddin
Electronic Theses and Dissertations
Categorical perception (CP) of speech is a complex process reflecting individuals’ ability to perceive sound and is measured using response time (RT). The cognitive processes involved in mapping neural activities to behavioral response are stochastic and further compounded by individuality and variations. This thesis presents a data-driven approach and develops parameter optimized models to understand the relationship between cognitive events and behavioral response (e.g., RT). We introduce convolutional neural networks (CNN) to learn the representation from EEG recordings. In addition, we develop parameter optimized and interpretable models in decoding CP using two representations: 1) spatial-spectral topomaps and 2) evoked response …
Reducing Tornado Warning False Alarm Rates Across The National Weather Service Memphis County Warning Area, Preston Jewel Bradley
Reducing Tornado Warning False Alarm Rates Across The National Weather Service Memphis County Warning Area, Preston Jewel Bradley
Electronic Theses and Dissertations
Tornado detection has improved in recent years due, in part, to the deployment of dual-polarization radar technology. Depsite these improvements, false alarm rates (FAR) for tornado warnings remain high over Memphis, TN County Warning Area. The purpose of this research was to use a suite of radar products and storm environmental parameters in an effort to decrease tornado warning FAR over the Mid-South. The Memphis National Weather Service Forecast Office County Warning Area (CWA) serves as the study area for this reseach. Previous research has shown that storm mode and environment can imact FAR. Therefore, by combining radar products and …
Context Matters: Attitudes And Perceptions Of Proposed Bike Lanes In Memphis, Tn, David A. Hudlow
Context Matters: Attitudes And Perceptions Of Proposed Bike Lanes In Memphis, Tn, David A. Hudlow
Electronic Theses and Dissertations
This research leverages a City of Memphis dataset of over 1,700 survey responses with over 2,400 comments for understanding how people make decisions regarding support for or opposition to bike lanes in their communities. The survey comments were analyzed using both descriptive and thematic analyses along with unbiased computer-generated topic models. Six primary themes were identified along with six major intersections of these themes that provided important insights for understanding respondents’ perspectives. The primary themes are: People on bikes deserve a space on the road, Danger and safety, Roadway is for cars and drivers, No real need for bike lanes, …
Berth Allocation At Passenger Terminals: A Bundle Auction Approach, Dimitrios Konstantinos Giampouranis
Berth Allocation At Passenger Terminals: A Bundle Auction Approach, Dimitrios Konstantinos Giampouranis
Electronic Theses and Dissertations
In this thesis we present a multi-round second price sealed-bid auction for the berth slot leasing for vessels (RoPax and/or cruise ships) at a public marine terminal. The auction mechanism is designed to maximize the port operator's profits by auctionng berth (time)slots in groups. The framework is being tested using simulation by varying the number of RoPax/cruise ship operating companies; the number o slots they bid for; and the mechanism design with regards to the winner determination, slot valuation, and max to min slot bid ration among the bidders. Results are compared to a single item multi-round second price auction …
Mapping Of Velocity Variations To Investigate Seismicity In The Upper Crust Of The Central Virginia Seismic Zone, Virginia, Usa, S M Ariful Islam
Mapping Of Velocity Variations To Investigate Seismicity In The Upper Crust Of The Central Virginia Seismic Zone, Virginia, Usa, S M Ariful Islam
Electronic Theses and Dissertations
Local earthquake tomography is used to investigate three dimensional velocity structure in the aftershock zone of the 2011 Mineral, VA, mainshock. A total of 5125 arrival times for 324 aftershocks recorded by 12 stations were used in the inversion. The inversion volume is small (22 x 20 x 16 km) with a block size of 1 x 1 x 1 km. Most of the aftershocks located at or below 2 km are associated with an NE trending, SE dipping anomalous velocity region with negative P-wave velocity (Vp) anomalies, positive S-wave velocity (Vs) anomalies, and Vp/Vs ratios as low as 1.54. …
Epigenome-Wide Association Of Infant Feeding And Changes In Dna Methylation From Birth To 10 Years, Yamini Mallisetty
Epigenome-Wide Association Of Infant Feeding And Changes In Dna Methylation From Birth To 10 Years, Yamini Mallisetty
Electronic Theses and Dissertations
Epigenetic markers have been suggested as mediators of early-life nutrition to future health. Prior studies focused on breastfeeding effects on DNA methylation (DNAm), ignoring other feeding modes. In this analysis of the Isle of Wight birth cohort, feeding modes were categorized as exclusive breastfeeding (EBF), exclusive formula feeding (EFF), and mixed feeding based on whether the respective feeding mode lasted for at least 3 months. In addition, in the past, infant feeding modes were assessed using one time point DNAm in childhood, not changes of DNAm. In this paper, methylation differences (Delta DNAm) were calculated by subtracting residual methylation values …
Geologic Mapping Of Dyer County, Tennessee, Renee Marie Reichenbacher
Geologic Mapping Of Dyer County, Tennessee, Renee Marie Reichenbacher
Electronic Theses and Dissertations
The stratigraphy and structure beneath Dyer County, Tennessee, were mapped using lignite exploration wells, water wells, US Army Corps of Engineers borings, and previously interpreted seismic reflection lines to better understand the seismic threat of the underlying New Madrid seismic zone structures. New Madrid seismic zone earthquakes are concentrated on faults of the Reelfoot rift, one system of which is the northwest-trending Lake County uplift and Tiptonville dome, which extends in northwestern Tennessee through Lake and Obion counties into Dyer County. Structure contour maps of the tops of the Paleozoic, Cretaceous, and Eocene sections were made to produce cross-sections and …
The Impact Of Diet And Fasting Protocols On Intestinal Architecture And Immune Parameters, Raed Yahya I Ageeli M.S.
The Impact Of Diet And Fasting Protocols On Intestinal Architecture And Immune Parameters, Raed Yahya I Ageeli M.S.
Electronic Theses and Dissertations
High fiber/plant-based diet and fasting and timed feeding protocols under a high-fat diet change the gut microbiota, the histological structure, and the immune parameters of the intestine. The purpose of this study was to assess the influence of different dietary interventions, including a high-fiber/plant-based or a high-fat diet, and several time-restricted feeding protocols, on the intestinal crypt and villus morphology, the number of intestinal goblet cells (GC), and the changes in inflammatory parameters. Healthy C57BL/6 male mice were fed a high fat (HF) diet for 6 weeks, and then randomly divided to follow 1) continual-ad libitum high-fat diet (HFD), 2) …
Hope Home For Children: How Architecture Can Heal People Emotionally, Fatemeh Sahamirad
Hope Home For Children: How Architecture Can Heal People Emotionally, Fatemeh Sahamirad
Electronic Theses and Dissertations
This thesis investigates how architecture can heal people by creating spaces that consider emotional needs. This exploration is developed through the design of a group home for children without parental support in Memphis, Tennessee. This thesis suggests that the solution to the problem of a place for children is not just providing shelter. Rather, the challenge is to create spaces that respond to their psychosocial needs in different stages of life. This design engages human psychology and particular human interaction in the community (in large and small groups) as well as providing spaces for individual expression.
Study Of Groundwater-Surface Water Interactions To Identify Potential Aquitard Breach Locations Along The Wolf River, Tennessee, Sagar Pandit
Electronic Theses and Dissertations
Inter-aquifer exchanges due to breaches in the confining clay layer can potentially contaminate the Memphis aquifer, as lesser-quality waters permeate from the unconfined aquifer. Losing river reaches could indicate breach locations, as these should depress water-table locally, resulting in downward vertical exchange fluxes (VEFs) along nearby streambeds. A spatial analysis of seepage meter measurements performed along the Wolf River identified three potentially losing sub-reaches, where VEFs were studied at a finer scale, using multiple point-scale methods. Results were mixed, displaying large spatial variability, possibly due to mismatches between the process and observation scales. Differential stream gaging was conducted to assess …
Reduced-Order Model Predictions Of Wind Turbines Via Mode Decomposition And Sparse Sampling, Ala' Eyad Qatramez
Reduced-Order Model Predictions Of Wind Turbines Via Mode Decomposition And Sparse Sampling, Ala' Eyad Qatramez
Electronic Theses and Dissertations
Wind turbine wakes are dominated by several energetic turbulent coherent structures that oscillate at specific Strouhal numbers. Implications on wind power harvesting of these dynamic, induced features require accurate unsteady modeling. Dynamic mode decomposition (DMD), a data-driven modal analysis, has demonstrated the ability to identify flow features based on specific frequencies. In this work, the selection of modes and data-driven DMD models pertaining to wakes with constant Strouhal number coherent structures are investigated using physically-informed criteria and sparse sampling. Both criteria are validated with a low Reynolds number flow behind a square cylinder. Next, the techniques are applied to data …
Rainfall Sampling Adjustment Factors: Spatial Variability And Effects Of Temporal Resolution Of Precipitation, Apeksha Marasini
Rainfall Sampling Adjustment Factors: Spatial Variability And Effects Of Temporal Resolution Of Precipitation, Apeksha Marasini
Electronic Theses and Dissertations
Rainfall maxima over short durations are of great importance when designing stormwater drainage structures in smaller watersheds. Typically, design storms are extracted from rainfall Depth-Duration-Frequency curves developed from continuously gaged rainfall data collected over fixed (clock) time intervals. This can negatively bias our estimates of the true rainfall maxima when the gage collection interval is close to the duration of interest. Sampling Adjustment Factors (SAFs) have been used to rectify this error, but most studies have been limited to low-resolution data, and very few have focused on spatial variability. We use concurrent high resolution (1-minute) rainfall data from 809 stations …
Hydrogeologic Investigation Of Subsurface Stratigraphy Using Ground Penetrating Radar In Southwestern Shelby County, Tennessee, Md Rizwanul Hasan
Hydrogeologic Investigation Of Subsurface Stratigraphy Using Ground Penetrating Radar In Southwestern Shelby County, Tennessee, Md Rizwanul Hasan
Electronic Theses and Dissertations
This study used ground penetrating radar (GPR) with 160 MHz and 50 MHz antennae to image up to 30 m of the subsurface in the southwestern Shelby to investigate the upper Claiborne confining unit (UCCU) underlying the Mississippi River Valley Alluvial (MRVA) aquifer. Interpretations with limited ground-truthing from nearby well logs show that the GPR frequencies used could penetrate deep enough but lost resolution due to signal attenuation in saturated, fine sediments. Interpreted data shows shallow subsurface stratigraphy and deformation in the area. Faults and fractures are evident in radargrams from Horn Lake cut-off (HLC) and Ensley Bottoms Pump Station …
Reliability Of Graph Measures Derived From Resting-State Meg Data Using Source Space Functional Connectivity Analysis, Haatef Pourmotabbed
Reliability Of Graph Measures Derived From Resting-State Meg Data Using Source Space Functional Connectivity Analysis, Haatef Pourmotabbed
Electronic Theses and Dissertations
The reliability of global graph measures derived from neuroimaging data is an important criterion for their use as biomarkers for neurological disorders. This study examined the reliability of the global efficiency (GE), characteristic path length (CPL), transitivity, and synchronizability of functional whole-brain and intra-hemispheric networks based on resting-state magnetoencephalography. Brain sources were reconstructed using atlas-based beamforming, and functional connectivity in six frequency bands was estimated using the debiased weighted phase lag index. An optimal threshold of 100% was chosen based on test-retest reliability of the measures. At this threshold, test-retest reliability of the GE, CPL, and transitivity was mostly fair …
Quantitative Analysis And Monte Carlo Modeling Of Fat-Mediated Mri Relaxation, Utsav Shrestha
Quantitative Analysis And Monte Carlo Modeling Of Fat-Mediated Mri Relaxation, Utsav Shrestha
Electronic Theses and Dissertations
Hepatic steatosis is the accumulation of fat in the liver, affecting about 25% of the world population. Steatosis can cause lipo-toxicity and eventually lead to fibrosis, cirrhosis and ultimately liver failure if timely interventions are not provided. So, early diagnosis and disease monitoring of steatosis is crucial to reduce morbidity and mortality.Chemical shift based Magnetic Resonance Imaging (MRI) techniques using single and dual R2*(transverse relaxation rate) models have been reported to quantify fat fraction (FF) for assessment of steatosis. However, there is no common consensus between these two models and current data is limited for which model is accurate to …
Perceived Social Norms In Relation To Internet Gaming And Problems Among College Students, Qian Li
Perceived Social Norms In Relation To Internet Gaming And Problems Among College Students, Qian Li
Electronic Theses and Dissertations
To better understand college student’s gaming behavior, the present study used an online survey to investigate how college students’ Internet gaming and problems relate to the perceived descriptive and perceived injunctive social norms they hold. It was hypothesized that college students would report higher perceived descriptive norms for Internet gaming frequency and expenditure than their own self-reported behaviors. It was also hypothesized that both perceived descriptive norms and perceived injunctive norms would have a positive relation with Internet gaming frequency and problems. These hypotheses were partially supported. College students reported higher perceived descriptive norms for Internet gaming frequency and expenditure …
A Multimedia Approach To Improving Retention In Undergraduate Anatomy And Physiology, Kaitlyn Elizabeth Peperone
A Multimedia Approach To Improving Retention In Undergraduate Anatomy And Physiology, Kaitlyn Elizabeth Peperone
Electronic Theses and Dissertations
This research compared differences in grades among students who utilized an adaptive instructional system (AIS) to study for their undergraduate anatomy and physiology exams. The AIS implemented multimedia techniques by combining machine-generated cloze questions with images drawn from the A&P textbook, specifically chapters 9 (musculature) and 10 (nervous system). The AIS adapted to the performance of each student and optimally chose which question they should see next. Participants studied using this AIS before the exam and were given extra credit for participation. I hypothesized that students who practiced using the AIS will perform better on their exams than those that …
If You Want The Milk, Buy The Cow: A Study Of Young Black Women's Experiences In Situationships, Tierica Jemise Gibson
If You Want The Milk, Buy The Cow: A Study Of Young Black Women's Experiences In Situationships, Tierica Jemise Gibson
Electronic Theses and Dissertations
Research on casual dating relationships remain centered on white individuals, particularly white women. Social dating research has largely ignored the lived experiences of women of color, particularly black women, and continues its commitment to studying participation and experiences in casual dating relationships through a white lens. Situationships can be described as noncommittal dating relationships which teeter between committed relationships and casual dating. Semi- structures interviews were conducted to collect data on black women’s experiences in situationships in order to provide greater understanding of how both race and gender shape black women’s dating experiences. This study found that situationships operate within …
Racial Differences In Life Expectancy Among Shelby County, Tennessee Residents, Sarah Ashley Nicole Collins
Racial Differences In Life Expectancy Among Shelby County, Tennessee Residents, Sarah Ashley Nicole Collins
Electronic Theses and Dissertations
Life expectancy is a key measure in population health. Although there have been significant gains in the past decades, deep disparities still persist along racial lines. The aim of this paper is to analyze the disparate life chances of racial and ethnic minorities within Shelby County, Tennessee. OLS regression is used to investigate the association between life expectancy and various sociodemographic variables. The overall life expectancy of Shelby County is years below the national average, and the results of this project find that there are stark differences across census tracts.
Analysis Of Tennessee's Statewide Residential Surveys: Past Trends And Future Directions, David Kwadwo Oppong
Analysis Of Tennessee's Statewide Residential Surveys: Past Trends And Future Directions, David Kwadwo Oppong
Electronic Theses and Dissertations
In order to determine customer satisfaction among residents, the Tennessee Department of Transportation (TDOT) conducted three surveys over a ten-year period. The aims of this thesis reserach were to identify and visualize trends over time and to develop a framework to improve the practices utilized by TDOT in future feedback surveys to inform strategic planning. An analysis was performed to investigate the change in trends over time for four demographic categories--urban and rural, economic status, TDOT regions and TDOT super districts. Trends that satisfied practical and statistical significance were visualized in ArcGIS to better communicate results with residents and stakeholders. …
Ultrasonic Vocalizations As A Potential Indicator Of A Negative Affective State In Forelimb-Amputated Rats, Carey Daniel Womack
Ultrasonic Vocalizations As A Potential Indicator Of A Negative Affective State In Forelimb-Amputated Rats, Carey Daniel Womack
Electronic Theses and Dissertations
Most amputees experience phantom limb pain (PLP) post-amputation, the mechanisms of which are not fully understood. Rat amputees may serve as a practical model for studying PLP, as rats process pain similarly to primates. Ultrasonic vocalizations (USVs) of acclimated, formalin-injected rats and acclimated, forelimb-amputated rats were recorded to investigate the potential for measuring USVs as an indicator of a negative affective state. Subcutaneous injections of 10% formalin in the hindpaw elicited increased USV emission, primarily in the 22 kHz-AFR. Unoperated rats and forelimb-amputated rats were monitored for seven weeks following acclimation and surgery. Amputees emitted a greater quantity of 22 …
Ring Polymers As A Model For Cellular Organization, Yu Zhu
Ring Polymers As A Model For Cellular Organization, Yu Zhu
Electronic Theses and Dissertations
A number of experimental studies have been reported on the spatial organization and collective motion of living cells during the past few decades. To explain the experimentally observed results, we propose a novel approach, in which the cells are modeled as semi-flexible ring polymers. We found that the basic physical properties of the polymer rings, such as average area per cell, elongation, and orientation highly depend on the areal polymer density. Investigations of systems composed of two types of ring polymers with different bending rigidities show that multi-component ring-polymer systems exhibit microphase separation. Simulations of the ring polymers on a …