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University of Arkansas, Fayetteville

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Mole Street Journal, January 2020, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Jan 2020

Mole Street Journal, January 2020, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, June 2019, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Jun 2019

Mole Street Journal, June 2019, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, April 2019, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Apr 2019

Mole Street Journal, April 2019, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, February 2019, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Feb 2019

Mole Street Journal, February 2019, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, December 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Dec 2018

Mole Street Journal, December 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, October 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Oct 2018

Mole Street Journal, October 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, August 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Aug 2018

Mole Street Journal, August 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Conformationally-Controlled Late-Stage Modifications For Sar Studies Of The C-3-Glcp Moiety Of Ipomoeassin F, Lucas Whisenhunt Aug 2018

Conformationally-Controlled Late-Stage Modifications For Sar Studies Of The C-3-Glcp Moiety Of Ipomoeassin F, Lucas Whisenhunt

Graduate Theses and Dissertations

The resin glycoside, ipomoeassin F has been shown to be extremely potent against multiple cancer lines (IC50 = 4.2-36 nM). However, the mechanism of action of this potent and complex natural product is still not fully understood. The α,β-unsaturated esters of the glucosyl moiety have been shown to be vital for the overall cytotoxicity of ipomoeassin F. Nevertheless, the importance of the tigloyl ester of the glucosyl moiety is still largely unknown. This work aimed to study the pharmacophore importance of the tigloyl ester by creating, an efficient, scalable, and flexible synthesis route for various analogs. The 18-linear step synthesis …

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Mole Street Journal, June 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Jun 2018

Mole Street Journal, June 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, April 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Apr 2018

Mole Street Journal, April 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, February 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Feb 2018

Mole Street Journal, February 2018, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, December 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Dec 2017

Mole Street Journal, December 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, October 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Oct 2017

Mole Street Journal, October 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, August 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Aug 2017

Mole Street Journal, August 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, June 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Jun 2017

Mole Street Journal, June 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, April 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Apr 2017

Mole Street Journal, April 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, February 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Feb 2017

Mole Street Journal, February 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, December 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Dec 2016

Mole Street Journal, December 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, October 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Oct 2016

Mole Street Journal, October 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, August 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Aug 2016

Mole Street Journal, August 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, June 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Jun 2016

Mole Street Journal, June 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, April 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Apr 2016

Mole Street Journal, April 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, February 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Feb 2016

Mole Street Journal, February 2016, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, December 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Dec 2015

Mole Street Journal, December 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, October 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Oct 2015

Mole Street Journal, October 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, August 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Aug 2015

Mole Street Journal, August 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, June 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Jun 2015

Mole Street Journal, June 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Fluorescent Cell Imaging Studies Of Antitumor Natural Macrocycle Ipomoeassin F, Margaret Grace Oliver May 2015

Fluorescent Cell Imaging Studies Of Antitumor Natural Macrocycle Ipomoeassin F, Margaret Grace Oliver

Biological Sciences Undergraduate Honors Theses

Ipomoeassin F is one member of a family of macromolecules isolated from the leaves of the morning glory flower, ipomoea squamosa, which has been used as a homeopathic cancer remedy for centuries (Zhu, Huang, Zheng, Zhu, & Yang, 2013). It has been proven to be highly cytotoxic to many cancer cell lines, but nothing is yet known of its mode of action in the cell (Cao, et al., 2007). To begin progress towards understanding the mode of action of ipomeoassin F, this study aimed to perform fluorescence imaging studies for the ultimate purpose of determining its cellular localization in MDA-MB-231 …

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Mole Street Journal, April 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Apr 2015

Mole Street Journal, April 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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Mole Street Journal, February 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry Feb 2015

Mole Street Journal, February 2015, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

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