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Recombinant Expression And Purification Of Amyloid-Β In E. Coli, Wisam M. Beauti
Recombinant Expression And Purification Of Amyloid-Β In E. Coli, Wisam M. Beauti
Honors Theses
Alzheimer’s disease (AD) is a common neurodegenerative disorder that affects people older than 65 years 1,2,5. It is characterized by the presence of extracellular plaque deposits that are seen specifically in the brains of AD patients 4,5. These plaques are mainly comprised of amyloid-β (Aβ) peptide aggregates. Aβ plaque production and deposition is believed to drive AD pathogenesis. Studying these proteins is crucial to understanding aspects of AD in order to develop possible therapeutic treatments. Recombinant expression of Aβ can also provide a handle to introduce mutations in the protein to further study their structure-function relationships. However, synthetic Aβ monomer …
A Comparative Study Teaching Chemistry Using The 5e Learning Cycle And Traditional Teaching With A Large English Language Learner Population In A Middle School Setting, Cynthia Nicole Mcwright
A Comparative Study Teaching Chemistry Using The 5e Learning Cycle And Traditional Teaching With A Large English Language Learner Population In A Middle School Setting, Cynthia Nicole Mcwright
Dissertations
For decades science educators and educational institutions have been concerned with the status of science content being taught in K-12 schools and the delivery of the content. Thus, educational reformers in the United States continue to strive to solve the problem on how to best teach science for optimal success in learning. The constructivist movement has been at the forefront of this effort. With mandatory testing nationwide and an increase in science, technology, engineering, and mathematics (STEM) jobs with little workforce to fulfill these needs, the question of what to teach and how to teach science remains a concern among …