Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Louisiana State University

2008

Discipline
Keyword
Publication
Publication Type

Articles 1 - 30 of 1022

Full-Text Articles in Entire DC Network

Chromosomal Inversions Between Human And Chimpanzee Lineages Caused By Retrotransposons, Jungnam Lee, Kyudong Han, Thomas J. Meyer, Heui Soo Kim, Mark A. Batzer Dec 2008

Chromosomal Inversions Between Human And Chimpanzee Lineages Caused By Retrotransposons, Jungnam Lee, Kyudong Han, Thomas J. Meyer, Heui Soo Kim, Mark A. Batzer

Faculty Publications

The long interspersed element-1 (LINE-1 or L1) and Alu elements are the most abundant mobile elements comprising 21% and 11% of the human genome, respectively. Since the divergence of human and chimpanzee lineages, these elements have vigorously created chromosomal rearrangements causing genomic difference between humans and chimpanzees by either increasing or decreasing the size of genome. Here, we report an exotic mechanism, retrotransposon recombination-mediated inversion (RRMI), that usually does not alter the amount of genomic material present. Through the comparison of the human and chimpanzee draft genome sequences, we identified 252 inversions whose respective inversion junctions can clearly be characterized. …

Go to article

Structure Of A Complete Integrin Ectodomain In A Physiologic Resting State And Activation And Deactivation By Applied Forces, Jianghai Zhu, Bing Hao Luo, Tsan Xiao, Chengzhong Zhang, Noritaka Nishida, Timothy A. Springer Dec 2008

Structure Of A Complete Integrin Ectodomain In A Physiologic Resting State And Activation And Deactivation By Applied Forces, Jianghai Zhu, Bing Hao Luo, Tsan Xiao, Chengzhong Zhang, Noritaka Nishida, Timothy A. Springer

Faculty Publications

The complete ectodomain of integrin αIIbβ3 reveals a bent, closed, low-affinity conformation, the β knee, and a mechanism for linking cytoskeleton attachment to high affinity for ligand. Ca and Mg ions in the recognition site, including the synergistic metal ion binding site (SyMBS), are loaded prior to ligand binding. Electrophilicity of the ligand-binding Mg ion is increased in the open conformation. The β3 knee passes between the β3-PSI and αIIb-knob to bury the lower β leg in a cleft, from which it is released for extension. Different integrin molecules in crystals and EM reveal breathing that appears on pathway to …

Go to article

Design, Synthesis, And Structure - Activity Relationship, Molecular Modeling, And Nmr Studies Of A Series Of Phenyl Alkyl Ketones As Highly Potent And Selective Phosphodiesterase-4 Inhibitors, Shilong Zheng, Gurpreet Kaur, Huanchen Wang, Minyong Li, Megan Macnaughtan, Xiaochuan Yang, Suazette Reid, James Prestegard, Binghe Wang, Hengming Ke Dec 2008

Design, Synthesis, And Structure - Activity Relationship, Molecular Modeling, And Nmr Studies Of A Series Of Phenyl Alkyl Ketones As Highly Potent And Selective Phosphodiesterase-4 Inhibitors, Shilong Zheng, Gurpreet Kaur, Huanchen Wang, Minyong Li, Megan Macnaughtan, Xiaochuan Yang, Suazette Reid, James Prestegard, Binghe Wang, Hengming Ke

Faculty Publications

Phosphodiesterase 4 catalyzes the hydrolysis of cyclic AMP and is a target for the development of anti-inflammatory agents. We have designed and synthesized a series of phenyl alkyl ketones as PDE4 inhibitors. Among them, 13 compounds were identified as having submicromolar IC50 values. The most potent compounds have IC50 values of in the mid- to low-nanomolar range. Compound 5v also showed preference for PDE4 with selectivity of >2000-fold over PDE7, PDE9, PDE2, and PDE5. Docking of 5v, 5zf, and 5za into the binding pocket of the PDE4 catalytic domain revealed a similar binding profile to PDE4 with rolipram except that …

Go to article

Measurement Of The Single-Top-Quark Production Cross Section At Cdf, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzurri, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, V. Bartsch, G. Bauer, P. H. Beauchemin, F. Bedeschi, P. Bednar Dec 2008

Measurement Of The Single-Top-Quark Production Cross Section At Cdf, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzurri, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, V. Bartsch, G. Bauer, P. H. Beauchemin, F. Bedeschi, P. Bednar

Faculty Publications

We report a measurement of the single-top-quark production cross section in 2.2fb-1 of pp̄ collision data collected by the Collider Detector at Fermilab at s=1.96TeV. Candidate events are classified as signal-like by three parallel analyses which use likelihood, matrix element, and neural network discriminants. These results are combined in order to improve the sensitivity. We observe a signal consistent with the standard model prediction, but inconsistent with the background-only model by 3.7 standard deviations with a median expected sensitivity of 4.9 standard deviations. We measure a cross section of 2.2-0.6+0.7(stat+syst)pb, extract the Cabibbo-Kobayashi-Maskawa matrix-element value |Vtb|=0.88-0.12+0.13(stat+syst)±0.07(theory), and set the limit …

Go to article

Search For The Higgs Boson Produced In Association With Z→ℓ+ℓ- In Pp̄ Collisions At S=1.96tev, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzurri, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, V. Bartsch, G. Bauer, P. H. Beauchemin, F. Bedeschi, P. Bednar Dec 2008

Search For The Higgs Boson Produced In Association With Z→ℓ+ℓ- In Pp̄ Collisions At S=1.96tev, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzurri, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, V. Bartsch, G. Bauer, P. H. Beauchemin, F. Bedeschi, P. Bednar

Faculty Publications

We present a search for the Higgs boson in the process qq̄→ ZH→ℓ+ℓ-bb̄. The analysis uses an integrated luminosity of 1fb-1 of pp̄ collisions produced at s=1.96TeV and accumulated by the upgraded Collider Detector at Fermilab (CDF II). We employ artificial neural networks both to correct jets mismeasured in the calorimeter and to distinguish the signal kinematic distributions from those of the background. We see no evidence for Higgs boson production, and set 95% C.L. upper limits on σZHB(H→bb̄), ranging from 1.5 to 1.2 pb for a Higgs boson mass (mH) of 110 to 150GeV/c2. © 2008 The American Physical …

Go to article

Search For Supersymmetry In Pp Collisions At S=1.96tev Using The Trilepton Signature For Chargino-Neutralino Production, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzurri, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, V. Bartsch, G. Bauer, P. H. Beauchemin, F. Bedeschi, P. Bednar Dec 2008

Search For Supersymmetry In Pp Collisions At S=1.96tev Using The Trilepton Signature For Chargino-Neutralino Production, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzurri, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, V. Bartsch, G. Bauer, P. H. Beauchemin, F. Bedeschi, P. Bednar

Faculty Publications

We use the three lepton and missing energy trilepton signature to search for chargino-neutralino production with 2.0fb-1 of integrated luminosity collected by the CDF II experiment at the Tevatron pp collider. We expect an excess of approximately 11 supersymmetric events for a choice of parameters of the mSUGRA model, but our observation of 7 events is consistent with the standard model expectation of 6.4 events. We constrain the mSUGRA model of supersymmetry and rule out chargino masses up to 145GeV/c2 for a specific choice of parameters. © 2008 The American Physical Society.

Go to article

Effect Of Linker Structure On Surface Density Of Aptamer Monolayers And Their Corresponding Protein Binding Efficiency, Subramanian Balamurugan, Anne Obubuafo, Robin L. Mccarley, Steven A. Soper, David A. Spivak Dec 2008

Effect Of Linker Structure On Surface Density Of Aptamer Monolayers And Their Corresponding Protein Binding Efficiency, Subramanian Balamurugan, Anne Obubuafo, Robin L. Mccarley, Steven A. Soper, David A. Spivak

Faculty Publications

A systematic study is reported on the effect of linker size and its chemical composition toward ligand binding to a surface-immobilized aptamer, measured using surface plasmon resonance. The results, using thrombin as the model system, showed that as the number of thymidine (T) units in the linker increases from 0 to 20 in four separate increments (T0, T 5, T10, T20), the surface density of the aptamer decreased linearly from approximately 25 to 12 pmol·cm -2. The decrease in aptamer surface density occurred due to the increased size of the linker molecules. In addition, thrombin binding capacity was shown to …

Go to article

Two Evolutionarily Conserved Sequence Elements For Peg3/Usp29 Transcription, Jeong Do Kim, Sungryul Yu, Jung Ha Choo, Joomyeong Kim Dec 2008

Two Evolutionarily Conserved Sequence Elements For Peg3/Usp29 Transcription, Jeong Do Kim, Sungryul Yu, Jung Ha Choo, Joomyeong Kim

Faculty Publications

Background: Two evolutionarily Conserved Sequence Elements, CSE1 and CSE2 (YY1 binding sites), are found within the 3.8-kb CpG island surrounding the bidirectional promoter of two imprinted genes, Peg3 (Paternally expressed gene 3) and Usp29 (Ubiquitin-specific protease 29). This CpG island is a likely ICR (Imprinting Control Region) that controls transcription of the 500-kb genomic region of the Peg3 imprinted domain. Results: The current study investigated the functional roles of CSE1 and CSE2 in the transcriptional control of the two genes, Peg3 and Usp29, using cell line-based promoter assays. The mutation of 6 YY1 binding sites (CSE2) reduced the transcriptional activity …

Go to article

L1 Recombination-Associated Deletions Generate Human Genomic Variation, Kyudong Han, Jungnam Lee, Thomas J. Meyer, Paul Remedios, Lindsey Goodwin, Mark A. Batzer Dec 2008

L1 Recombination-Associated Deletions Generate Human Genomic Variation, Kyudong Han, Jungnam Lee, Thomas J. Meyer, Paul Remedios, Lindsey Goodwin, Mark A. Batzer

Faculty Publications

Mobile elements have created structural variation in the human genome through their de novo insertions and post-insertional genomic rearrangements. L1 elements are a type of long interspersed element (LINE) that is dispersed at high copy numbers within most mammalian genomes. To determine the magnitude of L1 recombination-associated deletions (L1RADs), we computationally extracted L1RAD candidates by comparing the human and chimpanzee genomes and verified each of the L1RAD events by using wet-bench analyses. Through these analyses, we identified 73 human-specific L1RAD events that occurred subsequent to the divergence of the human and chimpanzee lineages. Despite their low frequency, the L1RAD events …

Go to article

Low Energy Gamma-Ray Emission From Galactic Black Holes, Gary L. Case, Michael L. Cherry, James C. Ling, William A. Wheaton Dec 2008

Low Energy Gamma-Ray Emission From Galactic Black Holes, Gary L. Case, Michael L. Cherry, James C. Ling, William A. Wheaton

Faculty Publications

X-ray observations of Galactic black holes (GBHs) such as Cygnus X-1 have greatly advanced the understanding of these objects. However, the vast majority of the observations have been restricted to energies below ∼ 200 keV. The Compton Gamma-Ray Observatory (CGRO) allowed for the first time simultaneous observations at energies from ∼ 25 keV up to > 1 GeV. In particular, the BATSE experiment aboard CGRO was able to monitor low-energy gamma-ray emission from Cygnus X-1, as well as other GBHs, nearly continuously over a nine year period. Using the Enhanced BATSE Occultation Package (EBOP), light curves and spectra in the energy …

Go to article

Identification Of Adropin As A Secreted Factor Linking Dietary Macronutrient Intake With Energy Homeostasis And Lipid Metabolism, K. Ganesh Kumar, James L. Trevaskis, Daniel D. Lam, Gregory M. Sutton, Robert A. Koza, Vladimir N. Chouljenko, Konstantin G. Kousoulas, Pamela M. Rogers, Robert A. Kesterson, Marie Thearle, Anthony W. Ferrante, Randall L. Mynatt, Thomas P. Burris, Jesse Z. Dong, Heather A. Halem, Michael D. Culler, Lora K. Heisler, Jacqueline M. Stephens, Andrew A. Butler Dec 2008

Identification Of Adropin As A Secreted Factor Linking Dietary Macronutrient Intake With Energy Homeostasis And Lipid Metabolism, K. Ganesh Kumar, James L. Trevaskis, Daniel D. Lam, Gregory M. Sutton, Robert A. Koza, Vladimir N. Chouljenko, Konstantin G. Kousoulas, Pamela M. Rogers, Robert A. Kesterson, Marie Thearle, Anthony W. Ferrante, Randall L. Mynatt, Thomas P. Burris, Jesse Z. Dong, Heather A. Halem, Michael D. Culler, Lora K. Heisler, Jacqueline M. Stephens, Andrew A. Butler

Faculty Publications

Obesity and nutrient homeostasis are linked by mechanisms that are not fully elucidated. Here we describe a secreted protein, adropin, encoded by a gene, Energy Homeostasis Associated (Enho), expressed in liver and brain. Liver Enho expression is regulated by nutrition: lean C57BL/6J mice fed high-fat diet (HFD) exhibited a rapid increase, while fasting reduced expression compared to controls. However, liver Enho expression declines with diet-induced obesity (DIO) associated with 3 months of HFD or with genetically induced obesity, suggesting an association with metabolic disorders in the obese state. In DIO mice, transgenic overexpression or systemic adropin treatment attenuated hepatosteatosis and …

Go to article

Identification Of Adropin As A Secreted Factor Linking Dietary Macronutrient Intake With Energy Homeostasis And Lipid Metabolism, K. Ganesh Kumar, James L. Trevaskis, Daniel D. Lam, Gregory M. Sutton, Robert A. Koza, Vladimir N. Chouljenko, Konstantin G. Kousoulas, Pamela M. Rogers, Robert A. Kesterson, Marie Thearle, Anthony W. Ferrante, Randall L. Mynatt, Thomas P. Burris, Jesse Z. Dong, Heather A. Halem, Michael D. Culler, Lora K. Heisler, Jacqueline M. Stephens, Andrew A. Butler Dec 2008

Identification Of Adropin As A Secreted Factor Linking Dietary Macronutrient Intake With Energy Homeostasis And Lipid Metabolism, K. Ganesh Kumar, James L. Trevaskis, Daniel D. Lam, Gregory M. Sutton, Robert A. Koza, Vladimir N. Chouljenko, Konstantin G. Kousoulas, Pamela M. Rogers, Robert A. Kesterson, Marie Thearle, Anthony W. Ferrante, Randall L. Mynatt, Thomas P. Burris, Jesse Z. Dong, Heather A. Halem, Michael D. Culler, Lora K. Heisler, Jacqueline M. Stephens, Andrew A. Butler

Faculty Publications

Obesity and nutrient homeostasis are linked by mechanisms that are not fully elucidated. Here we describe a secreted protein, adropin, encoded by a gene, Energy Homeostasis Associated (Enho), expressed in liver and brain. Liver Enho expression is regulated by nutrition: lean C57BL/6J mice fed high-fat diet (HFD) exhibited a rapid increase, while fasting reduced expression compared to controls. However, liver Enho expression declines with diet-induced obesity (DIO) associated with 3 months of HFD or with genetically induced obesity, suggesting an association with metabolic disorders in the obese state. In DIO mice, transgenic overexpression or systemic adropin treatment attenuated hepatosteatosis and …

Go to article

Search For Charged Current Coherent Pion Production On Carbon In A Few-Gev Neutrino Beam, K. Hiraide, J. L. Alcaraz-Aunion, S. J. Brice, L. Bugel, J. Catala-Perez, G. Cheng, J. M. Conrad, Z. Djurcic, U. Dore, D. A. Finley, A. J. Franke, C. Giganti, J. J. Gomez-Cadenas, P. Guzowski, A. Hanson, Y. Hayato, G. Jover-Manas, G. Karagiorgi, T. Katori, Y. K. Kobayashi, T. Kobilarcik, H. Kubo, Y. Kurimoto, W. C. Louis, P. F. Loverre, L. Ludovici, K. B.M. Mahn, C. Mariani, S. Masuike, K. Matsuoka, W. Metcalf, G. Mills, G. Mitsuka Dec 2008

Search For Charged Current Coherent Pion Production On Carbon In A Few-Gev Neutrino Beam, K. Hiraide, J. L. Alcaraz-Aunion, S. J. Brice, L. Bugel, J. Catala-Perez, G. Cheng, J. M. Conrad, Z. Djurcic, U. Dore, D. A. Finley, A. J. Franke, C. Giganti, J. J. Gomez-Cadenas, P. Guzowski, A. Hanson, Y. Hayato, G. Jover-Manas, G. Karagiorgi, T. Katori, Y. K. Kobayashi, T. Kobilarcik, H. Kubo, Y. Kurimoto, W. C. Louis, P. F. Loverre, L. Ludovici, K. B.M. Mahn, C. Mariani, S. Masuike, K. Matsuoka, W. Metcalf, G. Mills, G. Mitsuka

Faculty Publications

The SciBooNE Collaboration has performed a search for charged current coherent pion production from muon neutrinos scattering on carbon, νμC12→μ-C12π+, with two distinct data samples. No evidence for coherent pion production is observed. We set 90% confidence level upper limits on the cross section ratio of charged current coherent pion production to the total charged current cross section at 0.67×10-2 at mean neutrino energy 1.1 GeV and 1.36×10-2 at mean neutrino energy 2.2 GeV. © 2008 The American Physical Society.

Go to article

First Measurement Of The Fraction Of Top-Quark Pair Production Through Gluon-Gluon Fusion, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, M. Aoki, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzi-Bacchetta, P. Azzurri, N. Bacchetta, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, S. Baroiant, V. Bartsch Dec 2008

First Measurement Of The Fraction Of Top-Quark Pair Production Through Gluon-Gluon Fusion, T. Aaltonen, J. Adelman, T. Akimoto, M. G. Albrow, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, M. Aoki, G. Apollinari, A. Apresyan, T. Arisawa, A. Artikov, W. Ashmanskas, A. Attal, A. Aurisano, F. Azfar, P. Azzi-Bacchetta, P. Azzurri, N. Bacchetta, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, S. Baroiant, V. Bartsch

Faculty Publications

We present the first measurement of σ(gg→tt̄)/ σ(pp̄→tt̄). We use 0.96fb-1 of s=1.96TeV pp̄ collision data recorded with the CDF II detector at Fermilab. Using charged particles with low transverse momentum in tt̄ events, we find σ(gg→ tt̄)/σ(pp̄→tt̄)=0.07±0.14(stat)±0. 07(syst), corresponding to a 95% confidence level upper limit of 0.33, in agreement with the standard model next-to-leading-order prediction of 0.15±0.05. © 2008 The American Physical Society.

Go to article

The Chinese Scramble In East Africa: The Growing Interest Of China In Uganda, Kenya, And Tanzania, Ara Jannie Jo Dec 2008

The Chinese Scramble In East Africa: The Growing Interest Of China In Uganda, Kenya, And Tanzania, Ara Jannie Jo

Honors Theses

No abstract provided.

Go to article

Rocking The Vote: An Analysis Of What Makes The Millennial Generation Vote And The Correlation Of Civic Engagement To Empathy, Gabrielle Michelle Martinez Dec 2008

Rocking The Vote: An Analysis Of What Makes The Millennial Generation Vote And The Correlation Of Civic Engagement To Empathy, Gabrielle Michelle Martinez

Honors Theses

No abstract provided.

Go to article

Prompt Optical Observations Of Grb 080330 And Grb 080413a, F. Yuan, E. S. Rykoff, B. E. Schaefer, W. Rujopakarn, T. Güver, F. Aharonian, C. W. Akerlof, M. C.B. Ashley, S. D. Barthelmy, N. Gehrels, E. Gögüş, D. Horns, Ü Kiziloǧlu, H. A. Krimm, T. A. Mckay, M. Özel, A. Phillips, R. M. Quimby, G. Rowell, H. F. Swan, W. T. Vestrand, J. C. Wheeler, J. Wren Dec 2008

Prompt Optical Observations Of Grb 080330 And Grb 080413a, F. Yuan, E. S. Rykoff, B. E. Schaefer, W. Rujopakarn, T. Güver, F. Aharonian, C. W. Akerlof, M. C.B. Ashley, S. D. Barthelmy, N. Gehrels, E. Gögüş, D. Horns, Ü Kiziloǧlu, H. A. Krimm, T. A. Mckay, M. Özel, A. Phillips, R. M. Quimby, G. Rowell, H. F. Swan, W. T. Vestrand, J. C. Wheeler, J. Wren

Faculty Publications

We report on the results of rapid responses to GRB 080330 and GRB 080413A by the ROTSE-IIIb and ROTSE-IIIc telecopes. In both cases, optical follow-up started during the prompt emission phase and recorded optical flares peaking at similar times as the last hard X-ray pulses detected by the Swift BAT. For both events, the XRT observations started at the end of the prompt BAT detection and displayed an evolution in time opposite to the optical lightcurve. These very early observations provide us an opportunity to probe the onset of afterglow for these two events. © 2008 American Institute of Physics.

Go to article

Host-Pathogen Interactions, Insect Outbreaks, And Natural Selection For Disease Resistance, Bret D. Elderd, Jonathan Dushoff, Greg Dwyer Dec 2008

Host-Pathogen Interactions, Insect Outbreaks, And Natural Selection For Disease Resistance, Bret D. Elderd, Jonathan Dushoff, Greg Dwyer

Faculty Publications

The theory of insect population dynamics has shown that heterogeneity in natural-enemy attack rates is strongly stabilizing. We tested the usefulness of this theory for outbreaking insects, many of which are attacked by infectious pathogens. We measured heterogeneity among gypsy moth larvae in their risk of infection with a nucleopolyhedrovirus, which is effectively heterogeneity in the pathogen's attack rate. Our data show that heterogeneity in infection risk in this insect is so high that it leads to a stable equilibrium in the models, which is inconsistent with the outbreaks seen in North American gypsy moth populations. Our data further suggest …

Go to article

Identification Of Two Genes, Sll0804 And Slr1306, As Putative Components Of The Co2-Concentrating Mechanism In The Cyanobacterium Synechocystis Sp. Strain Pcc 6803, Shulu Zhang, Kevin W. Spann, Laurie K. Frankel, James V. Moroney, Terry M. Bricker Dec 2008

Identification Of Two Genes, Sll0804 And Slr1306, As Putative Components Of The Co2-Concentrating Mechanism In The Cyanobacterium Synechocystis Sp. Strain Pcc 6803, Shulu Zhang, Kevin W. Spann, Laurie K. Frankel, James V. Moroney, Terry M. Bricker

Faculty Publications

Insertional transposon mutations in the sll0804 and slr1306 genes were found to lead to a loss of optimal photoautotrophy in the cyanobacterium Synechocystis sp. strain PCC 6803 grown under ambient CO2 concentrations (350 ppm). Mutants containing these insertions (4BA2 and 3ZA12, respectively) could grow photoheterotrophically on glucose or photoautotrophically at elevated CO2 concentrations (50,000 ppm). Both of these mutants exhibited an impaired affinity for inorganic carbon. Consequently, the Sll0804 and Slr1306 proteins appear to be putative components of the carbon-concentrating mechanism in Synechocystis sp. strain PCC 6803. Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Go to article

Escherichia Coli Ftna Acts As An Iron Buffer For Re-Assembly Of Iron-Sulfur Clusters In Response To Hydrogen Peroxide Stress, Jacob P. Bitoun, Genfu Wu, Huangen Ding Dec 2008

Escherichia Coli Ftna Acts As An Iron Buffer For Re-Assembly Of Iron-Sulfur Clusters In Response To Hydrogen Peroxide Stress, Jacob P. Bitoun, Genfu Wu, Huangen Ding

Faculty Publications

Iron-sulfur clusters are one of the most ubiquitous redox centers in biology. Ironically, iron-sulfur clusters are highly sensitive to reactive oxygen species. Disruption of iron-sulfur clusters will not only change the activity of proteins that host iron-sulfur clusters, the iron released from the disrupted iron-sulfur clusters will further promote the production of deleterious hydroxyl free radicals via the Fenton reaction. Here, we report that ferritin A (FtnA), a major iron-storage protein in Escherichia coli, is able to scavenge the iron released from the disrupted iron-sulfur clusters and alleviates the production of hydroxyl free radicals. Furthermore, we find that the iron …

Go to article

Tfiiic Binding Sites Function As Both Heterochromatin Barriers And Chromatin Insulators In Saccharomyces Cerevisiae, Tiffany A. Simms, Sandra L. Dugas, Jason C. Gremillion, Megan E. Ibos, M. Nicole Dandurand, Tasha T. Toliver, Daniel J. Edwards, David Donze Dec 2008

Tfiiic Binding Sites Function As Both Heterochromatin Barriers And Chromatin Insulators In Saccharomyces Cerevisiae, Tiffany A. Simms, Sandra L. Dugas, Jason C. Gremillion, Megan E. Ibos, M. Nicole Dandurand, Tasha T. Toliver, Daniel J. Edwards, David Donze

Faculty Publications

Chromosomal sites of RNA polymerase III (Pol III) transcription have been demonstrated to have "extratranscriptional" functions, as the assembled Pol III complex can act as chromatin boundaries or pause sites for replication forks, can alter nucleosome positioning or affect transcription of neighboring genes, and can play a role in sister chromatid cohesion. Several studies have demonstrated that assembled Pol III complexes block the propagation of heterochromatin-mediated gene repression. Here we show that in Saccharomyces cerevisiae tRNA genes (tDNAs) and even partially assembled Pol III complexes containing only the transcription factor TFIIIC can exhibit chromatin boundary functions both as heterochromatin barriers …

Go to article

Preface Dec 2008

Preface

Communications on Stochastic Analysis

No abstract provided.

Go to article

General Equilibrium Asset Pricing Under Regime Switching, Robert J Elliott, Hong Miao, Jin Yu Dec 2008

General Equilibrium Asset Pricing Under Regime Switching, Robert J Elliott, Hong Miao, Jin Yu

Communications on Stochastic Analysis

No abstract provided.

Go to article

A Decomposition Of Multiple Wiener Integrals By The Lévy Process And Lévy Laplacian, Atsushi Ishikawa Dec 2008

A Decomposition Of Multiple Wiener Integrals By The Lévy Process And Lévy Laplacian, Atsushi Ishikawa

Communications on Stochastic Analysis

No abstract provided.

Go to article

Errata: Existence And Uniqueness Of Solutions To The Backward Stochastic Lorenz System (Cosa, Vol. 1, No. 3 (2007) 473–483) [Mr2403863], P Sundar, Hong Yin Dec 2008

Errata: Existence And Uniqueness Of Solutions To The Backward Stochastic Lorenz System (Cosa, Vol. 1, No. 3 (2007) 473–483) [Mr2403863], P Sundar, Hong Yin

Communications on Stochastic Analysis

No abstract provided.

Go to article

Limits Of Bifractional Brownian Noises, Makoto Maejima, Ciprian A Tudor Dec 2008

Limits Of Bifractional Brownian Noises, Makoto Maejima, Ciprian A Tudor

Communications on Stochastic Analysis

No abstract provided.

Go to article

A Class Of Extreme X-Harmonic Functions, John Verzani Dec 2008

A Class Of Extreme X-Harmonic Functions, John Verzani

Communications on Stochastic Analysis

No abstract provided.

Go to article

Applicability Of Multiplicative Renormalization Method For A Certain Function, Izumi Kubo, Hui-Hsiung Kuo, Suat Namli Dec 2008

Applicability Of Multiplicative Renormalization Method For A Certain Function, Izumi Kubo, Hui-Hsiung Kuo, Suat Namli

Communications on Stochastic Analysis

No abstract provided.

Go to article

An Extension Of The Itô Integral, Wided Ayed, Hui-Hsiung Kuo Dec 2008

An Extension Of The Itô Integral, Wided Ayed, Hui-Hsiung Kuo

Communications on Stochastic Analysis

No abstract provided.

Go to article

Locally Integrable Processes With Respect To Locally Additive Summable Processes, Oana Mocioalca Dec 2008

Locally Integrable Processes With Respect To Locally Additive Summable Processes, Oana Mocioalca

Communications on Stochastic Analysis

No abstract provided.

Go to article

Next Last