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Effects Of Selected Polycyclic Aromatic Hydrocarbons On Cell Proliferation, Protein Phosphorylation, And Intracellular Calcium Concentration In Lepomis Macrochirus., Helen Runnels Connelly
Effects Of Selected Polycyclic Aromatic Hydrocarbons On Cell Proliferation, Protein Phosphorylation, And Intracellular Calcium Concentration In Lepomis Macrochirus., Helen Runnels Connelly
LSU Historical Dissertations and Theses
Polycyclic aromatic hydrocarbons (PAH) have been demonstrated to affect signal transduction in higher vertebrates. In this research, the freshwater species of fish, Lepomis macrochirus (bluegill) was used to test the effects of a 14-day diet of PAH on lymphocyte signal transduction. PAH tested included: 2-aminoanthracene (2-AA), 2-methylnaphthalene (2-MN), 9,10-dimethylanthracene (9,10-DMA), and a mixture of these three compounds (MIX). Individual compounds were tested at a total PAH dose of 3.1 $\pm$ 0.01mg over the 14 day period. The MIX diet was a total PAH dose of 0.13 $\pm$ 0.01mg 2-AA, 0.19 + 0.01mg 9,10-DMA, and 0.22 $\pm$ 0.02mg 2-MN over the …
Evaluation Of The Toxicological Consequences Of Dietary Exposure To Individual Classes Of Polycyclic Aromatic Hydrocarbons Or A Mixture In The Fischer-344 Rat., Mary Durand Boudreau
Evaluation Of The Toxicological Consequences Of Dietary Exposure To Individual Classes Of Polycyclic Aromatic Hydrocarbons Or A Mixture In The Fischer-344 Rat., Mary Durand Boudreau
LSU Historical Dissertations and Theses
There is special concern about the potential health effects of by-products released into the environment after combustion or conversion of fossil fuels. Polycyclic aromatic hydrocarbons (PAH), while initially released largely into the atmosphere, are subsequently deposited in soil and water and on foods. Although the significance of PAH contamination with regard to environmentally caused diseases and cancer in humans is difficult to estimate, it is suggested that the potential hazards may be underestimated. In an effort to understand the potential adverse health effects of PAHs, a comprehensive study was undertaken to determine the metabolic fate of selected PAHs as individual …
The Effect Of Pulmonary Infection (Actinobacillus Pleuropneumoniae), Endotoxin And Dexamethasone On Enrofloxacin Pharmacokinetic Parameters In Swine., Lynn O. Post
LSU Historical Dissertations and Theses
Efficacy studies are often done on diseased animals while pharmacokinetic studies are done on healthy animals. Disease models are inherently difficult to standardize because of the many variables associated with measuring pharmacokinetic parameters in abnormal animals. Information derived from pharmacokinetic studies with diseased animals could be useful to determine if therapeutic doses of a drug or antimicrobial becomes less effective or toxic due to changes in distribution and clearance. The objectives of this study were to: characterize a pulmonary infection model in swine using Actinobacillus pleuropneumoniae; evaluate the pharmacokinetic changes associated with the pulmonary infection model and dexamethasone after the …
Association Of Environmental And Climatic Factors In The Epidemiology Of American Visceral Leishmaniasis In Northeast Brazil Using Remote Sensing And Geographical Information System Methods., Roland Alexander Thompson
Association Of Environmental And Climatic Factors In The Epidemiology Of American Visceral Leishmaniasis In Northeast Brazil Using Remote Sensing And Geographical Information System Methods., Roland Alexander Thompson
LSU Historical Dissertations and Theses
This study associated climatic and environmental factors with the incidence of visceral leishmaniasis (calazar) in Northeast Brazil. Remote sensing (RS) techniques permitted evaluation of spatial and temporal landscape features to stratify the region and define the target population for this vector-borne disease. The Municipality of Caninde, Ceara, Brazil was divided into 873-- 2 x 2 km2 squares centered on coordinates from a Universal Transverse Mercator projection (scale 1:100,000, 1994) and geo-referenced with 2 Landsat T.M. (TM) scenes (September 26, 1976 and July 2, 1996). The assignment of squares into foothills, plains or city strata was based on vegetative categories determined …
Perception-Action Coupling During Goal-Directed Locomotion Without Vision., Robert D. Clark
Perception-Action Coupling During Goal-Directed Locomotion Without Vision., Robert D. Clark
LSU Historical Dissertations and Theses
The ability to walk to distant targets accurately without the use of vision has been demonstrated in a number of studies (e.g., Elliott, 1987; 1990; Loomis, Da Silva, Philbeck, & Fukusima, 1996; Rieser, Ashmead, Talor, & Youngquist, 1990; Steenhuis & Goodale 1988; Thomson, 1983). Processes underlying the mechanisms involved in this ability however, are not completely understood. One possible mechanism examined involves non-visual sensory flows during locomotion. In Experiment 1, manipulations to normal walking led to significant increases in error relative to the control group. Error expressed as a percentage of target distance revealed that target distance did not affect …
The Physiological And Psychological Responses To Submaximal Exercise At Different Times In Renal Disease Patients., Marta Amaral-Melendez
The Physiological And Psychological Responses To Submaximal Exercise At Different Times In Renal Disease Patients., Marta Amaral-Melendez
LSU Historical Dissertations and Theses
This study investigated cardiorespiratory, hematological, and psychological responses to acute submaximal exercise, and recovery in end stage renal disease patients. Five African-American males on hemodialysis, were randomly assigned to three exercise treatments (30 minutes on the treadmill at 60% VO$\sb2$ peak): pre dialysis (2 hours before), post dialysis (1 hour after), and off dialysis (24 hours after last dialysis). The cardiorespiratory (CR) variables were: ventilation (V$\sb{\rm E}$), oxygen consumption (VO$\sb2$), carbon dioxide production (VCO$\sb2$), respiratory exchange ratio (R), and kilocalories (KCAL/min). The hematological variables were: blood urea nitrogen (BUN), creatinine (Cr), albumin (Al), total protein (Tp), glucose (Gl), sodium (Na$\sp{++}$), …
Purification And Antioxidant Properties Of Rice Bran (Gamma)-Oryzanol Components., Zhimin Xu
Purification And Antioxidant Properties Of Rice Bran (Gamma)-Oryzanol Components., Zhimin Xu
LSU Historical Dissertations and Theses
A high purity $\gamma$-oryzanol was obtained from crude rice bran oil using a normal phase preparative scale HPLC. It was used in implementing a reverse phase HPLC method for separating each individual component of $\gamma$-oryzanol present in rice bran oil. Ten fractions were isolated in the reverse phase HPLC method. The ten components of $\gamma$-oryzanol were identified. Three of these, cycloartenyl ferulate, 24-methylene cycloartanyl ferulate, and campesteryl ferulate, were major components of $\gamma$-oryzanol. The yield of $\gamma$-oryzanol without saponification was significantly higher than that with saponification in solvent extraction. The solvent mixture with 50% hexane and 50% isopropanol (v/v.) at …
Using Scaffolded Interaction To Improve Lld Readers' Inferencing And Narrative Abilities., Kathryn Patrice Dekemel
Using Scaffolded Interaction To Improve Lld Readers' Inferencing And Narrative Abilities., Kathryn Patrice Dekemel
LSU Historical Dissertations and Theses
A time series control group study was completed to investigate the efficacy of Communicative Reading Strategies (CRS) as an instructional approach for improving the oral reading, question answering, and narrative retelling abilities of LLD students. The participants were 10 LLD students who ranged in age from 9 to 12 years and 5 reading-age matched (RAM) peers who ranged in age from 7 to 9 years. Five of the LLD subjects were randomly assigned to a treatment group (TLD), while the remaining 5 LLD subjects were assigned to a no-treatment group (NLD). All three groups participated in a series of probes …
A Comparative Study Of Communication Intervention For Nonverbal Children With Autism., Kelly C. Higgins
A Comparative Study Of Communication Intervention For Nonverbal Children With Autism., Kelly C. Higgins
LSU Historical Dissertations and Theses
Communication intervention for 3 nonverbal children with autism was compared in an alternating treatment design. Subjects were three males, ages 4--7, 3--6, and 3--5 who met diagnostic criteria for Autism and who were considered to be nonverbal according to developmental history, parent/teacher report and behavioral observation. Alternating treatment conditions included the established treatment format that each subject was receiving in his school setting (Treatment A) and a developmentally-integrated format of intervention structured to facilitate integrated cognitive, social and communicative development (Treatment B). Each intervention was characterized according to profiles of Traditional-Behavioral or Semantic Pragmatic-Developmental intervention formats. Characteristics of adult interaction …
Beta-Carotene And Exercise Performance: Effects On Race Performance, Oxidative Stress, And Maximal Oxygen Consumption., Kim Edward Leblanc
Beta-Carotene And Exercise Performance: Effects On Race Performance, Oxidative Stress, And Maximal Oxygen Consumption., Kim Edward Leblanc
LSU Historical Dissertations and Theses
There is evidence in the literature that suggests a possible worthwhile role of antioxidants during athletic endeavors and exercise performance. Several studies have evaluated the antioxidant ability of beta-carotene and demonstrated a beneficial influence. However, these studies have investigated beta-carotene's effects within an antioxidant mixture which included other antioxidant vitamins. Consequently, this study attempted to isolate the antioxidant role of beta-carotene during exercise. Three parameters of beta-carotene influence were measured using eleven well-trained runners: serum malondialdehyde (MDA) concentration (a marker of free radical generation), 5000 meter race performance, and maximum oxygen consumption (VO2max). Subjects were tested using a double-blinded cross-over …