Digital Commons Network^™

Inter-Institutional Analysis Of Skin Of Color Representation In Dermatological Lecture Content At Md And Do Medical Schools, Oluwafunke O. Ogunremi, Blake Fredericksen, John Komas, Sana F. Ismail, Siri Knusten-Larson, Valeriy Kozmenko, Afia Albin

Student Publications

The purpose of this study was to analyze the lecture materials provided in medical schools through a diversity lens. Skin pathologies manifest distinctively on various shades of skin and physicians must be equipped with the proper knowledge to identify and diagnose these conditions accurately and promptly. For most medical students, images in prominent textbooks and lecture slides are their first encounter with disease presentations. Therefore, it is important to analyze the diversity of skin tones in the content that is being delivered. Specifically, the use of images featuring darker skin tones compared to those depicting lighter skin tones. This study …

Morphological Variation Of The Soleus Muscle: Determining General Patterns And Characteristics Of The Connective Tissue Architecture, Keanna Theobalt, Miles Turk, George Kalu, Robert Steele, Charles B. Withnell

GME Publications

Background

The tendons within the soleus muscle are commonly utilized to delineate location of injury for soleus muscle strains. Strains within the soleus frequently involve the myotendinous (MTJ) or myofascial (MFJ) junctions, although spatial relationship between these tendinous structures are not well understood. This study aimed to structurally identify the MTJs and MFJs within the soleus as a starting point to understanding the distribution of connective tissue for further anatomical classification.

Methods

Forty (n = 40) soleus muscles, representing left and right sides from twenty (n = 20) formalin-embalmed cadavers (average age 78 years old; 10 males, 10 females) were …

Location And Function Of Tdp-43 In Platelets, Alterations In Neurodegenerative Diseases And Arising Considerations For Current Plasma Biobank Protocols, Ruth Luthi-Carter, Sara Cappelli, Morgan Le Roux-Bourdieu, Noemie Tentillier, James P. Quinn, Tiziana Petrozziello, Lathika Gopalakrishnan, Purva Sethi, Himanshi Choudhary, Giorgia Bartolini, Elias Gebara, Cristiana Stuani, Laure Font, Jiyan An, Vanessa Ortega, Jessica Sage, Edina Kosa, Bianca A. Trombetta, Roberto Simeone, Tamara Seredenina, Tariq Afroz, James D. Berry, Steven E. Arnold, Becky C. Carlyle, Oskar Adolfsson, Ghazaleh Sadri-Vakili, Emanuele Buratti, Robert Bowser, Abdulbaki Agbas

Faculty Publications

The TAR DNA Binding Protein 43 (TDP-43) has been implicated in the pathogenesis of human neurodegenerative diseases and exhibits hallmark neuropathology in amyotrophic lateral sclerosis (ALS). Here, we explore its tractability as a plasma biomarker of disease and describe its localization and possible functions in the cytosol of platelets. Novel TDP-43 immunoassays were developed on three different technical platforms and qualified for specificity, signal-to-noise ratio, detection range, variation, spike recovery and dilution linearity in human plasma samples. Surprisingly, implementation of these assays demonstrated that biobank-archived plasma samples yielded considerable heterogeneity in TDP-43 levels. Importantly, subsequent investigation attributed these differences to …

Unraveling The Puzzle: A Case Of Intricate Neurological Presentation Attributable To Hypomagnesemia, Syed H. Hussain, Mohammed Zaidi, Mariam Zaidi, Guy M. Grabau

Student Publications

Hypomagnesemia can occasionally present with severe neurological deficiencies, and it is usually attributed to an underlying renal and/or gastrointestinal pathology. Rarely, patients may present with neurological symptoms in the absence of an obvious cause. Our case highlights the importance of considering hypomagnesemia as a primary cause of those presenting with severe neurological deficits in an intensive care unit setting, as well as the significance of conducting a thorough social and medical history on these patients to elucidate their underlying causes. We discuss the case of a 48-year-old Caucasian male who acutely presented with seizures, tremors, visual hallucinations, diplopia, personality changes, …

Exploring The Intersection Of Body Dysmorphic Disorder (Bdd) And Dermatological Conditions: A Narrative Review, Vivian Li, Kelly Frasier, Emily Woolhiser, Kathleen Daly, Sara Christoforides, Courtnee Harpine, Karina Stech, Stefany Acosta, Edwin D. Lephart

Student Publications

This narrative literature review examined the intricate relationship between body dysmorphic disorder (BDD) and dermatological conditions, with a brief focus on those characterized by conspicuous skin irregularities such as acne vulgaris, psoriasis, and vitiligo. Highlighting the significant prevalence of BDD among individuals afflicted with dermatological issues, our analysis illuminated the profound psychological repercussions stemming from an exaggerated preoccupation with perceived skin imperfections. Through an exploration of the underlying BDD symptoms, we analyzed the complex dynamics between skin health and mental well-being, emphasizing the disorder's impact on patients' psychological and social functioning. This narrative review further investigated the consequential effects of …

Analysis Of Causes For Revision In Unicompartmental Knee Arthroplasty, Sujit Tripathy, Siddharth Satyakam Pradhan, Shahnawaz Khan, Hursch Patel

Student Publications

The study by Zhao et al identifies the factors leading to the failure of unicompartmental knee arthroplasty (UKA) in their patients. These factors include substandard suturing of the wound, the presence of osteophytes and intra-articular loose bodies causing impingement, premature loosening of the tibial component, choosing unsuitable patients for the procedure, dislocation of the movable insert, and damage to the anterior cruciate ligament and medial collateral ligament. The findings suggest that employing the correct surgical techniques and indications is essential for successful outcomes in the UKA.

A Systematic Review Of Phenibut Withdrawals, Christopher Stewart, Hunter Simonsen, Savitha K. Satyasi, Nauman Ashraf, Suporn Sukpraprut-Braaten

Student Publications

Phenibut is an anxiolytic agent that was originally used as a treatment for anxiety, depression, post-traumatic stress disorder (PTSD), and insomnia. It is a gamma-aminobutyric acid (GABA) mimetic, which stimulates GABA receptors in the brain. This increases the inhibitory effects of GABA leading to a greater chance of a sedative response and risk for abuse. It is not currently registered in Western countries but is easily accessible online as a supplement. This is a systematic review of case reports of phenibut patients with withdrawal symptoms published in the PubMed database between January 2010 and October 2023. Following the inclusion criteria …

Rural Adolescent Attitudes And Use Of Helmets While Riding Atvs, Motorcycles And Dirt Bikes, Charles A. Jennissen, Sehansa R. Karunatilaka, Brianna J. Iverson, Devin E. Spolsdoff, Kristel M. Wetjen, Brenda Vergara, Shannon R. Landers, Pam J. Hoogerwerf

Student Publications

Background: Head injuries are the most common cause of death in some motorized vehicles for which helmet use can significantly decrease the risk. Our objective was to determine rural adolescents' attitudes regarding helmets and their use while riding ATVs, motorcycles and dirt bikes.

Methods: A convenience sample of 2022 Iowa FFA (formerly Future Farmers of America) Leadership Conference attendees were surveyed. After compilation, data were imported into the statistical program, R ( https://www.R-project.org/ ). Descriptive statistics, contingency table, logistic regression and non-parametric alternatives to ANOVA analyses were performed.

Results: 1331 adolescents (13-18 years) participated. One half lived on a farm, …

Patients Undergoing Revision Hip Arthroscopy With Labral Reconstruction Or Labral Repair And Patient-Reported Outcomes: A Systematic Review, Nancy Park, Trevan Klug, Seema Patel, Serkan Surucu, Michael S. Lee, Kian Kardestuncer, Mackenzie Norman, Justin Zhu, Nicholas Pettinelli, Maxwell Modrak, Andrew E. Jimenez

Student Publications

Background: Compromise of the acetabular labrum can lead to pain and loss of critical intra-articular fluid pressure. Revision labral preservation poses unique challenges due to adhesions and compromised tissue quality.

Purpose/Hypothesis: The purpose of the study was to evaluate patient-reported outcome (PRO) measures (PROMs) in patients undergoing revision hip arthroscopy with either labral reconstruction or labral repair after primary hip arthroscopy for labral tear. It was hypothesized that both procedures would lead to improved PROs.

Study Design: Systematic review; Level of evidence, 4.

Methods: A systematic review of the literature was conducted with the following keywords: (revision) AND (hip OR …

Geographical Distribution Of Osteopathic Neurosurgery Residents, Ogechukwu Ariwodo, Andrew Greek, Ryan Wong, Vincent S. Alexander, Andrew D. Vogel, Bracken Burns, Kristen Conrad-Schnetz

Student Publications

Introduction: The neurosurgery residency match has grown increasingly competitive, especially for osteopathic (DO) medical students, amidst the transition to a single accreditation system in 2020. This shift required former American Osteopathic Association (AOA) programs to apply for Accreditation Council for Graduate Medical Education (ACGME) accreditation, leading to a notable reduction in programs with a history of accepting DO applicants. This study aims to explore both potential geographical trends in residency match among recent DO neurosurgical residents and in the number of DO neurosurgical residents pre- and post-ACGME merger.

Methods: Neurosurgery residency programs during the 2023-2024 academic year were identified, and …

Lumbar Disc Herniation With Radiculopathy: A Comparison Of Nass Guidelines And Chatgpt, Ankur Kayastha, Kirthika Lakshmanan, Michael J. Valentine, Anh Nguyen, Kaushal Dholakia, Daniel Wang

Student Publications

Background:

ChatGPT is an advanced language AI able to generate responses to clinical questions regarding lumbar disc herniation with radiculopathy. Artificial intelligence (AI) tools are increasingly being considered to assist clinicians in decision-making. This study compared ChatGPT-3.5 and ChatGPT-4.0 responses to established NASS clinical guidelines and evaluated concordance.

Methods:

ChatGPT-3.5 and ChatGPT-4.0 were prompted with fifteen questions from The 2012 NASS Clinical Guidelines for the diagnosis and treatment of lumbar disc herniation with radiculopathy. Clinical questions organized into categories were directly entered as unmodified queries into ChatGPT. Language output was assessed by two independent authors on September 26, 2023 based …

Histopathological Evaluation Of Geriatric Ophthalmic Veins: A Cadaveric Study, Farida Mehrhoff, Keanna Theobalt, Alla G. Barry, Robert Hillard

Student Publications

Context: The ophthalmic vein (OV) has become a source of increasing curiosity since many aspects of vascular surgery of the orbit have become feasible. At the same time, histochemical analysis of veins, in general, tends to skip the OV. Moreover, age‑related changes in the OVs remain untouched. Aims: Our research explores features of aging in the OV. Settings and Design: We immunohistochemically evaluated the superior and inferior OVs in 49 orbits of 28 formalin‑embalmed human cadavers (age 77.86 ± 13.38) without visible vascular malformations. Materials and Methods: Specimens were stained by hematoxylin and eosin. Verhoeff, laminin, and CD31 stains were …

Dose-Dependent Cranial Irradiation Associations With Brain Structures And Neuropsychological Outcomes In Children With Posterior Fossa Brain Tumors, Mary Baron Nelson, Sharon O'Neil, Scarlet J. Cho, Sofia Dhanani, Jeffrey Tanedo, Brandon Shin, Jack Rodman, Arthur Olch, Kenneth Wong, Marvin D. Nelson Jr., Jonathan Finlay, Natasha Lepore

Student Publications

Background: Posterior fossa irradiation with or without whole brain irradiation results in high doses of radiation to the thalamus, hippocampus, and putamen, structures critical to cognitive functioning. As a result, children with brain tumors treated with cranial irradiation (CRT) may experience significant cognitive late effects. We sought to determine the effect of radiation to those structures on neuropsychological outcome.

Methods: Forty-seven children with a history of posterior fossa tumor (17 treated with surgery; 11 with surgery and chemotherapy; and 19 with surgery, chemotherapy, and CRT) underwent neuroimaging and neuropsychological assessment at a mean of 4.8 years after treatment, along with …

Calyceal Rupture Secondary To Nephrolithiasis: A Case Report Emphasizing Early Diagnosis And Management, Gabriel Cruz, Daniel T. Jones, Maria Theresa Lugue, Manvir S. Heer, Christopher Pace, Linsey Bui, Scott A. Silver

Student Publications

Calyceal rupture, defined as the extravasation of urine from the renal calyces into the perinephric or paranephric spaces, typically results from increased intrapelvic pressure due to urinary tract obstruction. This condition can lead to the formation of a perinephric urinoma and severe complications, such as infection, abscess formation, and impaired renal function. Timely diagnosis and management are crucial to prevent these adverse outcomes. Calyceal rupture often results from urolithiasis, with other causes including strictures, tumors, and congenital abnormalities. The rupture occurs when intrapelvic pressure exceeds the tensile strength of the calyceal walls, leading to urine leakage and potential inflammation or …

Fruquintinib-Induced Cerebellar Hemorrhage In Left-Sided Descending Metastatic Colorectal Adenocarcinoma: A Case Report And Risk Assessment, Daniel T. Jones, Gabriel Cruz, Maria Theresa Lugue, Manvir S. Heer, Marlai Sai, Christopher Pace, Linsey Bui, Scott A. Silver

Student Publications

Colorectal adenocarcinoma is the most prevalent form of colorectal cancer, representing the majority of cases in the United States. The disease is driven by a series of genetic mutations, including alterations in the adenomatous polyposis coli (APC), Kirsten rat sarcoma viral oncogene homolog G12D (KRAS), human epidermal growth factor receptor 2 immunohistochemistry 3+ (HER-2 IHC3+), checkpoint kinase 2 (CHEK-2) and tumor protein P53 (TP53) genes, which lead to malignant transformation. While the standard treatment for metastatic colorectal cancer (mCRC) typically involves chemotherapy and targeted therapies, many patients experience disease progression, necessitating the exploration of novel treatments. Fruquintinib, a highly selective …

Stone Heart Syndrome: A Curious Case Of Digoxin Toxicity And Calcium Infusion, Guleid Hussein, Peter Krastev, Arvin Junn P. Mallari, Mohamad El Labban, Sumeet Yadav, Mohamed Hassan, Mohamed Warsame, Greta Zoesch, John Trnka, Nikhil Vojjala, Shika M. Jain, Salim Surani, Syed Anjum Khan

Student Publications

Stone heart syndrome has a complex interaction with digoxin toxicity, where, theoretically, the administration of intravenous calcium can worsen a patient's condition. Research on this subject is conflicting, so it is imperative to approach it cautiously.

A Rare Case Report Of Paratesticular Leiomyosarcoma, Santosh Nimkar, Bianca M. Glass, Samir Dalia

Student Publications

A leiomyosarcoma (LMS) is a malignant mesenchymal tumor of soft tissue that rarely presents in the scrotal region. This case report describes a primary paratesticular LMS originating in the dartos layer of the scrotum in a symptomatic 37-year-old male with a history of hypertension, generalized seizure disorder post-excision of meningioma, and an extensive family history of cancer. Primary paratesticular LMSs in the superficial dartos layer are exceedingly rare. Given the rarity of this particular type of LMS, this case report includes a discussion on its prevalence and incidence. The rarity of this tumor also warrants a review of the literature …

Severe Pneumatosis Intestinalis And Hepatic Portal Venous Gas In A Patient With Methamphetamine Use: Early Recognition And Management, Maria Theresa Lugue, Gabriel Cruz, Daniel T. Jones, Manvir S. Heer, Linsey Bui, Christopher Pace, Scott A. Silver

Student Publications

Pneumatosis intestinalis (PI) and hepatic portal venous gas (HPVG) are rare but potentially life-threatening conditions characterized by the presence of gas within the bowel wall and portal venous system, respectively. This case report presents a 45-year-old male with a history of methamphetamine use who developed severe metabolic and hemodynamic instability, marked by altered mental status, metabolic acidosis, and ST elevations. Despite aggressive resuscitation and intensive care, the patient unfortunately succumbed to his condition, highlighting the gravity of these complications. This report underscores the importance of early recognition, comprehensive management, and timely surgical consultation to improve outcomes. It also emphasizes the …

Persistent Left-Sided Superior Vena Cava: A Case Report, Matthew Hentges, Karson Schroeder, Aleesha Somani

GME Publications

A persistent left-sided superior vena cava (PLSVC) is the most common thoracic venous anomaly. However, it is still quite rare in the general population. PLSVC occurs during the embryological stages and is seen mostly in patients with congenital heart disease. Normally during development, the left anterior cardinal vein will regress and obliterate to form the ligament of Marshall. In cases of PLSVC, the left anterior cardinal vein persists and can become a persistent left superior vena cava (SVC). There are different anatomical variants of a left-sided SVC, most commonly presenting with both a right and a left SVC. In some …

Selective Androgen Receptor Modulators Leading To Liver Injury: A Case Report, Michael R. Demangone, Karam R. Abi Karam, Joshua Li

Student Publications

Selective androgen receptor modulators (SARMs) have gained popularity for their alleged ability to selectively target androgen receptors, potentially offering muscle-building benefits with fewer side effects than traditional steroids. However, the safety profile of SARMs, including RAD-140, is not fully understood. This case report presents a 29-year-old male who developed liver injury after taking RAD-140. The patient experienced jaundice and elevated liver enzymes after three months of RAD-140 use. A liver ultrasound revealed hepatic steatosis and a hyperechoic lesion. Symptoms resolved after discontinuing RAD-140. Similar cases of liver injury associated with RAD-140 have been reported, highlighting the potential hepatotoxicity of this …

Future Prospects Of Metabolic And Bariatric Surgery: A Comprehensive Review, Karl Hage, Gerardo Perrotta, Richard S. Betancourt, Jamil Danaf, Aryan Gajjar, Daniel Tomey, Katie Marrero, Omar M. Ghanem

Student Publications

Background: The field of metabolic and bariatric surgery (MBS) is currently an expanding surgical field with constant refinements in techniques, outcomes, indications, and objectives. MBS has been effectively applied across diverse patient demographics, including varying ages, genders, body mass indexes, and comorbidity statuses.

Methods: We performed a comprehensive literature review of published retrospective cohort studies, meta-analyses, systematic reviews, and literature reviews from inception to 2024, reporting outcomes of MBS using databases such as PubMed, ScienceDirect, and Springer Link.

Results: MBS is a safe and efficient therapeutic option for patients with obesity and associated medical conditions (mortality rate 0.03-0.2%; complication rates …

Anatomical Considerations For The Use Of The Popliteal Vein As A Potential Alternative For Central Venous Cannulation, Aaron Graves, Charles R. Marchese, Bradley A. Creamer, Jennifer F. Dennis

Student Publications

Limited reports have evaluated the utility of the popliteal vein (PV) specific to cannulation. The objective of this study was to characterize the diameter and length of the PV to evaluate this area as a potential cannulation site. The popliteal region in 23 formalin-embalmed, prosected donors was dissected, and the PV was exposed from the adductor hiatus (AH) superiorly to the small saphenous vein (SSV) inferiorly. The diameter of the popliteal vein was measured at the AH, SSV, and half of the distance from the AH to the SSV (MID) using a brass plumb bob. The length of the PV …

Beaton And Anson Type A Classification Of The Sciatic Nerve And Piriformis Complex: Clinical Considerations For Sex And Laterality, Charles R. Marchese, Aaron Graves, Benjamin J. Pautler, David Dye, Bradley A. Creamer, Jennifer F. Dennis

Student Publications

Variations of the sciatic nerve and piriformis muscle (SN-PM) relationship must be considered when discussing orthopedic procedures within the region as they may cause increased risk of SN injuries. Thirty-one formalin-embalmed, prosected donors were evaluated using the Beaton and Anson (B&A) classification system (1939). Major landmarks of the SN-PM relationship were identified, including the posterior superior iliac spine (PSIS), ischial tuberosity (IT), greater trochanter (GT), and the middle of the SN as it exits under the PM (S1). Distances measured included: PSIS-IT, PSIS-GT, IT-GT, PSIS-S1, IT-S1, GT-S1, S1-Q (distance of perpendicular line connecting S1 to PSIS-IT), and S1-R (distance of …

Comparative Treatment Of Homeless Persons With An Infectious Disease In The Us Emergency Department Setting: A Retrospective Approach, Jessica Barnes, Larry Segars, Jason A. Wasserman, Patrick Karabon, Tracey A.H. Taylor

Faculty Publications

Background: Research has long documented the increased emergency department usage by persons who are homeless compared with their housed counterparts, as well as an increased prevalence of infectious diseases. However, there is a gap in knowledge regarding the comparative treatment that persons who are homeless receive. This study seeks to describe this potential difference in treatment, including diagnostic services tested, procedures performed and medications prescribed.

Methods: This study used a retrospective, cohort study design to analyse data from the 2007-2010 United States National Hospital Ambulatory Medical Care Survey database, specifically looking at the emergency department subset. Complex sample logistic regression …

An Investigation Of Mortality Associated With Comorbid Pneumonia And Thrombocytopenia In A Rural Southwest Missouri Hospital System, Tabitha Ranson, Hannah Rourick, Rajbir Sooch, Nicole R. Ford, Nova Beyersdorfer, Kerry Johnson, John Paulson

Faculty Publications

Background: Pneumonia places a significant burden on individuals and society, contributing to a substantial number of hospital admissions, emergency department visits, deaths, and healthcare costs each year. Comorbidities can greatly increase the risk of poor outcomes when associated with pneumonia. One comorbidity that has yet to be thoroughly researched is thrombocytopenia, which is known to play an important role in activating the immune response to infections. A decrease in platelet count may limit the immune response and consequently increase mortality in patients with pneumonia. The purpose of this study was to investigate whether comorbid thrombocytopenia and pneumonia are associated with …

Veterinary Students' Perceptions Toward Incorporating And Expanding Telehealth Service Delivery Knowledge In Curricula And Future Practice: A Cross-Sectional Study, Kylie Watson, Nikhil M. Mardhekar, Utkarsh Pandey, Julia Wells, Karen Gruszynski, Amanda H. Wilkerson, John J. Dascanio, Syed S. Quadri, Jonathan T. Leo, Krishen D. Samuel, Vinayak K. Nahar, Robert E. Davis

Student Publications

Objective: Telehealth is the use of technology to deliver medical services. Potential uses among veterinarians include consulting with specialists about complicated cases, sending in electronic prescriptions, or meeting with clients to discuss patient health. Although the coronavirus disease 2019 pandemic posed many challenges to the veterinary profession, it accelerated the adoption of telehealth among veterinarians. As many of these changes took place quickly in response to the pandemic, many of those in practice did not receive much training or guidance; therefore, this study explores veterinary students' perceptions regarding incorporating telehealth into the veterinary curriculum and the utilization of telehealth in …

A Rare Case Of Primary Squamous Cell Carcinoma Of The Stomach: A Case Report, Abby Kunitsky, Gautam Maddineni, Julia Janecki, Edward Jurkovic, Vladimir Ferrer

Student Publications

Pure primary gastric squamous cell carcinoma (PGSCC) is a notably rare gastric malignancy. We present the case of a 51-year-old woman with advanced gastric squamous cell carcinoma characterized by a 7.6 cm necrotic mass invading the proximal stomach, liver metastasis, and lymphadenopathy at diagnosis. Despite the lack of standardized treatment protocols, we review tumor markers and potential management strategies, including surgical and chemotherapeutic interventions. The rarity and aggressive nature of PGSCC necessitates further research to develop effective detection and treatment methods to improve patient prognosis and survival outcomes.

Sirt1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction By Promoting Mitochondrial Bioenergetics, Zunhui Du, Yanting Zhou, Qiheng Li, Yuan Xie, Tingfang Zhu, Jing Qiao, Ruihong Zhang, Yangyang Bao, Lingjie Wang, Yinyin Xie, Jinwei Quan, Menglu Lin, Ning Zhang, Qi Jin, Wenbin Liang, Liqun Wu, Tong Yin, Yucai Xie

Student Publications

Dilated cardiomyopathy (DCM) is associated with high mortality despite advanced therapies. The LMNA gene encodes lamin A/C and is the second most frequently mutated gene associated with DCM, for which therapeutic options are limited. Here we generated Lmna–/– mice and found they exhibited cardiac dysfunction at the age of 1 month but not at 2 weeks. Proteomics showed down-regulation of mitochondrial function–related pathways in Lmna–/– hearts. Moreover, early injured mitochondria with decreased cristae density and sirtuin 1 (SIRT1) down-regulation were observed in 2-week-old Lmna–/– hearts. Adenoviral overexpression of SIRT1 in lamin A/C knockdown neonatal rat ventricular myocytes …

Trust In Physicians Among Young Sexual Minority Men, Yifan Lai, Madeline Cohodes, Marybec Griffin, Tejossy John, Benjamin Grin, Perry N. Halkitis, Jessica Jaiswal

Faculty Publications

Trust in physicians and the medical establishment more broadly is critical for access to and provision of relevant healthcare services. This is especially true for sexual minority men (SMM) as their healthcare is negatively impacted due to stigma and discrimination which in turn affects disclosure of sexual behavior and sexual orientation. This study sought to understand trust in physicians (TIP) as it relates to anal sex position, difficulty in paying for healthcare, insurance status, and pre-exposure prophylaxis (PrEP) use. This study employs data from a cross-sectional survey conducted between February 2018 and February 2019. The final analytic sample is 179 …

Monkeypox Presenting As Periorbital Cellulitis: A Case Report, Unaiza Batool, Fahad S. Siddiqui, Jessika Sanz, Shoaib Siddiqui

GME Publications

Monkeypox, a viral disease caused by the monkeypox virus is well known for its characteristic rash with macular, papular, and vesicular stages. Although the skin is one of the most affected organs by monkeypox, the virus can also impact the respiratory, ophthalmologic, genitourinary, and gastrointestinal systems, among others. It is extremely common for the disease to begin with flu-like symptoms in the prodromal phase before cutaneous manifestations emerge. Here, we describe a unique case of monkeypox infection in which a patient first presented with periorbital cellulitis before any characteristic skin findings appeared. The source of the infection was unknown and …