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Feasibility Of Electronic Medication Monitoring Among Adolescents And Emerging Adults With Sickle Cell Disease, Aimee Hildenbrand, Katherine Kidwell, Meghan Mcgrady, Constance Mara, Charles Quinn, Lori Crosby Dec 2023

Feasibility Of Electronic Medication Monitoring Among Adolescents And Emerging Adults With Sickle Cell Disease, Aimee Hildenbrand, Katherine Kidwell, Meghan Mcgrady, Constance Mara, Charles Quinn, Lori Crosby

Department of Pediatrics Faculty Papers

Purpose: To examine the feasibility of using MEMS® bottles to assess adherence among adolescents and emerging adults with sickle cell disease.

Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS® bottle to store hydroxyurea (n = 14) or deferasirox (n = 4).

Results: One hundred percent initiated MEMS® use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS® use included medication changes and transition to adult care; facilitators included tip sheets and reminders.

Conclusion: While MEMS® is acceptable to …


Investigating Mems Devices In Flow Conditions Relevant To Flow-Through Systems., Mohammad Shafquatul Islam Dec 2023

Investigating Mems Devices In Flow Conditions Relevant To Flow-Through Systems., Mohammad Shafquatul Islam

Electronic Theses and Dissertations

Advancements in microscale actuating technologies has substantially expanded the possibilities of interacting with the surrounding environment. Microstructures that deflect in response to mechanical forces are one of the largest application areas of microelectromechanical systems (MEMS). MEMS devices, functioning as sensors, actuators, and support structures, find applications in inertial sensors, pressure sensors, chemical sensors, and robotics, among others. Driven by the critical role of catalytic membrane reactors, this dissertation aims to evaluate enzyme activity on polymeric membranes and explore how fabrication methods from the field of Electrical and Computer Engineering (ECE) can incorporate sensing and actuation into these porous surfaces. Toward …


Signal Classification Based On Analog Computing Using Mems Network, Mohammad Okour Jul 2023

Signal Classification Based On Analog Computing Using Mems Network, Mohammad Okour

Durham School of Architectural Engineering and Construction: Dissertations, Thesis, and Student Research

The rising complexity of machine learning algorithms and Artificial Intelligence in many applications, such as smart building, has prompted the development of alternate computing options. Because of their compact size, low power consumption, and diverse functionality, microelectromechanical systems (MEMS) have emerged as a possible candidate. This thesis focuses on using MEMS networks as computing units to classify a simple signal classification task using neural network methodology. The study intends to show the potential of using MEMS as an analog computing unit by discussing the advantage of the bi-stability pull-in behavior and hysteresis to create an accurate classifier of these waveforms. …


The Effect Of Heating Area And Wheatstone Bridge Materials On A Thermally Actuated Mems Viscosity Sensor, Connor Michael Levine Jul 2023

The Effect Of Heating Area And Wheatstone Bridge Materials On A Thermally Actuated Mems Viscosity Sensor, Connor Michael Levine

Theses

Being able to accurately measure oil viscosity in real time is critical for multiple applications. It can ensure that the oil being used to protect and lubricate gears and other mechanical elements is good. To do this a thermally actuated micro electromechanical systems (MEMS) based sensor has been previously developed. The sensor is able to measure viscosity by having the fluid couple with the oscillating diaphragm and monitoring the frequency, amplitude and quality factor of the waveform. To improve the accuracy of the sensor, 5 different versions were created to study the effects of heating area and the sensing material …


Modeling, Simulation And Control Of Microrobots For The Microfactory., Zhong Yang May 2023

Modeling, Simulation And Control Of Microrobots For The Microfactory., Zhong Yang

Electronic Theses and Dissertations

Future assembly technologies will involve higher levels of automation in order to satisfy increased microscale or nanoscale precision requirements. Traditionally, assembly using a top-down robotic approach has been well-studied and applied to the microelectronics and MEMS industries, but less so in nanotechnology. With the boom of nanotechnology since the 1990s, newly designed products with new materials, coatings, and nanoparticles are gradually entering everyone’s lives, while the industry has grown into a billion-dollar volume worldwide. Traditionally, nanotechnology products are assembled using bottom-up methods, such as self-assembly, rather than top-down robotic assembly. This is due to considerations of volume handling of large …


Planar Element Alignment System, Benjamin E. Lavigna, Benny F. Cruz, Samuel Gierhan, Jacob Q. Henriksen Mar 2023

Planar Element Alignment System, Benjamin E. Lavigna, Benny F. Cruz, Samuel Gierhan, Jacob Q. Henriksen

Mechanical Engineering

Precise alignment to the micron level is a necessity for microfluidic/micromechanical devices to function as designed. Because of this, a micro-alignment device was commissioned by Professor Hans Mayer on behalf of the Cal Poly Microfluidics Laboratory. Prototype creation was bounded by a set of requirements including, ability to align PDMS & Silicon wafer halves to ± 10 microns, total process speed of three minutes, and total budget of $3000. Some major design hurdles included an ability to verify alignment, possible non-planar alignment pieces, and an inability to contact any point on the face of the alignment pieces after bonding treatment. …


Modeling The Effects Of Radiation On Microelectromechanical Resonators, David D. Lynes Mar 2023

Modeling The Effects Of Radiation On Microelectromechanical Resonators, David D. Lynes

Theses and Dissertations

As the use of MEMS becomes more prolific in air, space, defense, and power applications, they will be exposed to more extreme radiation environments. This dissertation explores the effects of ionizing and nonionizing radiation on MEMS. AlN-on-Si based piezoelectric bulk acoustic wave resonators were irradiated by gamma-rays and silicon ions while measuring S-parameters in situ. Changes to the resonator and equivalent circuit parameters are extracted. The resonators demonstrated resilience against the effects of radiation-induced charge trapping. However, radiation-induced atomic displacements caused shifts to resonant frequency. From these data, an atomistic model is derived to describe the relationship between radiation type …


The Development Of Optomechanical Sensors—Integrating Diffractive Optical Structures For Enhanced Sensitivity, Faolan Radford Mcgovern, Aleksandra Hernik, Catherine M. Grogan, George Amarandei, Izabela Naydenova Jan 2023

The Development Of Optomechanical Sensors—Integrating Diffractive Optical Structures For Enhanced Sensitivity, Faolan Radford Mcgovern, Aleksandra Hernik, Catherine M. Grogan, George Amarandei, Izabela Naydenova

Conference Papers

The term optomechanical sensors describes devices based on coupling the optical and mechanical sensing principles. The presence of a target analyte leads to a mechanical change, which, in turn, determines an alteration in the light propagation. Having higher sensitivity in comparison with the individual technologies upon which they are based, the optomechanical devices are used in biosensing, humidity, temperature, and gases detection. This perspective focuses on a particular class, namely on devices based on diffractive optical structures (DOS). Many configurations have been developed, including cantilever- and MEMS-type devices, fiber Bragg grating sensors, and cavity optomechanical sensing devices. These state-of-the-art sensors …


Designing A Flexible Framework For Developing Acoustic Array Systems, Charles Fulton Gilliland Jan 2023

Designing A Flexible Framework For Developing Acoustic Array Systems, Charles Fulton Gilliland

Electronic Theses and Dissertations

In recent years, research conducted by the Applied Acoustics group at the NationalCenter for Physical Acoustics has involved the use of microphone arrays to study the propagation of sound through outdoor environments. In such research, there is need for data acquisition systems which can be reconfigured in both hardware and software. This work is an effort to develop a modular acoustic data acquisition framework which can be configured to accommodate a wide variety of acoustic array applications. In hardware, the framework provides modularity with a generic mainboard which uses a common interface to collect data from application-specific microphone boards. In …