Digital Commons Network^™

Sensitivity Analysis Of An Agent-Based Simulation Model Using Reconstructability Analysis, Andey M. Nunes, Martin Zwick, Wayne Wakeland

Systems Science Faculty Publications and Presentations

Reconstructability analysis, a methodology based on information theory and graph theory, was used to perform a sensitivity analysis of an agent-based model. The NetLogo BehaviorSpace tool was employed to do a full 2^k factorial parameter sweep on Uri Wilensky’s Wealth Distribution NetLogo model, to which a Gini-coefficient convergence condition was added. The analysis identified the most influential predictors (parameters and their interactions) of the Gini coefficient wealth inequality outcome. Implications of this type of analysis for building and testing agent-based simulation models are discussed.

A Conformation Variant Of P53 Combined With Machine Learning Identifies Alzheimer Disease In Preclinical And Prodromal Stages, Giulia Abate, Marika Vezzoli, Letizia Polito, Antonio Guaita, Diego Albani, Moira Marizzoni, Emirena Garrafa, Alessandra Marengoni, Gianluigi Forloni, Giovanni B. Frisoni, Jeffrey L. Cummings, Maurizio Memo, Daniela Uberti

School of Medicine Faculty Publications

© 2020 by the authors. Li-censee MDPI, Basel, Switzerland. Early diagnosis of Alzheimer’s disease (AD) is a crucial starting point in disease man-agement. Blood-based biomarkers could represent a considerable advantage in providing AD-risk information in primary care settings. Here, we report new data for a relatively unknown blood-based biomarker that holds promise for AD diagnosis. We evaluate a p53-misfolding conformation rec-ognized by the antibody 2D3A8, also named Unfolded p53 (U-p532D3A8+), in 375 plasma samples derived from InveCe.Ab and PharmaCog/E-ADNI longitudinal studies. A machine learning approach is used to combine U-p532D3A8+ plasma levels with Mini-Mental State Examination (MMSE) and apolipoprotein E …

Development Of The Algorithm For Supporting Decision-Making In Self-Government Bodies Using Machine Learning, X J. Raximboyev

Scientific-technical journal

The article deals with the problem of constructing a model and algorithm for decision support in self-government bodies using machine learning. The method of multiple linear regression for processing the training sample was chosen as a machine learning method. In the training sample, independent data consists of parametric estimates in numerical form of self-government bodies in three areas of activity, such as education, social environment and crime. And the dependent parameter consists of generalized expert assessments of self-government bodies, also in numerical form. The model and algorithm of the decision support process using the method of multiple linear regression are …

A Study On An Accurate Underwater Location Of Hybrid Underwater Gliders Using Machine Learning, Sang-Ki Jeong, Hyeung-Sik Choi, Dea-Hyung Ji, Mai The Vu, Joon-Young Kim, Sung Min Hong, Hyun Joon Cho

Journal of Marine Science and Technology

A hybrid underwater glider (HUG) is marine observation equipment that consumes a small amount of energy and offers greater range and navigation times. To achieve reduced energy consumption, however, the HUG uses imprecise navigation sensors, such as mems-type GPS and AHRS, resulting in inaccurate coordination. This study makes a new attempt on the application of machine learning algorithms in a way that complements sensor data errors to improve navigation performance. The proposed algorithm was used to a simulation of the HUG’s navigation and control system, after which the updated heading angle was decided by using the previous position data and …

The Machines Aren’T Taking Over (Yet): An Empirical Comparison Of Traditional, Profiling, And Machine Learning Approaches To Criterion-Related Validation, Kristin S. Allen, Mathijs Affourtit, Craig M. Reddock

Personnel Assessment and Decisions

Criterion-related validation (CRV) studies are used to demonstrate the effectiveness of selection procedures. However, traditional CRV studies require significant investment of time and resources, as well as large sample sizes, which often create practical challenges. New techniques, which use machine learning to develop classification models from limited amounts of data, have emerged as a more efficient alternative. This study empirically investigates the effectiveness of traditional CRV with a variety of profiling approaches and machine learning techniques using repeated cross-validation. Results show that the traditional approach generally performs best both in terms of predicting performance and larger group differences between candidates …

Forecasting Bitcoin Prices Using N-Beats Deep Learning Architecture, Alikhan Bulatov

Student Theses

The use of computationally intensive systems that employ machine learning algorithms is increasingly common in the field of finance. New state of the art deep learning architectures for time series forecasting are being developed each year making them more accurate than ever. This study evaluates the predictive power of the N-BEATS deep learning architecture trained on Bitcoin daily, hourly, and up-to-the-minute data in comparison with other popular time series forecasting methods such as LSTM and ARIMA. Prediction errors are measured with Mean Average Percentage Error (MAPE), and Root Mean Squared Error (RMSE). The results suggest that the developed N-BEATS model …

Pathway‐Extended Gene Expression Signatures Integrate Novel Biomarkers That Improve Predictions Of Patient Responses To Kinase Inhibitors, Ashis Bagchee‐Clark, Eliseos J. Mucaki, Tyson Whitehead, Peter Rogan

Biochemistry Publications

Cancer chemotherapy responses have been related to multiple pharmacogenetic biomarkers, often for the same drug. This study utilizes machine learning to derive multi‐gene expression signatures that predict individual patient responses to specific tyrosine kinase inhibitors, including erlotinib, gefitinib, sorafenib, sunitinib, lapatinib and imatinib. Support vector machine (SVM) learning was used to train mathematical models that distinguished sensitivity from resistance to these drugs using a novel systems biology‐based approach. This began with expression of genes previously implicated in specific drug responses, then expanded to evaluate genes whose products were related through biochemical pathways and interactions. Optimal pathway‐extended SVMs predicted responses in …

Technology Criticism And Data Literacy: The Case For An Augmented Understanding Of Media Literacy, Thomas Knaus

Journal of Media Literacy Education

Reviewing the history of media literacy education might help us to identify how creating media as an approach can contribute to fostering knowledge, understanding technical issues, and to establishing a critical attitude towards technology and data. In a society where digital devices and services are omnipresent and decisions are increasingly based on data, critical analysis must penetrate beyond the “outer shell” of machines – their interfaces – through the technology itself, and the data, and algorithms, which make these devices and services function. Because technology and data constitute the basis of all communication and collaboration, media literate individuals …

Metarec: Meta-Learning Meets Recommendation Systems, James Le

Theses

Artificial neural networks (ANNs) have recently received increasing attention as powerful modeling tools to improve the performance of recommendation systems. Meta-learning, on the other hand, is a paradigm that has re-surged in popularity within the broader machine learning community over the past several years. In this thesis, we will explore the intersection of these two domains and work on developing methods for integrating meta-learning to design more accurate and flexible recommendation systems.

In the present work, we propose a meta-learning framework for the design of collaborative filtering methods in recommendation systems, drawing from ideas, models, and solutions from modern approaches …

An Assessment Of The Hydrological Trends Using Synergistic Approaches Of Remote Sensing And Model Evaluations Over Global Arid And Semi-Arid Regions, Wenzhao Li, Hesham El-Askary, Rejoice Thomas, Surya Prakash Tiwari, Karuppasamy Manikandan, Thomas Piechota, Daniele Struppa

Mathematics, Physics, and Computer Science Faculty Articles and Research

Drylands cover about 40% of the world’s land area and support two billion people, most of them living in developing countries that are at risk due to land degradation. Over the last few decades, there has been warming, with an escalation of drought and rapid population growth. This will further intensify the risk of desertification, which will seriously affect the local ecological environment, food security and people’s lives. The goal of this research is to analyze the hydrological and land cover characteristics and variability over global arid and semi-arid regions over the last decade (2010–2019) using an integrative approach of …

An Investigation Of Grammar Gender-Bias Correction For Google Translate When Translating From English To French, Ahmed Samy Merah

Student Theses

This work investigated how to address the Google Translate's gender-bias when translating from English to French. The developed solution is called GT gender-bias corrector that was built based on combining natural language processing and machine learning methods. The natural language processing was used to analyze the original sentences and their translations grammatically identifying parts of speech. The parts of speech analysis facilitated the identification of three patterns that are associated with the gender bias of Google Translate when translating from English to French. The three patterns were labeled simple, intermediate and complex to reflect the structure complexity. Samples of texts …

Using Machine Learning To Regulate Intensity Of Immersion Therapy Treatment Of Phobias Through Vital Feedback, Mark Beauchamp

Student Theses

The treatment of acrophobia has been trying to keep up with newer technology with the incorporation of virtual reality for exposure therapy, but that approach still lacks automation and still leaves a good portion for human error. The proposed method introduced in this paper is that a machine learning model could replace the need for continuous human intervention. With a few different models of bridges and buildings and the ability for a machine learning model to dynamically alter the height of these building we could theoretically put the patient in the exact situation that will maximize the efficiency of their …

Diagnostic Utility Of Genome-Wide Dna Methylation Analysis In Mendelian Neurodevelopmental Disorders, Sadegheh Haghshenas, Pratibha Bhai, Erfan Aref-Eshghi, Bekim Sadikovic

Paediatrics Publications

Mendelian neurodevelopmental disorders customarily present with complex and overlapping symptoms, complicating the clinical diagnosis. Individuals with a growing number of the so-called rare disorders exhibit unique, disorder-specific DNA methylation patterns, consequent to the underlying gene defects. Besides providing insights to the pathophysiology and molecular biology of these disorders, we can use these epigenetic patterns as functional biomarkers for the screening and diagnosis of these conditions. This review summarizes our current understanding of DNA methylation episignatures in rare disorders and describes the underlying technology and analytical approaches. We discuss the computational parameters, including statistical and machine learning methods, used for the …

Fire Code Violation Detection, Salim Elewa

Student Theses

his paper explores the creation of an object detection system for mobile using YOLO(You Only Look Once) algorithm., a real-time object detection model that is developed to run on a portable device such as a cellphone that does not have a Graphics Processing Unit (GPU). This algorithm is utilized to detect fire code violations, specifically the obstructed door in a fire separation: the areas surround- ing the door opening shall be kept clear of anything that would be likely to ob- struct. The machine learning algorithm utilized has been fine-tuned to fit the model based on accuracy levels. The author …

Data-Driven Assessment Of Site Responses At Liquefiable Sites, Weiwei Zhan

All Dissertations

Soil liquefaction is a process that saturated soils lose stiffness and strength due to the generation of pore water pressure under rapid earthquake loading and behave like a liquid. Earthquake-induced liquefaction could generate two interrelated hazards on liquefiable sites (belonging to NEHRP F class): excessive ground deformations and unfavorable ground motions. Liquefaction can significantly modify the surface ground motions through changing the material properties of subsurface soils, and the modified ground motions can affect the seismic response of the liquefied soils. Moreover, the site response on liquefiable sites may change from non-liquefied to liquefied response, and be subjected to environmental …

Detecting Hacker Threats: Performance Of Word And Sentence Embedding Models In Identifying Hacker Communications, Susan Mckeever, Brian Keegan, Andrei Quieroz

Conference papers

Abstract—Cyber security is striving to find new forms of protection against hacker attacks. An emerging approach nowadays is the investigation of security-related messages exchanged on deep/dark web and even surface web channels. This approach can be supported by the use of supervised machine learning models and text mining techniques. In our work, we compare a variety of machine learning algorithms, text representations and dimension reduction approaches for the detection accuracies of software-vulnerability-related communications. Given the imbalanced nature of the three public datasets used, we investigate appropriate sampling approaches to boost detection accuracies of our models. In addition, we examine how …

Language-Driven Region Pointer Advancement For Controllable Image Captioning, Annika Lindh, Robert J. Ross, John D. Kelleher

Conference papers

Controllable Image Captioning is a recent sub-field in the multi-modal task of Image Captioning wherein constraints are placed on which regions in an image should be described in the generated natural language caption. This puts a stronger focus on producing more detailed descriptions, and opens the door for more end-user control over results. A vital component of the Controllable Image Captioning architecture is the mechanism that decides the timing of attending to each region through the advancement of a region pointer. In this paper, we propose a novel method for predicting the timing of region pointer advancement by treating the …

Unifying Chemistry And Machine Learning For The Study Of Noncovalent Interactions, Jacob A. Townsend

Doctoral Dissertations

Gas separations are in great demand for carbon emission reduction, natural gas purification, oxygen isolation, and much more. Many of these separations rely on cost-prohibitive methods such as cryogenic distillation or strong-binding solvents. As a result, novel materials are being developed to subvert the energetic expense of gas separation processes. These studies focus on improving the performance of alternative materials, including (but not limited to) metal-organic frameworks, covalent organic frameworks, dense polymeric membranes, porous polymers, and ionic liquids.

In this work, the atomistic effects of functional units are explored for gas separations processes using electronic structure theory and machine learning. …

In The Margins: Reconsidering The Range And Contribution Of Diazotrophs In Nearshore Environments, Corday R. Selden

OES Theses and Dissertations

Dinitrogen (N₂) fixation enables primary production and, consequently, carbon dioxide drawdown in nitrogen (N) limited marine systems, exerting a powerful influence over the coupled carbon and N cycles. Our understanding of the environmental factors regulating its distribution and magnitude are largely based on the range and sensitivity of one genus, Trichodesmium. However, recent work suggests that the niche preferences of distinct diazotrophic (N₂ fixing) clades differ due to their metabolic and ecological diversity, hampering efforts to close the N budget and model N₂ fixation accurately. Here, I explore the range of N₂ fixation …

Using Machine Learning Software In The Human Resource Recruiting Process For Candidates From Dubai Police Academy, Ibrahim Alkhazraji, Ali Saeed Buhaliba

Theses

Since Machine learning software explored the first recruitment software and found that utilizing technology improves their efficiency at work, speed, and makes the process easier, the use of machine learning for recruitment has become one of the major themes in human resources. In a few years, hiring top talents may lean entirely on the ability of the recruiters to automate their workflows intelligently. Over time, the function of human resource management has indeed evolved in organizations, as technology has been marveled for its greater efficiency in almost every sector. The use of Machine learning for recruiting in organizations has not …

Algorithmic Opacity, Private Accountability, And Corporate Social Disclosure In The Age Of Artificial Intelligence, Sylvia Lu

Vanderbilt Journal of Entertainment & Technology Law

Today, firms develop machine-learning algorithms to control human decisions in nearly every industry, creating a structural tension between commercial opacity and democratic transparency. In many of their commercial applications, advanced algorithms are technically complicated and privately owned, which allows them to hide from legal regimes and prevents public scrutiny. However, they may demonstrate their negative effects—erosion of democratic norms, damages to financial gains, and extending harms to stakeholders—without warning. Nevertheless, because the inner workings and applications of algorithms are generally incomprehensible and protected as trade secrets, they can be completely shielded from public surveillance. One of the solutions to this …

Facial Image Analysis Using Ratio-Fusion-Score Based Approach To Support Forensic Investigation, Deepak Waikar

Manipal Journal of Science and Technology

In recent years, the face recognition field has attained high performance in the identification of a person. Facial recognition algorithms should be able to perform even in the case of similar faces such as Look-alikes or identical twins. Twin identification becomes an important task in face recognition as twins are involved in pursuing criminal activities. The proposed framework focuses on the recognition of individual faces, and Look-alikes by finding distinctiveness of different facial features in the face by using multi-parametric anthropometry measurements. Fusion score is generated by considering the fusion of facial ratios such as image ratio and golden ratio …

Machine-Learning-Based Hybrid Method For The Multilevel Fast Multipole Algorithm, Jia Jing Sun, Sheng Sun, Yongpin P. Chen, Lijun Jiang, Jun Hu

Electrical and Computer Engineering Faculty Research & Creative Works

In this letter, a hybrid translation computation method for the multilevel fast multipole algorithm (MLFMA) is proposed based on machine learning. The hybrid method combines both generalized regression neural network (GRNN) and artificial neural network (ANN) to replace the traditional translation procedure during the solving process of the MLFMA. Based on the data corresponding to every one of the interaction list boxes at each level, the hybrid neural network is trained. Comparing with the previous machine learning method in this field, the proposed model is more general, and with lower complexity since it inherits the accuracy of the GRNN as …

Price Prediction And Valuation Using Data Mining In Dubai Real Estate Market, Abdulla Alhathboor

Theses

The purpose of this study is to find out the impact of data mining in predicting prices and values of real estate units in the Dubai real estate market. This market has always been one of the biggest markets in the economy of any nation worldwide and has always been considered one of the biggest indicators on the health of any economy. After the devastating crash of the world economy in 2008, many real estate projects were halted and economies are still recovering from that incident. Real estate brokers and agents found it difficult to sell any property during that …

Walls Have Ears: Eavesdropping User Behaviors Via Graphics-Interrupt-Based Side Channel, Haoyu Ma, Jianwen Tian, Debin Gao, Jia Chunfu

Research Collection School Of Computing and Information Systems

Graphics Processing Units (GPUs) are now playing a vital role in many devices and systems including computing devices, data centers, and clouds, making them the next target of side-channel attacks. Unlike those targeting CPUs, existing side-channel attacks on GPUs exploited vulnerabilities exposed by application interfaces like OpenGL and CUDA, which can be easily mitigated with software patches. In this paper, we investigate the lower-level and native interface between GPUs and CPUs, i.e., the graphics interrupts, and evaluate the side channel they expose. Being an intrinsic profile in the communication between a GPU and a CPU, the pattern of graphics interrupts …

Machine Learning Prediction Of Shear Capacity Of Steel Fiber Reinforced Concrete, Wassim Ben Chaabene

Electronic Thesis and Dissertation Repository

The use of steel fibers for concrete reinforcement has been growing in recent years owing to the improved shear strength and post-cracking toughness imparted by fiber inclusion. Yet, there is still lack of design provisions for steel fiber-reinforced concrete (SFRC) in building codes. This is mainly due to the complex shear transfer mechanism in SFRC. Existing empirical equations for SFRC shear strength have been developed with relatively limited data examples, making their accuracy restricted to specific ranges. To overcome this drawback, the present study suggests novel machine learning models based on artificial neural network (ANN) and genetic programming (GP) to …

New Methods For Deep Learning Based Real-Valued Inter-Residue Distance Prediction, Jacob Barger

Theses

Background: Much of the recent success in protein structure prediction has been a result of accurate protein contact prediction--a binary classification problem. Dozens of methods, built from various types of machine learning and deep learning algorithms, have been published over the last two decades for predicting contacts. Recently, many groups, including Google DeepMind, have demonstrated that reformulating the problem as a multi-class classification problem is a more promising direction to pursue. As an alternative approach, we recently proposed real-valued distance predictions, formulating the problem as a regression problem. The nuances of protein 3D structures make this formulation appropriate, allowing predictions …

Pathway-Extended Gene Expression Signatures Integrate Novel Biomarkers That Improve Predictions Of Patient Responses To Kinase Inhibitors, Ashis Jem Bagchee-Clark, Eliseos J. Mucaki, Tyson Whitehead, Peter Rogan

Biochemistry Publications

No abstract provided.

Pathway-Extended Gene Expression Signatures Integrate Novel Biomarkers That Improve Predictions Of Patient Responses To Kinase Inhibitors, Jem Bagchee-Clark, Eliseos J. Mucaki, Tyson Whitehead, Peter Rogan

Biochemistry Publications

Cancer chemotherapy responses have been related to multiple pharmacogenetic biomarkers, often for the same drug. This study utilizes machine learning to derive multi-gene expression signatures that predict individual patient responses to specific tyrosine kinase inhibitors, including erlotinib, gefitinib, sorafenib, sunitinib, lapatinib and imatinib. Support Vector Machine learning was used to train mathematical models that distinguished sensitivity from resistance to these drugs using a novel systems biology-based approach. This began with expression of genes previously implicated in specific drug responses, then expanded to evaluate genes whose products were related through biochemical pathways and interactions. Optimal pathway-extended support vector machines predicted responses …

Prediction Of Mental Illness In Heart Disease Patients: Association Of Comorbidities, Dietary Supplements, And Antibiotics As Risk Factors, Jayanth Sivakumar, Saba Ahmed, Lina Begdache, Swati Jain, Daehan Won

Health & Wellness Studies Faculty Scholarship

Comorbidities, dietary supplement use, and prescription drug use may negatively (or positively) affect mental health in cardiovascular patients. Although the significance of mental illnesses, such as depression, anxiety, and schizophrenia, on cardiovascular disease is well documented, mental illnesses resulting from heart disease are not well studied. In this paper, we introduce the risk factors of mental illnesses as an exploratory study and develop a prediction framework for mental illness that uses comorbidities, dietary supplements, and drug usage in heart disease patients. Particularly, the data used in this study consist of the records of 68,647 patients with heart disease, including the …