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Assessing The Effectiveness Of Antiretroviral Adherence Interventions: Using Marginal Structural Models To Replicate The Findings Of Randomized Controlled Trials., Maya L. Petersen, Yue Wang, Mark J. Van Der Laan, David R. Bangsberg
Assessing The Effectiveness Of Antiretroviral Adherence Interventions: Using Marginal Structural Models To Replicate The Findings Of Randomized Controlled Trials., Maya L. Petersen, Yue Wang, Mark J. Van Der Laan, David R. Bangsberg
Maya Petersen
Randomized controlled trials of interventions to improve adherence to antiretroviral medications are not always feasible. Marginal Structural Models (MSM) are a statistical methodology that aims to replicate the findings of randomized controlled trials using observational data. Under the assumption of no unmeasured confounders, three MSM estimators are available to estimate the causal effect of an intervention. Two of these estimators, G-computation and Inverse Probability of Treatment Weighted, can be implemented using standard software. G-computation relies on fitting a multivariable regression of adherence on the intervention and confounders. Thus, it is related to the standard multivariable regression approach to estimating causal …
The Relationship Between Health Beliefs And Adherence To Treatment Of Russian Immigrants With Hypertension, Michael R. Kolesnikov
The Relationship Between Health Beliefs And Adherence To Treatment Of Russian Immigrants With Hypertension, Michael R. Kolesnikov
Master's Projects
Introduction: Hypertension (HTN) has been identified as a common health problem in every ethnic group in the USA. Due to the silent nature of the HTN, some cultures may not perceive this condition as being serious or potentially fatal. Objective: The purpose of this study was to investigate the health beliefs of Russian-speaking immigrants with hypertension and their adherence to the prescribed treatment. Design: The study was a non-experimental exploratory survey and interview. Convenience sampling was used. The Health Belief Model (HBM) provided the theoretical framework. Sample: A total of 62 subjects (27% male and 73% female, ages from 51 …
Shiga Toxin Of Enterohemorrhagic Escherichia Coli Type O157:H7 Promotes Intestinal Colonization, Cory M. Robinson, James F. Sinclair, Michael J. Smith, Alison D. O'Brien
Shiga Toxin Of Enterohemorrhagic Escherichia Coli Type O157:H7 Promotes Intestinal Colonization, Cory M. Robinson, James F. Sinclair, Michael J. Smith, Alison D. O'Brien
Uniformed Services University of the Health Sciences
Enterohemorrhagic Escherichia coli (EHEC) 0157:H7 is a food-borne pathogen that can cause bloody diarrhea and, occasionally, acute renal failure as a consequence of Shiga toxin (Stx) production by the organism. Stxs are potent cytotoxins that are lethal to animals at low doses. Thus, Stxs not only harm the host but, as reported here, also significantly enhance the capacity of EHEC O157:H7 to adhere to epithelial cells and to colonize the intestines of mice. Tissue culture experiments showed that this toxin-mediated increase in bacterial adherence correlated with an Stx-evoked increase in a eukaryotic receptor for the EHEC O157:H7 attachment factor intimin.
Motivation, Psychological Distress And Exercise Adherence Following Myocardial Infarction, Angela Ljubic, Frank P. Deane, Robert Zecchin, Richard Denniss
Motivation, Psychological Distress And Exercise Adherence Following Myocardial Infarction, Angela Ljubic, Frank P. Deane, Robert Zecchin, Richard Denniss
Faculty of Health and Behavioural Sciences - Papers (Archive)
Fifty patients with myocardial infarction were recruited from a hospital based Cardiac Education and Assessment Program (CEAP) in Sydney, Australia. The Exercise Motivation Inventory-2 (EMI-2) and the Depression, Anxiety and Stress Scale (DASS) were administered prior to commencement in the program and re-administered by telephone interview at 5-month followup. Four exercise adherence measures were completed: attendance, exercise stress test, self-report ratings and a 7-day activity recall interview. There was a 46% adherence rate for MI patients during the hospital based CEAP. Of those individuals who completed CEAP, 91% obtained functional improvement on the exercise stress test. For the 38 patients …