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An Implantable Low Pressure, Low Drift, Dual Biopressure Sensor And In-Vivo Calibration Methods Thereof, Chad Eric Seaver Dec 2018

An Implantable Low Pressure, Low Drift, Dual Biopressure Sensor And In-Vivo Calibration Methods Thereof, Chad Eric Seaver

Doctoral Dissertations

The human body’s intracranial pressure (ICP) is a critical component in sustaining healthy blood flow to the brain while allowing adequate volume for brain tissue within the rigid structures of the cranium. Disruptions in the body’s autoregulation of intracranial pressure are often caused by hemorrhage, tumors, edema, or excess cerebral spinal fluid resulting in treatments that are estimated to globally cost up to approximately five billion dollars annually. A critical element in the contemporary management of acute head injury, intracranial hemorrhage, stroke, or other conditions resulting in intracranial hypertension, is the real-time monitoring of ICP. Currently, such mainstream clinical monitoring …


Exploration Of Radiation Damage Mechanism In Mems Devices., Pranoy Deb Shuvra Dec 2018

Exploration Of Radiation Damage Mechanism In Mems Devices., Pranoy Deb Shuvra

Electronic Theses and Dissertations

We explored UV, X-ray and proton radiation damage mechanisms in MEMS resonators. T-shaped MEMS resonators of different dimensions were used to investigate the effect of radiation. Radiation damage is observed in the form of resistance and resonance frequency shift of the device. The resistance change indicates a change in free carrier concentration and mobility, while the resonance frequency change indicates a change in mass and/or elastic constant. For 255nm UV radiation, we observed a persistent photoconductivity that lasts for about 60 hours after radiation is turned off. The resonance frequency also decreases 40-90 ppm during irradiation and slowly recovers at …


In Situ Investigation Of Thermally Activated Processes Using Mems-Based Devices: Practical Challenges & Applications, Sriram Vijayan Nov 2018

In Situ Investigation Of Thermally Activated Processes Using Mems-Based Devices: Practical Challenges & Applications, Sriram Vijayan

Doctoral Dissertations

In situ heating holders offer the possibility of studying thermally activated processes by performing real time, high temperature experiments inside the transmission electron microscope. The poor thermal stability of traditional furnace-type heating holders limits their use to a narrow range of materials and processes. Modern micro electro mechanical system (MEMS) based heating holders have significantly improved the ability to perform such experiments and have led to a revival in the field of in situ TEM. The excellent thermal stability of the MEMS devices allows us to carry out controlled heating and cooling experiments on both particulate and bulk samples at …


Fabrication And Characterization Of A Magnetohydrodynamic Micropump From Polydimethylsiloxane (Pdms), Rachel K. Weber Aug 2018

Fabrication And Characterization Of A Magnetohydrodynamic Micropump From Polydimethylsiloxane (Pdms), Rachel K. Weber

Graduate Theses - Chemical Engineering

Microfluidics is a growing area of study in recent years, particularly for lab-on-a-chip applications. Fluids must oftentimes be transported from one location on the chip to another. This study focuses on the fabrication and characterization of a magnetohydrodynamic micropump. The device was fabricated in the Rose-Hulman Institute of Technology MiNDS facility, and consisted of a PDMS channel and titanium electrodes supported on a glass slide with a permanent magnet. An Arduino microcontroller capable of pulse width modulation (PWM) was used to control the electrical potential. An electrode design that spanned the full length of the channel was successful in driving …


Iridium Oxide (Iro2) As A Top Electrode For Ferroelectric Micro-Electro-Mechanical Systems (Mems) Devices For Radiation Rich Environments, Manuel Rivas May 2018

Iridium Oxide (Iro2) As A Top Electrode For Ferroelectric Micro-Electro-Mechanical Systems (Mems) Devices For Radiation Rich Environments, Manuel Rivas

Doctoral Dissertations

The multifunctional properties of ferroelectric materials make them ideal components for numerous applications including for extreme environments such as space. Iridium oxide (IrO2) electrodes have been demonstrated to improve the lifetime of ferroelectric memory devices, however little is known about its influence on the electromechanical properties important for ferroelectric microelectromechanical systems (MEMS). The performance of thin film lead zirconate titanate (PZT) based MEMS is affected by the processing conditions, composition, device design, electrode materials, and the environment. This work details the development and characterization of iridium oxide electrodes for PZT based microelectromechanical and pyroelectric-harvesting systems, fabrication induced defects, and design …


Development Of Microdialysis Probes In Series Approach Toward Eliminating Microdialysis Sampling Calibration: Miniaturization Into A Pdms Microfluidic Device, Randy Espinal Cabrera May 2018

Development Of Microdialysis Probes In Series Approach Toward Eliminating Microdialysis Sampling Calibration: Miniaturization Into A Pdms Microfluidic Device, Randy Espinal Cabrera

Graduate Theses and Dissertations

A new microdialysis sampling method and microfluidic device were developed in vitro. The method consisted of using up to four microdialysis sampling probes connected in series to evaluate the relative recovery (RR) of different model solutes methyl orange, fluorescein isothiocyanate (FITC)-dextran average mol. wt. 4,000 (FITC-4), FITC-10, FITC-20, and FITC-40. Different flow rates (0.8, 1.0, and 1.5 µL/min) were used to compare experimentally observed relative recoveries with theoretical estimations. With increasing the number of probes in series, the relative recovery increases and ~100% (99.7% ± 0.9%) relative recovery for methyl orange was obtained. For larger molecules such as fluorescein isothiocyanate …


Nanoscale Mapping Of In-Situ Micro Electro Mechanical Systems With Atomic Force Microscopy, Manuel Rivas Feb 2018

Nanoscale Mapping Of In-Situ Micro Electro Mechanical Systems With Atomic Force Microscopy, Manuel Rivas

Master's Theses

Micro-electro-mechanical-systems (MEMS) are increasingly at our fingertips. To understand and thereby improve their performance, especially given their ever-decreasing sizes, it is crucial to measure their functionality in-situ. Atomic Force Microscopy (AFM) is well suited for such studies, allowing nanoscale lateral and vertical resolution of static displacements, as well as mapping of the dynamic response of these physically actuating microsystems. In this work, the vibration of a tuning fork based viscosity sensor is mapped and compared to model experiments in air, liquid, and a curing collagen gel. The switching response of a MEMS switch with nanosecond time-scale activation is also monitored …


Design And Evaluation Of Novel Attitude Estimation System Using Mems Sensors For Indoor Uas, Joshua Bruce Milam Jan 2018

Design And Evaluation Of Novel Attitude Estimation System Using Mems Sensors For Indoor Uas, Joshua Bruce Milam

Graduate Theses, Dissertations, and Problem Reports

Most small unmanned aerial systems in use today, employ extended Kalman filter sensor fusion algorithms in order to provide accurate estimations of attitude or orientation. These complex algorithms use measurements from GPS receivers and magnetometer sensors that can be rendered useless in GPS denied environments or areas of significant magnetic interference, such as inside buildings or other structures. The complexity of these algorithms makes them inaccessible for some researchers and hobbyists who wish to code their own attitude estimation algorithms. This complexity is also computationally expensive and requires processors that are powerful enough to operate the algorithms along with any …