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Articles 61 - 63 of 63
Full-Text Articles in Entire DC Network
Ionic Liquids And Gumbos For Biomedical And Sensing Applications, Paul Kipkorir Sang Magut
Ionic Liquids And Gumbos For Biomedical And Sensing Applications, Paul Kipkorir Sang Magut
LSU Doctoral Dissertations
This dissertation is a synopsis of advancements in the field of ionic liquids and a group of uniform materials based on organic salts (GUMBOS) in biomedical applications, especially with regard to cancer research. The toxicity of chemotherapeutic agents to normal tissues and drug resistance are a major concern in cancer treatment. In this dissertation, GUMBOS and nanoGUMBOS as well as ionic liquids and nanodroplets are explored as possible chemotherapeutic agents with minimal toxicity to normal cells. In the first part of my dissertation, exploitation of ionic liquid chemistry to modulate toxicity of rhodamine 6G is reported. Rhodamine 6G-based GUMBOS with …
Social Support In Young Adult Cancer Survivors And Their Close Social Network Members, Nicholas Thomas Iannarino
Social Support In Young Adult Cancer Survivors And Their Close Social Network Members, Nicholas Thomas Iannarino
Theses and Dissertations--Communication
A cancer diagnosis often causes biographical disruption in the lives of young adult (i.e., 18-39; YA) survivors and their close social network members (i.e., familial, plutonic, or romantic relational partners with whom the survivor has a salient relationship; SNM). In order to integrate their illness into their lives, normatively regain balance and equilibrium, and achieve a “new normal” following a cancer diagnosis, YA survivors and their close SNMs must work to reconstruct their biographies by engaging in tangible interpersonal communication processes often used to initiate and maintain relationships. However, YA cancer survivors report facing social struggles due to the biographical …
The Effect Of Lactic Acid On Mast Cell Function, Andrew J. Spence
The Effect Of Lactic Acid On Mast Cell Function, Andrew J. Spence
Theses and Dissertations
This study shows for the first time the effect that L-(+)-lactic acid has on mast cell activation. Lactic acid is a byproduct of anaerobic glycolysis and is associated with inflammatory environments such as wounds, tumors and, asthma. In this study, pre-treatment with lactic acid altered cytokine production by bone marrow-derived mast cells (BMMC). Specifically, lactic acid enhanced cytokine secretion following IgE cross-linking, but decreased IL-33 mediated cytokine production. These effects were altered by genetic background, since C57BL/6 mast cells demonstrated the aforementioned result, but lactic acid had no effect on IgE-mediated cytokine production in 129/SvJ mast cells. The affected cytokines …