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Resource Modelling For The Qc Laboratory At Xyz Pharmaceuticals In Southern Africa, Ngonidzashe Portia Munhuweyi, Z Ekeocha, S Byrn, K Clase Nov 2021

Resource Modelling For The Qc Laboratory At Xyz Pharmaceuticals In Southern Africa, Ngonidzashe Portia Munhuweyi, Z Ekeocha, S Byrn, K Clase

BIRS Africa Technical Report Papers

Quality control (QC) laboratories are critical components in drug manufacturing and running them efficiently contributes to better, consistent supply of cost-effective quality products, while also and preventing deaths due to untimely delivery or unavailability of medicines. Having a resource modelling tool to estimate resources needed to handle a particular demand in a given system is essential for efficient running of QC laboratory. This study was done to establish such a model at XYZ Pharmaceuticals. The list of all products manufactured by XYZ Pharmaceuticals Southern Africa was reviewed; and product families for all products were identified. Analysts’ hands on time (HOT) …


Assessing The Impact Of The Lead/Lag Times On The Project Duration Estimates In Highway Construction, Mohamed Abdel-Raheem, Jennifer Reyes, Xiaohui Wang, Grecia Silva Sanchez Jul 2021

Assessing The Impact Of The Lead/Lag Times On The Project Duration Estimates In Highway Construction, Mohamed Abdel-Raheem, Jennifer Reyes, Xiaohui Wang, Grecia Silva Sanchez

Civil Engineering Faculty Publications and Presentations

The literature mentions multiple factors that can affect the accuracy of estimating the project duration in highway construction, such as weather, location, and soil conditions. However, there are other factors that have not been explored, yet they can have significant impact on the accuracy of the project time estimate. Recently, TxDOT raised a concern regarding the importance of the proper estimating of the lead/lag times in project schedules. These lead/lag times are often determined based on the engineer’s experience. However, inaccurate estimates of the lead/lag time can result in unrealistic project durations. In order to investigate this claim, the study …


Limousine Service Management: Capacity Planning With Predictive Analytics And Optimization, Peng Liu, Ying Chen, Chung-Piaw Teo Jul 2021

Limousine Service Management: Capacity Planning With Predictive Analytics And Optimization, Peng Liu, Ying Chen, Chung-Piaw Teo

Research Collection Lee Kong Chian School Of Business

The limousine service in luxury hotels is an integral component of the whole customer journey in the hospitality industry. One of the largest hotels in Singapore manages a fleet of both in-house and outsourced vehicles around the clock, serving 9,000 trips per month on average. The need for vehicles may scale up rapidly, especially during special events and festive periods in the country. The excess demand is met by having additional outsourced vehicles on standby, incurring millions of dollars of additional expenses per year for the hotel. Determining the required number of limousines by hour of the day is a …


A Matheuristic Algorithm For The Vehicle Routing Problem With Cross-Docking, Aldy Gunawan, Audrey Tedja Widjaja, Pieter Vansteenwegen, Vincent F. Yu May 2021

A Matheuristic Algorithm For The Vehicle Routing Problem With Cross-Docking, Aldy Gunawan, Audrey Tedja Widjaja, Pieter Vansteenwegen, Vincent F. Yu

Research Collection School Of Computing and Information Systems

This paper studies the integration of the vehicle routing problem with cross-docking (VRPCD). The aim is to find a set of routes to deliver products from a set of suppliers to a set of customers through a cross-dock facility, such that the operational and transportation costs are minimized, without violating the vehicle capacity and time horizon constraints. A two-phase matheuristic based on column generation is proposed. The first phase focuses on generating a set of feasible candidate routes in both pickup and delivery processes by implementing an adaptive large neighborhood search algorithm. A set of destroy and repair operators are …