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A Role For Ct In Covid-19? What Data Really Tell Us So Far, Md Hope, Ca Raptis, A Shah, Mm Hammer, Ts Henry Jan 2020

A Role For Ct In Covid-19? What Data Really Tell Us So Far, Md Hope, Ca Raptis, A Shah, Mm Hammer, Ts Henry

Journal Articles

No abstract provided.


Study Of Alteplase For Respiratory Failure In Sars-Cov2/Covid-19: Study Design Of The Phase Iia Stars Trial., H. B. Moore, C. D. Barrett, E. E. Moore, R. Jhunjhnuwala, R. C. Mcintyre, P. K. Moore, J. Wang, N. Hajizadeh, A. Sauaia, M. B. Yaffe, +1 Additional Author Jan 2020

Study Of Alteplase For Respiratory Failure In Sars-Cov2/Covid-19: Study Design Of The Phase Iia Stars Trial., H. B. Moore, C. D. Barrett, E. E. Moore, R. Jhunjhnuwala, R. C. Mcintyre, P. K. Moore, J. Wang, N. Hajizadeh, A. Sauaia, M. B. Yaffe, +1 Additional Author

Journal Articles

Background:The COVID-19 pandemic has caused a large surge of acute respiratory distress syndrome (ARDS). Prior phase I trials (non COVID-19) demonstrated improvement in pulmonary function in ARDS patients using fibrinolytic therapy. A follow-up trial using the widely available tissue-plasminogen activator (alteplase) is now needed to assess optimal dosing and safety in this critically ill patient population. Objective:To describe the design and rationale of a Phase IIa trial to evaluate the safety and efficacy of alteplase treatment for moderate/severe COVID-19-induced ARDS. Patients/Methods:A rapidly adaptive, pragmatic, open label, randomized, controlled, phase IIa clinical trial will be conducted with three groups: intravenous(IV) alteplase …


Teaching Professional Formation In Response To The Covid-19 Pandemic., L. B. Mccullough, J. Coverdale, F. A. Chervenak Jan 2020

Teaching Professional Formation In Response To The Covid-19 Pandemic., L. B. Mccullough, J. Coverdale, F. A. Chervenak

Journal Articles

In response to the COVID-19 pandemic, the Association of American Medical Colleges has called for a temporary suspension of clinical teaching activities for medical students. Planning for the continued involvement of learners in patient care during this pandemic should include teaching learners professional formation. The authors provide an ethical framework to guide such teaching, based on the ethical principle of beneficence and the professional virtues of courage and self-sacrifice from professional ethics in medicine. The authors show that these concepts support the conclusion that learners are ethically obligated to accept reasonable, but not unreasonable, risk. Based on this ethical framework, …


Universal Testing For Coronavirus Disease 2019 In Pregnant Women Admitted For Delivery: Prevalence Of Peripartum Infection And Rate Of Asymptomatic Carriers At Four New York Hospitals Within An Integrated Healthcare System., M. J. Blitz, B. Rochelson, A. C. Rausch, R. Solmonovich, W. Shan, A. Combs, M. Nimaroff Jan 2020

Universal Testing For Coronavirus Disease 2019 In Pregnant Women Admitted For Delivery: Prevalence Of Peripartum Infection And Rate Of Asymptomatic Carriers At Four New York Hospitals Within An Integrated Healthcare System., M. J. Blitz, B. Rochelson, A. C. Rausch, R. Solmonovich, W. Shan, A. Combs, M. Nimaroff

Journal Articles

No abstract provided.


We May Develop Medications Effective Against Covid-19, But Can We Distribute Them Equitably?, D. J. Kersten, A. N. Makaryus Jan 2020

We May Develop Medications Effective Against Covid-19, But Can We Distribute Them Equitably?, D. J. Kersten, A. N. Makaryus

Journal Articles

No abstract provided.


What Gi Physicians Need To Know During Covid-19 Pandemic, P. J. Thuluvath, J. J. Alukal, N. Ravindran, S. K. Satapathy Jan 2020

What Gi Physicians Need To Know During Covid-19 Pandemic, P. J. Thuluvath, J. J. Alukal, N. Ravindran, S. K. Satapathy

Journal Articles

No abstract provided.


Initial Impact Of Coronavirus Disease 2019 (Covid-19) On Radiology Practices: An Acr/Rbma Survey., A. Malhotra, X. Wu, H. B. Fleishon, R. Duszak, E. Silva, G. B. Mcginty, C. Bender, B. Williams, J. J. Naidich, P. C. Sanelli, +3 Additional Authors Jan 2020

Initial Impact Of Coronavirus Disease 2019 (Covid-19) On Radiology Practices: An Acr/Rbma Survey., A. Malhotra, X. Wu, H. B. Fleishon, R. Duszak, E. Silva, G. B. Mcginty, C. Bender, B. Williams, J. J. Naidich, P. C. Sanelli, +3 Additional Authors

Journal Articles

PURPOSE:The coronavirus disease 2019 (COVID-19) pandemic affected radiology practices in many ways. The aim of this survey was to estimate declines in imaging volumes and financial impact across different practice settings during April 2020. METHODS:The survey, comprising 48 questions, was conducted among members of the ACR and the Radiology Business Management Association during May 2020. Survey questions focused on practice demographics, volumes, financials, personnel and Northwell Health adjustments, and anticipation of recovery. RESULTS:During April 2020, nearly all radiology practices reported substantial (56.4%-63.7%) declines in imaging volumes, with outpatient imaging volumes most severely affected. Mean gross charges declined by 50.1% to …


Institutional Preparedness Strategies For Heart Failure, Durable Left Ventricular Assist Device, And Heart Transplant Patients During The Coronavirus Disease 2019 (Covid-19) Pandemic, A. Bansal, D. Goldstein, S. Schettle, S. Pepitone, B. Lima, D. T. Pham, J. Cowger, A. Schubert, S. P. Pinney Jan 2020

Institutional Preparedness Strategies For Heart Failure, Durable Left Ventricular Assist Device, And Heart Transplant Patients During The Coronavirus Disease 2019 (Covid-19) Pandemic, A. Bansal, D. Goldstein, S. Schettle, S. Pepitone, B. Lima, D. T. Pham, J. Cowger, A. Schubert, S. P. Pinney

Journal Articles

No abstract provided.


Outcomes In Patients With Severe Covid-19 Disease Treated With Tocilizumab: A Case-Controlled Study, G. Rojas-Marte, M. Khalid, O. Mukhtar, A. T. Hashmi, M. A. Waheed, S. Ehrlich, A. Aslam, S. Siddiqui, C. Agarwal, J. Shani, +8 Additional Authors Jan 2020

Outcomes In Patients With Severe Covid-19 Disease Treated With Tocilizumab: A Case-Controlled Study, G. Rojas-Marte, M. Khalid, O. Mukhtar, A. T. Hashmi, M. A. Waheed, S. Ehrlich, A. Aslam, S. Siddiqui, C. Agarwal, J. Shani, +8 Additional Authors

Journal Articles

© The Author(s) 2020. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For permissions, please email: journals.permissions@oup.com. BACKGROUND: COVID-19 is an ongoing threat to society. Patients who develop the most severe forms of the disease have high mortality. The interleukin-6 inhibitor tocilizumab has the potential to improve outcomes in these patients by preventing the development of cytokine release storm. AIMS: To evaluate the outcomes of patients with severe COVID-19 disease treated with the interleukin-6 inhibitor tocilizumab. METHODS: We conducted a retrospective, case-control, single-center study in patients with severe to critical COVID-19 disease treated …


Prevalence Of Chronic Liver Disease In Patients With Covid-19 And Their Clinical Outcomes: A Systematic Review And Meta-Analysis, A. J. Kovalic, S. K. Satapathy, P. J. Thuluvath Jan 2020

Prevalence Of Chronic Liver Disease In Patients With Covid-19 And Their Clinical Outcomes: A Systematic Review And Meta-Analysis, A. J. Kovalic, S. K. Satapathy, P. J. Thuluvath

Journal Articles

No abstract provided.


Physiologic Response To Angiotensin Ii Treatment For Coronavirus Disease 2019-Induced Vasodilatory Shock: A Retrospective Matched Cohort Study., D. E. Leisman, F. Mastroianni, G. Fisler, S. Shah, Z. Hasan, M. Narasimhan, M. D. Taylor, C. S. Deutschman Jan 2020

Physiologic Response To Angiotensin Ii Treatment For Coronavirus Disease 2019-Induced Vasodilatory Shock: A Retrospective Matched Cohort Study., D. E. Leisman, F. Mastroianni, G. Fisler, S. Shah, Z. Hasan, M. Narasimhan, M. D. Taylor, C. S. Deutschman

Journal Articles

Objectives:To assess the early physiologic response to angiotensin-II treatment in patients with coronavirus disease 2019-induced respiratory failure and distributive shock. Design:Retrospective consecutive-sample cohort study. Setting:Three medical ICUs in New York during the coronavirus disease 2019 outbreak. Patients:All patients were admitted to the ICU with respiratory failure and were receiving norepinephrine for distributive shock. Interventions:The treatment groups were patients who received greater than or equal to 1 hour of angiotensin-II treatment. Time-zero was the time of angiotensin-II initiation. Controls were identified using a 2:1 hierarchical process that matched for 1) date and unit of admission; 2) specific organ support modalities; 3) …


Race/Ethnicity And Spatiotemporal Trends In Sars-Cov-2 Prevalence On Obstetrical Units In New York., M. J. Blitz, B. Rochelson, L. Prasannan, W. Shan, F. A. Chervenak, M. Nimaroff, E. Bornstein Jan 2020

Race/Ethnicity And Spatiotemporal Trends In Sars-Cov-2 Prevalence On Obstetrical Units In New York., M. J. Blitz, B. Rochelson, L. Prasannan, W. Shan, F. A. Chervenak, M. Nimaroff, E. Bornstein

Journal Articles

No abstract provided.


Response: From Cardiology To Covid The Impact Of A Pandemic On Fellowship Training, J. T. Kuvin Jan 2020

Response: From Cardiology To Covid The Impact Of A Pandemic On Fellowship Training, J. T. Kuvin

Journal Articles

No abstract provided.


Role Of A Pediatric Cardiologist In The Covid-19 Pandemic, T. Niaz, K. Hope, M. Fremed, N. Misra, C. Altman, J. Glickstein, J. Sanchez-De-Toledo, A. Fraisse, J. Miller, D. Chowdhury, +2 Additional Authors Jan 2020

Role Of A Pediatric Cardiologist In The Covid-19 Pandemic, T. Niaz, K. Hope, M. Fremed, N. Misra, C. Altman, J. Glickstein, J. Sanchez-De-Toledo, A. Fraisse, J. Miller, D. Chowdhury, +2 Additional Authors

Journal Articles

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. Coronavirus disease 2019 (COVID-19) has affected patients across all age groups, with a wide range of illness severity from asymptomatic carriers to severe multi-organ dysfunction and death. Although early reports have shown that younger age groups experience less severe disease than older adults, our understanding of this phenomenon is in continuous evolution. Recently, a severe multisystem inflammatory syndrome in children (MIS-C), with active or recent COVID-19 infection, has been increasingly reported. Children with MIS-C may demonstrate signs and symptoms of Kawasaki disease, but also have some distinct differences. These children …


Sarcoma European And Latin American Network (Selnet) Recommendations On Prioritization In Sarcoma Care During The Covid-19 Pandemic, J. Martin-Broto, N. Hindi, S. Aguiar, R. Badilla-Gonzalez, V. Castro-Oliden, M. Chacon, R. Correa-Generoso, E. De Alava, R. Maki, J. Blay, +25 Additional Authors Jan 2020

Sarcoma European And Latin American Network (Selnet) Recommendations On Prioritization In Sarcoma Care During The Covid-19 Pandemic, J. Martin-Broto, N. Hindi, S. Aguiar, R. Badilla-Gonzalez, V. Castro-Oliden, M. Chacon, R. Correa-Generoso, E. De Alava, R. Maki, J. Blay, +25 Additional Authors

Journal Articles

No abstract provided.


Seizure And Covid-19: Association And Review Of Potential Mechanism., R. Joseph, N. Narula, A. Daouk, N. Katyal, S. Acharya, A. Avula, R. Maroun Jan 2020

Seizure And Covid-19: Association And Review Of Potential Mechanism., R. Joseph, N. Narula, A. Daouk, N. Katyal, S. Acharya, A. Avula, R. Maroun

Journal Articles

Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, this highly transmissible virus has since spread rapidly around the world. Though respiratory complication is the primarily reported manifestation though rare, yet serious neurological complications are being frequently reported in the literature. In selected coronavirus disease-2019 (COVID-19) cases neurologic complications may manifest as seizures. In this paper, we have reviewed current literature on seizures linked with SARS- COV 2 infection including published or pre-print original articles, review articles, and case reports. We have discussed the electroencephalogram (EEG), imaging, and Cerebrospinal fluid (CSF) findings in COVID-19 patients …


Locked-In With Covid-19, A. Avula, A. Gill, R. Nassar, K. Nalleballe, S. Siddamreddy, M. Chalhoub Jan 2020

Locked-In With Covid-19, A. Avula, A. Gill, R. Nassar, K. Nalleballe, S. Siddamreddy, M. Chalhoub

Journal Articles

© 2020 Elsevier Ltd Coronavirus Disease 2019 (COVID-19) can be associated with various neurological manifestations including acute strokes. Hyper acute diagnosis and treatment are key factors which decrease mortality and morbidity in stroke patients. The COVID-19 pandemic has introduced a great strain on the healthcare system, and as a result clinicians are facing several barriers in diagnosing and treating strokes. Delayed presentation of strokes is a problem as some in the general population defer the decision to seek immediate medical attention fearing contracting the virus. Also playing a role is the paucity of healthcare professionals available during a pandemic. Recent …


Management Of Pancreatic Cancer During Covid-19 Pandemic: To Treat Or Not To Treat?, R. Patel, M. W. Saif Jan 2020

Management Of Pancreatic Cancer During Covid-19 Pandemic: To Treat Or Not To Treat?, R. Patel, M. W. Saif

Journal Articles

Pancreatic cancer is a very aggressive disease and survival remains dismal even with treatment. Currently, management of patients with pancreatic cancer has been complicated by the ongoing COVID-19 pandemic. Medical oncologists face the dilemma of whether to treat or to not treat these patients who are at high-risk of complications and even death from COVID-19. No current guidelines are available and our limited experience at this time makes it more difficult to manage these patients. Although we have general strategies available from experience in Italy, we need more treatment specific strategies to help mitigate risks of complications and toxicities from …


Diabetes Is Associated With Increased Risk For In-Hospital Mortality In Patients With Covid-19: A Systematic Review And Meta-Analysis Comprising 18,506 Patients, L. Palaiodimos, N. Chamorro-Pareja, D. Karamanis, W. Li, P. D. Zavras, K. M. Chang, P. Mathias, D. G. Kokkinidis Jan 2020

Diabetes Is Associated With Increased Risk For In-Hospital Mortality In Patients With Covid-19: A Systematic Review And Meta-Analysis Comprising 18,506 Patients, L. Palaiodimos, N. Chamorro-Pareja, D. Karamanis, W. Li, P. D. Zavras, K. M. Chang, P. Mathias, D. G. Kokkinidis

Journal Articles

© 2020, Hellenic Endocrine Society. Purpose: Infectious diseases are more frequent and can be associated with worse outcomes in patients with diabetes. The aim of this study was to systematically review and conduct a meta-analysis of the available observational studies reporting the effect of diabetes on mortality among hospitalized patients with COVID-19. Methods: The Medline, Embase, Google Scholar, and medRxiv databases were reviewed for identification of eligible studies. A random effects model meta-analysis was used, and I2 was utilized to assess the heterogeneity. In-hospital mortality was defined as the endpoint. Sensitivity, subgroup, and meta-regression analyses were performed. Results: A total …


Neuromuscular Complications With Sars-Cov-2 Infection: A Review, N. Katyal, N. Narula, S. Acharya, R. Govindarajan Jan 2020

Neuromuscular Complications With Sars-Cov-2 Infection: A Review, N. Katyal, N. Narula, S. Acharya, R. Govindarajan

Journal Articles

© Copyright © 2020 Katyal, Narula, Acharya and Govindarajan. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases were first reported in Wuhan, Hubei province of China in December, 2019. SARS- COV-2 primarily affects the cardio-respiratory system. Over the last few months, several studies have described various neurological sequelae of SARS-COV-2 infection. Neurological complications are more frequent in patients with severe respiratory infections. In this review, we have analyzed the current literature on neuromuscular complications associated with SARS-COV-2 and highlighted possible mechanisms of neuromuscular invasion. We reviewed 11 studies describing 11 cases of Guillain Barre syndrome (GBS), and 1 case each …


Initial Impact Of Covid-19 On Radiology Practices: An Acr/Rbma Survey, A. Malhotra, X. Wu, H. B. Fleishon, R. Duszak, E. Silva, G. B. Mcginty, C. Bender, B. Williams, J. J. Naidich, P. C. Sanelli, +3 Additional Authors Jan 2020

Initial Impact Of Covid-19 On Radiology Practices: An Acr/Rbma Survey, A. Malhotra, X. Wu, H. B. Fleishon, R. Duszak, E. Silva, G. B. Mcginty, C. Bender, B. Williams, J. J. Naidich, P. C. Sanelli, +3 Additional Authors

Journal Articles

© 2020 American College of Radiology Purpose: The coronavirus disease 2019 (COVID-19) pandemic affected radiology practices in many ways. The aim of this survey was to estimate declines in imaging volumes and financial impact across different practice settings during April 2020. Methods: The survey, comprising 48 questions, was conducted among members of the ACR and the Radiology Business Management Association during May 2020. Survey questions focused on practice demographics, volumes, financials, personnel and Northwell Health adjustments, and anticipation of recovery. Results: During April 2020, nearly all radiology practices reported substantial (56.4%-63.7%) declines in imaging volumes, with outpatient imaging volumes most …


Nebulized In-Line Endotracheal Dornase Alfa And Albuterol Administered To Mechanically Ventilated Covid-19 Patients: A Case Series., A. G. Weber, A. S. Chau, M. Egeblad, B. J. Barnes, T. Janowitz Jan 2020

Nebulized In-Line Endotracheal Dornase Alfa And Albuterol Administered To Mechanically Ventilated Covid-19 Patients: A Case Series., A. G. Weber, A. S. Chau, M. Egeblad, B. J. Barnes, T. Janowitz

Journal Articles

Background Mechanically ventilated patients with coronavirus disease 2019 (COVID-19) have a mortality of 24-53%, in part due to distal mucopurulent secretions interfering with ventilation. Dornase alfa is recombinant human DNase 1 and digests DNA in mucoid sputum. Nebulized dornase alfa is FDA-approved for cystic fibrosis treatment. DNA from neutrophil extracellular traps (NETs) contributes to the viscosity of mucopurulent secretions. NETs are found in the serum of patients with severe COVID-19, and targeting NETs reduces mortality in animal models of acute respiratory distress syndrome (ARDS). Thus, dornase alfa may be beneficial to patients with severe COVID-19, acting as a mucolytic and …


The Hola Covid-19 Study: An International Effort To Determine How Covid-19 Has Impacted Oncology Practices In Latin America, C. Bernabe-Ramirez, A. I. Velazquez, C. Olazagasti, C. D. Bergerot, P. G. Bergerot, E. Soto-Perez-De-Celis, N. Duma Jan 2020

The Hola Covid-19 Study: An International Effort To Determine How Covid-19 Has Impacted Oncology Practices In Latin America, C. Bernabe-Ramirez, A. I. Velazquez, C. Olazagasti, C. D. Bergerot, P. G. Bergerot, E. Soto-Perez-De-Celis, N. Duma

Journal Articles

© 2020 Countries in Latin America and the Caribbean have become hotspots of the novel coronavirus (COVID-19) pandemic, exacerbating socioeconomic inequalities and overwhelming fragmented health systems. Studies from the United States and Europe have highlighted the disproportionate effects of COVID-19 on patients with cancer and the disruption it has caused on cancer care delivery. The HOLA COVID-19 Study aims to understand how cancer care in Latin American countries has been affected by the COVID-19 pandemic.


Behavioral Changes Without Respiratory Symptoms As A Presenting Sign Of Covid-19 Encephalitis., T. Rebeiz, K. Lim-Hing, S. Khazanehdari, K. Rebeiz Jan 2020

Behavioral Changes Without Respiratory Symptoms As A Presenting Sign Of Covid-19 Encephalitis., T. Rebeiz, K. Lim-Hing, S. Khazanehdari, K. Rebeiz

Journal Articles

The clinical presentation, diagnosis, and treatment of coronavirus disease 2019 (COVID-19) encephalitis are still being characterized. Few case reports describing COVID-19 encephalitis are available in the literature. We present a case of COVID-19 encephalitis who presented with behavioral disturbances without respiratory symptoms.


Applying Triage Principles Of Mass Casualty Events To The Sars-Cov-2 Pandemic: From The Perspective Of The Acute Care Surgeons At Long Island Jewish Medical Center In The Covid Epicenter Of The United States., M Giangola, S Siskind, B Faliks, R Dela Cruz, A Lee, M Shebes, G Ritter, J Prince, G Coppa, R Barrera, V Patel Jan 2020

Applying Triage Principles Of Mass Casualty Events To The Sars-Cov-2 Pandemic: From The Perspective Of The Acute Care Surgeons At Long Island Jewish Medical Center In The Covid Epicenter Of The United States., M Giangola, S Siskind, B Faliks, R Dela Cruz, A Lee, M Shebes, G Ritter, J Prince, G Coppa, R Barrera, V Patel

Journal Articles

No abstract provided.


Central Apnea In An Adolescent With Covid-19, S Enner, S Hormozdyaran, R Varughese, J Milillo, I Pavkovic, E Laureta, J Schneider, S Kothare Jan 2020

Central Apnea In An Adolescent With Covid-19, S Enner, S Hormozdyaran, R Varughese, J Milillo, I Pavkovic, E Laureta, J Schneider, S Kothare

Journal Articles

No abstract provided.


Coronavirus Disease 2019 (Covid-19) Presenting As Purulent Fulminant Myopericarditis And Cardiac Tamponade: A Case Report And Literature Review., A Khatri, F Wallach Jan 2020

Coronavirus Disease 2019 (Covid-19) Presenting As Purulent Fulminant Myopericarditis And Cardiac Tamponade: A Case Report And Literature Review., A Khatri, F Wallach

Journal Articles

No abstract provided.


Covid-19 And Neurosurgical Practice: An Interim Report, S Amin-Hanjani, Nc Bambakidis, Fg Barker, Bs Carter, Km Cockroft, R Du, Jf Fraser, Mg Hamilton, M Schulder, G Zada, +9 Additional Authors Jan 2020

Covid-19 And Neurosurgical Practice: An Interim Report, S Amin-Hanjani, Nc Bambakidis, Fg Barker, Bs Carter, Km Cockroft, R Du, Jf Fraser, Mg Hamilton, M Schulder, G Zada, +9 Additional Authors

Journal Articles

No abstract provided.


Covid-19 Impact On Well-Being And Education In Radiology Residencies: A Survey Of The Association Of Program Directors In Radiology, Jb Robbins, E England, Md Patel, Cm Debenedectis, Ds Sarkany, De Heitkamp, Jm Milburn, V Kalia, K Ali, Sg Jordan, +4 Additional Authors Jan 2020

Covid-19 Impact On Well-Being And Education In Radiology Residencies: A Survey Of The Association Of Program Directors In Radiology, Jb Robbins, E England, Md Patel, Cm Debenedectis, Ds Sarkany, De Heitkamp, Jm Milburn, V Kalia, K Ali, Sg Jordan, +4 Additional Authors

Journal Articles

No abstract provided.


Covid-19 In Recent Heart Transplant Recipients: Clinicopathologic Features And Early Outcomes, B. Lima, G. Gibson, S Vullaganti, K. Malhame, S Maybaum, St Hussain, S Shah, Dt Majure, F Wallach, K Jang, V Bijol, Mj Esposito, Ak Williamson, Rm Thomas, Ta Bhuiya, Ha Fernandez, Gr Stevens Jan 2020

Covid-19 In Recent Heart Transplant Recipients: Clinicopathologic Features And Early Outcomes, B. Lima, G. Gibson, S Vullaganti, K. Malhame, S Maybaum, St Hussain, S Shah, Dt Majure, F Wallach, K Jang, V Bijol, Mj Esposito, Ak Williamson, Rm Thomas, Ta Bhuiya, Ha Fernandez, Gr Stevens

Journal Articles

No abstract provided.