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Oct-Based Elastography For Large And Small Deformations, Donald D. Duncan, Sean J. Kirkpatrick, Ruikang K. Wang Nov 2006

Oct-Based Elastography For Large And Small Deformations, Donald D. Duncan, Sean J. Kirkpatrick, Ruikang K. Wang

Electrical and Computer Engineering Faculty Publications and Presentations

We present two approaches to speckle tracking for optical coherence tomography (OCT)-based elastography, one appropriate for small speckle motions and the other for large, rapid speckle motions. Both approaches have certain advantages over traditional cross-correlation based motion algorithms. We apply our algorithms to quantifying the strain response of a mechanically inhomogeneous, bi-layered polyvinyl alcohol tissue phantom that is subjected to either small or large dynamic compressive forces while being imaged with a spectral domain OCT system. In both the small and large deformation scenarios, the algorithms performed well, clearly identifying the two mechanically disparate regions of the phantom. The stiffness …


Imaging The Mechanical Stiffness Of Skin Lesions By In Vivo Acousto-Optical Elastography, Sean J. Kirkpatrick, Donald D. Duncan, Ruikang K. Wang, Molly Kulesz-Martin, Ken Lee Oct 2006

Imaging The Mechanical Stiffness Of Skin Lesions By In Vivo Acousto-Optical Elastography, Sean J. Kirkpatrick, Donald D. Duncan, Ruikang K. Wang, Molly Kulesz-Martin, Ken Lee

Electrical and Computer Engineering Faculty Publications and Presentations

Optical elastography is an imaging modality that relies on variations in the local mechanical properties of biological tissues as the contrast mechanism for image formation. Skin lesions, such as melanomas and other invasive conditions, are known to alter the arrangement of collagen fibers in the skin and thus should lead to alterations in local skin mechanical properties. We report on an acousto-optical elastography (AOE) imaging modality for quantifying the mechanical behavior of skin lesions. The method relies upon stimulating the tissue with a low frequency acoustic force and imaging the resulting strains in the tissue by means of quantifying the …


Thermal Imaging To Recover A Defect In Three Dimensional Objects, Breanne Baker Jul 2006

Thermal Imaging To Recover A Defect In Three Dimensional Objects, Breanne Baker

Mathematical Sciences Technical Reports (MSTR)

This paper focuses on the inverse problem of identifying an internal void in a bounded two- or three-dimensional region. Information, in form of a heat flux and temperature, is assumed to be obtainable only on the external boundary of the region. The reciprocity gap approach with a suitable test functions is used in both the two- and three-dimensional cases.


Non-Destructive Recovery Of Voids Within A Three Dimensional Domain Using Thermal Imaging, Victor B. Oyeyemi Jul 2006

Non-Destructive Recovery Of Voids Within A Three Dimensional Domain Using Thermal Imaging, Victor B. Oyeyemi

Mathematical Sciences Technical Reports (MSTR)

We develop an algorithm capable of detecting the presence of spherical voids in a thermally conducting object. In addition, the process recovers both the radii and locations of each void. Our method involves the application of a known steady state heat flux to the object's boundary and measurement of the induced steady state temperature on the boundary.