Digital Commons Network^™

Spt5 Affects The Rate Of Mrna Degradation And Physically Interacts With Ccr4 But Does Not Control Mrna Deadenylation, Yajun Cui, Yueh-Chin Chiang, Palaniswamy Viswanathan, Darren J. Lee, Clyde L. Denis

New Hampshire Agricultural Experiment Station Publications

The CCR4-NOT complex has been shown to have multiple roles in mRNA metabolism, including that of transcriptional elongation, mRNA transport, and nuclear exosome function, but the primary function of CCR4 and CAF1 is in the deadenylation and degradation of cytoplasmic mRNA. As previous genetic analysis supported an interaction between SPT5, known to be involved in transcriptional elongation, and that of CCR4, the physical association of SPT5 with CCR4 was examined. A two-hybrid screen utilizing the deadenylase domain of CCR4 as a bait identified SPT5 as a potential interacting protein. SPT5 at its physiological concentration was shown to immunoprecipitate CCR4 and …

Nh 2012 Primary Election Poll 12/25/2011, Unh Survey Center

All UNH Survey Center Polls

Election: NH Primary 2012

Students Save More Than $12,000 In 2011 Energy Challenge, Erika Mantz

Media Relations

No abstract provided.

U.S. Extended Continental Shelf Cruise To Map Sections Of The Mariana Trench And The Eastern And Southern Insular Margins Of Guam And The Northern Mariana Islands, Andy Armstrong

Center for Coastal and Ocean Mapping

U.S. Extended Continental Shelf Cruise to Map Sections of the Mariana Trench and the Eastern and Southern Insular Margins of Guam and the Northern Mariana Islands

CCOM-JHC CRUISE SU10-02

Leg 2: September 24 to October 21, 2010

Apra Harbor, Guam to Apra Harbor, Guam

Unh Hires Head Of Corporate Relations To Strengthen Partnerships With State's Businesses, Erika Mantz

Media Relations

No abstract provided.

Unh Faculty Ranked Among The Nation's Best Researchers, Erika Mantz

Media Relations

No abstract provided.

Unh Students Raise More Than $4,000 For Pease Greeters Scholarship Fund, Lori Wright

Media Relations

No abstract provided.

University Of New Hampshire Transfer Admissions Information Session Jan. 12, 2012, Jody Record

Media Relations

No abstract provided.

Part Ed 306 Minimum Standards For Public School Approval, New Hampshire Department Of Education

Manchester Research Group

New Hampshire minimum school standards.

Businesses Invited To Team Up With Unh Information Systems Students, Lori Wright

Media Relations

No abstract provided.

An Anti-Coagulation Agent Futhan Preferentially Targets Gaba(A) Receptors In Lungepithelia: Implication In Treating Asthma, Xuanmao Chen, Minghua Li, Zhi-Gang Xiong, Beverley A. Orser, John F. Macdonald, Wei-Yang Lu

Molecular, Cellular & Biomedical Sciences

Futhan is a serine protease inhibitor and medicine in the treatment of disseminated intravascular coagulation (DIC) and acute pancreatitis. It is metabolized quickly in vivo. Here we show that Futhan reversibly inhibits NMDA receptors in hippocampal neurons and GABAA receptors both in hippocampal neurons and in A549 cells, a human alveolar epithelial cell line. The effect of Futhan on GABAA receptors in A549 cells is much more potent than its effect on GABAA receptors in hippocampal neurons (IC50: 0.9 µM v.s. 7.3 µM). Since GABAA receptors are also expressed in various non-neuronal tissues, particularly in airway epithelia and GABA promotes …

Unwanted Online Sexual Exposures Decline For Youth, New Unh Research Finds Improving Online Environment May Be Result Of Greater Public Awareness, Lori Wright

Media Relations

No abstract provided.

"Button Up N.H." Weatherization Workshops To Be Held Throughout State, David Sims

Media Relations

No abstract provided.

N.H. Voters Have Become Less Republican Since 1960s, New Carsey Institute Research Shows, Lori Wright

Media Relations

No abstract provided.

Changes In New Hampshire’S Republican Party: Evolving Footprint In Presidential Politics, 1960-2008, Dante J. Scala

The Carsey School of Public Policy at the Scholars' Repository

This brief describes a series of dramatic changes in New Hampshire's political landscape over the past four decades. Examining presidential elections from 1960 to 2008, author Dante Scala uncovers a series of significant shifts in New Hampshire's political geography at the county level. He reports that historically Republican counties Grafton and Merrimack have both tilted Democratic consistently in recent decades and that New Hampshire has become less Republican overall. All of these changes have impacted not just general elections in New Hampshire, but the Republican presidential primary as well.

Dogs Help University Of New Hampshire Students Relieve Stress, Jody Record

Media Relations

No abstract provided.

Brief Of The Intellectual Property Amicus Brief Clinic Of The University Of New Hampshire School Of Law As Amicus Curiae In Support Of Neither Party, Susan M. Richey, John M. Greabe, Keith M. Harrison, J. Jeffrey Hawley

Law Faculty Scholarship

Amicus brief filed by the Intellectual Property Amicus Brief Clinic of the University of New Hampshire School of Law with the United States Court Of Appeals For The Ninth Circuit regarding United States v. Xavier Alvarez, Docket No. 11-210

Unh Launches Graduate Certificate In Special Education Administration To Address Critical Shortage In State, Lori Wright

Media Relations

No abstract provided.

Carsey Institute: Private Health Insurance Coverage Rates For Children Continue To Decline As Families Struggle With Recession, Lori Wright

Media Relations

No abstract provided.

Rates Of Public Health Insurance Coverage For Children Rise As Rates Of Private Coverage Decline, Michael J. Staley, Jessica A. Bean, Jessica D. Ulrich

The Carsey School of Public Policy at the Scholars' Repository

This brief uses data from the 2008, 2009, and 2010 American Community Survey to document changes in rates of children’s health insurance, between private and public. The authors report that, nationally, private health insurance for children decreased by just under 2 percentage points, while public health insurance increased by nearly 3 percentage points. Rural places and central cities witnessed significant declines in rates of private health insurance for children in nearly every region. Rates of public insurance coverage rose in every region and place type. Children’s health insurance coverage overall continued to rise in 2010, increasing by 0.6 of a …

Understanding' Of Climate Change Depends On Politics, New Carsey Institute Research Shows Views Of New Hampshire Residents Largely Mirror National Patterns, Lori Wright

Media Relations

No abstract provided.

Do You Believe The Climate Is Changing? Answers From New Survey Research, Lawrence C. Hamilton

The Carsey School of Public Policy at the Scholars' Repository

This brief explores how political views influence Americans’ understanding and perception of science. The research is based on a national version of the Community and Environment in Rural America survey called NCERA, and on New Hampshire’s statewide Granite State Poll. Author Lawrence Hamilton reports that most people on both surveys feel that they understand either a great deal or a moderate amount about global warming or climate change. However, deep partisan divisions affect both personal beliefs about climate change and perceptions of agreement among scientists. Democrats are much more likely to state they believe that climate change is happening, caused …

Unh Professor Offers Holiday Tipping Advice During The Economic Downturn, Lori Wright

Media Relations

No abstract provided.

Concerns About Teen Sexting Overblown, According To New Unh Research, Lori Wright

Media Relations

No abstract provided.

Youth Internet Safety Study (Yiss): Methodology Report., Kimberly J. Mitchell, Lisa M. Jones

Crimes Against Children Research Center

The Youth Internet Safety Surveys (YISS‐1, YISS‐2, and YISS‐3) were conducted in order to quantify and detail youth experiences with unwanted or problematic Internet experiences including sexual solicitations, harassment, and unwanted exposure to pornography on the Internet. YISS‐3 collected additional information about youth produced sexual images (YPSI) or “sexting.” The YISS‐1, YISS‐2 and YISS‐3 studies were conducted in 2000, 2005 and 2010, respectively, providing important comparative information on changes in the numbers of youth reporting unwanted or problematic Internet experiences at 5‐year intervals since 2000. This is a critical timeframe for observation given the sharp rise in the use of …

Estimating Oil Concentration And Flow Rate With Calibrated Vessel-Mounted Acoustic Echo Sounders, Thomas C. Weber, Alex De Robertis, Shep Smith, Samuel F. Greenaway, Larry A. Mayer, Glen Rice

Center for Coastal and Ocean Mapping

As part of a larger program aimed at evaluating acoustic techniques for mapping the distribution of subsurface oil and gas associated with the Deepwater Horizon-Macondo oil spill, observations were made on June 24 and 25, 2010 using vessel-mounted calibrated single-beam echo sounders on the National Oceanic and Atmospheric Administration ship Thomas Jefferson. Coincident with visual observations of oil at the sea surface, the 200-kHz echo sounder showed anomalously high-volume scattering strength in the upper 200 m on the western side of the wellhead, more than 100 times higher than the surrounding waters at 1,800-m distance from the wellhead, …

Review Of Adriana Novoa And Alex Levine, From Man To Ape: Darwinism In Argentina, 1870-1920, Julia E. Rodriguez

History

No abstract provided.

Economic Development: Marketing Strategy, Submitted To The City Of Manchester, Nh December 2011, Moran, Stahl & Boyer: Site Selection And Economic Development Consultants

Manchester Research Group

Overview of potential economic opportunities, a marketing strategy for economic growth, and an evaluation of resources to support economic growth in Manchester, N.H.

A Comparison Of Presettlement And Modern Forest Composition Along An Elevation Gradient In Central New Hampshire, Matthew A. Vadeboncoeur, Steven P. Hamburg, Charles V. Cogbill, Wendy Y. Sugimura

Earth Systems Research Center

Tree species composition is influenced not only by edaphic and climatic factors but also by natural and human-caused disturbances. To understand interactions among these influences, we compared forest species composition data from the time of European settlement with modern data. We derived elevation data for 2529 trees mapped by early land surveys (1770–1850) across a 1000 m elevation gradient in central New Hampshire and compared these with modern data (2004–2009) from the Forest Inventory and Analysis program (123 plots containing 2126 trees) and from permanent plots representing case studies of different land-use histories. Spruce and beech are much less abundant …

Unh Climate Change Assessment To Be Released At Dec. 2 Coastal Climate Summit, David Sims

Media Relations

No abstract provided.