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Effects Of Keratin Filaments On Erk Signaling During Fas-Induced Death Of Cervical Cancer (Hela) Cells, Amanda Berger
Effects Of Keratin Filaments On Erk Signaling During Fas-Induced Death Of Cervical Cancer (Hela) Cells, Amanda Berger
Honors Theses and Capstones
Survival of cancer cells is influenced by a variety of factors, including physical elements such as keratin filaments. We know HeLa cells containing or lacking keratin 8/18 intermediate filaments (K+ and K- cells, respectively) are more sensitive to the death-inducing effects of Fas agonist compared to the cytokines tumor necrosis factor alpha (TNF-α) or TNF-related apoptosis-inducing ligand. Additionally, K- cells are more sensitive to Fas-induced death than K+ as shown by previous studies using mitochondrial activity and caspase activation assays. In the current study we tested the hypothesis that keratin filaments associate with the mitogen activated protein kinase (MAPK) cascade …
Investigating The Interactions Between Cyanobacteria And Vibrio Parahaemolyticus, Caroline E. Ward
Investigating The Interactions Between Cyanobacteria And Vibrio Parahaemolyticus, Caroline E. Ward
Honors Theses and Capstones
One well-known pathogen that has been the topic of many recent studies is Vibrio parahaemolyticus, which causes thousands of foodborne illnesses a year, mostly from the ingestion of raw or undercooked oysters. It has been shown cyanobacteria can act as a long-term reservoir of Vibrio cholerae, another pathogenic Vibrio, by encasing the cells within mucilaginous sheaths during which Vibrios enter a viable but non-culturable state. In this study we investigated the interaction of V. parahaemolyticus with cyanobacteria to determine whether cyanobacteria aid in the longevity and survival of V. parahaemolyticus. We found that non-pathogenic V. parahaemolyticus …
Diel Vertical Migration Strategies Of Zooplankton In Oligotrophic Russell Pond, New Hampshire, Kelsey Ann Dobe
Diel Vertical Migration Strategies Of Zooplankton In Oligotrophic Russell Pond, New Hampshire, Kelsey Ann Dobe
Honors Theses and Capstones
Russell Pond is an ultra-oligotrophic lake with low chlorophyll a (1.9 mg L-1), total phosphorus (3.4 mg L-1), high Secchi Disk (10.4 m) and high light transmission (water coefficient of water, kw=0.33). Vertical migration of Chaoborus, Bosmina, Daphnia, and copepods were examined using net collections of zooplankton discrete depth counts and sonar. Three contrasting patterns of vertical migration were observed in Russell Pond. Chaoborus punctipennis larvae vertical migration began at 7 pm and migrated through the entire lake water column, a total of 23 m from the sediments to the surface water in …