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Electronic Theses and Dissertations

Theses/Dissertations

1983

Biology

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Interaction Of Polycyclic Aromatic Hydrocarbons With The Aryl Hydrocarbon Hydroxylase Enzyme System In Normal And Neoplastic C3h Mouse Embryo Cell Lines., Malcolm Mark. Feeley Jan 1983

Interaction Of Polycyclic Aromatic Hydrocarbons With The Aryl Hydrocarbon Hydroxylase Enzyme System In Normal And Neoplastic C3h Mouse Embryo Cell Lines., Malcolm Mark. Feeley

Electronic Theses and Dissertations

Dept. of Biological Sciences. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .F445. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


The Toxicological Significance And Etiology Of The Dieldrin (Heod)-Induced Hyperglycemic Response In The Immature And Adult Rat., Glyn Robert. Fox Jan 1983

The Toxicological Significance And Etiology Of The Dieldrin (Heod)-Induced Hyperglycemic Response In The Immature And Adult Rat., Glyn Robert. Fox

Electronic Theses and Dissertations

Rats were given 1 LD50 of HEOD. Plasma glucose was elevated in five day old rats, (17% at one hour) and in adults (45 and 38% at one and three hours). Hepatic glycogen was reduced in immature rats only, (22 - 16% at one hour). Thus, dieldrin does not alter carbohydrate metabolism in immature rats, but causes hyperglycemia in adults. Hepatic fructose-1,6-diphosphatase activity was elevated (17% at one hour) in five and decreased (10% at three hours) in ten day old rats. Phosphoenolpyruvate carboxykinase (PEPCK) activity was increased (30%) in adults at one hour, and in all ages, at three …


Synthetic And Biochemical Studies With 4-Deoxy-4-Fluoro-D-Glucose., John. Samuel Jan 1983

Synthetic And Biochemical Studies With 4-Deoxy-4-Fluoro-D-Glucose., John. Samuel

Electronic Theses and Dissertations

Dept. of Chemistry and Biochemistry. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .S169. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


In Vivo Sister Chromatid Exchanges: A Test System Monitoring Environmental Genotoxicity., Bichitra Nanda. Nayak Jan 1983

In Vivo Sister Chromatid Exchanges: A Test System Monitoring Environmental Genotoxicity., Bichitra Nanda. Nayak

Electronic Theses and Dissertations

An in vivo sister chromatid exchange (SCE) assay system for monitoring environmental genotoxicity, using bone marrow cells has been developed, tested and applied to groups of inbred and wild mice under various environmental conditions. The best results were obtained with nine, serial, intraperitoneal injections of 5-bromo-2'-deoxyuridine (BUdR) (40 (mu)g/g of body weight) and 5-fluorodeoxyuridine (FUdR) (2 (mu)g/g of b.w.) and then with 5 (mu)g/g of b.w. of colchicine, given on the 27th hour following the first injections of BUdR/FUdR. The mice were sacrificed 3 hours later. With the above injection schedule, male mice of C3H/HeJ and C57BL/6J maintained in the …


Spectrophotometric Determination Of Calcium, Magnesium And Inorganic Phosphate In Cerebrospinal Fluid., Betty Lay Hua. Lee Jan 1983

Spectrophotometric Determination Of Calcium, Magnesium And Inorganic Phosphate In Cerebrospinal Fluid., Betty Lay Hua. Lee

Electronic Theses and Dissertations

Dept. of Chemistry and Biochemistry. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .L44. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


A Light And Transmission Electron Microscopical Characterization Of Contact Sensitivity In The Mouse., Sheila Mary Fairley. Mckee-Protopapas Jan 1983

A Light And Transmission Electron Microscopical Characterization Of Contact Sensitivity In The Mouse., Sheila Mary Fairley. Mckee-Protopapas

Electronic Theses and Dissertations

Dept. of Biological Sciences. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .M344. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


Long-Arm Thiolated Polyacrylamide Beads And Their Application In Coupling Experiments With Papain., Beverly Ann. Kristalovich Jan 1983

Long-Arm Thiolated Polyacrylamide Beads And Their Application In Coupling Experiments With Papain., Beverly Ann. Kristalovich

Electronic Theses and Dissertations

Dept. of Chemistry and Biochemistry. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .K747. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


A Fluid Inclusion Study Of The Nanisivik Lead-Zinc Deposit, Baffin Island, N.W.T., Kenneth C. Mcnaughton Jan 1983

A Fluid Inclusion Study Of The Nanisivik Lead-Zinc Deposit, Baffin Island, N.W.T., Kenneth C. Mcnaughton

Electronic Theses and Dissertations

Dept. of Geology and Geological Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .M353. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.A.Sc.)--University of Windsor (Canada), 1983.


A Fluid Inclusion Study Of The Wheal Remfry Breccia, Cornwall, U.K., Simon D. Taylor Jan 1983

A Fluid Inclusion Study Of The Wheal Remfry Breccia, Cornwall, U.K., Simon D. Taylor

Electronic Theses and Dissertations

Dept. of Geology and Geological Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .T395. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


A Comparison Of Aryl Hydrocarbon Hydroxylase Induction Phenotypes Among And Within Cell Lines., Cynthia Jane. Forster-Gibson Jan 1983

A Comparison Of Aryl Hydrocarbon Hydroxylase Induction Phenotypes Among And Within Cell Lines., Cynthia Jane. Forster-Gibson

Electronic Theses and Dissertations

Aryl hydrocarbon hydroxylase (AHH) activity in two cell lines - Hepa-1c1 and H4IIE-C3 was induced to similar levels by benzo(a)-anthracence. Absolute levels varied between experiments. Relative levels, determined within experiments, were stable between experiments. Nuclear translocation of Ah receptor occurred in these lines and the noninducible HTC-SR cell line. No receptor was detectable in the noninducible Vero cell line. The Ah receptor appeared to be necessary, but not sufficient for AHH induction. Two subclones assessed for their level of inducible AHH activity, had significantly lower levels, two had approximately the same level, and three had significantly higher levels (p < 0.005) than their progenitor - Hepa-1c1. The relative level was 0.14 (+OR-) 0.09 for Hepa-1c1 subclone 1 (Hs-1), and 1.37 (+OR-) 0.48 for subclone 9 (Hs-9). These levels were stable: over 2.4 years (Hs-1), or 1 year (Hs-9); throughout the year; through routine cell storage at -80(DEGREES)C; and over approximately 190 (Hepa-1c1), 160 (Hs-1), and 150 (Hs-9) generations. The relative levels were similar when activity was induced with either 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), or benzo(a)anthracene (BA). The high percentage of variant subclones and the stability of the relative levels of AHH induction of Hs-1 and Hs-9 suggests that an epigenetic mechanism contributes to control of AHH induction. No inducible activity was seen in two Vero subclones. There was no apparent correlation between relative level of induced AHH activity and: (1) quantity of total Ah receptor (cytosol plus nuclear) per mg protein; (2) receptor affinity for {('3)H} TCDD (Kd values were 7.5 nM (Hepa-1c1), 7.7 nM (Hs-1) and 7.9 nM (Hs-9; (3) subcellular distribution of {('3)H} TCDD; (4) specificity of binding and saturable nature of binding; or (5) lack of induction of receptor by BA. There was no significant difference in the quantity of nuclear receptor (per mg protein) between Hepa-1c1 and Hs-1, but significantly more nuclear receptor in Hs-9 compared to Hepa-1c1. Co-ordinate measurement of nuclear receptor and absolute induced AHH activity indicated a correlation of 0.62 between these parameters. The data suggest that the extent of the correlation between the quantity of Ah receptor translocating to the nucleus and level of induced AHH activity is mediated by other factors.Dept. of Biological Sciences. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .F677. Source: Dissertation Abstracts International, Volume: 44-03, Section: B, page: 0675. Thesis (Ph.D.)--University of Windsor (Canada), 1983.


Habitat Use Of Individuals And Populations Of Peromyscus Leucopus And Microtus Pennsylvanicus During Periods Of High And Low Rodent Density., Janice Anne. Longley-Wilson Jan 1983

Habitat Use Of Individuals And Populations Of Peromyscus Leucopus And Microtus Pennsylvanicus During Periods Of High And Low Rodent Density., Janice Anne. Longley-Wilson

Electronic Theses and Dissertations

Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


Investigation Of The K"Onig Reaction For The Determination Of Cyanide And Thiocyanate In Biological Samples Development Of A Continuous Monitoring Assay For Rhodanese Activity In Biological Samples., Ajit. Sharma Jan 1983

Investigation Of The K"Onig Reaction For The Determination Of Cyanide And Thiocyanate In Biological Samples Development Of A Continuous Monitoring Assay For Rhodanese Activity In Biological Samples., Ajit. Sharma

Electronic Theses and Dissertations

Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


A Study Of The Volcanic Rocks On The Southern Half Of Carriacou, Grenadines, West Indies., Gary. Caldwell Jan 1983

A Study Of The Volcanic Rocks On The Southern Half Of Carriacou, Grenadines, West Indies., Gary. Caldwell

Electronic Theses and Dissertations

Dept. of Geology and Geological Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .C353. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


Neutral Protease Activity During The Course Of Influenza Virus Infection., Mary Elizabeth. Ewasyshyn Jan 1983

Neutral Protease Activity During The Course Of Influenza Virus Infection., Mary Elizabeth. Ewasyshyn

Electronic Theses and Dissertations

Neutral protease activity was quantified during the course of influenza virus infection in both embryonated chicken eggs and cell culture systems. Characterization and monitoring changes of trypsin-like activities in egg embryonal fluids and subcellular fractions of HBSC-1 and primary chick embryo cells (CE) were carried out by a sensitive fluorometric technique. Antigenic subtypes of influenza A viruses studied were H1N1 strains PR/8/34, Brazil/8/78, FM/1/47, the H3N2 strain Bangkok/1/80, the H5N9 Turkey/Ontario/7732/66 and the Sendai strain of parainfluenza type 1 virus. Viruses allantoically inoculated into embryonated eggs markedly altered protease activity of fluid in the cavity. The three distinct types of …


Competition In Natural And Experimental Monocultures Of Xanthium Strumarium L., Jess Konrad. Zimmerman Jan 1983

Competition In Natural And Experimental Monocultures Of Xanthium Strumarium L., Jess Konrad. Zimmerman

Electronic Theses and Dissertations

Dept. of Biological Sciences. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .Z555. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


Contaminant Hydrogeology Of The Walpole Island Indian Reserve, Lambton County, Ontario, Canada., Riyazali N. Jiwani Jan 1983

Contaminant Hydrogeology Of The Walpole Island Indian Reserve, Lambton County, Ontario, Canada., Riyazali N. Jiwani

Electronic Theses and Dissertations

Dept. of Geology and Geological Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .J583. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.A.Sc.)--University of Windsor (Canada), 1983.


A Study Of The Differences In The Kinetic Properties Of Human Creatine Kinase Isoenzymes., Georges Lindsay. Chong Jan 1983

A Study Of The Differences In The Kinetic Properties Of Human Creatine Kinase Isoenzymes., Georges Lindsay. Chong

Electronic Theses and Dissertations

Dept. of Chemistry and Biochemistry. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .C565. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


The Development Of An Automated Technique For The Determination Of Lecithin A Study Of Lecithin Levels In Serum Of Normal Subjects And Patients Under Cardiac Care., Sheila Carol. Boss Jan 1983

The Development Of An Automated Technique For The Determination Of Lecithin A Study Of Lecithin Levels In Serum Of Normal Subjects And Patients Under Cardiac Care., Sheila Carol. Boss

Electronic Theses and Dissertations

Dept. of Chemistry and Biochemistry. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .B677. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


Selected Trace Metal Concentrations In Groundwater, Stream And Soils In Essex County, Ontario., Christine Helen Galinski Jan 1983

Selected Trace Metal Concentrations In Groundwater, Stream And Soils In Essex County, Ontario., Christine Helen Galinski

Electronic Theses and Dissertations

Dept. of Geology and Geological Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .G344. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


Structural Studies Of Electroless Thin Ni-P Films Grown In An Alkaline Environment., Raul. Cortijo Jan 1983

Structural Studies Of Electroless Thin Ni-P Films Grown In An Alkaline Environment., Raul. Cortijo

Electronic Theses and Dissertations

Dept. of Physics. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1983 .C677. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.


Well-Log Analysis Of The Milk River (Campanian) Strata Of Southwestern Saskatchewan., Maghar. Singh Jan 1983

Well-Log Analysis Of The Milk River (Campanian) Strata Of Southwestern Saskatchewan., Maghar. Singh

Electronic Theses and Dissertations

Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1983.