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Liver Cancer: Current And Future Trends Using Biomaterials, Sue Anne Chew, Stefania Moscato, Sachin George, Bahareh Azimi, Serena Danti
Liver Cancer: Current And Future Trends Using Biomaterials, Sue Anne Chew, Stefania Moscato, Sachin George, Bahareh Azimi, Serena Danti
Health & Biomedical Sciences Faculty Publications and Presentations
Hepatocellular carcinoma (HCC) is the fifth most common type of cancer diagnosed and the second leading cause of death worldwide. Despite advancement in current treatments for HCC, the prognosis for this cancer is still unfavorable. This comprehensive review article focuses on all the current technology that applies biomaterials to treat and study liver cancer, thus showing the versatility of biomaterials to be used as smart tools in this complex pathologic scenario. Specifically, after introducing the liver anatomy and pathology by focusing on the available treatments for HCC, this review summarizes the current biomaterial-based approaches for systemic delivery and implantable tools …
Multidirectional Pin-On-Disk Testing Device To Evaluate The Cross-Shear Effect On The Wear Of Biocompatible Materials, Vicente Cortes, Carlos A. Rodriguez Betancourth, Javier A. Ortega, Hasina Huq
Multidirectional Pin-On-Disk Testing Device To Evaluate The Cross-Shear Effect On The Wear Of Biocompatible Materials, Vicente Cortes, Carlos A. Rodriguez Betancourth, Javier A. Ortega, Hasina Huq
Mechanical Engineering Faculty Publications and Presentations
One of the main causes of hip prostheses failure is the premature wear of their components. Multi-directional motion or “cross-shear” motion has been identified as one of the most significant factors affecting the wear rate of UHMWPE in total hip joint replacement prostheses. To better evaluate the effect of this cross-shear motion on the tribological behavior of different biomaterials, a new wear testing device has been designed and developed. This new instrument is capable to reproduce the “cross-shear” effect with bidirectional motion on bearing materials and to determine coefficient of friction (COF) between surfaces during testing. To validate the functionality …
Forcespinning Technique For The Production Of Poly(D,L-Lactic Acid) Submicrometer Fibers: Process–Morphology–Properties Relationship, Victoria Padilla-Gainza, Graciela Morales, Heriberto Rodríguez-Tobías, Karen Lozano
Forcespinning Technique For The Production Of Poly(D,L-Lactic Acid) Submicrometer Fibers: Process–Morphology–Properties Relationship, Victoria Padilla-Gainza, Graciela Morales, Heriberto Rodríguez-Tobías, Karen Lozano
Mechanical Engineering Faculty Publications and Presentations
This work addresses a systematic study for the process development and optimization of poly(d,l-lactic acid) (PDLLA) submicrometer fibers utilizing the centrifugal spinning technique known as Forcespinning. This study analyzes the effect of polymer concentration (8, 10, and 12 wt %) and angular speed on the fiber morphology, diameter distribution, and fiber yield. The increase in polymer concentration and angular speed favored the formation of continuous and homogeneous submicrometer fibers with an absence of bead formation and higher output. The optimal conditions were established considering the morphological characteristics that exhibit a greater surface area (homogeneous and submicrometer fibers); and they were …