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Standardized Oral Health Assessment And Scoring Using Digital Imaging, Cindy L. Munro, Paula Louise Cairns, Xusheng Chen, Gwendolyn J. Good, Kevin Edward Kip
Standardized Oral Health Assessment And Scoring Using Digital Imaging, Cindy L. Munro, Paula Louise Cairns, Xusheng Chen, Gwendolyn J. Good, Kevin Edward Kip
USF Patents
System and methodology objectively capture clinical data on oral health and provide standardized scoring for quantifying oral health. The process of capturing clinical data is based on use of an intraoral camera with imaging software that has the capacity to capture digital images of all tooth surfaces. Digital plaque data are collected in a standardized manner per tooth, and with the ability to select optimal frames for analysis. Data are extracted per tooth into a software program. Color classification of each pixel is determined by the software program using an algorithm that makes use of red/green/blue color code combinations. These …
System And Method For Adaptive Ofdm Guards, Ali Faith Demir, Huseyin Arslan
System And Method For Adaptive Ofdm Guards, Ali Faith Demir, Huseyin Arslan
USF Patents
A system and method for reducing the OFDM out-of-band emissions (OOBE) by utilizing a transmitter windowing operation that smooths the inherent rectangular pulse shape of the OFDM signals. The technique retains the main design of the OFDM receivers and provides backward compatibility for the existing OFDM-based systems. The guard band and the window parameters that control the guard duration are jointly optimized regarding the use case and the power offset between the users. To fully exploit and further increase the potential of adaptive guards, an interference-based scheduling algorithm is proposed as well.
Ionizing Radiation Resistant Coatings, Julie P. Harmon
Ionizing Radiation Resistant Coatings, Julie P. Harmon
USF Patents
A mixture of a lacquer and carbon nanotubes that form a cross-linked network to convert excitation energy into non-chemistry inducing energy in a cured lacquer.
Horizontally-Scalable Microcavity-Enhanced Raman Scattering Integrated Platform For Multigas Chemical Analysis, Andreas Muller
Horizontally-Scalable Microcavity-Enhanced Raman Scattering Integrated Platform For Multigas Chemical Analysis, Andreas Muller
USF Patents
An integrated approach to optical sensing (Ëcm3 excluding electronics) at concentrations of parts-per-million or less (ppm). The invention enables the trace detection of chemicals in fluids (gas or liquid) in a highly integrated package. The simultaneous detection of any number of Raman active molecular species (including isotopes) may be achieved in a scalable, low-cost manner.
Percutaneous Endoscopic Gastronomy Tube For Optimized Gastric Sumping, Justin Robert Daggett
Percutaneous Endoscopic Gastronomy Tube For Optimized Gastric Sumping, Justin Robert Daggett
USF Patents
An improved percutaneous endoscopic gastrostomy (PEG) tube that allows continuous suctioning/sumping without occlusion of the tube by the gastric wall. The PEG tube includes a hollow drainage tubing coupled to a ventilated bell cap. The bell cap can be open or closed to the external environment is ventilated via apertures, crenellations and grooves, and hemispherical arches. The PEG tube minimizes, or completely eliminates, the need for a user thereof to frequently flush the tube, thus also curtailing intermittent suctioning and allowing for longer periods of uninterrupted drainage. Furthermore, the PEG tubes of the current invention reduce clogging of the tube …
Small Molecules That Mimic Or Antagonize Actions Of Granulocyte Colony-Stimulating-Factor (G-Csf), Juan Sanchez-Ramos, Vasyl Sava, Shijie Song, Said Sebti
Small Molecules That Mimic Or Antagonize Actions Of Granulocyte Colony-Stimulating-Factor (G-Csf), Juan Sanchez-Ramos, Vasyl Sava, Shijie Song, Said Sebti
USF Patents
Described herein are compound for the modulation of the G-CSF receptor. The compounds may act as agonists, antagonists, and/or mixed or partial agonists/antagonists of G-CSF. Further provided herein are methods of treating a condition, including, for example, a neurodegenerative disease, by administering a compound as detailed herein.
Nutraceutical Co-Crystal Compositions, Michael John Zaworotko, Heather Clarke, Arora Kapildev, Padmini Kavuru, Roland Douglas Shytle, Twarita Pujari, Lissette Marshall, Tien Teng Ong
Nutraceutical Co-Crystal Compositions, Michael John Zaworotko, Heather Clarke, Arora Kapildev, Padmini Kavuru, Roland Douglas Shytle, Twarita Pujari, Lissette Marshall, Tien Teng Ong
USF Patents
Co-crystals comprising at least one nutraceutical compound and at least one co-crystal former with or without impurities. These co-crystals may be included in compositions (optionally also including other components such as pharmaceutically acceptable excipients, other nutritional supplements, etc.) having utility as pharmaceuticals, nutraceuticals, nutritional supplements, and foodstuffs.
Antimicrobials From An Epigenetics Based Fungal Metabolite Screening Program, Danielle H. Demers, Bill J. Baker, Ala Azhari, Renee M. Fleeman, Dennis E. Kyle, Lindsey Neil Shaw
Antimicrobials From An Epigenetics Based Fungal Metabolite Screening Program, Danielle H. Demers, Bill J. Baker, Ala Azhari, Renee M. Fleeman, Dennis E. Kyle, Lindsey Neil Shaw
USF Patents
Novel antimicrobial compounds against drug targets such as Eskape pathogens, Leishmania donovani, Mycobacterium tuberculosis, Clostridium difficile, Naegleria fowleri, and cancer are presented herein.
Adjustable Prosthetic Ankles, Michael Jason Highsmith, Derek James Lura
Adjustable Prosthetic Ankles, Michael Jason Highsmith, Derek James Lura
USF Patents
A method for adjusting a flexion angle of a prosthetic ankle includes a user adjusting a relative angle between first and second coupling members of the prosthetic ankle using a flexion angle adjustment mechanism of the prosthetic ankle that requires no tools to adjust.
Position/Weight-Activated Knee Locking Mechanism, Tyagi Ramakrishnan, Kyle B. Reed
Position/Weight-Activated Knee Locking Mechanism, Tyagi Ramakrishnan, Kyle B. Reed
USF Patents
A passive knee locking mechanism using the position of the shank and the weight of the user to lock. The mechanism has translational motion, which allows the shank to move linearly along the sagittal/vertical plane, which locks and unlocks the knee, and rotational motion for the shank to swing when unlocked. The knee block, which is disposed at the top of the shank, has a spur gear that locks with a matching gear rack on the top plate of the knee housing. The side plates for the knee housing have a linear path that makes for the translational motion. During …
Systems And Methods For Challengeless Coauthentication, Jarred Adam Ligatti
Systems And Methods For Challengeless Coauthentication, Jarred Adam Ligatti
USF Patents
A system and method of authentication that avoids authentication challenges is described. In operation, an authenticator receives a first request to access a resource generated by a requestor and a participation message generated by a collaborator. The authenticator computing device then analyzes the first request and the participation message to determine whether the requestor requesting access to the resource should be granted access and grants the requestor access to the resource based upon the analysis of the first request to access a resource and the participation message.
Methods Of Treating Epilepsy Using Neural Stem Cells That Express Nanog, Ssea-4, Oct-4, Mir-34b, Mir-34c And Mir-592, Cesario Venturina Borlongan, Carmelina Gemma, Fernando L. Vale
Methods Of Treating Epilepsy Using Neural Stem Cells That Express Nanog, Ssea-4, Oct-4, Mir-34b, Mir-34c And Mir-592, Cesario Venturina Borlongan, Carmelina Gemma, Fernando L. Vale
USF Patents
Provided herein is a method of diagnosing or prognosing an epilepsy or epilepsy-related disorder. Also provided herein is a method of treating an epilepsy or epilepsy-related disorder. Further provided are non-epileptic and epileptic neural stem cells and cell cultures.
Antimicrobials From An Epigenetics Based Fungal Metabolite Screening Program, Danielle H. Demers, Bill J. Baker, Ala Azhari, Renee M. Fleeman, Dennis E. Kyle, Lindsey Neil Shaw
Antimicrobials From An Epigenetics Based Fungal Metabolite Screening Program, Danielle H. Demers, Bill J. Baker, Ala Azhari, Renee M. Fleeman, Dennis E. Kyle, Lindsey Neil Shaw
USF Patents
Novel antimicrobial compounds against drug targets such as Eskape pathogens, Leishmania donovani, Mycobacterium tuberculosis, Clostridium difficile, Naegleria fowleri, and cancer are presented herein.
Antibacterial S-Heterosubstituted Disulfides, Edward Turos, Praveen Ramaraju
Antibacterial S-Heterosubstituted Disulfides, Edward Turos, Praveen Ramaraju
USF Patents
Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tularensis. The present invention provides compounds, methods and compositions effective to treat microbial/bacterial infections, and, especially, infections arising from bacteria which have developed resistance to conventional antibiotics.
Antimicrobial Analogues Of Gramicidin S, Juan R. Del Valle, Lindsey Shaw
Antimicrobial Analogues Of Gramicidin S, Juan R. Del Valle, Lindsey Shaw
USF Patents
Disclosed herein are N-aminated variants of Gramicidin S and methods of using the same for treating infections in a subject.
γ-Aa-Peptide Stat3/Dna Inhibitors And Methods Of Use, Said M. Sebti, Jianfeng Cai
γ-Aa-Peptide Stat3/Dna Inhibitors And Methods Of Use, Said M. Sebti, Jianfeng Cai
USF Patents
STAT3 hyperphosphorylation, dimerization and DNA binding are required for its ability to contribute to malignant transformation. As such, STAT3 has been recognized as a promising target for cancer therapy. Although a number of inhibitors of STAT3-STAT3 dimerization have been reported, molecular ligands that prevent interactions between STAT3 and DNA are very rare. The γ-AApeptide-based one-bead-one-compound (OBOC) combinatorial library was used, and identified γ-AApeptides that can selectively inhibit STAT3/DNA interaction and suppress the expression levels of STAT3 target genes in intact cells. The results not only validate γ-AApeptides as novel inhibitors of STAT3 signaling pathway, but also demonstrate that in addition …
Metal Chelating Composites, Methods Of Using Composites, And Methods Of Making Composites, John Norbert Kuhn, Henry Lee Woodcock, Mohamed A. Barakat, Mansour A. Alghamdi, Abdulrahman Alkhalaf
Metal Chelating Composites, Methods Of Using Composites, And Methods Of Making Composites, John Norbert Kuhn, Henry Lee Woodcock, Mohamed A. Barakat, Mansour A. Alghamdi, Abdulrahman Alkhalaf
USF Patents
Embodiments of the present disclosure provide for composites, methods of making composites, methods of removing a metal from a fluid, and the like.
Hormone Treatment For Age-Related Hearing Loss-Presbycusis, Robert Dana Frisina, Joseph Paul Walton, Bo Ding, Xiaoxia Zhu
Hormone Treatment For Age-Related Hearing Loss-Presbycusis, Robert Dana Frisina, Joseph Paul Walton, Bo Ding, Xiaoxia Zhu
USF Patents
Permanent hearing loss or deafness affects about 15% of people worldwide, about 40 million in the US alone. There are currently no FDA-approved drugs on the market in the US, or anywhere in the world that prevent, treat or reverse permanent hearing loss or deafness. Age-related hearing loss (ARHL) is one of the most common forms of permanent hearing loss and deafness. ARHL is the #1 neurodegenerative disorder, #1 communication disorder, and 1 of the top 3 chronic medical conditions (along with arthritis & cardiovascular diseases) of our aged population. The incidence of ARHL is increasing due to the âBaby …
Combined Minimization Of Intersymbol Interference (Isi) And Adjacent Channel Interference (Aci), Berker Pekoz, Selcuk Kose, Huseyin Arslan
Combined Minimization Of Intersymbol Interference (Isi) And Adjacent Channel Interference (Aci), Berker Pekoz, Selcuk Kose, Huseyin Arslan
USF Patents
Adaptive windowing of insufficient cyclic prefix (CP) for joint minimization of intersymbol interference (ISI) and adjacent channel interference (ACI) is provided. The proposed subcarrier specific windowing scheme improves the signal-to-interference ratio (SIR) even when the cyclic prefix (CP) is insufficient. Average optimal window lengths depend only on the power density profiles (PDPs), and although instantaneous optimal window lengths depend on users' channel impulse responses (CIRs), fluctuation is little. Therefore, subcarrier specific windowing outperforms fixed windowing, even with outdated window lengths in the case of powerful interferers.
Ischemic Tissue Cell Therapy, Paul R. Sanberg, Alison E. Willing
Ischemic Tissue Cell Therapy, Paul R. Sanberg, Alison E. Willing
USF Patents
The present invention is directed to compositions and methods for treatment of ischemic diseases and conditions, particularly myocardial, CNS/brain and limb ischemia. More particularly, the present invention provides methods of treating disorders by administering monocytes obtained from blood, including umbilical cord blood, peripheral blood, or bone marrow to an individual in need of treatment, wherein the drug is administered to the individual at a time point specifically determined to provide therapeutic efficacy. In one embodiment, the cells are for injection into ischemic myocardium for the treatment of angina.
Waterproof Shape-Shifting Surface, Andrew Jason Katz, Craig Lusk
Waterproof Shape-Shifting Surface, Andrew Jason Katz, Craig Lusk
USF Patents
The first objective of this paper is to take an existing design for a shape-shifting surface (SSS) and make it waterproof, making it an effective barrier to fluid flow. The second objective is to minimize internal stresses in the device during operation, by optimizing the kinematic geometry of the SSS. The first objective was achieved by adding a waterproof membrane between the layers of the SSS, where the membrane had an origami fold pattern that enables the membrane to mimic the kinematics of the SSS. The second objective was achieved by creating a two objective optimization routine, which determined the …
Compositions And Methods For Treating Stroke, David Andrew Decker, Keith Pennypacker
Compositions And Methods For Treating Stroke, David Andrew Decker, Keith Pennypacker
USF Patents
Provided herein is a method of treating a subject believed to have suffered a stroke. This method comprises administering to the subject a therapeutically effective amount of a composition comprising conivaptan or an active derivative, stereoisomer, pro-drug, or pharmaceutically acceptable salt thereof.
Intracorporal Ultra High Purity Calcium Sulfate Cast Mixed With Antimicrobials For The Treatment Of Penile Implant Infections, Rafael Carrion, Daniel Roberto Martinez, Eihab Akary, Tariq Said Hakky
Intracorporal Ultra High Purity Calcium Sulfate Cast Mixed With Antimicrobials For The Treatment Of Penile Implant Infections, Rafael Carrion, Daniel Roberto Martinez, Eihab Akary, Tariq Said Hakky
USF Patents
The present invention includes a method for treating penile implant infections that uses a synthetic high-purity calcium sulfate mixed with antimicrobials, which is capable of providing prolonged exposure of antimicrobials to the infection site and capable of acting as an intracorporal filler preventing fibrosis and loss of phallic length. The technique is especially useful for high-risk patients, and provides another medium for which antimicrobial agents can be delivered to a surgical infection site while at the same time acting as a filler, preventing fibrosis, and loss of the space. The antimicrobial cast lasts 4-6 weeks, making timely re-implantation easier, and …
Linear Bi-Stable Compliant Crank-Slider-Mechanism, Ahmad Alqasimi, Craig Lusk
Linear Bi-Stable Compliant Crank-Slider-Mechanism, Ahmad Alqasimi, Craig Lusk
USF Patents
A linear element with two stable points, it can be used as trust element allows for change in length. It can transform structure from one shape to another thus allowing for morphable configuration. A new model is presented herein for a linear bi-stable compliant mechanism and design guidelines for its use. The mechanism is based on the crank-slider mechanism. This model takes into account the first mode of buckling and post-buckling behavior of a compliant segment to describe the mechanism's bi-stable behavior. The kinetic and kinematic equations, derived from the Pseudo-Rigid-Body Model, were solved numerically and are represented in plots. …
Expandable Intervertebral Cage, Kamran Aghayev, James J. Doulgeris, Sabrina A. Gonzalez Blohm, Frank D. Vrionis
Expandable Intervertebral Cage, Kamran Aghayev, James J. Doulgeris, Sabrina A. Gonzalez Blohm, Frank D. Vrionis
USF Patents
A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed.
Hydrocolloid Dressing For Precise Nipple Positioning After Nipple- Or Skin-Sparing Mastectomy, Deniz Dayicioglu, Rose Theresa Tillis
Hydrocolloid Dressing For Precise Nipple Positioning After Nipple- Or Skin-Sparing Mastectomy, Deniz Dayicioglu, Rose Theresa Tillis
USF Patents
An apparatus and method/technique that uses a hydrocolloid dressing that results in both improved circulation and aesthetic success with optimal nipple positioning. By applying a specific pattern of the adhesive hydrocolloid dressing to the mastectomy flaps, stability of the nipple-areolar complex (NAC) in the desired higher position could be achieved. In operation, the hydrocolloid dressing is placed over the breast after surgery (while also leaving the incision site uncovered), and remains in place for a suitable amount of time. The hydrocolloid dressing can be applied on either side or both sides of the nipple during expansion phase to precisely control …
N2n N4-Disubstituted Quinazoline-2,4-Diamines And Uses Thereof, Roman Manetsch, Kurt S. Van Horn, Whittney Burda, Lindsey N. Shaw, Renee Fleeman, Megan Barber, David Lawrence Flanigan
N2n N4-Disubstituted Quinazoline-2,4-Diamines And Uses Thereof, Roman Manetsch, Kurt S. Van Horn, Whittney Burda, Lindsey N. Shaw, Renee Fleeman, Megan Barber, David Lawrence Flanigan
USF Patents
Described herein are quinazoline-based compounds and formulations thereof. In some embodiments, the compounds and/or formulations thereof can be effective to inhibit and/or kill A. baumannii. Also described herein are methods of treating a subject in need thereof by administering to the subject in need thereof a quinazoline-based compound and/or formulation thereof to the subject in need thereof.
System And Method For Machine-To-Machine Communication In An Internet-Of-Things Network, Richard Dennis Gitlin, Mohamed Elkourdi, Asim Mazin
System And Method For Machine-To-Machine Communication In An Internet-Of-Things Network, Richard Dennis Gitlin, Mohamed Elkourdi, Asim Mazin
USF Patents
A system and method for Machine-to-Machine (M2M) communication over a transmission medium, including a novel random access protocol that is easy to implement, energy efficient, scalable and compatible with the limited-power and low complexity requirements of IoT devices. The proposed protocol utilizes a form of multiple hypothesis testing at the IoT gateway to determine the number of active IoT devices operating in the transmission medium to optimize the power levels of a Successive Interference Cancellation (SIC) receiver in order to distinguish between signals transmitted from different IoT devices on the same time and frequency. The use of beamforming exploits the …
Therapeutic Agent Applicators And Methods Of Using The Same, Steven E. Finkelstein, Matthew C. Biagioli, Mayer N. Fishman
Therapeutic Agent Applicators And Methods Of Using The Same, Steven E. Finkelstein, Matthew C. Biagioli, Mayer N. Fishman
USF Patents
The present application relates to applicators and methods for administering therapeutic agents to cancerous tissue. The applicators can be used to deliver radiation and additional therapeutic agents to cancerous tissue located in a subject.
Aging-Sensitive Recycling Sensors For Chip Authentication, Swaroop Ghosh, Cheng-Wei Lin
Aging-Sensitive Recycling Sensors For Chip Authentication, Swaroop Ghosh, Cheng-Wei Lin
USF Patents
Various devices, methods and systems are provided for aging-sensitive chip authentication. In one example, among others, a chip includes a reference Schmitt trigger ring oscillator (STRO) configured to enter a sleep mode during operation of the chip; a stressed STRO; a VDD charge pump configured to boost a positive voltage supplied to the stressed STRO during operation of the chip; and/or a GND charge pump configured to under-drive a ground voltage supplied to the stressed STRO during operation of the chip. In another example, a method includes detecting activation of a chip including a reference STRO and a stressed STRO …