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A Unified Inter-Host And In-Host Model Of Antibiotic Resistance And Infection Spread In A Hospital Ward, Lester Caudill, Barry Lawson May 2017

A Unified Inter-Host And In-Host Model Of Antibiotic Resistance And Infection Spread In A Hospital Ward, Lester Caudill, Barry Lawson

Department of Math & Statistics Faculty Publications

As the battle continues against hospital-acquired infections and the concurrent rise in antibiotic resistance among many of the major causative pathogens, there is a dire need to conduct controlled experiments, in order to compare proposed control strategies. However, cost, time, and ethical considerations make this evaluation strategy either impractical or impossible to implement with living patients. This paper presents a multi-scale model that offers promise as the basis for a tool to simulate these (and other) controlled experiments. This is a “unified” model in two important ways: (i) It combines inter-host and in-host dynamics into a single model, and (ii) …


Differential Equations Models Of Pathogen-Induced Single- And Multi-Organ Tissue Damage, Fiona Lynch Jan 2017

Differential Equations Models Of Pathogen-Induced Single- And Multi-Organ Tissue Damage, Fiona Lynch

Honors Theses

The rise of antibiotic resistance has created a significant burden on healthcare systems around the world. Antibiotic resistance arises from the increased use of antibiotic drugs and antimicrobial agents, which kill susceptible bacterial strains, but have little effect on strains that have a mutation allowing them to survive antibiotic treatment, defined as “resistant” strains. With no non-resistant bacteria to compete for resources, the resistant bacteria thrives in this environment, continuing to reproduce and infect the host with an infection that does not respond to traditional antibiotic treatment.

A number of strategies have been proposed to tackle the problem of antibiotic …


A Comprehensive Analysis Of Team Streakiness In Major League Baseball: 1962-2016, Paul H. Kvam, Zezhong Chen Jan 2017

A Comprehensive Analysis Of Team Streakiness In Major League Baseball: 1962-2016, Paul H. Kvam, Zezhong Chen

Department of Math & Statistics Faculty Publications

A baseball team would be considered “streaky” if its record exhibits an unusually high number of consecutive wins or losses, compared to what might be expected if the team’s performance does not really depend on whether or not they won their previous game. If an average team in Major League Baseball (i.e., with a record of 81-81) is not streaky, we assume its win probability would be stable at around 50% for most games, outside of peculiar details of day-to-day outcomes, such as whether the game is home or away, who is the starting pitcher, and so on.

In this …


Approaching Cauchy’S Theorem, Stephan Ramon Garcia, William T. Ross Jan 2017

Approaching Cauchy’S Theorem, Stephan Ramon Garcia, William T. Ross

Department of Math & Statistics Faculty Publications

We hope to initiate a discussion about various methods for introducing Cauchy’s Theorem. Although Cauchy’s Theorem is the fundamental theorem upon which complex analysis is based, there is no “standard approach.” The appropriate choice depends upon the prerequisites for the course and the level of rigor intended. Common methods include Green’s Theorem, Goursat’s Lemma, Leibniz’ Rule, and homotopy theory, each of which has its positives and negatives.


Multipliers Of Sequence Spaces, Raymond Cheng, Javad Mashreghi, William T. Ross Jan 2017

Multipliers Of Sequence Spaces, Raymond Cheng, Javad Mashreghi, William T. Ross

Department of Math & Statistics Faculty Publications

This paper is selective survey on the space lAp and its multipliers. It also includes some connections of multipliers to Birkhoff-James orthogonality.


Birkhoff–James Orthogonality And The Zeros Of An Analytic Function, Raymond Cheng, Javad Mashreghi, William T. Ross Jan 2017

Birkhoff–James Orthogonality And The Zeros Of An Analytic Function, Raymond Cheng, Javad Mashreghi, William T. Ross

Department of Math & Statistics Faculty Publications

Bounds are obtained for the zeros of an analytic function on a disk in terms of the Taylor coefficients of the function. These results are derived using the notion of Birkhoff–James orthogonality in the sequence space ℓp with p ∈ (1,∞), along with an associated Pythagorean theorem. It is shown that these methods are able to reproduce, and in some cases sharpen, some classical bounds for the roots of a polynomial.


A New Almost Difference Set Construction, David Clayton Jan 2017

A New Almost Difference Set Construction, David Clayton

Honors Theses

This paper considers the appearance of almost difference sets in non-abelian groups. While numerous construction methods for these structures are known in abelian groups, little is known about ADSs in the case where the group elements do not commute. This paper presents a construction method for combining abelian difference sets into nonabelian almost difference sets, while also showing that at least one known almost difference set construction can be generalized to the nonabelian case.


Toward A Scientific Investigation Of Convolutional Neural Networks, Anh Tran Jan 2017

Toward A Scientific Investigation Of Convolutional Neural Networks, Anh Tran

Honors Theses

This thesis does not assume the reader is familiar with artificial neural networks. However, to keep the thesis concise, it assumes the reader is familiar with the standard Machine Learning concepts of training set, validation set, and test set [1]. Their usage is intended to help ensure that the Machine Learning system can generalize its training from input examples used during its training to “similar” kinds of examples never used during its training.

The concept of a Convolutional Neural Network (CNN) is one of the most successful computational concepts today for solving image classification problems. However, CNNs are difficult and …


Quantum Groups And Knot Invariants, Greg A. Hamilton Jan 2017

Quantum Groups And Knot Invariants, Greg A. Hamilton

Honors Theses

Knot theory arguably holds claim to the title of the mathematical discipline with the most unusually diverse applications. A knot can be defined topologically as an embedding of S1 in R3. Naturally, two knots are topologically equivalent if one cannot be smoothly deformed into the other. The question of whether two knots are equivalent is highly non-trivial, and so the question of knot invariants used to distinguish knots has occupied knot theorists for over a century. Knot theory has found application in statistical mechanics [1], symbolic logic and set theory [2], quantum fi theory [3], quantum computing [4], etc. …


Differential Privacy For Growing Databases, Gi Heung (Robin) Kim Jan 2017

Differential Privacy For Growing Databases, Gi Heung (Robin) Kim

Honors Theses

Differential privacy [DMNS06] is a strong definition of database privacy that provides indi- viduals in a database with the guarantee that any particular person’s information has very little effect on the output of any analysis of the overall database. In order for this type of analysis to be practical, it must simultaneously preserve privacy and utility, where utility refers to how well the analysis describes the contents of the database.

An analyst may additionally wish to evaluate how a database’s composition changes over time. Consider a company, for example, that accumulates data from a growing base of customers. This company …