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A Noninvasive Measure Of The P300 In Rats Selectively Bred For Disparate Alcohol Preference During An Auditory Oddball Tas, Logan Michael Brewer
A Noninvasive Measure Of The P300 In Rats Selectively Bred For Disparate Alcohol Preference During An Auditory Oddball Tas, Logan Michael Brewer
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The utility of genetics for predicting alcoholism and alcohol-related disorders islimited given environmental variance and a finite understanding of all geneticcontributors. This has led to interest in phenotypic markers that can be used forclassifying individuals at heightened risk for developing alcoholism and alcohol-relateddisorders. One such marker is the P300, an event-related potential (ERP) observed tohave an attenuated amplitude and increased latency in both humans and animals whohave a genetic predisposition to alcohol use. To study the utility of the P300 as abiomarker for alcohol use disorders (AUDs), we examined its characteristic in alcoholpreferring (P) and non-preferring (NP) rats naïve to …