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University of Arkansas, Fayetteville

2013

Poultry Science

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Compositions And Methods Of Enhancing Immune Responses, Walter G. Bottje, Billy M. Hargis, Luc Berghman, Young M. Kwon, Kimberly Cole, Mandy Cox, Sherryll Layton Dec 2013

Compositions And Methods Of Enhancing Immune Responses, Walter G. Bottje, Billy M. Hargis, Luc Berghman, Young M. Kwon, Kimberly Cole, Mandy Cox, Sherryll Layton

Patents Granted

Salmonella enteritidis 13A strains and compositions comprising these strains are provided. Methods of enhancing an immune response against Influenza A; of reducing morbidity associated with an Influenza A infection; of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD 154 capable of binding CD40; of developing a bacterial vaccine vector are disclosed, and of generating scarless site-specific mutations in a bacterium are disclosed.


Method For Bacteriophage Delivery And Amplification, Billy M. Hargis, Stacy E. Higgins, Lisa R. Bielke, Guillermo L. Tellez, Lisa A. Newberry, Gerardo Nava, Ann M. Donoghue, Daniel J. Donoghue Feb 2013

Method For Bacteriophage Delivery And Amplification, Billy M. Hargis, Stacy E. Higgins, Lisa R. Bielke, Guillermo L. Tellez, Lisa A. Newberry, Gerardo Nava, Ann M. Donoghue, Daniel J. Donoghue

Patents Granted

Methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected are described. In addition to methods of treating a subject infected with a pathogenic bacterium using bacteriophage, of decontaminating objects using bacteriophage, of producing vaccines. In another aspect, methods of determining bacterial viability and methods of improving the sensitivity of a biosensor using wide host range bacteriophages are also disclosed.