Digital Commons Network^™

Design And Analysis Of Flexible Insulated Pavement For Cold Region Applications, Zhuang Zhuo

Theses and Dissertations

Pavements in cold regions suffer from additional deterioration due to the influences of extreme climate on frost-susceptible subgrade layers. To address this problem, one efficient strategy is to add a thermal insulating layer above the frost-susceptible layer. This study aims to evaluate the insulating effects of four materials: XPS boards, tire chips, foamed glass aggregates, and foamed concrete. Large-scale insulated pavement boxes (1.2m×1.2m×0.8m) were constructed to compare the thermal performance of different materials. The thermal performance of each box was evaluated and graded based on indicators related to the short-term temperature decrease and long-term temperature variation.

Experimental results show that …

Enhancing Situational Awareness For Rotorcraft Pilots Using Virtual And Augmented Reality, Ardit Pranvoku

Theses and Dissertations

Rotorcraft pilots often face the challenge of processing a multitude of data, integrating it with prior experience and making informed decisions in complex, rapidly changing multisensory environments. Virtual Reality (VR), and more recently Augmented Reality (AR) technologies have been applied for providing users with immersive, interactive and navigable experiences. The research work described in this thesis demonstrates that VR/AR are particularly effective in providing real-time information without detracting from the pilot's mission in both civilian and military engagements. The immersion of the pilot inside of the VR model provides enhanced realism. Interaction with the VR environment allows pilots to practice …

Placing Value On Environmental Literacy: A Case Study Of Biology Faculty Experiences, Ilene Sigrid Eberly

Theses and Dissertations

The purpose of this case study was to explore how contingent biology instructors place value on environmental literacy in their instruction and the instructional strategies used to foster their student's environmental literacy. This study also investigated the contextual experiences of contingent instructors influencing the value they place on environmental literacy. Participants included 11 faculty teaching introductory biology courses from two public universities in the Northeast. Our analysis focused on triangulation of participants semi-structured interviews, instructor-generated artifacts, and field notes from classroom observations, interviews, and artifacts. Findings revealed contingent biology instructors understand the importance of placing value on environmental literacy in …

Integrating The Funds Of Knowledge To Impact The Literacy Learning Experience For Students With Disabilities, Stephanie Lyn Losasso

Theses and Dissertations

The purpose of this study was to examine the impact on the literacy learning experience for students with disabilities when integrating the funds of knowledge into the curriculum. Prior to this research, students were given books with no relevance to their at home literacy. The curriculum was missing components of a framework that included the sociocultural perspectives of diverse learners. The participants for this study were three eight year old students. Two of the students were males and the one student was a female. The study was conducted during a 30-minute pull-out reading support. The students were interviewed to gain …

Factors Influencing Latina Healthcare System Distrust, Anthony D. Eldridge

Theses and Dissertations

The Latino community's healthcare engagement continues to be a growing national concern (Velasco-Mondragon et al., 2016). Due to sociocultural circumstances and racial marginalization, Latinas experience disproportionate health disparities and inequalities that may be exacerbated by healthcare system distrust (HSD) (Hacker et al., 2015). Ethnic identity, an established protective factor in Latino culture, may contribute to healthcare system distrust (Ai et al., 2012). Additionally, immigration status has been shown to negatively influence Latino's healthcare experiences leading to HSD (Luque et al., 2018). The present study evaluated the influence of sociodemographic factors and ethnic identity on HSD among Latinas. Ethnic identity and …

Unsupervised Learning For Anomaly Detection In Remote Sensing Imagery, Husam A. Alfergani

Theses and Dissertations

Landfill fire is a potential hazard of waste mismanagement, and could occur both on and below the surface of active and closed sites. Timely identification of temperature anomalies is critical in monitoring and detecting landfill fires, to issue warnings that can help extinguish fires at early stages. The overarching objective of this research is to demonstrate the applicability and advantages of remote sensing data, coupled with machine learning techniques, to identify landfill thermal states that can lead to fire, in the absence of onsite observations. This dissertation proposed unsupervised learning techniques, notably variational auto-encoders (VAEs), to identify temperature anomalies from …

Investigation Of Distracted Driving Events In New Jersey, Ahmed Sajid Hasan

Theses and Dissertations

Every year, thousands of people die in the United States due to crashes involving distracted driving, with this cause contributing to 25% of all fatal traffic crashes in New Jersey in particular. Over the past several years, various techniques (e.g., surveys, crash reports, videos, and simulations) were developed and implemented by the transportation safety community to identify and evaluate distracted driving events. However, these methods collect cross-sectional data on individual subjects and do not provide the actual number of distractions on the road. To fill this gap, this study collected longitudinal data on distracted driving events in the state of …

Delivery Optimization And Evaluation Of Biomechanics Of An Injectable Nucleus Pulposus Replacement Device, Zachary Rustin Brown

Theses and Dissertations

Lower back pain effects up to 80% of people at some point in their life, a majority of cases being the result of degenerative disc disease. Treatment options for degenerative disc disease are limited, jumping from physical therapy to major spinal fusion and total disc replacement surgery with little to no approaches in between. Furthermore, surgical treatments have not shown to be more effective than conservative treatments and reducing pain and disability over the long term. Hydrogels have shown promise as a potential nucleus pulposus replacement device. Their properties are controllable and can be implanted into the body through minimally …

Behavioral Effects Of Novel Treatments For Pain And Alcohol Use Disorder, Christa Marie Donegan

Theses and Dissertations

Opioid use disorder (OUD) and alcohol use disorder (AUD) are pressing public health problems in the United States that require new pharmacotherapies to be explored. Current FDA-approved treatment options for these two disorders are only moderately effective. Thus, there is a demand for the identification of new targets for drug development. Previous research initiatives have shown that when morphine is co-administered with the novel imidazodiazepine, MP-III-024, synergistic effects in models of analgesia and antinociception are produced. Our research efforts were concerned with understanding if morphine in combination with MP-III-024 produced synergistic effects in measures of undesirable pharmacological responses: opioid side …

Identifying Inhibitors Targeting The Nonstructural Protein 15 And Main Protease Of Coronaviruses Using Molecular Docking And Molecular Dynamics Simulation, Nakoa Kristen Webber

Theses and Dissertations

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2020 has impacted daily life globally for over a year. While multiple vaccines have been authorized for emergency use and one oral medication has entered clinical trials, we are still seeking antiviral drugs for a long-term treatment for SARS-CoV-2 as well as other coronaviruses. Computational drug screenings of two SARS-CoV-2 protein target candidates are presented in this thesis: the nidoviral RNA uridylate-specific endoribonuclease (Nsp15) and the main protease (Mpro) of SARS-CoV-2. Nonstructural proteins of coronaviruses were selected as targets as they are more conserved across coronavirus strains than …

Improving Outcomes Assessment Through Silo Integration, Jeffrey Scott Harmon

Theses and Dissertations

The purpose of this action research study was to leverage the experiences and perceptions of academic administrators at Mountain State University to disrupt the negative aspects of silo-based decision-making within closing the loop assessment practices. Siloed operations naturally begin to operate in contradiction to one another and often to the detriment of the organization. Focusing specifically on siloed operations across academic schools at Mountain State University, this study reveals issues of inefficiency and redundancy, and develops intervention strategies in an effort to improve closing the loop assessment efforts. These strategies include structural changes leading to a more integrated assessment model …

Fabrication And Comparative Study Of Horizontal And Vertical Electrospun Protein-Polysaccharide Nanofiber Biomaterials, Ashley Rivera-Galleti

Theses and Dissertations

The use of biocompatible and biodegradable composite materials for biomedical applications has attracted the attention of many researchers in the past few years. In this study, we fabricated nanofibers of silk fibroin and cellulose and its derivatives to amalgamate their unique properties into a single material. The production of these nanofibers via electrospinning is of particular interest, and whereas several studies have been done on normal nanofibers, the formation of branched nanofibers is an exciting area not currently explored. Blend solutions are formed by dissolving silk and cellulose/cellulose acetate in formic acid separately and mixing to achieve the desired ratios. …

Design Of A Custom Digital Light Projection Printer For In-Situ Production Of Composites With Improved Thermomechanical Properties, Margaret Anne Gillan

Theses and Dissertations

This work seeks to improve upon the existing state-of-the-art for vat photopolymerization additive manufacturing; namely, producing in-situ composites that combine the precision and high-performance materials of the vat photopolymerization with the strength of fiber-reinforced polymer composites. A custom-designed digital light projection printer was designed and built for printing composites, which includes an automated fiber tape system to place woven E-glass fiber mats in-situ. To validate the performance improvement of composites versus the neat matrix, composites were fabricated on the custom printer with hand-placed fiber mats. A high-performance, dual-cure resin was used for these studies. The effect of layer height on …

On The Socialization Of Transfer Physics Majors Enrolled Within Upper-Division Physics Courses At Transfer Receiving Institutions: Qualitative Research, Patrick Lee Chestnut

Theses and Dissertations

A host of individual and institutional sociocultural factors mediate transfer physics students' socialization experiences at 4-year transfer receiving institutions. The purpose of this study is to understand how sociocultural factors mediate transfer physics students' socialization while participating in upper-division physics coursework at a 4-year public transfer-receiving university. This study, rooted in sociocultural constructivism, aimed to shape discussion of seven transfer physics students, six regular admit physics students, and a physics course instructor's experiences connected to physics studies that emerged from qualitative data. These data included student and faculty surveys, interviews, and classroom observations. Several key findings emerged. First, a multitude …

Does Decentering Mediate The Relationship Between Mindfulness And Stress And Anxiety?, Hana Hannah Lee

Theses and Dissertations

College students are stressed and unsuccessful efforts to cope can increase risk for poor mental health, including anxiety (American College Health, 2019). Research suggests mindfulness (Bamber & Schneider, 2016) and adaptive emotion regulation (Desrosiers et al. 2013b) can buffer against the deleterious effects of distress. Decentering, a mindful emotion regulation strategy (Chambers et al., 2009), is postulated to be a mechanism by which mindfulness can lead to better mental health (Shapiro et al. 2006). Specific facets of trait mindfulness, namely Nonjudging (NJ) and Nonreactivity (NR) (Mizera et al. 2016), are directly involved in regulating one's emotions, which can help reduce …

Investigation Of The Role Of Hydrophobic Amino Acids On The Structure-Activity Relationship In Ponericin L1 From Neoponera Goeldii, Nicholas Patrick Schifano

Theses and Dissertations

Due to the increase prevalence of antimicrobial resistance (AMR) antibiotic alternatives have been of great interest. Antimicrobial peptides (AMPs) and polymers like polymethacrylates that mimic AMPs are two non-traditional antimicrobial agents that have been investigated thoroughly over the years as a potential solution to the AMR problem. This study will further the understanding of the L1 peptide by investigating the role hydrophobic amino acids have on the antimicrobial activity. Biophysical and microbiological techniques were utilized to show that the L1 hydrophobic derivative showed enhanced binding to anionic lipid bilayers while maintaining low hemolytic activity. This study also elucidates the effect …

Rainbow Trapping Effect In 2d Axisymmetric Broadband Acoustic Energy Harvesters, Louis Alexander Gormley

Theses and Dissertations

Acoustic energy harvesters (AEHs) collect otherwise unused ambient acoustic waves for conversion into useful electrical energy. This promising technology has potential applications ranging from grid-independent electronics to structural health monitoring systems. AEHs capture specific acoustic frequencies of interest using structures with frequency-matched component geometries. Despite the multitude of potential geometries suitable for AEH structures, existing AEH research has predominantly focused on the acoustic wave trapping performance of unidimensional or linear bidimensional AEH structures.

This study intended to broaden AEH bandwidth and capture efficiency by investigating the acoustic rainbow trapping performance of a novel 2D axisymmetric AEH design. A Finite Element …

Engineering A High-Throughput Screening Platform For Assessing Developmental Neurotoxicity Throughout Head- Regeneration In Schmidtea Mediterranea, Johnathan James Morris

Theses and Dissertations

The increase in commercially used chemicals that are inadequately evaluated for safety and risk to development has created a reticent threat to human health. Addressing these deficiencies is compounded by limited methodologies to determine the etiology of exposure-related developmental neurotoxicity (DNT). Current means of assessing DNT are largely retrospective and limited by the expensive, time-consuming, and labor-intensive use of laboratory animal models, thereby motivating a global research effort to produce alternative chemical screening assays. In this work, we have developed a novel high- throughput platform that serves as a new tool to evaluate the effects of exogenous chemical exposure on …

Endeavors Toward Novel Synthetic Roadmaps In The Synthesis Of Pertinent Pharmacological Molecular Scaffold Moieties, Justin David Horgan

Theses and Dissertations

One of the main goals in the GML lab group is the development of novel, economical, and environmentally friendly organic methods for the synthesis of pharmacologically relevant molecular moieties. The most salient pieces of data to the GML lab group members, reading dependable organic journals, are finding organic moieties that are largely unexplored, finding organic moieties which various research groups are having difficulty synthesizing, and finding complex organic procedures to key organic structures that can be easily reduced, or reconstructed, into novel methods that are more economical and environmentally friendly. By looking at these unexplored molecules, as well as hard …

Design Of An Inexpensive Pvc Shock Tube For Educational Use, Brandon Edward Bergmann

Theses and Dissertations

Herein is described the design and function of a low-cost, easy-to-assemble, -operate, and -disassemble shock tube platform experiment that can generate shock waves approaching Mach 2 at maximum pressures of ~100 psig with a helium driver gas. The experiment uses several inexpensive (<$5), unamplified piezoelectric sensors attached to a multichannel oscilloscope to monitor the passage of key features of the flow (i.e., incident shock and reflected shock) through the tube, constructed from inexpensive and easy to work with schedule 40 PVC pipe and fittings. From the fixed sensor displacements along the tube and relative differences in respective transit times, the velocities of these flow features can be determined. This permits (1) comparison of experimental results to the theoretical predictions of 1-D transient gas dynamics and (2) a leaping off point for discussion and quantification of non-idealities in the flow, including the shock wave development length, shock attenuation and boundary layer growth, and interactions of the reflected shock and contact surface. Experimental accessories (future work) for study of shock focusing and steady 2-D high speed flows are also briefly discussed. Assuming both pressurized, conditioned air at ~80-100 psig and a modern multi-channel oscilloscope are available at most institutions, the total cost to construct this experiment is around $500.

The Mediating Role Of Interpersonal Skills In The Relationship Between Depressive Symptomatology And Dating Violence In Young Mothers, Lauren Catherine Wallace

Theses and Dissertations

Young mothers are an understudied group at high-risk for dating violence (DV) victimization and perpetration. Psychological distress, such as depression, increases young mothers' risk for DV (Thomas et al., 2019). In turn, depressive symptomology is associated with difficulties in interpersonal competence (Jones et al., 2019), which may increase DV risk (Bonache et al., 2017). In addition, young mothers may have few chances to learn the interpersonal skills associated with healthy adult romantic relationships due to a mismatch in developmental level and parenting status (Herrman et al., 2019; Moore et al., 2007). Using interpersonal stress generation theory (Hammen, 1991, 2006), we …

Personal And/Or Vicarious Experience With Cancer As A Predictor Of Physical Activity: Moderating Effects Of Gender And Risk Perception, Pierre Alexander Leon M.A.

Theses and Dissertations

Background: Few studies have addressed the relationship between an individual's type of experience with cancer and its relationship with physical activity (PA). Furthermore, studies have not addressed gender and risk perception's ability to moderate the relationship between cancer experience and physical activity. To address this gap in understanding modifiable factors that might help or hinder PA levels, the overarching goal of this study is to: (a) estimate the degree to which an individual's experience of cancer effects PA levels, (b) determine how strongly gender moderates the relationship between the experience of cancer and PA levels, and (c) determine how strongly …

The Exploration Of Novel Synthetic Methods Of Biologically Relevant Nitrogen And Halogen Containing Molecules, Rebekah Erin Strong

Theses and Dissertations

Visible light has become a highly useful, and regarded, tool to the organic chemist. The additions and transformations of an abundance of molecules can be achieved with the use of visible light and photocatalysts, when appropriate. More specifically compounds that contain nitrogen, halogens, or both are highly useful structures in nearly every chemical industry. They are elements found in naturally occurring molecules and have the capacity to mimic biologically active and relevant structures. This makes them useful targets for pharmaceutical compounds. Bromine and chlorine can act as leaving groups; this property makes molecules with these elements reactive and thus able …

Protein-Based Nanofibers And Thin Films For Drug Delivery Applications, Christopher R. Gough

Theses and Dissertations

Corn zein and silk are both widely available, easy to extract proteins making them valuable replacements for synthetics. Zein and silk are also promising biomaterials in several applications. This work explores the use of both proteins as drug delivery vehicles by loading 1-Dimensional micro-nanofibers and 2-Dimensional thin films with model drugs or the topical therapeutic sodium citrate. Using a formic acid solvent, powdered zein protein or silk fibers were dissolved into solution and then casted into 2D films or spun into 1D fibers through air-spraying. During dissolution, therapeutic products are added. SEM images showed that fibers maintain their small diameter …

An Examination Of The Influence Of Distillation On The Combustion Behavior Of Apparently Equivalent Surrogate Fuels, Jay A. Lefkowitz

Theses and Dissertations

Use of surrogates to emulate the combustion behaviors of prevaporized real fuels has been widely demonstrated in the literature. However, many combustion applications utilize atomized fuel sprays, and for these configurations, the assumption of fuel property homogeneity in prevaporized fuel combustion is tenuous. This work uses a simplified distilling droplet model to demonstrate a real potential for vaporization-coupled deviations from the single-valued combustion property targets used to characterize prevaporized combustion behaviors. To verify the model-based observations, flame blowout measurements from a custom-built annular spray burner rig are measured. Sets of essentially equivalent prevaporized jet fuel and gasoline surrogates suggested in …

Severe Behavior And Restraint Use In A Hospital Setting For Patients With Autism Spectrum Disorder, Giovanna L. Salvatore

Theses and Dissertations

Physicians in hospital settings are treating an increasing number of patients with autism spectrum disorder (ASD). The occurrence of severe behavior is heightened for patients with ASD in hospital settings. Restraint is a commonly cited strategy to manage severe behavior across hospital departments; however, research on physician management of severe behavior in patients with ASD across the lifespan is lacking. Our sample included 25 participants across three medical trainee focus groups and three physician interviews. We investigated their experiences with severe behavior management and restraint implementation in patients with ASD at an urban teaching hospital. Transcripts were thematically analyzed using …

Laboratory And Full-Scale Pavement Sections Testing For Evaluating Frost Action In Cold Regions, Dorin Papuc

Theses and Dissertations

A comprehensive laboratory testing plan was conducted as part of this project to select two frost-susceptible soils for use in constructing three full-scale test strips. A total of 16 soils were obtained from various suppliers in NJ and were evaluated to determine their frost-susceptibility. The evaluation included conducting sieve analysis, hydrometer analysis, and specific gravity. Using these measures, two soils were selected (namely, Soil #2 and Soil #13) for constructing the test strips. The properties (Atterberg Limits, moisture-density relationships, California bearing ratio (CBR), Resilient Modulus among others) were determined through a laboratory testing plan. In addition, this study involved constructing …

Optimization Of Load-Bearing And Impact Energy Absorption Capacities Of Honeycomb Structures By Density Gradation, Oyindamola Khadijat Rahman

Theses and Dissertations

Density gradation has been analytically and experimentally proven to enhance the load-bearing and energy absorption efficiency of cellular solids. This research focuses on the analytical optimization (by virtual experiments) of polymeric honeycomb structures made from flexible thermoplastics to achieve density-graded structures with desired mechanical properties. The global stress-strain curves of single-density honeycomb structures are used as input to an analytical model that enables the characterization of the constitutive response of density-graded hexagonal honeycombs with discrete and continuous gradations and for various gradients. The stress-strain outputs are used to calculate the specific energy absorption, efficiency, and ideality metrics for all density-graded …

Computational Study Of Drug Interactions Of Receptors, Specifically Glycoprotein D Of Human Herpes Virus 1 And Dopamine D4 Receptor, Griffin Fountain

Theses and Dissertations

This thesis introduces computer-aided drug design methods in Chapter 1 and discuss their applications on two receptors in Chapters 2 and 3: Glycoprotein D (gD) of Herpes Simplex Virus 1 (HSV-1) and Dopamine Receptor D4 (DRD4). The Herpes Simplex Virus is a human pathogen that develops unpleasant cold sores around the body, most commonly around the mouth, neck or genitals area. Currently there is no cure or vaccine that can eliminate this virus. Glycoprotein D (gD) is a viral ligand for host cell receptors such as nectin -1. This interaction mediates the entry of HSV-1. In chapter 2, we used …

The Work Of Their Hands: Black Women And Critical Visionary Pragmatism, Natoya D. Coleman

Theses and Dissertations

This study examined the leadership principles, practices, and perspectives of Black women principals serving schools that are populated by primarily Black students. A portraiture of the participants' description of their racial and gender identities was conducted using kitchen table talks, to understand how identity development informed their leadership choices. Through the lens of Critical Race Feminism, Black Feminist Pedagogy, and Visionary Pragmatism, I highlight practices that lend to the development of a theoretical focus that speaks directly to the leadership practices of these Black women working in schools that serve Black student populations: Critical Visionary Pragmatism. Findings illuminate the ways …