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Examining The Urban Heat Island Effect In Albany, Ny Using Remote Sensing And Gis Techniques, Zhaoxin Ma May 2024

Examining The Urban Heat Island Effect In Albany, Ny Using Remote Sensing And Gis Techniques, Zhaoxin Ma

Undergraduate Honors Theses

This research delves into the complex dynamics of the Urban Heat Island (UHI) effect within the urban landscape of Albany, New York, employing advanced remote sensing and Geographic Information Systems (GIS) methodologies. With a primary focus on two interconnected objectives, this study attempts to unravel the spatial patterns of temperature extremes and assess associated vulnerabilities within communities, while also exploring the influence of green space distribution on the intensity of urban heat islands. The first objective examines temperature extremes' spatial distribution and vulnerability among demographic groups such as race/ethnicity, age, and income. It examines whether marginalized communities bear a disproportionate …


Investigating The Role Of Tryptophan In The Native Photo-Crosslinking Of A Cys-Containing Transmembrane Helix To A Membrane Lipid Double Bond, Michael Jay Telehany Apr 2024

Investigating The Role Of Tryptophan In The Native Photo-Crosslinking Of A Cys-Containing Transmembrane Helix To A Membrane Lipid Double Bond, Michael Jay Telehany

Undergraduate Honors Theses

Our research group has previously discovered that a Cys residue within a transmembrane (TM) helix can directly photo-crosslink to a membrane lipid via an oxythiolation addition reaction to the double bond within the lipid, with a reaction yield of 10-20%. The pH-low Insertion Peptide (pHLIP) serves as our model TM helix, while the POPC lipid bilayer is our model membrane. We had long believed that the Trp residues within the sequence of pHLIP served as the key chromophore for this reaction, and thus they were essential for the formation of the TM helix-lipid adduct. To test this hypothesis, I synthesized …


Interactions Between Adolescent Alcohol Consumption, Corticosterone, And Later Stress Sensitivity, Ariana L. Velazquez Apr 2024

Interactions Between Adolescent Alcohol Consumption, Corticosterone, And Later Stress Sensitivity, Ariana L. Velazquez

Undergraduate Honors Theses

Adolescence is characterized by many socio-emotional and neurobiological changes that often coincide with increased amounts of stress and the onset of alcohol use. Stress has been known to modulate alcohol intake, although the literature regarding this directionality is mixed. Both alcohol and stress can have lasting impacts on HPA axis activation (alterations in stress reactivity) and neuroimmune function (microglial sensitization). It has yet to be evaluated how concurrent ethanol and stress (recapitulated through oral corticosterone (CORT) administration) modulates alcohol intake and impacts later stress sensitivity and microglial sensitization. It was hypothesized that chronic concurrent ethanol and CORT drinking would (1) …


Ethanol-Induced Alterations To Astrocytic Glutamate Transporter Mrna Expression In The Mpfc Of Adult Mice, Zachary Evans Apr 2024

Ethanol-Induced Alterations To Astrocytic Glutamate Transporter Mrna Expression In The Mpfc Of Adult Mice, Zachary Evans

Undergraduate Honors Theses

The medial prefrontal cortex (mPFC) is one of several brain structures that is contained in the mesolimbocortical pathway and controls many processes involved in alcohol use disorder (AUD). There is vast glutamatergic output from the mPFC to other mesolimbocortical regions; neuroplastic changes to this system are believed to be closely tied to the development and maintenance of AUD. Astrocytes are key regulators of glutamatergic transmission through their uptake of excess glutamate from the synapse and recycling back into neurons. Ethanol (EtOH) alters the expression of astrocytic genes that encode for transporters that control glutamate homeostasis; these include the glutamate transporter-1 …


A Compendium Of Cross-Culturally Valid Intimate Partner Violence Assessment Items For North American Spanish Speakers, Alberto D. Torres-Aragón Apr 2024

A Compendium Of Cross-Culturally Valid Intimate Partner Violence Assessment Items For North American Spanish Speakers, Alberto D. Torres-Aragón

Undergraduate Honors Theses

Intimate partner violence (IPV) is physical, psychological, or sexual abuse by a current or former romantic partner. The long- and short-term consequences can lead to severe repercussions. To prevent these consequences of IPV, we need to screen for it and assess it. Across cultures, IPV is present and should be assessed regardless of linguistic boundaries. Spanish is the most widely used language in the U.S. other than English; therefore, assessment instruments that can reliably capture IPV in Spanish are necessary. Although Spanish-language IPV instruments are available, they may be challenging to understand for Spanish speakers because of linguistic differences. In …


Effects Of Ethanol On Social-Induced Neural Activity In A Rat Model Of Autism Spectrum Disorder, Andrew Waldon Apr 2024

Effects Of Ethanol On Social-Induced Neural Activity In A Rat Model Of Autism Spectrum Disorder, Andrew Waldon

Undergraduate Honors Theses

The prevalency of autism spectrum disorder (ASD) in the United States is increasing, with current estimates at 1 in 36 children, over 1 in 46 in 2018. ASD is a neurobiological disorder often characterized by social impairments, and reports suggest individuals with ASD are more likely to use drugs and alcohol to self-medicate. The current study examined patterns of neural activity in vehicle and ethanol-exposed adult rats that were previously exposed to valproic acid in utero, a well-defined ASD-like animal model. We report analyses of neural activity in tissue from transgenic cFos-LacZ rats in which a colorimetric histochemical enzymatic reaction …