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Psychology

Rats

2008

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Just Say “Nootropic”: The Effects Of Nicotine On Memory And Learning, Elyse N. Goveia May 2008

Just Say “Nootropic”: The Effects Of Nicotine On Memory And Learning, Elyse N. Goveia

Psychology Honors Papers

This study investigated the effects of nicotine on memory and learning in adolescent and adult male Fischer-344 rats. Rats were given 0.2 mg/kg/day of either nicotine or saline chronically for 2 weeks and were tested in the Morris water maze as adolescents (Phase 1) and then again 4 months later as adults (Phase 2). There were 4 main groups: nicotine/nicotine, nicotine/saline, saline/nicotine, and saline/saline. In Phase 2 rats were tested for c-Fos and BrdU expression in the dentate gyrus of the hippocampus. Behavioral data indicated that as adults, rats given nicotine were significantly improved at the water maze task compared …