Digital Commons Network^™

192 Igg-Saporin Lesions Of The Nucleus Basalis Magnocellularis Impair Serial Reversal Learning In Rats, Sara Michelle Cabrera

Theses Digitization Project

In order to assess flexibility in acquiring and using conflicting response rules, rats with selective lesions of the NBM or sham-lesion controls were subjected to serial reversal training in a simple operant discrimination paradigm. The NBM lesion group did not differ from the control group in acquisition of the original rules; the NBM lesion group required more time to master the changes in rules in the first reversal, but not in subsequent reversals.