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2020

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Decomposing Differences In Coronavirus Disease 2019-Related Case-Fatality Rates Across Seventeen Nations, Ashley Wendell Kranjac, Dinko Kranjac Dec 2020

Decomposing Differences In Coronavirus Disease 2019-Related Case-Fatality Rates Across Seventeen Nations, Ashley Wendell Kranjac, Dinko Kranjac

Sociology Faculty Articles and Research

As of 1 November 2020, estimated case-fatality rates associated with coronavirus disease 2019 are not uniformly patterned across the world and differ substantially in magnitude. Given the global spatial heterogeneity in case-fatality rates, we applied the Blinder-Oaxaca regression decomposition technique to identify how putative sociodemographic, structural, and environmental sources influence variation in case-fatality rates. We show that compositional and associational differences in country-level risk factors explain a substantial proportion of the coronavirus disease 2019-related case-fatality rate gap across nations. Asian countries fair better vis-à-vis case-fatality rate differences mainly due to variation in returns to sociodemographic, structural, and environmental sources among …


Coronavirus Update 12-22-20, The Coronavirus Planning Team Dec 2020

Coronavirus Update 12-22-20, The Coronavirus Planning Team

University Briefings & Virtual Events

We are excited to share that Sacred Heart has been contacted by the state of Connecticut about submitting names for the first phase of vaccination.


Coronavirus Update 12-18-2020, The Coronavirus Planning Team Dec 2020

Coronavirus Update 12-18-2020, The Coronavirus Planning Team

University Briefings & Virtual Events

As we conclude the semester, the dashboard shows us with 63 active cases. During the break, we will be updating the dashboard weekly on Thursdays. We will go back to daily updates once we are back on campus for spring.


Spring Update: Dear Faculty, Rupendra Paliwal Dec 2020

Spring Update: Dear Faculty, Rupendra Paliwal

University Briefings & Virtual Events

A message is forthcoming from the Coronavirus Planning Team regarding the plans for our return for the spring semester. We are planning a phased-in move-in process that will heavily emphasize mandatory testing.


Coronavirus Update 12-15-20, The Coronavirus Planning Team Dec 2020

Coronavirus Update 12-15-20, The Coronavirus Planning Team

University Briefings & Virtual Events

We want to share our plan for our return for the spring semester. This plan builds on our successes from the fall semester and incorporates lessons learned.


Students Continue Outreach Virtually During The Pandemic, Office Of Volunteer Programs & Service Learning Dec 2020

Students Continue Outreach Virtually During The Pandemic, Office Of Volunteer Programs & Service Learning

University Briefings & Virtual Events

Sacred Heart University students have been able to carry on their engagement in community service during the pandemic, thanks to the efforts of staff in the Office of Volunteer Programs & Service Learning (VPSL).


Analyses Of The 2020 Nobel Prize In Physiology Or Medicine: Taking The Hepatitis C Virus From Mystery Killer To Preventable And Treatable Disease, Neyda V. Gilman Dec 2020

Analyses Of The 2020 Nobel Prize In Physiology Or Medicine: Taking The Hepatitis C Virus From Mystery Killer To Preventable And Treatable Disease, Neyda V. Gilman

Library Scholarship

Harvey J. Alter, Michael Houghton, and Charles M. Rice share the 2020 Nobel in Physiology or Medicine for their contributions to the identification, treatment, and eventual elimination of the hepatitis C virus (HCV). The then novel molecular techniques they used have laid the groundwork for future work on HCV and other viruses. This article will give a brief overview of the hepatitis disease and the work of this year's laureates. It will also take a bibliometric look at the scientist’s research and add to the discussions about the way modern science is done and the limitations of prestigious science awards …


Message From Dr. Petillo 12/11/20, The Coronavirus Planning Team, John J. Petillo Dec 2020

Message From Dr. Petillo 12/11/20, The Coronavirus Planning Team, John J. Petillo

University Briefings & Virtual Events

Well, it certainly has been an unusual year. They say that every cloud has a silver lining. The silver lining for me in all that we have fought through this semester is YOU. This year has reinforced in a big way what I already knew about you—you care about others and SHU’s mission and values; you are resilient and adaptable; you are creative and find new ways to overcome challenges; you are hard-working and determined in the face of adversity; you are Pioneers in every sense of the word. And, when I say YOU, I am talking about every single …


Knowledge, Attitudes, And Practices Against The Growing Threat Of Covid-19 Among Medical Students Of Pakistan, Khola Noreen, Zil-E Rubab, Muhammad Umar, Rehana Rehman, Mukhtiar Baig, Fizzah Baig Dec 2020

Knowledge, Attitudes, And Practices Against The Growing Threat Of Covid-19 Among Medical Students Of Pakistan, Khola Noreen, Zil-E Rubab, Muhammad Umar, Rehana Rehman, Mukhtiar Baig, Fizzah Baig

Department of Biological & Biomedical Sciences

Background: On account of the COVID-19 pandemic, many changes have been implicated in university medical students. We are cognizant that pandemic can be controlled with dedicated contributions from all involved in the healthcare profession. Therefore, it is important to know the pandemic and application of knowledge by the medical students to formulate a further line of management in Pakistan.
Objective: We aimed toinvestigate the knowledge, attitudes, and practices (KAP) regarding COVID-19 and its impact on medical students of Pakistan.
Methods: A cross-sectional survey was conducted in June 2020 by a validated self-administered questionnaire. The survey instrument was tailored from a …


Knowledge, Attitudes And Practices Towards Covid-19 Among Pakistani Residents: Information Access And Low Literacy Vulnerabilities, Zafar Fatmi, Shafaq Mahmood, Waqas Hameed, Ibtisam Qazi, Muhammad Siddiqui, Anny Dhanwani, Sameen Siddiqi Dec 2020

Knowledge, Attitudes And Practices Towards Covid-19 Among Pakistani Residents: Information Access And Low Literacy Vulnerabilities, Zafar Fatmi, Shafaq Mahmood, Waqas Hameed, Ibtisam Qazi, Muhammad Siddiqui, Anny Dhanwani, Sameen Siddiqi

Community Health Sciences

Background: Coronavirus disease (COVID-19) has accentuated the need for speedy access to information. Digital divide and socio-demographic disparity create an information hiatus and therefore unhealthy practices with regard to dealing with COVID-19, particularly in low- and middle-income countries.
Aims: We assessed knowledge, attitudes, practices and their determinants regarding COVID-19 in Pakistan during March-April 2020.
Methods: 905 adults ≥18 years (males and females) participated: 403 from a web-based survey; 365 from an urban survey; and 137 from a rural survey. Frequency of adequate knowledge, attitudes and practices for the three populations was determined based on available global guidelines. Multivariable logistic regression …


Retrospective Review Of Anticoagulation Regimens Used For The Prevention Of Venous Thromboembolisms In Critically Ill Patients Infected With Sars-Cov-2, Tony Nguyen, Heidi Clarke Dec 2020

Retrospective Review Of Anticoagulation Regimens Used For The Prevention Of Venous Thromboembolisms In Critically Ill Patients Infected With Sars-Cov-2, Tony Nguyen, Heidi Clarke

All Publications

No abstract provided.


An Overview Of The Effect Of Bioaerosol Size In Coronavirus Disease 2019 Transmission, Marcelo I. Guzman Dec 2020

An Overview Of The Effect Of Bioaerosol Size In Coronavirus Disease 2019 Transmission, Marcelo I. Guzman

Chemistry Faculty Publications

The fast spread of coronavirus disease 2019 (COVID-19) constitutes a worldwide challenge to the public health, educational and trade systems, affecting the overall well-being of human societies. The high transmission and mortality rates of this virus, and the unavailability of a vaccine or treatment, resulted in the decision of multiple governments to enact measures of social distancing. Such measures can reduce the exposure to bioaerosols, which can result in pathogen deposition in the respiratory tract of the host causing disease and an immunological response. Thus, it is important to consider the validity of the proposal for keeping a distance of …


Ua94/6/1 Covid-19 Diary, Daniel Myers Dec 2020

Ua94/6/1 Covid-19 Diary, Daniel Myers

Student/Alumni Personal Papers

COVID-19 diary submitted to WKU Archives by student Daniel Myers for fall semester 2020.


Evaluation Of Incidence Of Thrombosis And Bleeding In Medical Floor Covid-19 Patients At A Community Hospital, Giselle Chahili, Frank C. Moreno Exposito, Heidi Clarke, Erika Dittmar Dec 2020

Evaluation Of Incidence Of Thrombosis And Bleeding In Medical Floor Covid-19 Patients At A Community Hospital, Giselle Chahili, Frank C. Moreno Exposito, Heidi Clarke, Erika Dittmar

All Publications

No abstract provided.


Ua94/6/1 Covid-19 Diary, Michaela Snyder Dec 2020

Ua94/6/1 Covid-19 Diary, Michaela Snyder

Student/Alumni Personal Papers

COVID-19 diary submitted to WKU Archives by student Michaela Snyder for fall 2020 semester.


Coronavirus Update 12-04-2020, The Coronavirus Planning Team Dec 2020

Coronavirus Update 12-04-2020, The Coronavirus Planning Team

University Briefings & Virtual Events

We are in the process of finalizing the plans for your return for spring and will share them with you before Christmas. As always, plans may change based on guidance from the state or the CDC and the prevalence of the virus locally and statewide.


Molecular Virology Of Kshv In The Lymphocyte Compartment—Insights From Patient Samples And De Novo Infection Models, Farizeh Aalam, Jennifer Totonchy Dec 2020

Molecular Virology Of Kshv In The Lymphocyte Compartment—Insights From Patient Samples And De Novo Infection Models, Farizeh Aalam, Jennifer Totonchy

Pharmacy Faculty Articles and Research

The incidence of Kaposi’s sarcoma-associated herpesvirus (KSHV)-associated Kaposi Sarcoma has declined precipitously in the present era of effective HIV treatment. However, KSHV-associated lymphoproliferative disorders although rare, have not seen a similar decline. Lymphoma is now a leading cause of death in people living with HIV (PLWH), indicating that the immune reconstitution provided by antiretroviral therapy is not sufficient to fully correct the lymphomagenic immune dysregulation perpetrated by HIV infection. As such, novel insights into the mechanisms of KSHV-mediated pathogenesis in the immune compartment are urgently needed in order to develop novel therapeutics aimed at prevention and treatment of KSHV-associated lymphoproliferations. …


An Investigation Into The Response Of The Us And Eu5 To The Covid-19 Disease (Convergence Of Two Pandemics: Covid-19 And Ncds), Omar Hassan Dec 2020

An Investigation Into The Response Of The Us And Eu5 To The Covid-19 Disease (Convergence Of Two Pandemics: Covid-19 And Ncds), Omar Hassan

Publications and Research

In late December 2019, a coronavirus disease (COVID-19) was identified in Wuhan China. COVID-19 was a result of the novel severe acute respiratory syndrome coronavirus 2 (SARA-CoV-2), which has resulted in a worldwide sudden and substantial increase in hospitalizations for pneumonia with multiorgan disease. As of October 6, 2020, SARS-CoV-2 has affected more than 200 countries, resulting in more than 35 million identified cases with more than 1 million confirmed deaths.

This is a cross-sectional, non-interventional, observational study in patients infected with the novel coronavirus (SARS-CoV-2) or Covid-19, using John Hopkins University database JHU Coronavirus map. The data collected from …


An Update Of The Virion Proteome Of Kaposi Sarcoma-Associated Herpesvirus, Ramina Nabiee, Basir Syed, Jesus Ramirez Castano, Rukhsana Lalani, Jennifer Totonchy Dec 2020

An Update Of The Virion Proteome Of Kaposi Sarcoma-Associated Herpesvirus, Ramina Nabiee, Basir Syed, Jesus Ramirez Castano, Rukhsana Lalani, Jennifer Totonchy

Pharmacy Faculty Articles and Research

The virion proteins of Kaposi sarcoma-associated herpesvirus (KSHV) were initially characterized in 2005 in two separate studies that combined the detection of 24 viral proteins and a few cellular components via LC-MS/MS or MALDI-TOF. Despite considerable advances in the sensitivity and specificity of mass spectrometry instrumentation in recent years, leading to significantly higher yields in detections, the KSHV virion proteome has not been revisited. In this study, we have re-examined the protein composition of purified KSHV virions via ultra-high resolution Qq time-of-flight mass spectrometry (UHR-QqTOF). Our results confirm the detection of all previously reported virion proteins, in addition to 17 …


Covid-19 Viral Testing Disparities In Los Angeles City, Laura Cyphers Dec 2020

Covid-19 Viral Testing Disparities In Los Angeles City, Laura Cyphers

Student Scholar Symposium Abstracts and Posters

Hispanic and Black communities have been disproportionately impacted by COVID-19-related morbidity and mortality (California Department of Public Health, 2020). Inequitable access to viral testing resources may have exacerbated these COVID-19-related racial and ethnic health disparities. For example, reports from the Los Angeles Department of Public Health revealed glaring viral testing disparities in April 2020 (early pandemic), with predominantly White communities in Los Angeles County receiving 65% more tests than Hispanic and Black communities. In response, California statewide testing was expanded for communities of color (Vann et al., 2020). To investigate access to viral testing in Los Angeles City, the current …


The World On Pause: A Children's Book About Living During A Pandemic, Amanda Desmarais Dec 2020

The World On Pause: A Children's Book About Living During A Pandemic, Amanda Desmarais

Senior Honors Projects

Life as we now know it has drastically changed since March 2020. Over 60 million people throughout the world have been infected with COVID-19. Unfortunately, over a million have died from the virus in a short period of time. The last pandemic occurred in 1918, many years before most of us were born. Since the pandemic is a health crisis most generations have never experienced, adults and children alike are learning to cope simultaneously. It is difficult to teach children coping mechanisms during these chaotic and unfamiliar times. Family members can’t set positive examples if their coping techniques are inconsistent. …


Coronavirus Update 12-01-2020, The Coronavirus Planning Team Dec 2020

Coronavirus Update 12-01-2020, The Coronavirus Planning Team

University Briefings & Virtual Events

We want you to enjoy the holiday season, but we also want you to be safe and healthy, so we ask that you keep traveling to a minimum and that you continue to follow the Pioneer Promise while away from campus.


Leading Change During The Convergence Of An Epidemic And A Pandemic, Sarah Oerther, Daniel B. Oerther Dec 2020

Leading Change During The Convergence Of An Epidemic And A Pandemic, Sarah Oerther, Daniel B. Oerther

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

As the first wave of COVID-19 cases spread around the globe in early 2020, the healthcare community adopted a medical model that emphasized the use of resources to mitigate viral spread (Oerther & Watson, 2020). Schools, churches, and businesses shutdown, and healthcare facilities – from outpatient clinics to inpatient elective surgeries – were closed or cancelled. Even long-term care facilities, such as nursing homes, limited access of visitors to patients in an attempt at mitigation. And for six months, the healthcare community focused almost exclusively on a medical response to COVID-19, securing stockpiles of ventilators and fast-tracking vaccine development.


Imagining A Lean And Agile Digital Health Ecosystem - A Measure Of Pandemic Responsiveness, Zainab Samad, Sana Mahmood, Sameen Siddiqi, Zulfiqar Ahmed Bhutta Dec 2020

Imagining A Lean And Agile Digital Health Ecosystem - A Measure Of Pandemic Responsiveness, Zainab Samad, Sana Mahmood, Sameen Siddiqi, Zulfiqar Ahmed Bhutta

Section of Cardiology

No abstract provided.


Covid-19 Pandemic: Economic Burden On Patients With Musculoskeletal Injuries In A Tertiary Care Hospital Of Lmic; Retrospective Cross Sectional Study, Pervaiz Hashmi, Shah Fahad, Hammad Naqi Khan, Marij Zahid, Anum Sadruddin Pidani, Shahryar Noordin Dec 2020

Covid-19 Pandemic: Economic Burden On Patients With Musculoskeletal Injuries In A Tertiary Care Hospital Of Lmic; Retrospective Cross Sectional Study, Pervaiz Hashmi, Shah Fahad, Hammad Naqi Khan, Marij Zahid, Anum Sadruddin Pidani, Shahryar Noordin

Section of Orthopaedic Surgery

Covid-19 has adversely impacted the health care organizations by over burdening with Covid patients and suspending the elective surgeries and clinics. Hospitalization during pandemic may increase health cost of patients for elective and emergency procedure due to extra cost of covid testing and isolation. A single center retrospective study was conducted to quantify losses due to postponement of elective surgeries and extra cost for procurement of PPEs. The secondary objective was to see the effect of Covid -19 on the total costs of inpatient care during Covid era.
Patient and method: We included all the patients admitted in orthopedic section …


Rigorous Hand Hygiene Practices Among Health Care Workers Reduce Hospital-Associated Infections During The Covid-19 Pandemic, Rozina Roshan, Anam Shahil Feroz, Zohra Rafique, Nazleen Virani Dec 2020

Rigorous Hand Hygiene Practices Among Health Care Workers Reduce Hospital-Associated Infections During The Covid-19 Pandemic, Rozina Roshan, Anam Shahil Feroz, Zohra Rafique, Nazleen Virani

Section of Internal Medicine

The experiences of these recent months have left us with as many new questions as they have given us new solutions. The main question that infection prevention and control department is having these days is "Why have hospital-associated infections (HAIs) reduced during COVID-19 pandemic?" What is the one unique strategy that has brought decline in increasing HAIs? Would it be appropriate to say that rigorous hand hygiene practices among health care workers (HCWs) have reduced HAIs in a tertiary care hospital of Pakistan? This commentary is written to understand the effect of rigorous hand hygiene among HCWs on number of …


Change In The Spectrum Of Orthopedic Trauma: Effects Of Covid-19 Pandemic In A Developing Nation During The Upsurge; A Cross-Sectional Study, Pervaiz Mahmood Hashmi, Marij Zahid, Syed Arif Ali, Hammad Naqi Khan, Anum Sadruddin Pidani, Alizah Pervaiz Hashmi, Shahryar Noordin Dec 2020

Change In The Spectrum Of Orthopedic Trauma: Effects Of Covid-19 Pandemic In A Developing Nation During The Upsurge; A Cross-Sectional Study, Pervaiz Mahmood Hashmi, Marij Zahid, Syed Arif Ali, Hammad Naqi Khan, Anum Sadruddin Pidani, Alizah Pervaiz Hashmi, Shahryar Noordin

Section of Orthopaedic Surgery

Background: The COVID-19 pandemic has caused a great impact on orthopedic surgery with a significant curtailment in elective surgeries which is the major bread and butter for orthopedic surgeons. It was also observed that the spectrum of orthopedic trauma injuries has shifted from more severe and frequent road traffic accidents (high energy trauma) to general, low energy house-hold injuries like low energy fractures in the elderly, pediatric fractures, house-hold sharp cut injuries and nail bed lacerations. The aim of this study is to appraise the effect of the COVID-19 pandemic on orthopedic surgical practice, both inpatient and outpatient facility.
Materials …


Towards Pragmatic Adaptations: Orthopedic Surgery Amidst The Coronavirus Disease 2019 Pandemic, Maryam Ehtesham, Talal Almas, Muhammad Ali Niaz, Absam Akbar Dec 2020

Towards Pragmatic Adaptations: Orthopedic Surgery Amidst The Coronavirus Disease 2019 Pandemic, Maryam Ehtesham, Talal Almas, Muhammad Ali Niaz, Absam Akbar

Medical College Documents

No abstract provided.


Global Burden Of Acute Lower Respiratory Infection Associated With Human Metapneumovirus In Children Under 5 Years In 2018: A Systematic Review And Modelling Study, Xin Wang, You Li, Maria Deloria-Knoll, Shabir A. Madhi, Cheryl Cohen, Syed Asad Ali, Sudha Basne, Quique Bassat, W Abdullah Brooks, Malinee Chittaganpitch Nov 2020

Global Burden Of Acute Lower Respiratory Infection Associated With Human Metapneumovirus In Children Under 5 Years In 2018: A Systematic Review And Modelling Study, Xin Wang, You Li, Maria Deloria-Knoll, Shabir A. Madhi, Cheryl Cohen, Syed Asad Ali, Sudha Basne, Quique Bassat, W Abdullah Brooks, Malinee Chittaganpitch

Department of Paediatrics and Child Health

Background: Human metapneumovirus is a common virus associated with acute lower respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs associated with human metapneumovirus in children, and no licensed vaccines or drugs exist for human metapneumovirus infections. We aimed to estimate the age-stratified human metapneumovirus-associated ALRI global incidence, hospital admissions, and mortality burden in children younger than 5 years.
Methods: We estimated the global burden of human metapneumovirus-associated ALRIs in children younger than 5 years from a systematic review of 119 studies published between Jan 1, 2001, and Dec 31, 2019, and a further 40 high …


Coronavirus Update 11/24/20, The Coronavirus Planning Team Nov 2020

Coronavirus Update 11/24/20, The Coronavirus Planning Team

University Briefings & Virtual Events

One final message before the Thanksgiving weekend break to wrap up a few things.