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Multiple Antibiotic Resistant Staphylococcus Spp. In Environmental Settings, Stephen Shost Jan 2009

Multiple Antibiotic Resistant Staphylococcus Spp. In Environmental Settings, Stephen Shost

Legacy Theses & Dissertations (2009 - 2024)

Ninety staphylococci carrying the mecA gene, including 17 strains of methicillin-resistant Staphylococcus aureus (MRSA), were isolated from environmental settings within New York State. Waterborne staphylococci harboring mecA were isolated from multiple sources: the Hudson River near a combined sewage overflow; urban streams; freshwater and marine beaches; a swimming pool; swimming pool decks; combined sewage; as well as wastewater treatment plant (WWTP) primary sewage influent, mixed liquor, aeration water, and final (unchlorinated) effluent. Environmental MRSA strains were isolated from beach water (n=3); swimming pool deck water (n=1); Hudson River water (n=2); combined sewage (n=3); as well as wastewater treatment plant mixed …


Harm Reduction In Outpatient Drug-Free Substance Abuse Treatment Settings, Michael Eversman Jan 2009

Harm Reduction In Outpatient Drug-Free Substance Abuse Treatment Settings, Michael Eversman

Legacy Theses & Dissertations (2009 - 2024)

In the United States, drug-free substance abuse treatment programs generally operate under an abstinence-only, disease model based service orientation. Citing several reasons, critics suggest disease model approaches hinder client utilization and retention within such services. The framework of harm reduction offers an alternative approach to substance abuse treatment services and may have potential for improving utilization and retention outcomes. Yet little is known about how harm reduction is perceived by practitioners in drug-free substance abuse treatment settings, and the circumstances in which harm reduction may or may not be accepted. In addition, despite a body of narrative literature suggesting harm …


Identification Of B-Cell Epitopes On Domain 4 Of Anthrax Protective Antigen, Cassandra D. Kelly-Cirino Jan 2009

Identification Of B-Cell Epitopes On Domain 4 Of Anthrax Protective Antigen, Cassandra D. Kelly-Cirino

Legacy Theses & Dissertations (2009 - 2024)

Protective Antigen (PA) is the receptor binding subunit common to both Lethal (LT) and Edema (ET) toxins, which contribute to the mortality associated with Bacillus anthracis infection. While recombinant PA (rPA) is likely to be an important constituent of second generation anthrax vaccines, evaluating the effectiveness of candidate vaccines is currently difficult, because the specific B cell epitopes involved in toxin neutralization have not been completely defined. The only well characterized antibody, 14B7, has been shown to disrupt the association of PA with the anthrax toxin receptors (ATR) by binding to domain 4 of PA. I hypothesized that other domain …


Biomonitoring For Exposure To Trace Elements In Utero : Analysis Of The Human Placenta, Pamela Catherine Kruger Jan 2009

Biomonitoring For Exposure To Trace Elements In Utero : Analysis Of The Human Placenta, Pamela Catherine Kruger

Legacy Theses & Dissertations (2009 - 2024)

The placenta forms in eutherian mammals, and is responsible for the nutrition of the developing fetus. However, maternal exposure to environmental pollutants both before and during pregnancy may result in the passage of toxins through the placental barrier and into fetal tissues. The placenta is the only organ derived from both maternal and fetal tissues, and establishes a link between the fetus and the environmental exposures of the mother. The analysis of placentae for the presence of environmental pollutants offers the possibility of exposure measurements in both the mother and the developing fetus. Specifically, trace element determination in human placentae …


Infected Justice : The Impact Of Hiv/Aids On The Police In Anglo-Phone Sub-Saharan Africa, Nathan Carl Meehan Jan 2009

Infected Justice : The Impact Of Hiv/Aids On The Police In Anglo-Phone Sub-Saharan Africa, Nathan Carl Meehan

Legacy Theses & Dissertations (2009 - 2024)

Sub-Saharan Africa is an epicenter of the HIV/AIDS epidemic. This disease is affecting nearly every aspect of society in this region. This disease destroys individuals, strains family structures, weakens economies, burdens health systems, and can destabilize entire countries. The police are also being affected by HIV/AIDS. The way in which this disease impacts police organizations in sub-Saharan Africa is understudied. This project sought to estimate the HIV/AIDS impacts on police organizations in Anglo-phone sub-Sahara by utilizing the available literature on how HIV/AIDS affects military, civil service, healthcare, and education organizations in these same countries. It also attempts to identify the …