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Brain Structure In Older Adult Siblings, Nathaniel Lucena
Brain Structure In Older Adult Siblings, Nathaniel Lucena
All Theses and Dissertations (ETDs)
Considerable variability exists in patterns of brain aging within and across individuals. Quantifying familial contributions to brain structure in late life may help us understand this variability. We estimated heritability of gray and white matter volumes and cortical thickness in a sample of older adult full siblings: 2-4 individuals per pedigree; N = 75). Estimation of heritability was based on computation of intraclass correlations. Heritability estimates were higher for total cortical thickness compared to volumes. There was no evidence of overall laterality in heritability estimates, or differences between primary sensory and association regions. There was a tendency for lower estimates …
Sensory And Cognitive Declines In Older Adults: A Longitudinal Study, Melanie Storm Bauer
Sensory And Cognitive Declines In Older Adults: A Longitudinal Study, Melanie Storm Bauer
All Theses and Dissertations (ETDs)
In a recent cross-sectional study, as has been found in numerous previous studies, Sommers et al.: 2011) found that age-related declines in hearing, as assessed by pure-tone thresholds, begin around age 20 and continue across the lifespan. In another article published from the same cross-sectional dataset, Hale et al.: 2011) found that working memory ability also begins declining around age 20 and continues throughout life. The present study is a longitudinal follow-up of these two studies in which a sub-sample of older adults: ≥65 years old at the time of original testing approximately four years ago) were re-tested on sensory …