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The Technology Development And Commercialization Of 'Smart' Scientific Instrumentations, Tony Hoang

Legacy Theses & Dissertations (2009 - 2024)

The technology development of two centrifuge-based instruments gave rise to an Internet-of-Things (IOT) biotech startup. The first instrument: the centrifuge force microscope (CFM) was recently introduced as a platform for massively parallel single-molecule manipulation and analysis. Here we developed a low-cost and self-contained CFM module that works directly within a commercial centrifuge, greatly improving accessibility and ease of use. Our instrument incorporates research grade video microscopy, a power source, a computer, and wireless transmission capability to simultaneously monitor many individually tethered microspheres. Building off of the first project, the second instrument we introduced was the “smart” centrifuge-test tube holder. The …