Digital Commons Network^™

Popularity Prediction, Andrew Furgiuele

Computer Science

With the rise in popularity of the Internet, data describing unique types of items has been collected into easy to access sources. Using this newly acquired data, is it possible to predict if an item will become a bestseller while another fade away with time? Popularity prediction is a problem that has attracted a great deal of research recently, and for good reason. The ability to predict an items future rise to popularity or fall to obscurity is a possibly priceless skill and sought out in many different industries such as sales, investments, and marketing. This report enumerates and analyzes …

Informing Responders Using Gis And Gps, Deidre Mccarthy

CHAR

Hurricane Katrina devastated the Gulf Coast in August 2005 and created the single largest disaster for cultural resources that the United States has witnessed since the inception of the National Historic Preservation Act (NHPA) in 1966. Notably, the NHPA created the National Register of Historic Places, our nation’s catalog of important cultural resources. The NHPA also stipulates that any federal undertaking which may adversely affect National Register eligible resources be mitigated. For the Federal Emergency Management Agency (FEMA), Katrina created the largest compliance project ever under Section 106 of the NHPA.

Although causing a great deal of damage, Katrina also …

Keynote Address: Climate Change: From Global To New York Scale, Christopher D. Thorncroft

CHAR

This talk is concerned with the science and impacts of climate change from global to New York scales. It will provide an assessment of how the climate has changed over the past Century based on a purely observational perspective. The scientific basis for anthroprogenic climate change will be explained and discussed including a description of the “greenhouse effect” and why it is important for life on this planet. We will briefly discuss global and local consequences of a warmer climate and what we need to be prepared for going forward in the coming decades.

Review Of Principles Of Computer Science, Ed. By Donald R. Franceschetti., Michael Knee

University Libraries Faculty Scholarship

A review of "Principles of Computer Science" edited by Donald R. Franceschetti.

Irrational Eigenvalues Of The Discrete Laplacian: A Study Of Simplical Complexes, Brian Bollen

Psychology

We study the behavior of eigenvalues of the discrete Laplacian of an abstract simplicial complex K when subdividing a single face of K . We show that if K is a simplex, performing this kind of restricted subdivision twice on a single face produces irrational eigenvalues for the discrete Laplacian.

Design, Synthesis And Characterization Of New Analogs Of Tetraiodothyroacetic Acid (Tetrac) As Novel Angiogenesis Modulators And Their Binding Studies With Αvβ3 Integrin, Mary Adeyeye

Chemistry

Angiogenesis is the formation of new blood vessels from preexisting blood vessels. Design and development of novel angiogenesis inhibitors has been validated as a target in several tumor types. Integrins are important ligands that play a critical role in the angiogenesis process, particularly blood formation and local release of vascular growth factors, and they are members of a family of cell surface receptors. Tetraiodothyroacetic acid (tetrac), a deaminated derivative of thyroid hormone T4, is a thyroid antagonist and blocks the actions of T3 and T4 with an interaction site that is located at or near the RGD recognition site identified …

Differentiation Of Hair Using Atr Ft-Ir Spectroscopy: A Statistical Classification Of Dyed And Non-Dyed Hairs, Matthew S. Boll

Chemistry

Although hair is one of the most common and abundant types of evidence found at a crime scene, the current forensic analyses employed underutilize its full potential evidentiary value. Microscopy is the fundamental technique used to analyze forensic hair evidence, but even this routine and well-accepted method has limitations. In this study, non-dyed and dyed hairs from individuals varying in race, biological sex, and age, were analyzed using attenuated total reflection Fourier transform-infrared (ATR FT-IR) spectroscopy. Through the incorporation of multivariate statistical analysis, spectra collected from dyed and non-dyed hairs were differentiated with high accuracy. After hair spectra were determined …

Determining The Role Of Secondary Structure In Translational Control, Dhruv S. Patel

Chemistry

The central dogma of cellular biology asserts that DNA is transcribed to mRNA, which in turn is translated to a protein. This simplistic conduit of gene expression is heavily regulated at multiple levels to ensure proper temporal and spatial expression of genes. One such mode of regulation occurs at the juncture at which RNAs are translated to proteins, known as translational regulation. mRNAs can be translationally regulated by trans-acting factors, such as RNA binding proteins (RBPs), and/or cis-acting factors. Regulation via these two modalities can depend on structure as well as RNA sequence. Secondary structures, such as stem loops, are …

The Classical Limit Of Entropic Quantum Dynamics, Anthony V. Demme

Physics

The framework of entropic dynamics (ED) allows one to derive quantum mechanics as an application of entropic inference. In this work we derive the classical limit of quantum mechanics in the context of ED. Our goal is to find conditions so that the center of mass (CM) of a system of N particles behaves as a classical particle. What is of interest is that ~ remains finite at all steps in the calculation and that the classical motion is obtained as the result of a central limit theorem. More explicitly we show that if the system is sufficiently large, and …

Cooperation Between Top-Down And Low-Level Markov Chains For Generating Rock Drumming, Chris Caulfield

Computer Science

Without heavy modification, the Markov chain is insufficient to handle the task of generating rock drum parts. This paper proposes a system for generating rock drumming that involves the cooperation between a top - down Markov chain that determi nes the structure of created drum parts and a low - level Markov chain that determines their contents. The goal of this system is to generate verse - or chorus - length drum parts that sound reminiscent of the drumming on its input pieces.

Effects Of An Impaired Sonic Hedgehog Signaling Pathway And A Nonfunctional Gli3 Protein On Gnrh-1 Neuronal Migration In Gli3xt/Xt Mutants, Elizabet Aleks Genis

Computer Science

Gonadotropin releasing hormone (GnRH) is the master regulatory hormone for sexual development. During embryonic development, gonadotropin releasing hormone-1 neurons (GnRH-1ns) form in the olfactory pit and migrate, along axonal Peripherin positive fibers, from the nasal area to the pre-optic area of the basal forebrain. Upon migration into the brain, GnRH-1ns release GnRH. Defective migration of GnRH-1ns can result in hypogonadotropic hypogonadism (HH), a condition that results in lack of sexual development and infertility. When HH appears associated with reduced or absent sense of smell, it is clinically defined as Kallmann Syndrome (KS) (Paolo E Forni & Wray, 2015). The neurons …

High-Fidelity Spectrum Characterization With Low-Cost Sensors, Stuti Misra

Computer Science

With the increasing use of wireless technologies, we see a heavy use of the spectrum at certain frequencies whereas it is underutilized at other frequencies. We need to utilize the currently underutilized spectrum. Hence, a paradigm called Dynamic Spectrum Access arises. Dynamic Spectrum Access looks for opportunity to utilize this underutilized spectrum by allowing devices to opportunistically access spectrum that is not actively used. DSA, however, requires spectrum sensing and spectrum characterization across time, space, and frequency for opportunistic devices to know where to operate. Spectrum sensing is the process of collecting power level traces from the radio-frequency spectrum, whereas …

Raman Spectroscopy Capabilities Of The Cbex Handheld Raman Instrument, Samantha Ingenito

Chemistry

Raman spectroscopy is a reliable, nondestructive method of identifying and distinguishing between different types of biological fluids. However, forensic studies have been restricted to indoor desktop Raman instruments when it would be optimal if Raman spectroscopic analysis could be performed at a crime scene. The CBex Handheld Raman Instrument was developed as a portable tool that could perform Raman spectroscopy outside the lab. Unfortunately, the CBex cannot obtain viable spectra of biological fluids. The handheld was compared to the Renishaw invia Raman Microscope by quantifying the signal-to-noise ratio of each by acquiring Scotch tape spectra. The handheld has a significantly …

Assessing Sustainability Literacy, Mary Ellen Mallia, Cassidy Drasser, Elizabet Genis

Presentations

Presented for the US Society for Ecological Economics

Structure Formulas For Wave Operators Under A Small Scaling Invariant Condition, Marius Beceanu, Wilhelm Schlag

Mathematics and Statistics Faculty Scholarship

We obtain structure formulas for the intertwining wave operators of a Schroedinger operator with potential V in R^3. The difference from our previous submission arXiv:1612.07304 lies with the fact that here we impose a scaling invariant condition on the potential, albeit with a smallness requirement.

Structure Formulas For Wave Operators, Marius Beceanu, Wilhelm Schlag

Mathematics and Statistics Faculty Scholarship

We establish quantitative estimates on the structure function arising in the representation of the intertwining wave operators of a Schroedinger operator in three dimensions. Regularity of zero energy is assumed throughout. This paper is related to, and corrects some inaccuracies in, the first author's work this https URL

Computationally Efficient Multiple Imputation Routines In Clustered Data, Tugba Akkaya-Hocagil

Legacy Theses & Dissertations (2009 - 2024)

Presence of missing data in correlated data settings is a non-trivial problem. Inference by multiple imputation offers a viable solution to analysts. However, the missing data problem is typically more complicated due to diverse measurement scales, skip patterns, bounds and restrictions. Sequential regression imputation also known as variable-by-variable imputation has emerged as a popular imputation modeling technique, especially in the complex data structures. In this dissertation, we develop three methods to handle incomplete data in hierarchically nested and non-nested multilevel data structures using sequential regression imputation approach.

Torsion Freeness Of Symmetric Powers, Exterior Powers, And Schur Functors, Muberra Allahverdi

Legacy Theses & Dissertations (2009 - 2024)

Let $R$ be a local Noetherian commutative ring and $I$ an ideal with projective dimension less than or equal to 1. Necessary and sufficient conditions were provided in \cite{T2007} for a symmetric power $S_kI$ of an ideal of projective dimension 1 to be torsion free, where $k \geq 2$. We extend this result to symmetric powers and a broad class of Schur functors of finitely generated $R$-modules with projective dimension 1. While doing so, we also study the structure of Schur complexes from \cite{ABW1982}, and provide necessary and sufficient conditions for the acyclicity of the Schur complex by computing the …

Extension Properties Of Asymptotic Property C And Finite Decomposition Complexity, Susan Beckhardt

Legacy Theses & Dissertations (2009 - 2024)

We prove extension theorems for several geometric properties such as asymptotic property C (APC), finite decomposition complexity (FDC), straight finite decomposition complexity (sFDC) which are weakenings of Gromov’s finite asymptotic dimension (FAD).

Examining Variability In Model Skill During The 7 January 2013 Sudden Stratospheric Warming Event, Jonathan Lee Blufer

Legacy Theses & Dissertations (2009 - 2024)

Recent analyses of numerical weather prediction models have shown that stratospheric regime changes (e.g. strong and weak vortex events) are not skillfully predicted at medium-range lead times. Motivated by these recent analyses, this thesis investigates the sources of variability in stratospheric forecast skill amongst several operational models initiated at different lead times prior to the 7 January 2013 sudden stratospheric warming (SSW). This study extends upon a previous analysis by the Stratospheric Network for the Assessment of Predictability (SNAP), which concluded that a change in forecast lead-time from 15 to 10 days increased model skill in predicting the 2013 SSW …

Linkages Between Tropopause Polar Vortices And The Development Of Cold Air Outbreaks Over Central And Eastern North America, Kevin Biernat

Legacy Theses & Dissertations (2009 - 2024)

Coherent vortices in the vicinity of the tropopause, referred to as tropopause polar vortices (TPVs), may be extracted from high latitudes in conjunction with high-latitude upper-level ridge amplification. Once extracted, TPVs may interact with and strengthen midlatitude jet streams, as well as act as precursor disturbances for the development of intense midlatitude cyclones. Cold pools that may accompany TPVs as they are transported to middle latitudes may lead to widespread cold air outbreaks (CAOs), which may result in significant socioeconomic impacts. The purpose of this study is to investigate 1) the equatorward transport of TPVs and cold pools to middle …

Structural Characterization Of The Interactions Of Nicotinamide And Analogs With Human Sirt6 By Saturation Transfer Difference (Std) Nmr And Site Directed Mutagenesis, Beatriz Elena Bolivar-Vega

Legacy Theses & Dissertations (2009 - 2024)

The allosteric regulation of SIRT6 by nicotinamide (NAM), along with the growing evidence of this enzyme's key role in the immune response, prompted the mechanistic study of SIRT6 inhibition by pyrazinamide (PZA) and analogs. In our current study, PZA, an analog of NAM, was revealed to have a modest modulatory effect on SIRT6, an enzyme that regulates the NF-κB signaling pathway at the transcriptional level (a relevant pathway to inflammation). Similarly, the analogs of PZA, 5-Cl PZA, 5-MeO PZA, and POA exhibited a modulatory effect against SIRT6 in our in vitro studies, enabling identification of a potential new target for …

On Combinatorial Models For Kirillov-Reshetikhin Crystals Of Type B, Carly Jean Anderson Briggs

Legacy Theses & Dissertations (2009 - 2024)

KR crystals encode the structure of certain finite dimensional representations of affine Lie algebras. There are various combinatorial models for them; type specific ones, such as tableau models in classical types and type independent ones, such as the quantum alcove model. While the type specific models are more explicit, they have less easily accessible information, so it is generally hard to use them in specific computations. As these computations are much simpler in the quantum alcove model, an alternative is to translate them to the tableau models, via a crystal isomorphism between the two models. This was achieved in types …

Bounded Algebra Over Coarse Spaces, Patrick Cahill

Legacy Theses & Dissertations (2009 - 2024)

Bounded algebra methods have been a valuable tool in algebraic topology and algebraic K-theory

Hidden Symmetries In String Theory, Iurii Chervonyi

Legacy Theses & Dissertations (2009 - 2024)

In this thesis we study hidden symmetries within the framework of string theory. Symmetries play a very important role in physics: they lead to drastic simplifications, which allow one to compute various physical quantities without relying on perturbative techniques.

A Three-Body Simulation Of Kepler-91 : A Potential Trojan System, Bryan Daniel D'Angelo

Legacy Theses & Dissertations (2009 - 2024)

This paper presents a three-body simulation of Kepler-91 (KIC 8219268) using parameters

Study Of Biologically Important Macromolecules By Nuclear Magnetic Resonance, Christopher Michael Demott

Legacy Theses & Dissertations (2009 - 2024)

Intrinsically disordered proteins or unstructured segments within proteins play an important role in cellular physiology and pathology. A combination of peptide aptamers selected by using the yeast-two-hybrid scheme, and in-cell NMR identified high affinity binders to a transiently structured intrinsically disordered proteins (IDP). This method was validated using the prokaryotic ubiquitin-like protein, Pup, of the Mycobacterium proteasome. We discover two peptide aptamers that bind to opposite sites of a transient helix in Pup, an intrinsically disordered protein, that have vastly different effects on the survival of Mycobacterium bovis BCG.

Site-Specific Functionalization Of Corannulene : Tailoring Structures And Properties, Cristina Dubceac

Legacy Theses & Dissertations (2009 - 2024)

Bowl-shaped polycyclic aromatic hydrocarbons (also referred to as buckybowls or π-bowls) are curved polyarenes that are structurally related to fullerenes. Corannulene, the smallest buckybowl which maps onto a one-third of the surface of C60, provides a great platform for functionalization. Various synthetic methods have been developed over the years to give access to a wealth of corannulene derivatives with many different properties and practical applications. In this work, we report on the controlled functionalization of the corannulene interior, while also employing the addition of different functionalities to its periphery for fine-tuning of the packing and bowl properties.

Evaluation Of Lightning Jumps As A Predictor Of Severe Weather In The Northeastern United States, Pamela Eck

Legacy Theses & Dissertations (2009 - 2024)

Severe weather events in the northeastern United States can be challenging to forecast, given how the evolution of deep convection can be influenced by complex terrain and the lack of quality observations in complex terrain. To supplement existing observations, this study explores using lightning to forecast severe convection in areas of complex terrain in the northeastern United States. A sudden increase in lightning flash rate by two standard deviations (2σ), also known as a lightning jump, may be indicative of a strengthening updraft and an increased probability of severe weather.

Structured Pseudospectra Of Block Matrix Structures, Richard Eric Ferro

Legacy Theses & Dissertations (2009 - 2024)

The study of pseudospectra Λε(A) dates back to the 1980s when it became an important analytical and graphical alternative for investigating non-normal matrices and operators. The interest in pseudospectra was further stimulated in the 1990s by the increasing avail- ability of numerical software such as Matlab, Eigtool and Seigtool. The main reason for the importance of pseudospectra is that eigenvalue analysis of non-self-adjoint operators can be misleading, which is most easily seen by looking at the 2-norm pseudospectra of non- normal matrices whose eigenvectors are not orthogonal. Many of the advances in the field are due to interactions between pure …