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Reducing Bacterial Resistance Through Better Antibiotic Prescription Practices, Christine Ouma
Reducing Bacterial Resistance Through Better Antibiotic Prescription Practices, Christine Ouma
Theses and Dissertations
The objective of this study was to find a regression procedure that can better explain the relationship between patterns of antibiotic use and proportions of bacterial resistance. The sample for the study is comprised of 44 University Health System Consortium (UHC) member hospitals, and the data for antibiotic use and proportions of resistance are from the years 2002 to 2005. The hospitals are spread across the Northeast, South, Southwest, Midwest, and Northwest regions of the USA. Based on statistical analysis, MRSA continues to have the highest proportion of resistance among the bacteria examined and has increased significantly since 2002. The …
A Stratigraphic And Depositional Interpretation Of A Sand Quarry In Middle Georgia, Jessica Taylor
A Stratigraphic And Depositional Interpretation Of A Sand Quarry In Middle Georgia, Jessica Taylor
Theses and Dissertations
Analysis of sediments from two sand quarries in Mauk, Georgia indicate braided stream environment. Sediment samples of both Pleistocene and Cretaceous age were collected, sedimentary features such as trough cross-bedding along with laminar bedding were recorded, and photos were taken to document the scale and stratigraphic sequences of the sediments. Petrified wood was collected throughout the two sand quarries indicating a terrestrial origin. Post-depositional modifications seen at some of sites include load and flame structures. Sediment samples were examined for grain-size distributions and other sediment textures.
Networks And Network Security, Michael Kuralt
Networks And Network Security, Michael Kuralt
Theses and Dissertations
The purpose of this thesis is to increase awareness of network security in the office and at home by educating the public, reinforcing business decisions, and providing guidelines for network security.
An Scir Model Of Meningococcal Meningitis, Kalimah Vereen
An Scir Model Of Meningococcal Meningitis, Kalimah Vereen
Theses and Dissertations
A model for meningitis is developed by adding a class of carriers to the basic SIR model. This model is used to analyze the impact a vaccination program can have on the health of the population of epidemic prone countries. Analysis of the model shows the local stability of the disease free equilibrium, the existence of an endemic equilibrium and computation of the reproduction number, ℜ0 . Using a MATLAB program we simulate a time course of the model using parameters gathered from the World Health Organization. The numerical solution demonstrates that our reproduction number was correct. We thenconcluded that …
Probe Level Analysis Of Affymetrix Microarray Data, Richard Ellis Kennedy
Probe Level Analysis Of Affymetrix Microarray Data, Richard Ellis Kennedy
Theses and Dissertations
The analysis of Affymetrix GeneChip® data is a complex, multistep process. Most often, methodscondense the multiple probe level intensities into single probeset level measures (such as RobustMulti-chip Average (RMA), dChip and Microarray Suite version 5.0 (MAS5)), which are thenfollowed by application of statistical tests to determine which genes are differentially expressed. An alternative approach is a probe-level analysis, which tests for differential expression directly using the probe-level data. Probe-level models offer the potential advantage of more accurately capturing sources of variation in microarray experiments. However, this has not been thoroughly investigated, since current research efforts have largely focused on the …
Characterization Of Microorganisms Of Interest To Homeland Security And Public Health Utilizing Liquid Chromatography/Mass Spectrometry, Robert A. Everley
Characterization Of Microorganisms Of Interest To Homeland Security And Public Health Utilizing Liquid Chromatography/Mass Spectrometry, Robert A. Everley
Theses and Dissertations
Liquid chromatography/quadrupole time of flight mass spectrometry (LC/QTOF MS) utilizing electrospray ionization was employed to monitor protein expression in Escherichia coli and Shigella organisms. Automated charge state deconvolution, spectral subtraction and spectral mirroring were used to reveal subtle differences in the LC/MS data. Reproducible intact protein biomarkers were discovered based on their unique mass, retention time and relative intensity. These markers were implemented to differentiate closely related strain types, (e.g. two distinct isolates of E. coli O157:H7) and to correctly identify unknown pathogens. Notable, was the distinction of multiple serotypes of enterohaemorrhagic E. coli which cannot be distinguished by clinical …
Properties And Recent Applications In Spectral Graph Theory, Michelle L. Rittenhouse
Properties And Recent Applications In Spectral Graph Theory, Michelle L. Rittenhouse
Theses and Dissertations
There are numerous applications of mathematics, specifically spectral graph theory, within the sciences and many other fields. This paper is an exploration of recent applications of spectral graph theory, including the fields of chemistry, biology, and graph coloring. Topics such as the isomers of alkanes, the importance of eigenvalues in protein structures, and the aid that the spectra of a graph provides when coloring a graph are covered, as well as others.The key definitions and properties of graph theory are introduced. Important aspects of graphs, such as the walks and the adjacency matrix are explored. In addition, bipartite graphs are …