Digital Commons Network^™

Effect Of Primary Care Physician Density On Late Stage Cervical Cancer Diagnosis, Emily Haanschoten

Theses and Dissertations

INTRODUCTION: Late-stage cervical cancer diagnosis is an important contributing factor to the cervical cancer mortality rate. Screening for cervical cancer is a vital tool in reducing the number of late-stage cases, preventing incident cases and reducing mortality. Access to care is often a significant barrier to receiving these services. Women who have no usual source of care report significantly lower percentages of Pap tests than women who have a usual source. South Carolina ranks 13th in the US in cervical cancer incidence and 7th in cervical cancer mortality. South Carolina also struggles with a primary care physician shortage, ranking 39th …

Health Professionals’ Roles In Animal Agriculture, Climate Change, And Human Health, Aysha Z. Akhtar, Michael Greger, Hope Ferdowsian, Erica Frank

Michael Greger, MD, FACLM

What we eat is rapidly becoming an issue of global concern. With food shortages, the rise in chronic disease, and global warming, the impact of our dietary choices seems more relevant today than ever. Globally, a transition is taking place toward greater consumption of foods of animal origin, in lieu of plantbased diets. With this transition comes intensification of animal agriculture that in turn is associated with the emergence of zoonotic infectious diseases, environmental degradation, and the epidemics of chronic disease and obesity. Health professionals should be aware of these trends and consider them as they promote healthier and more …

A Review Of Software For Analyzing Molecular Sequences, Haema Nilakanta, Kimberly L. Drews, Suzanne Firrell, Mary A. Foulkes, Kathleen A. Jablonski

GW Biostatistics Center

Background Over the past ten years, there has been an explosion of microbiome research. Many software packages for analyzing microbial sequences such as the 16S gene from 454 sequencers and Illumina platforms are available. But for a new researcher, it is difficult to know which package to choose. We present a systematic review of packages for the analysis of molecular sequences used to describe and compare microbial communities. This review gives students and researchers information to help choose the best analytic pipeline for their project. To the best of our knowledge, this is the first review of such software.

Findings …

Statistical Analysis And Modeling Of Pm2.5 Speciation Metals And Their Mixtures, Boubakari Ibrahimou

USF Tampa Graduate Theses and Dissertations

Exposure to fine particulate matter (PM_2.5) in the ambient air is associated with various health effects. There is increasing evidence which implicates the central role played by specific chemical components such as heavy metals of PM_2.5. Given the fact that humans are exposed to complex mixtures of environmental pollutants such as PM_2.5, research efforts are intensifying to study the mixtures composition and the emission sources of ambient PM, and the exposure-related health effects. Factor analysis as well source apportionment models are statistical tools potentially useful for characterizing mixtures in PM_2.5. However, classic …

Pharyngeal And Cervical Cancer Incidences Significantly Correlate With Personal Uv Doses Among Whites In The United States, Dianne E. Godar, Rong Tang, Stephen Merrill

Mathematics, Statistics and Computer Science Faculty Research and Publications

Because we found UV-exposed oral tissue cells have reduced DNA repair and apoptotic cell death compared with skin tissue cells, we asked if a correlation existed between personal UV dose and the incidences of oral and pharyngeal cancer in the United States. We analyzed the International Agency for Research on Cancer's incidence data for oral and pharyngeal cancers by race (white and black) and sex using each state's average annual personal UV dose. We refer to our data as ‘white’ rather than ‘Caucasian,’ which is a specific subgroup of whites, and ‘black’ rather than African-American because blacks from other countries …

Low Risk Of Attrition Among Adults On Antiretroviral Therapy In The Rwandan National Program: A Retrospective Cohort Analysis Of 6, 12, And 18 Month Outcomes, Harriet Nuwagaba-Biribonwoha, Aleksandra Jakubowski, Veronicah Mudisha, Paulin Basinga, Anita Asiimwe, Denis Nash, Batya Elul

Publications and Research

Background
We report levels and determinants of attrition in Rwanda, one of the few African countries with universal ART access.

Methods
We analyzed data abstracted from health facility records of a nationally representative sample of adults [≥18 years] who initiated ART 6, 12, and 18 months prior to data collection; and collected facility characteristics with a health facility assessment questionnaire. Weighted proportions and rates of attrition [loss to follow-up or death] were calculated, and patient- and health facility-level factors associated with attrition examined using Cox proportional hazard models.

Results
1678 adults initiated ART 6, 12 and 18 months prior to …

Analysis Of High Fat Diet Induced Genes During Mammary Gland Development: Identifying Role Players In Poor Prognosis Of Breast Cancer, Raquel C. Martinez-Chacin, Megan Keniry, Robert Dearth

Biology Faculty Publications and Presentations

Background

Epidemiological studies have shown that consumption of a high-fat diet (HFD) increases the risk of developing breast cancer (BC). Studies in rodents have shown HFD causes changes in the genetic programming of the maturing mammary gland (MG) increasing the susceptibility of developing the disease. Less is known about how HFD induced genes impact BC development. HFD exposure two weeks before conception to six weeks of age was previously shown to dramatically change MG gene expression in 10 week old mice. Therefore, we investigated these differentially expressed HFD-induced genes for their expression in BC using the NKI 295 breast tumor …

Examining The Influence Of Farmers' Market Motivations On Access To Healthful Foods And Business Opportunities For Farms, Rachel K. Ward

Electronic Theses and Dissertations

Farmers’ markets are increasingly promoted as mechanisms for improving access to healthful foods for low-income households, as they are relatively inexpensive to establish and they can provide affordable food for low-income households by offering Supplemental Nutrition Assistance Program Electronic Benefit Transfer (SNAP/EBT). SNAP/EBT at markets also expands revenue opportunities for participating farmers. Market mangers provide a critical role in overseeing SNAP/EBT at markets and influencing business opportunities for farmers. Using a mixed-method approach, this study aimed to evaluate how managers’ motivations influence SNAP/EBT availability and participation at markets and business opportunities for small- and moderate- sized farms.

To develop a …

Examining The Influence Of Farmers' Market Managers’ Perceived Roles On Access To Healthful Foods For Low-Income Households And Business Opportunities For Small- And Moderate-Size Farms, Rachel K. Ward

Rachel K Ward

Farmers’ markets are increasingly promoted as mechanisms for improving access to healthful foods for low-income households, as they are relatively inexpensive to establish and they can provide affordable food for low-income households by offering Supplemental Nutrition Assistance Program Electronic Benefit Transfer (SNAP/EBT). SNAP/EBT at markets also expands revenue opportunities for participating farmers. Market mangers provide a critical role in overseeing SNAP/EBT at markets and influencing business opportunities for farmers. Using a mixed-method approach, this study aimed to evaluate how managers’ motivations influence SNAP/EBT availability and participation at markets, and business opportunities for small- and moderate- sized farms. To develop a …

Full Issue, Volume 2, Number 2, Donna J. Peterson

Journal of Human Sciences and Extension

No abstract provided.

Vegetarian Dietary Patterns: Mortality, Colorectal Cancer, And Food Consumption, Michael John Orlich

Loma Linda University Electronic Theses, Dissertations & Projects

Objective Vegetarian dietary patterns represent longstanding, real-world diets consumed by a minority of persons. Studies of important health outcomes of such diets, particularly for all-cause mortality and colorectal cancer risk, have yielded inconsistent results. We sought to examine these outcomes (mortality and colorectal cancer incidence) in a large North-American cohort. We also sought to further characterize potentially important differences in the food consumption patterns of these diets. Design Baseline diet was measured by a quantitative food frequency questionnaire among more than 96,000 Seventh-day Adventists in the US and Canada, enrolled from 2002-2007. Dietary patterns were defined, based on the reported …

How To Approach Research : A Guide For Child Life Specialists, Emily L. Springer

Graduate Student Independent Studies

This how-to guide aims to increase the understanding of research and provide child life specialists and students a concise and easy tool to access information about how they incorporate research into their work.

Ultraviolet Radiation, Aging And The Skin: Prevention Of Damage By Topical Camp Manipulation, Alexandra Amaro-Ortiz, Betty Yan, John A. D’Orazio

Markey Cancer Center Faculty Publications

Being the largest and most visible organ of the body and heavily influenced by environmental factors, skin is ideal to study the long-term effects of aging. Throughout our lifetime, we accumulate damage generated by UV radiation. UV causes inflammation, immune changes, physical changes, impaired wound healing and DNA damage that promotes cellular senescence and carcinogenesis. Melanoma is the deadliest form of skin cancer and among the malignancies of highest increasing incidence over the last several decades. Melanoma incidence is directly related to age, with highest rates in individuals over the age of 55 years, making it a clear age-related disease. …

Nutritional Counseling At Jeffhope, Cara Siegel, Msii, Anita Modi, Msiii, Amy Tressan, Msi

CwiC-PH

INTRODUCTION

Obesity is a major national public health concern and is strongly associated with increased morbidity and mortality.¹ Specifically, obesity is correlated to increased frequency in coronary artery disease², type two diabetes³, some cancers⁴, and other serious health conditions⁵. An epidemiological study of 21 developed countries found that increased waist size, weight, and BMI were all associated with low income.⁷ Importantly, obesity has a high prevalence among the homeless population, one study finding 42.8% of homeless women obese.¹⁷ It has been reported that 39% of sheltered homeless Americans are …

Quality Of Primary Care From The Patient Perspective In Saudi Arabia : A Multi-Level Study., Khalid Awad Alahmary

Electronic Theses and Dissertations

Objectives: To assess primary care performance for measures of patients’ experience in Community-based Primary Care (CPC) and Employer-based Primary Care (EPC) systems in Saudi Arabia, to examine variations in performance across the two systems, and to explore factors at both the individual-level and the organizational-level that explain variations in primary care performance. Design and Methods: This is an observational and cross-sectional study, using comparative design and survey research methods. The newly revised and re-translated Arabic version of the Primary Care Assessment Survey (PCAS) was used to measure patients’ experience of primary care. PCAS operationalizes the IOM definition of primary care, …

Spatiotemporal Distribution Of Genus Culex (Diptera: Culicidae) In Usf Ecopreserve, Hillsborough County, Florida, Emily Schwartz

USF Tampa Graduate Theses and Dissertations

Within the state of Florida, there are three arboviruses of public health importance that can cause neuroinvasive disease in humans: West Nile Virus, Saint Louis Encephalitis Virus, and Eastern Equine Encephalitis Virus. Mosquitoes (Diptera: Culicidae) within the genus Culex are known and suspected vectors of these diseases. The vectors of these diseases can be present in urban wetland habitats that allow for exposure to residential communities. Vector ecology must be investigated in order to understand the dynamics of disease transmission. In Hillsborough County, Florida the spatial and temporal distribution of these vectors are not well established. An ecological study was …

Workplace Social Capital And Mental Health Among Chinese Employees: A Multi-Level, Cross-Sectional Study, Junling Gao, Scott Weaver, Jumming Dai, Yingnan Jia, Xingdi Liu, Kezhi Jin, Hua Fu

Public Health Faculty Publications

Background: Whereas the majority of previous research on social capital and health has been on residential neighborhoods and communities, the evidence remains sparse on workplace social capital. To address this gap in the literature, we examined the association between workplace social capital and health status among Chinese employees in a large, multilevel, cross-sectional study. Methods: By employing a two-stage stratified random sampling procedure, 2,796 employees were identified from 35 workplaces in Shanghai during March to November 2012. Workplace social capital was assessed using a validated and psychometrically tested eight-item measure, and the Chinese language version of the WHO-Five Well-Being Index …

Global Rise In Human Infectious Disease Outbreaks, Katherine F. Smith, Michael Goldberg, Samantha R. Rosenthal, Lynn Carlson, Jane Chen, Cici Chen, Sohini Ramachandran

Health & Wellness Department Faculty Publications and Research

No abstract provided.

Sex-Specific Triacylglycerides Are Widely Conserved In Drosophila And Mediate Mating Behavior, Jacqueline S.R Chin, Shane R. Ellis, Huong T. Pham, Stephen J. Blanksby, Kenji Mori, Qi Ling Koh, William J. Etges, Joanne Y. Yew

Faculty of Science, Medicine and Health - Papers: part A

Pheromones play an important role in the behavior, ecology, and evolution of many organisms. The structure of many insect pheromones typically consists of a hydrocarbon backbone, occasionally modified with various functional oxygen groups. Here we show that sex-specific triacylclyerides (TAGs) are broadly conserved across the subgenus Drosophila in 11 species and represent a novel class of pheromones that has been largely overlooked. In desert-adapted drosophilids, 13 different TAGs are secreted exclusively by males from the ejaculatory bulb, transferred to females during mating, and function synergistically to inhibit courtship from other males. Sex-specific TAGs are comprised of at least one short …

The Burden Of Avian Influenza Viruses In Community Ponds In California, Zin Htway

Walden Dissertations and Doctoral Studies

Emerging influenza viruses continue to challenge public health. The problem is public health science professionals have been battling emerging human influenza diseases with tactile and reactionary methods because there is a lack of knowledge and data at the human-animal interface. This research was a baseline study of the proportion of influenza A virus (IAV) in urban and rural communities in California. The population was artificial recirculating water ponds in the geographic locations of rural and urban Californian communities. Surface water samples [N = 182] were collected from artificial recirculating ponds in California. Positivity for IAV was verified by real time …

Distribution Of Wildlife Rabies In Central Appalachia And Analysis Of Factors Influencing Human Exposure, Sara J. Reilly

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Abstract Background: The rabies virus is a Lyssavirus of the family Rhabdoviridae which affects all mammals and causes progressive encephalomyelitis that is fatal in nearly one hundred percent of untreated cases. In the United States, wildlife act as the primary reservoir for rabies and prevention, surveillance, and control costs remain high. The purpose of this study is to understand the current distribution of wildlife rabies in Central Appalachia, as well as identify any demographic or geographic factors which may affect the risk of human exposure at the county level. Methods: A spatial statistical analysis using StatScan was performed to identify …

Interaction Between Climatic, Environmental, And Demographic Factors On Cholera Outbreaks In Kenya, James D. Stoltzfus, Jane Y. Carter, Muge Akpinar-Elci, Martin Matu, Victoria Kimotho, Mark J. Giganti, Daniel Langat, Omur C. Elsi

Community & Environmental Health Faculty Publications

Background:

Cholera remains an important public health concern in developing countries including Kenya where 11,769 cases and 274 deaths were reported in 2009 according to the World Health Organization (WHO). This ecological study investigates the impact of various climatic, environmental, and demographic variables on the spatial distribution of cholera cases in Kenya.

Methods:

District-level data was gathered from Kenya’s Division of Disease Surveillance and Response, the Meteorological Department, and the National Bureau of Statistics. The data included the entire population of Kenya from 1999 to 2009.

Results:

Multivariate analyses showed that districts had an increased risk of cholera outbreaks when …

Testing The Ability Of Topoclimatic Grids Of Extreme Temperatures To Explain The Distribution Of The Endangered Brush-Tailed Rock-Wallaby (Petrogale Penicillata), Michael B. Ashcroft, Mike Cavanagh, Mark D. Eldridge, John R. Gollan

Faculty of Science, Medicine and Health - Papers: part A

Aim Many species are susceptible to climatic extremes, yet few fine-scale studies consider the factors that determine the distribution of extreme temperatures at landscape and regional scales. These factors include cold air drainage, canopy cover and topographical exposure to winds and radiation. We used the brush-tailed rock-wallaby (Petrogale penicillata) to test whether innovative topoclimatic grids of extreme temperatures are an important predictor of regional-scale species distributions. Location Hunter Valley region, New South Wales, Australia (31.2-33.4° S, 148.6-153.0° E). Methods We modelled the regional distributions of rock-wallaby observations and colonies using topoclimatic, macroclimatic, topographical and habitat factors. We employed a randomization …

A Simulation Study To Quantify Drift Fence Configuration And Spacing Effects When Sampling Mobile Animals, Murray Ellis, Michael Bedward

Faculty of Science, Medicine and Health - Papers: part A

Drift fences with traps are commonly used for ecological research and survey. Field studies have examined the effectiveness of selected fence layouts, but comprehensive field testing is impractical. We applied a simulation approach to investigate how the interaction of fence layout and animal movement type influence fence encounter rates. A range of fence layouts, varying in spacing and configuration, were chosen based on common field practices and recommendations in the literature. Animal movement patterns ranged from meandering (Brownian) to highly directional over distances of 10 to 500 m. We found that fences in short, straight, widely spaced arrangements would be …

Exposure To Endocrine Disrupting Chemicals And Male Reproductive Health, Hueiwang Anna Jeng

Community & Environmental Health Faculty Publications

Endocrine disrupting chemicals (EDCs) can interfere with normal hormonal balance and may exert adverse consequences on humans. The male reproductive system may be susceptible to the effects of such environmental toxicants. This review discusses the recent progress in scientific data mainly from epidemiology studies on the associations between EDCs and male reproductive health and our understanding of possible mechanisms associated with the effects of EDCs on male reproductive health. Finally, the review provides recommendations on future research to enhance our understanding of EDCs and male reproductive health. The review highlights the need for (1) well-defined longitudinal epidemiology studies, with appropriately …

The Ecological Fallacy Of The Role Of Age In Chronic Disease And Hospital Demand, David Whyatt, Raji Tenneti, Julie Marsh, Anna Kemp, Laura Firth, Kevin Murray, Berwin Turlach, Alistair Vickery

Illawarra Health and Medical Research Institute

Objective: To examine the relationship between age and all-cause hospital utilization in the years preceding and following a diagnosis in hospital of heart failure, type 2 diabetes, or chronic obstructive pulmonary disease (COPD). Research Design: A cohort study of all patients in Western Australia who have had a principal diagnosis of heart failure, type 2 diabetes, or COPD, upon admission to hospital. All-cause hospital utilization 6 years preceding and 4 years following cardinal events, that is, a disease-specific diagnosis upon hospital admission, where such an event has not occurred in the previous 2 years, are examined in specific age groups. …

Comparative Study Of Helminth Parasites Of The Many-Ribbed Salamander, Eurycea Multiplicata And Oklahoma Salamander, Eurycea Tynerensis (Caudata: Plethodontidae), From Arkansas And Oklahoma, A, C. T. Mcallister, M. B. Connior, C. R. Bursey, H. W. Robison

Journal of the Arkansas Academy of Science

Ninety many-ribbed salamanders, Eurycea multiplicata and 135 Oklahoma salamanders, Eurycea tynerensis were collected between April 2010 and April 2014 from 14 counties of Arkansas and McCurtain County, Oklahoma (E. multiplicata only) and examined for helminth parasites. Twelve (13%) E. multiplicata were infected, including two (2%) each with Brachycoelium salamandrae, Bothriocephalus rarus, Batracholandros magnavulvaris, Cosmocercoides variabilis, and Omeia papillocauda, and one (1%) each with an oligacanthorhynchid cystacanth and Fessisentis vancleavei. Forty-one (30%) of the E. tynerensis were infected, including seven (5%) with Gorgoderina tenua, two (1%) each with Phyllodistomum solidum and cyclophyllidean tapeworm cysticerci, one (0.7%) with Cylindrotaenia americana, six (3%) …

Atrazine In Maternal Drinking Water Supply Below The Federal Maximum Contaminant Level And Risk Of Preterm Birth, Small For Gestational Age, Cryptorchidism And Hypospadias, Daniel Rice

Legacy Theses & Dissertations (2009 - 2024)

The prevalence of preterm birth, small for gestational age (SGA), and hypospadias has been increasing for several decades in the U.S resulting in significant morbidity and mortality and direct costs to society. Drinking water provides a mechanism for prolonged chronic exposure to environmental contaminants but is one of the least assessed environmental exposures in pregnancy and birth outcomes. To test the hypothesis that maternal exposure to atrazine through drinking water during pregnancy, or one or more trimesters of gestation, is associated with an increased risk of preterm birth, small for gestational age, cryptorchidism and hypospadias a retrospective cohort study was …

Antibiotic Usage In Relation To Resistant Bacterial Infections And Liver And Kidney Cancer Outcomes In South Carolina, Prea Thathiah

Theses and Dissertations

Antibiotics are one of the most beneficial discoveries in medicine and public health. However, the use, overuse, and misuse of these drugs have led to increases in antibiotic resistant bacterial infections (ARI). Furthermore, previous epidemiological studies have linked antibiotic use to breast cancer, but these studies have not included effects on metabolic organs, such as the liver and kidneys. This dissertation investigates the role of antibiotic use in infections and liver and kidney cancers in the state of South Carolina. Using ecological study methods and Poisson regression to determine relative risk ratios, it was found that antibiotic use is a …

Exposure To Multiple Parasites Is Associated With The Prevalence Of Active Convulsive Epilepsy In Sub-Saharan Africa, Gathoni Kamuyu, Christian Bottomley, James Mageto, Brett Lowe, Patricia Wilkins, John C. Noh, Thomas B. Nutman, Anthony Ngugi, Rachael Odhiambo, Ryan Wagner, Angelina Kakooza-Mwesige, Seth Owusu-Agyei, Kenneth Ae-Ngibise, Honorati Masanja, Faith Osier, Peter Odermatt, Charles Newton

Family Medicine, East Africa

Background: Epilepsy is common in developing countries, and it is often associated with parasitic infections. We investigated the relationship between exposure to parasitic infections, particularly multiple infections and active convulsive epilepsy (ACE), in five sites across sub-Saharan Africa.

Methods and Findings: A case-control design that matched on age and location was used. Blood samples were collected from 986 prevalent cases and 1,313 age-matched community controls and tested for presence of antibodies to Onchocerca volvulus, Toxocara canis, Toxoplasma gondii, Plasmodium falciparum, Taenia solium and HIV. Exposure (seropositivity) to Onchocerca volvulus (OR = 1.98; 95%CI: 1.52-2.58, p

Conclusion: This study investigates how …