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The Interpretive Approach As A Means Of Understanding The Misunderstood, Doreen Molloy, Joyce Hendricks, Anne Williams Nov 2016

The Interpretive Approach As A Means Of Understanding The Misunderstood, Doreen Molloy, Joyce Hendricks, Anne Williams

Research outputs 2014 to 2021

People’s experiences of health and illness are important areas of health research and practice. The interpretive process, and more significantly the biographical approach (Denzin, 1989), is an approach in which there is a focus on personal epiphanies which shape and reflect the stories people tell of their experiences. Dolby-Stahl (1985) contends stories of personal experience sit within the genre of folklore and that the reading of such stories must take into account the social, cultural, and historical contexts which influence and give meaning to experience.


The Efficacy Of A Group Cognitive Behavioral Therapy For War-Affected Young Migrants Living In Australia: A Cluster Randomized Controlled Trial, Chew S. Ooi, Rosanna M. Rooney, Clare Roberts, Robert T. Kane, Bernadette Wright, Nikos Chatzisarantis Oct 2016

The Efficacy Of A Group Cognitive Behavioral Therapy For War-Affected Young Migrants Living In Australia: A Cluster Randomized Controlled Trial, Chew S. Ooi, Rosanna M. Rooney, Clare Roberts, Robert T. Kane, Bernadette Wright, Nikos Chatzisarantis

Research outputs 2014 to 2021

Background: Preventative and treatment programs for people at risk of developing psychological problems after exposure to war trauma have mushroomed in the last decade. However, there is still much contention about evidence-based and culturally sensitive interventions for children. The aim of this study was to examine the efficacy of the Teaching Recovery Techniques in improving the emotional and behavioral outcomes of war-affected children resettled in Australia.

Methods and Findings: A cluster randomized controlled trial with pre-test, post-test, and 3-month follow-up design was employed. A total of 82 participants (aged 10–17 years) were randomized by school into the 8-week intervention ( …


Photoaging Photography: Mothers' Attitudes Toward Adopting Skin-Protective Measures Pre- And Post-Viewing Photoaged Images Of Their And Their Child's Facial Sun Damage, Matthew Welch, Paul Chang, Myra F. Taylor Oct 2016

Photoaging Photography: Mothers' Attitudes Toward Adopting Skin-Protective Measures Pre- And Post-Viewing Photoaged Images Of Their And Their Child's Facial Sun Damage, Matthew Welch, Paul Chang, Myra F. Taylor

Research outputs 2014 to 2021

One of the major sources for children to gain knowledge of skin-protective measures is from their parents. Therefore, an imperative exists for parents to model and reinforce the sun-safety practices they want their children to adopt. Although Australian mothers have been the recipients of two extensive sun-safety public health campaigns, little is known about their attitudes, behaviors, and application of health promotion knowledge toward their and their child’s ultraviolet (UV) sun exposure. Ten mothers with children aged 4 to 12 years were asked a series of questions about their sun-safety practices, both pre- and post-viewing an UV photoaged photograph of …


Real-Time Netnography: Rejecting The Passive Shift, Leesa Costello, Marie-Louise Mcdermott Apr 2016

Real-Time Netnography: Rejecting The Passive Shift, Leesa Costello, Marie-Louise Mcdermott

Research outputs 2014 to 2021

Although netnography emerged in the 1990s, it is a term unfamiliar to many ethnographers and is still touted as a new methodology. Once explained, ethnographers often understand it in terms of online ethnography. While this is helpful, netnography, however, offers a set of steps and analytic approaches that can be applied across a spectrum of involvement online. Its focus is on gaining entree to an online community, distinguishing between participant observation and nonparticipant observation.


Discriminant Validity Of The Hospital Anxiety And Depression Scale, Beck Depression Inventory (Ii) And Beck Anxiety Inventory To Confirmed Clinical Diagnosis Of Depression And Anxiety In Patients With Chronic Obstructive Pulmonary Disease, Tina Phan, Owen Carter, Claire Adams, Grant Waterer, Li Ping Chung, Maxine Hawkins, Cobie Rudd, Mel R. Ziman, Natalie Strobel Jan 2016

Discriminant Validity Of The Hospital Anxiety And Depression Scale, Beck Depression Inventory (Ii) And Beck Anxiety Inventory To Confirmed Clinical Diagnosis Of Depression And Anxiety In Patients With Chronic Obstructive Pulmonary Disease, Tina Phan, Owen Carter, Claire Adams, Grant Waterer, Li Ping Chung, Maxine Hawkins, Cobie Rudd, Mel R. Ziman, Natalie Strobel

Research outputs 2014 to 2021

The objective of this study was to investigate the discriminant validity of commonly used depresson and anxiety screening tools in order to determine the most suitable tool for patients with chronic obstructive pulmonary disease (COPD). COPD patients (n = 56) completed the Hospital Anxiety and Depression Scale (HADS), Beck Depression Inventory (BDI-II) and Beck Anxiety Inventory (BAI). These scores were compared to confirmed clinical diagnosis of depression and anxiety using the Mini Neuropsychiatric Interview. HADS depression subscale (HADS-D) sensitivity/specificity was 78/81 %; BDI-II 89/77 %; HADS anxiety subscale (HADS-A) 71/81 %; and BAI 89/62 %. HADS-D sensitivity/specificity was improved …


Fine Particulate Air Pollution And Hospital Emergency Room Visits For Respiratory Disease In Urban Areas In Beijing, China, In 2013, Qin Xu, Xia Li, Shuo Wang, Chao Wang, Fangfang Huang, Qi Gao, Lijuan Wu, Lixin Tao, Jin Guo, Wei Wang, Xiuhua Guo Jan 2016

Fine Particulate Air Pollution And Hospital Emergency Room Visits For Respiratory Disease In Urban Areas In Beijing, China, In 2013, Qin Xu, Xia Li, Shuo Wang, Chao Wang, Fangfang Huang, Qi Gao, Lijuan Wu, Lixin Tao, Jin Guo, Wei Wang, Xiuhua Guo

Research outputs 2014 to 2021

Background

Heavy fine particulate matter (PM2.5) air pollution occurs frequently in China. However, epidemiological research on the association between short-term exposure to PM2.5 pollution and respiratory disease morbidity is still limited. This study aimed to explore the association between PM2.5 pollution and hospital emergency room visits (ERV) for total and cause-specific respiratory diseases in urban areas in Beijing. Methods Daily counts of respiratory ERV from Jan 1 to Dec 31, 2013, were obtained from ten general hospitals located in urban areas in Beijing. Concurrently, data on PM2.5 were collected from the Beijing Environmental Protection Bureau, …


Predictors Of Sun Protection Behaviours And Sunburn Among Australian Adolescents, Simone Pettigrew, Michelle Jongenelis, Mark Strickland, Carolyn Minto, Terry Slevin, Geoffrey Jalleh, Chad Lin Jan 2016

Predictors Of Sun Protection Behaviours And Sunburn Among Australian Adolescents, Simone Pettigrew, Michelle Jongenelis, Mark Strickland, Carolyn Minto, Terry Slevin, Geoffrey Jalleh, Chad Lin

Research outputs 2014 to 2021

Background

Excessive sun exposure and sunburn increase individuals’ risk of skin cancer. It is especially important to prevent sunburn in childhood due to the higher relative risk of skin cancer across the life span compared to risk associated with sunburn episodes experienced later in life. This study examined demographic and attitudinal factors associated with engagement in a range of sun protection behaviours (wearing a hat, wearing protective clothing, staying in the shade, and staying indoors during the middle of the day) and the frequency of sunburn among Western Australian adolescents to provide insights of relevance for future sun protection campaigns. …


Plasma Apolipoprotein J As A Potential Biomarker For Alzheimer's Disease: Australian Imaging, Biomarkers And Lifestyle Study Of Aging, Veer Gupta, James D. Doecke, Eugene Hone, Steve Pedrini, Simon M. Laws, Madhav Thambisetty, Ashley Bush,, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Stuart Lance Macaulay, Alan Rembach, Stephanie R. Rainey-Smith, Ralph N. Martins Jan 2016

Plasma Apolipoprotein J As A Potential Biomarker For Alzheimer's Disease: Australian Imaging, Biomarkers And Lifestyle Study Of Aging, Veer Gupta, James D. Doecke, Eugene Hone, Steve Pedrini, Simon M. Laws, Madhav Thambisetty, Ashley Bush,, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Stuart Lance Macaulay, Alan Rembach, Stephanie R. Rainey-Smith, Ralph N. Martins

Research outputs 2014 to 2021

Introduction:

For early detection of Alzheimer's disease (AD), the field needs biomarkers that can be used to detect disease status with high sensitivity and specificity. Apolipoprotein J (ApoJ, also known as clusterin) has long been associated with AD pathogenesis through various pathways. The aim of this study was to investigate the potential of plasma apoJ as a blood biomarker for AD.

Methods:

Using the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging, the present study assayed plasma apoJ levels over baseline and 18 months in 833 individuals. Plasma ApoJ levels were analyzed with respect to clinical classification, age, gender, …


Humanising The Curriculum: The Role Of A Virtual World, Beverley Ewans, Sara Geale, Caroline Vafeas, Fiona Foxall, Barbara Loessl, Aisling Smyth, Christopher Mccafferty Jan 2016

Humanising The Curriculum: The Role Of A Virtual World, Beverley Ewans, Sara Geale, Caroline Vafeas, Fiona Foxall, Barbara Loessl, Aisling Smyth, Christopher Mccafferty

Research outputs 2014 to 2021

Objective:

Technology has changed our world; changed the way we communicate, the way we do business and the way education is delivered. As a result, undergraduate student cohorts come to university equipped with new technology, and educators need to transform the delivery of the curricula to satisfy a variety of learning styles. Nursing education, in particular, is developing and transforming to incorporate technology into the learning environment. Clinical placement opportunities are often sparse and alternative experiences need to be considered. Across nursing curricula, it has been recognised that technology has the capacity to provide real-life learning experiences that promote …


Nurse Staffing And Workload Drivers In Small Rural Hospitals: An Imperative For Evidence, Diane E. Twigg, Jennifer H. Cramer, Judith D. Pugh Jan 2016

Nurse Staffing And Workload Drivers In Small Rural Hospitals: An Imperative For Evidence, Diane E. Twigg, Jennifer H. Cramer, Judith D. Pugh

Research outputs 2014 to 2021

Purpose:

The aim of this study was to explore staffing issues and the workload drivers influencing nursing activities in designated small rural hospitals of Western Australia. A problem for small rural hospitals is an imbalance between nurse staffing resources and work activity.

Sample:

A purposive sample of 17 nurse leaders employed at designated small rural hospitals in Western Australia.

Method:

A qualitative research design was used. Data were collected by focus group and semi-structured interviews and review of Western Australian Country Health Service records. Thematic analysis was used to interpret data.

Findings:

A minimum nurse staffing model is in use. …


A Case-Control Study In An Orcadian Population Investigating The Rrelationship Between Human Plasma N-Glycans And Metabolic Syndrome, Fiona Mclachlan, Maria Timofeeva, Mairead Bermingham, Sarah Wild, Igor Rudan, Gordon Lauc, Wei Wang, Harry Campbell, James Wilson, Evropi Theodoratou Jan 2016

A Case-Control Study In An Orcadian Population Investigating The Rrelationship Between Human Plasma N-Glycans And Metabolic Syndrome, Fiona Mclachlan, Maria Timofeeva, Mairead Bermingham, Sarah Wild, Igor Rudan, Gordon Lauc, Wei Wang, Harry Campbell, James Wilson, Evropi Theodoratou

Research outputs 2014 to 2021

Background:

Alterations in glycosylation patterns have long been known to reflect changes in cell metabolism. In this study, we investigated the relationship between human N-glycan profiles and metabolic syndrome.

Method:

Between 2005 and 2011, 2,155 individuals from the Orkney Islands (UK) were recruited and biological material, alongside phenotypic measures were collected. Individual N-glycan profiles were measured in plasma using weak anion exchange high performance liquid chromatography and calibrated hydrophilic interaction liquid chromatography. Pre-specified criteria were used to identify 564 cases with metabolic syndrome and 1475 controls. We applied logistic regression to test for association between this binary outcome against measured …


Profiling Igg N-Glycans As Potential Biomarker Of Chronological And Biological Ages: A Community-Based Study In A Han Chinese Population, Xinwei Yu, Youix Wang, Jasminka Krištić, Jing Dong, Xi Chu, Siqi Ge, Hao Wang, Honghong Fang, Qing Gao, Di Lui, Zhongya Zhao, Hongli Peng, Maja P. Baković, Lijuan Wu, Manshu Song, Igor Rudan, Harry Campbell, Gordan Lauc, Wei Wang Jan 2016

Profiling Igg N-Glycans As Potential Biomarker Of Chronological And Biological Ages: A Community-Based Study In A Han Chinese Population, Xinwei Yu, Youix Wang, Jasminka Krištić, Jing Dong, Xi Chu, Siqi Ge, Hao Wang, Honghong Fang, Qing Gao, Di Lui, Zhongya Zhao, Hongli Peng, Maja P. Baković, Lijuan Wu, Manshu Song, Igor Rudan, Harry Campbell, Gordan Lauc, Wei Wang

Research outputs 2014 to 2021

As an important post-translation modifying process, glycosylation significantly affects the structure and function of immunoglobulin G (IgG) molecules and is essential in many steps of the inflammatory cascade. Studies have demonstrated the potential of using glycosylation features of IgG as a component of predictive biomarkers for chronological age in several European populations, whereas no study has been reported in Chinese. Herein, we report various patterns of changes in IgG glycosylation associated with age by analyzing IgG glycosylation in 701 community-based Han Chinese (244 males, 457 females; 23-68 years old). Eleven IgG glycans, including FA2B, A2G1, FA2[6]G1, FA2[3]G1, FA2[6]BG1, FA2[3]BG1, A2G2, …


The Association Between Glycosylation Of Immunoglobulin G And Hypertension: A Multiple Ethnic Cross-Sectional Study, Youxin Wang, Lucija Klarić, Xinwei Yu, Kujtim Thaqi, Jing Dong, Mislav Novokmet, Jim Wilson, Ozren Polasek, Youqin Liu, Jasminka Krištić, Siqi Ge, Maja Pučić-Baković, Lijuan Wu, Yong Zhou, Ivo Ugrina, Manshu Song, Jie Zhang, Xiuhua Guo, Qiang Zeng, Igor Rudan, Harry Campbell, Yurii Aulchenko, Gordan Lauc, Wei Wang Jan 2016

The Association Between Glycosylation Of Immunoglobulin G And Hypertension: A Multiple Ethnic Cross-Sectional Study, Youxin Wang, Lucija Klarić, Xinwei Yu, Kujtim Thaqi, Jing Dong, Mislav Novokmet, Jim Wilson, Ozren Polasek, Youqin Liu, Jasminka Krištić, Siqi Ge, Maja Pučić-Baković, Lijuan Wu, Yong Zhou, Ivo Ugrina, Manshu Song, Jie Zhang, Xiuhua Guo, Qiang Zeng, Igor Rudan, Harry Campbell, Yurii Aulchenko, Gordan Lauc, Wei Wang

Research outputs 2014 to 2021

More than half of all known proteins, and almost all membrane and extra-cellular proteins have oligosaccharide structures or glycans attached to them. Defects in glycosylation pathways are directly involved in at least 30 severe human diseases. A multiple center cross-sectional study (China, Croatia, and Scotland) was carried out to investigate the possible association between hypertension and IgG glycosylation. A hydrophilic interaction chromatography of fluorescently labeled glycans was used to analyze N-glycans attached to IgG in plasma samples from a total of 4757 individuals of Chinese Han, Croatian, and Scottish ethnicity. Five glycans (IgG with digalactosylated glycans) significantly differed in participants …


Exploratory Psychomteric Properties Of The Farsi And English Version Of Spiritual Needs Questionnaire (Spnq), Nejat Nazi, Lisa Whitehead, Marie Crowe Jan 2016

Exploratory Psychomteric Properties Of The Farsi And English Version Of Spiritual Needs Questionnaire (Spnq), Nejat Nazi, Lisa Whitehead, Marie Crowe

Research outputs 2014 to 2021

The aim of this study was to translate and test the psychometric properties of a Farsi and an English version of the spiritual needs questionnaire (SpNQ) a measure originally developed in German. The World Health Organization guideline for translating and validating questionnaires was used. Participants were recruited from hospitals in Iran and New Zealand during an outpatient follow-up appointment after cancer treatment. People diagnosed with cancer in Iran (68) and New Zealand (54) completed and returned the SpNQ (at time 1) and within the two week time period (time 2). Cronbach’s alpha ranged from 0.79 to 0.92, except for the …


Investigation Of The Relationship Between Chronic Stress And Insulin Resistance In A Chinese Population, Yuxiang Yan, Huanbo Xiao, Sisi Wang, Jing Zhao, Yan He, Wei Wang, Jing Dong Jan 2016

Investigation Of The Relationship Between Chronic Stress And Insulin Resistance In A Chinese Population, Yuxiang Yan, Huanbo Xiao, Sisi Wang, Jing Zhao, Yan He, Wei Wang, Jing Dong

Research outputs 2014 to 2021

Background:

Chronic stress may facilitate the development of metabolic diseases. Insulin resistance is present long before the clinical manifestations of individual metabolic abnormalities. To explore whether chronic stress is an independent risk factor of insulin resistance, we investigated the relationship between the stress system, selected parameters of energy homeostasis, and insulin resistance in a Chinese population.

Methods:

We recruited 766 workers employed at four companies in Beijing. The degree of insulin resistance was determined using the homeostasis model assessment of insulin resistance (HOMA-IR). The highest quartile of HOMA-IR among all study subjects was further defined as insulin resistance in our …


Using Technology, Bioinformatics And Health Informatics Approaches To Improve Learning Experiences In Optometry Education, Research And Practice, Vivek K. Gupta, Veer B. Gupta Jan 2016

Using Technology, Bioinformatics And Health Informatics Approaches To Improve Learning Experiences In Optometry Education, Research And Practice, Vivek K. Gupta, Veer B. Gupta

Research outputs 2014 to 2021

Rapid advances in ocular diagnostic approaches and emerging links of pathological changes in the eye with systemic disorders have widened the scope of optometry as the front line of eye health care. Expanding professional requirements stipulate that optometry students get a meticulous training in relevant information and communication technologies (ICT) and various bioinformatics and health informatics software to meet current and future challenges. Greater incorporation of ICT approaches in optometry education can facilitate increased student engagement in shared learning experiences and improve collaborative learning. This, in turn, will enable students to participate in and prepare for the complex real-world situations. …


Socioeconomic, Bio-Demographic And Health/Behavioral Determinants Of Neonatal Mortality In Nigeria: A Multilevel Analysis Of 2013 Demographic And Health Survey, Emmanuel O. Adewuyi, Yun Zhao, Reeta Lamichhane Jan 2016

Socioeconomic, Bio-Demographic And Health/Behavioral Determinants Of Neonatal Mortality In Nigeria: A Multilevel Analysis Of 2013 Demographic And Health Survey, Emmanuel O. Adewuyi, Yun Zhao, Reeta Lamichhane

Research outputs 2014 to 2021

Background:

Nigeria ranks as one of the countries in the world with considerable burden of neonatal mortality. This study aims to investigate the association of socioeconomic, bio-demographic and health/behavioural factors with neonatal mortality in the country using the most current available evidence.

Methods:

The 2013 Nigeria demographic and health survey (NDHS) dataset was analyzed. Multiple logistic regression analysis was applied to identify determinants associated with neonatal mortality. The role of breastfeeding was examined by conducting analyses with and without adjustment for ‘breastfeeding status’. Complex sample analysis was used to control for the complex sampling design used in NDHS.

Results:

Neonatal …


Spatiotemporal Pattern Analysis Of Scarlet Fever Incidence In Beijing, China, 2005–2014, Gehendra Mahara, Chao Wang, Da Huo, Qin Xu, Fangfang Huang, Lixin Tao, Jin Guo, Kai Cao, Liu Long, Jagadish K. Chhetri, Qi Gao, Wei Wang, Quanyi Wang, Xiuhua Guo Jan 2016

Spatiotemporal Pattern Analysis Of Scarlet Fever Incidence In Beijing, China, 2005–2014, Gehendra Mahara, Chao Wang, Da Huo, Qin Xu, Fangfang Huang, Lixin Tao, Jin Guo, Kai Cao, Liu Long, Jagadish K. Chhetri, Qi Gao, Wei Wang, Quanyi Wang, Xiuhua Guo

Research outputs 2014 to 2021

Objective:

To probe the spatiotemporal patterns of the incidence of scarlet fever in Beijing, China, from 2005 to 2014.

Methods:

A spatiotemporal analysis was conducted at the district/county level in the Beijing region based on the reported cases of scarlet fever during the study period. Moran’s autocorrelation coefficient was used to examine the spatial autocorrelation of scarlet fever, whereas the Getis-Ord Gi* statistic was used to determine the hotspot incidence of scarlet fever. Likewise, the space-time scan statistic was used to detect the space-time clusters, including the relative risk of scarlet fever incidence across all settings.

Results:

A total of …


Changes In The Plasma Proteome At Asymptomatic And Symptomatic Stages Of Autosomal Dominant Alzheimer's Disease, Julia Muenchhoff, Anne Poljak, Anbupalam Thalamuthu, Veer Gupta, Pratishtha Chatterjee, Mark Raftery, Colin Masters, John Morris, Randall Bateman, Anne Fagan, Ralph Martins, Perminder Sachdev Jan 2016

Changes In The Plasma Proteome At Asymptomatic And Symptomatic Stages Of Autosomal Dominant Alzheimer's Disease, Julia Muenchhoff, Anne Poljak, Anbupalam Thalamuthu, Veer Gupta, Pratishtha Chatterjee, Mark Raftery, Colin Masters, John Morris, Randall Bateman, Anne Fagan, Ralph Martins, Perminder Sachdev

Research outputs 2014 to 2021

The autosomal dominant form of Alzheimer's disease (ADAD) is far less prevalent than late onset Alzheimer's disease (LOAD), but enables well-informed prospective studies, since symptom onset is near certain and age of onset is predictable. Our aim was to discover plasma proteins associated with early AD pathology by investigating plasma protein changes at the asymptomatic and symptomatic stages of ADAD. Eighty-one proteins were compared across asymptomatic mutation carriers (aMC, n = 15), symptomatic mutation carriers (sMC, n = 8) and related noncarriers (NC, n = 12). Proteins were also tested for associations with cognitive measures, brain amyloid deposition and glucose …


A Randomized Controlled Trial Of Very Early Rehabilitation In Speech After Stroke, Erin Godecke, Elizabeth Armstrong, Tapan Rai, Sandy Middleton, Natalie Ciccone, Anne Whitworth, Miranda Rose, Audrey Holland, Fiona Ellery, Graeme Hankey, Dominique Cadilhac, Julie Bernhardt Jan 2016

A Randomized Controlled Trial Of Very Early Rehabilitation In Speech After Stroke, Erin Godecke, Elizabeth Armstrong, Tapan Rai, Sandy Middleton, Natalie Ciccone, Anne Whitworth, Miranda Rose, Audrey Holland, Fiona Ellery, Graeme Hankey, Dominique Cadilhac, Julie Bernhardt

Research outputs 2014 to 2021

Rationale:

The efficacy of rehabilitation therapy for aphasia caused by stroke is uncertain.

Aims and hypothesis:

The Very Early Rehabilitation of Speech (VERSE) trial aims to determine if intensive prescribed aphasia therapy (VERSE) is more effective and cost saving than non-prescribed, intensive (usual care-plus) and non-intensive usual care (UC) therapy when started within 15 days of stroke onset and continued daily over four weeks. We hypothesize that aphasia therapy when started very early after stroke and delivered daily could enhance recovery of communication compared with UC.

Sample size estimates:

A total of 246 participants (82 per arm) will provide 80% …


Sources, Incidence And Effects Of Non-Physical Workplace Violence Against Nurses In Ghana, Issac Boafo, Peter Hancock, Eyal Gringart Jan 2016

Sources, Incidence And Effects Of Non-Physical Workplace Violence Against Nurses In Ghana, Issac Boafo, Peter Hancock, Eyal Gringart

Research outputs 2014 to 2021

Aim

To document the incidence, sources and effects of workplace verbal abuse and sexual harassment against Ghanaian nurses.

Methods

A cross-sectional study was conducted in Ghana from 2013–2014 which surveyed 592 professional nurses and midwives working in public hospitals in Ghana using the health sector violence questionnaire.

Results

The majority of participants were females (80%). The average age of participants was 31·76 years and the average number of years practising as nurse was 7·38. Twelve per cent of the participants experienced at least one incident of sexual harassment and 52·2% were exposed to verbal abuse. The majority of perpetrators of …


1h-Nmr Urinary Metabolomic Profiling For Diagnosis Of Gastric Cancer, Angela W. Chan, Pascal Mercier, Daniel Schiller, Robert Bailey, Sarah Robbins, Dean T. Eurich, Michael B. Sawyer, David Broadhurst Jan 2016

1h-Nmr Urinary Metabolomic Profiling For Diagnosis Of Gastric Cancer, Angela W. Chan, Pascal Mercier, Daniel Schiller, Robert Bailey, Sarah Robbins, Dean T. Eurich, Michael B. Sawyer, David Broadhurst

Research outputs 2014 to 2021

Background:

Metabolomics has shown promise in gastric cancer (GC) detection. This research sought to identify whether GC has a unique urinary metabolomic profile compared with benign gastric disease (BN) and healthy (HE) patients.

Methods:

Urine from 43 GC, 40 BN, and 40 matched HE patients was analysed using 1H nuclear magnetic resonance (1H-NMR) spectroscopy, generating 77 reproducible metabolites (QC-RSD < 25%). Univariate and multivariate (MVA) statistics were employed. A parsimonious biomarker profile of GC vs HE was investigated using LASSO regularised logistic regression (LASSO-LR). Model performance was assessed using Receiver Operating Characteristic (ROC) curves.

Results:

GC displayed a clear discriminatory biomarker profile; the BN profile overlapped with GC and HE. LASSO-LR identified …


China Suboptimal Health Cohort Study: Rationale, Design And Baseline Characteristics, Youxin Wang, Siqi Ge, Yuxiang Yan, Anxin Wang, Zhongyao Zhao, Xinwei Yu, Jing Qui, Mohamed Ali Alzain, Hao Wang, Honghong Fang, Qing Gao, Manshu Song, Jie Zhang, Yong Zhou, Wei Wang Jan 2016

China Suboptimal Health Cohort Study: Rationale, Design And Baseline Characteristics, Youxin Wang, Siqi Ge, Yuxiang Yan, Anxin Wang, Zhongyao Zhao, Xinwei Yu, Jing Qui, Mohamed Ali Alzain, Hao Wang, Honghong Fang, Qing Gao, Manshu Song, Jie Zhang, Yong Zhou, Wei Wang

Research outputs 2014 to 2021

Background:

Suboptimal health status (SHS) is a physical state between health and disease, characterized by the perception of health complaints, general weakness, chronic fatigue and low energy levels. SHS is proposed by the ancient concept of traditional Chinese medicine (TCM) from the perspective of preservative, predictive and personalized (precision) medicine. We previously created the suboptimal health status questionnaire 25 (SHSQ-25), a novel instrument to measure SHS, validated in various populations. SHSQ-25 thus affords a window of opportunity for early detection and intervention, contributing to the reduction of chronic disease burdens.

Methods/design:

To investigate the causative effect of SHS in non-communicable …


A Survey Of Knowledge, Attitudes, And Practices In Relation To Mosquitoes And Mosquito-Borne Disease In Western Australia, Abbey Potter, Andrew Jardine, Peter J. Neville Jan 2016

A Survey Of Knowledge, Attitudes, And Practices In Relation To Mosquitoes And Mosquito-Borne Disease In Western Australia, Abbey Potter, Andrew Jardine, Peter J. Neville

Research outputs 2014 to 2021

On average, more than 1,000 individuals will acquire a mosquito-borne disease in Western Australia (WA) each year. Knowledge, attitudes, and practices (KAP) in relation to mosquitoes and mosquito-borne disease have not yet been investigated within Australia. A randomized telephone survey of 2,500 households across 12 regions in WA was undertaken between February and May 2014. The aim of the survey was to obtain baseline KAP data surrounding mosquitoes and mosquito-borne diseases in different regions of WA, across a range of age groups and between males and females. The results of this survey indicate that the majority of respondents are aware …


The Emotional Intelligence Of Registered Nurses Commencing Critical Care Nursing, Yvette Nagel, Amanda Towell, Elzabe Nel, Fiona Foxall Jan 2016

The Emotional Intelligence Of Registered Nurses Commencing Critical Care Nursing, Yvette Nagel, Amanda Towell, Elzabe Nel, Fiona Foxall

Research outputs 2014 to 2021

Background: Critical care is described as complex, detailed healthcare in a unique, technologically rich environment. Critical care nursing requires a strong knowledge base and exceptional clinical and technological skills to cope in this demanding environment. Many registered nurses (RNs) commencing work in these areas may lack resilience, and because of the stress of the critical care environment, coping mechanisms need to be developed. To prevent burnout and to enable critical care nurses to function holistically, emotional intelligence (EI) is essential in the development of such coping mechanisms.

Objective: The aim of this study was to describe the EI …


Periodization Strategies In Older Adults: Impact On Physical Function And Health, Jennifer Conlon, Greg Haff, James J. Tufano, Robert Newton Jan 2016

Periodization Strategies In Older Adults: Impact On Physical Function And Health, Jennifer Conlon, Greg Haff, James J. Tufano, Robert Newton

Research outputs 2014 to 2021

Purpose

This study compared the effect of periodized versus nonperiodized (NP) resistance training (RT) on physical function and health outcomes in older adults.

Methods

Forty-one apparently healthy untrained older adults (women = 21, men = 20; 70.9 ± 5.1 yr; 166.3 ± 8.2 cm; 72.9 ± 13.4 kg) were recruited and randomly stratified to a NP, block periodized, or daily undulating periodized training group. Outcome measures were assessed at baseline and after a 22-wk × 3 d·wk−1 RT intervention, including; anthropometrics, body composition, blood pressure and biomarkers, maximal strength, functional capacity, balance confidence, and quality of life.

Results

Thirty-three …


Goal Fluency, Pessimism And Disengagement In Depression, Joanne M. Dickson, Nicholas Moberly, Christian O'Dea, Matt Field Jan 2016

Goal Fluency, Pessimism And Disengagement In Depression, Joanne M. Dickson, Nicholas Moberly, Christian O'Dea, Matt Field

Research outputs 2014 to 2021

Despite the development of prominent theoretical models of goal motivation and its importance in daily life, research has rarely examined goal dysregulation processes in clinical depression. Here we aimed to investigate problematic aspects of goal regulation in clinically depressed adults, relative to controls. Depressed participants (n = 42) were recruited from two Improving Access to Psychological Therapy clinics in north-west England. Control participants (n = 51) were recruited from the same region. Participants generated personal approach goals (e.g., improve my marathon time) and avoidance goals (e.g., avoid getting upset over little things) and completed self-report measures of goal attainment likelihood …


Motor Subtype As A Predictor Of Future Working Memory Performance In Idiopathic Parkinson's Disease, Andrew R. Johnson, Romola S. Bucks, Robert T. Kane, Meghan G. Thomas, Natalie Gasson, Andrea M. Loftus Jan 2016

Motor Subtype As A Predictor Of Future Working Memory Performance In Idiopathic Parkinson's Disease, Andrew R. Johnson, Romola S. Bucks, Robert T. Kane, Meghan G. Thomas, Natalie Gasson, Andrea M. Loftus

Research outputs 2014 to 2021

Parkinson’s disease is a progressive neurodegenerative disorder associated with reduced spatial and verbal working memory ability. There are two established motor subtypes of PD, tremor dominant (TD) and postural instability and gait difficulty (PIGD). This study used structural equation modelling to explore the longitudinal relationship between the two subtypes and working memory assessed at a 2-year follow-up. The study comprised 84 males and 30 females (N = 114), aged between 39 and 85 (M = 64.82, SD = 9.23) with confirmed PD. There was no significant relationship between motor subtype at Time 1 and working memory at Time 2. Postural …


Developing And Evaluating Complex Interventions: Enhancing The Role Of Qualitative Research, Lisa Whitehead, Marie Crowe, Carol Bugge, Kirsten Coppell Jan 2016

Developing And Evaluating Complex Interventions: Enhancing The Role Of Qualitative Research, Lisa Whitehead, Marie Crowe, Carol Bugge, Kirsten Coppell

Research outputs 2014 to 2021

The use of qualitative research methods alongside randomized controlled trials of health-care interventions have the potential to contribute to the development and evaluation of both complex and other health interventions. Qualitative evaluations of interventions are rarely reported but can provide insight into the intervention process, and the feasibility and acceptability of the intervention, to improve and adapt interventions.


Drug Use Monitoring In Australia: An Expansion Into The Pilbara, Natalie Gately, Suzanne Ellis, Robyn Morris Jan 2016

Drug Use Monitoring In Australia: An Expansion Into The Pilbara, Natalie Gately, Suzanne Ellis, Robyn Morris

Research outputs 2014 to 2021

The relationship between alcohol, illicit drugs and offending is complex and dynamic. Substance misuse both nationally and internationally has been found to be prevalent in detained populations (Bennett & Holloway 2007, Pernanen, Cousineau, Brochu & Sun 2002, Sweeney & Payne 2012). With the cost of crime in Australia estimated to be $36 billion per annum (AIC 2009), it is important to establish some of the links that, if addressed, may reduce the level of commissions of crime and increase the wellbeing of Australians.