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Transvaginal Needle Versus Laparoscopic Ovarian Drilling In Drug-Resistant Polycystic Ovary Syndrome: A Randomized, Controlled Study, Ayman E. Soliman, Heba M. Abou-Shady, Medhat E. Helmy, Nabih I. El-Khouly, Saied A. Saleh
Transvaginal Needle Versus Laparoscopic Ovarian Drilling In Drug-Resistant Polycystic Ovary Syndrome: A Randomized, Controlled Study, Ayman E. Soliman, Heba M. Abou-Shady, Medhat E. Helmy, Nabih I. El-Khouly, Saied A. Saleh
Menoufia Medical Journal
Objective The aim of this study was to evaluate the outcome of ovarian needle drilling using transvaginal ultrasound guidance as an alternative to the traditional laparoscopic electrosurgical drilling for patients with polycystic ovary syndrome (PCOS). Background Ovarian drilling has been established as a treatment for drug-resistant PCOS. Patients and methods The study comprised 84 patients with PCOS who are resistant to ovulation induction using clomiphene citrate. The patients were randomly divided into two groups; in the first group of 42 patients ovarian needle drilling was done using transvaginal ultrasound guidance, whereas in the other group of 42 patients laparoscopic electrosurgery …
The Outcome Of Induced Labor After Oxytocin Infusion Discontinuation In The Active Phase, Ahmed N. Eissa, Alaa El-Din El-Halaby, Rania A. Tahoon, Tarek M. Sayyed
The Outcome Of Induced Labor After Oxytocin Infusion Discontinuation In The Active Phase, Ahmed N. Eissa, Alaa El-Din El-Halaby, Rania A. Tahoon, Tarek M. Sayyed
Menoufia Medical Journal
Objective The objective was to determine whether discontinuation of oxytocin infusion after established active phase of induced labor gives good obstetric outcome without any adverse maternal and neonatal effect. Background Oxytocin is one of the most widely drugs used in induction of labor. Continuous infusion of oxytocin after establishment of the active phase of labor may lead to uterine atony and postpartum hemorrhage. Therefore, we should stop oxytocin infusion once the active phase has started. Patients and methods A total of 90 pregnant women who required labor induction and fulfilled the criteria of the study population were enlisted in this …
Immune Checkpoint Blockade In Malignant Lymphomas, Amira El-Desouky, Amira Fouad, Dina El-Habashy, Eman A. Razek, Suzan El-Hassanin
Immune Checkpoint Blockade In Malignant Lymphomas, Amira El-Desouky, Amira Fouad, Dina El-Habashy, Eman A. Razek, Suzan El-Hassanin
Menoufia Medical Journal
Objective The objective of this study was to identify the emerging role of immune checkpoint inhibitors in lymphomas. Materials and methods Medline databases (Google Scholar, PubMed, http://www.ekb.eg) and all materials available on the Internet from 2008 till 2015. The initial search presented 10 articles of which seven have met the inclusion criteria. These articles studied the emerging role of immune checkpoint inhibitors in lymphoma. Studies that did not fulfill were excluded. Study quality assessment included whether ethical approval was gained, eligibility criteria specified, appropriate controls, adequate information, and defined assessment measures have been undertaken. Comparisons were made by a …
Traumatic Brain Injury: Serum S-100b Protein Measurement Related To Neuroradiological Findings, Ahmed A. Metwally, Amany S. Ammar, Mohammed M. El-Mashad, Nagwa M. Doha
Traumatic Brain Injury: Serum S-100b Protein Measurement Related To Neuroradiological Findings, Ahmed A. Metwally, Amany S. Ammar, Mohammed M. El-Mashad, Nagwa M. Doha
Menoufia Medical Journal
Objective The aim of this study was to estimate the level of S-100B protein as a biological marker and to assess its sensitivity in the detection and prediction of outcome of traumatic brain injury (TBI) patients compared with radiological and clinical scores. Background TBI has a tremendous impact on public health. S-100B protein increases in cases of TBI and does not increase in nonbrain injuries. S-100B has been found to correlate with the severity of head injury. Patients and methods The study was a prospective, randomized, controlled study. Forty critical patients were divided into two groups; group I had 20 …
Scalpel Versus Diathermy Skin Incisions In Cesarean Sections, Abdelhameed E. Shaheen, Ahmed H. Aish, Allaaeldin F. Elhalaby, Hamed E. Ellakwa, Nasser K. Abdelaal
Scalpel Versus Diathermy Skin Incisions In Cesarean Sections, Abdelhameed E. Shaheen, Ahmed H. Aish, Allaaeldin F. Elhalaby, Hamed E. Ellakwa, Nasser K. Abdelaal
Menoufia Medical Journal
Objective The aim was to compare the use of diathermy versus scalpel in making skin incision during cesarean section to judge the variations in postoperative pain, incision time, incisional blood loss, operative time, wound healing, and wound complications. Background Surgical scalpels are traditionally used for making skin incisions during cesarean delivery. The evolutions in electrosurgical devices bring an alternative method for making skin incision by the usage of cutting diathermy. Patients and methods This was a prospective, randomized comparative study conducted during the period from March 2016 to February 2017 on 200 patients; 100 patients had skin incisions using the …
Misoprostol And Tranexamic Acid Role In Reducing Blood Loss During The Elective Cesarean Section, Alaa Ma El-Gayed, Mehany Ma El-Sttar, Ragab M. Dawood, Yehia Z. El-Sayd Ghnnam
Misoprostol And Tranexamic Acid Role In Reducing Blood Loss During The Elective Cesarean Section, Alaa Ma El-Gayed, Mehany Ma El-Sttar, Ragab M. Dawood, Yehia Z. El-Sayd Ghnnam
Menoufia Medical Journal
Objective To compare the efficacy of using misoprostol alone or in combination with tranexamic acid (TA) in reducing blood loss during elective cesarean section (CS). Background Normal blood loss during labor is ∼300–400 ml. Blood loss more than 500 ml following vaginal birth or greater than 1000 ml following CS means postpartum hemorrhage. Patients and methods A prospective randomized comparative clinical study was conducted on 150 patients who were divided into two groups: group A (75 patients) received misoprostal 600 mcg rectally before the incision, and group B (75 patients) received misoprostal 600 mcg rectally and 1-g TA slowly intravenously …
Predictors Of Effective Fluid Therapy In The Intensive Care Unit, Essam A. Ghoniem, Heba M. Naguib, Wesam El-Din Sultan
Predictors Of Effective Fluid Therapy In The Intensive Care Unit, Essam A. Ghoniem, Heba M. Naguib, Wesam El-Din Sultan
Menoufia Medical Journal
Objective Static and dynamic indices predicting fluid responsiveness (FR) in critically ill patients, physiological basis, advantages, disadvantages, and cut-off values for each method. Materials and methods Medical textbooks, Medscape, PubMed, and the ScienceDirect. The databases were searched from the start date of the database and a search was performed on May 2016 with no language restriction. The initial search found 25 articles of which 15 met the inclusion criteria that address preload responsiveness, FR, and cardiac output monitoring devices. Extraction was carried out depending on the validity, quality, and originality of the selected reviews and studies; and the focus was …
Fluid Responsiveness In Hemodynamically Unstable Patients: A Systematic Review, Abdallah Khattab, Hatem A. Atallah, Khaled M. Gaballah
Fluid Responsiveness In Hemodynamically Unstable Patients: A Systematic Review, Abdallah Khattab, Hatem A. Atallah, Khaled M. Gaballah
Menoufia Medical Journal
Objective To evaluate the usefulness of different hemodynamic measurements in the detection of fluid responsiveness (FR) among patients with hemodynamic instability. Backgrounds Close hemodynamic monitoring of unstable patients' response to volume expansion is a central component of intensive care. Previous reports demonstrated that only 50% of patients respond to fluid administration with an increase in stroke volume or cardiac output. Data sources A computer literature search of PubMed, Scopus, and Cochrane Central was conducted. Study selection Records were screened for eligible studies according to the predetermined inclusion criteria. Data extraction Data were extracted and synthesized using standardized tables. Data synthesis …
Magnesium Sulfate Versus Dexmedetomidine As Adjuvants To Bupivacaine In Postoperative Epidural Analgesia After Total Knee Replacement, Abd-Elrahman A. Ahmad, Amany A. Sultan, Ashraf M. Eskandar, Esam Ae Esmaeil, Magda F. Yehia
Magnesium Sulfate Versus Dexmedetomidine As Adjuvants To Bupivacaine In Postoperative Epidural Analgesia After Total Knee Replacement, Abd-Elrahman A. Ahmad, Amany A. Sultan, Ashraf M. Eskandar, Esam Ae Esmaeil, Magda F. Yehia
Menoufia Medical Journal
Objective The purpose of this study was to evaluate magnesium sulfate (MgSO4) or dexmedetomidine combined with bupivacaine versus bupivacaine for postoperative epidural analgesia in patients undergoing total knee replacement (TKR). Background Epidural analgesia after TKR is an effective widely used technique. Plain bupivacaine is one of the commonly used drugs. Several adjuvants are emerging to enhance its analgesic properties and decrease possible side effects. MgSO4 and dexmedetomidine are promising. Patients and methods This prospective randomized controlled study included 60 patients undergoing TKR who were randomized into three groups for postoperative epidural analgesia: group B bupivacaine, group BM bupivacaine plus …
Noninvasive Versus Invasive Ventilation In Weaning Of Patients With Type 2 Respiratory Failure, Mahmoud Nz Ghoneum, Mohamed Hi Afifi, Sami Sa El_Dahdouh, Yasser I. Fathy
Noninvasive Versus Invasive Ventilation In Weaning Of Patients With Type 2 Respiratory Failure, Mahmoud Nz Ghoneum, Mohamed Hi Afifi, Sami Sa El_Dahdouh, Yasser I. Fathy
Menoufia Medical Journal
Objective The aim of this study was to investigate noninvasive ventilation (NIV) effectiveness as an early weaning technique in difficult-weaning patients with chronic hypercapnic respiratory failure. Background Although invasive ventilation is effective, it is associated with complications like ventilator-associated pneumonia. Ventilator-associated pneumonia has been associated with increased morbidity and mortality. So, minimizing the duration of invasive mechanical support without increasing the risk of adverse events is an important goal. NIV may provide a means of reducing the duration of invasive mechanical support for patients with respiratory failure. Patients and methods A prospective, randomized controlled study was conducted on 40 mechanically …
Effect Of Umbilical Cord Entanglement On Pregnancy Outcomes Menoufia Medical Journal, Hesham A. Ammar, Mohamed F. El-Kherbawy, Tarek M. Sayyed, Zakaria F. Sanad
Effect Of Umbilical Cord Entanglement On Pregnancy Outcomes Menoufia Medical Journal, Hesham A. Ammar, Mohamed F. El-Kherbawy, Tarek M. Sayyed, Zakaria F. Sanad
Menoufia Medical Journal
Objective This work aimed to study the effect of umbilical cord entanglement on the mode of delivery. In addition, this study aimed to evaluate the sensitivity of ultrasound with Doppler for the detection of nuchal entanglement of the umbilical cord. Background The umbilical cord is a narrow tube-like structure that connects the developing baby to the placenta. Most of the nuchal cords diagnosed in early pregnancy become spontaneously uncoiled. Materials and methods This cohort study included 300 pregnant laboring women with singleton pregnancies more than 37 weeks. This study was carried out from January 2016 to February 2017 in the …
Comparison Study Between Nifedipine And Progesterone As Maintenance Tocolysis After Arrested Preterm Labor, Ahmed M. Nofal, Alaa M. Abdelgaied, Elham F. El-Sisi, Ragab M. Dawood
Comparison Study Between Nifedipine And Progesterone As Maintenance Tocolysis After Arrested Preterm Labor, Ahmed M. Nofal, Alaa M. Abdelgaied, Elham F. El-Sisi, Ragab M. Dawood
Menoufia Medical Journal
Objective The aim was to compare the efficacy and safety of nifedipine and progesterone for maintenance tocolysis after arrested preterm labor and their perinatal outcomes. Background Preterm birth (before 37 completed weeks of gestation) is a 'major cause of death' and a significant cause of long-term loss of human potential. Maintenance tocolysis is continued tocolysis after arrested preterm labor to prevent the recurrence of preterm labor pains. Patients and methods A prospective randomized comparative clinical study was carried out on 66 pregnant women who had preterm labor (six cases lost to follow-up) and attended the Obstetrics and Gynecology Outpatient Clinic …
Plasma Levels Of Von Willebrand Factor In Maintenance Hemodialysis Patients: Its Relation To Vascular Access Thrombosis, Amira M. E. Yousuf, Belal A. Montaser, Hassan Abd El-Hady, Khaled M. A. El-Zorkany, Mahmoud A. Kora
Plasma Levels Of Von Willebrand Factor In Maintenance Hemodialysis Patients: Its Relation To Vascular Access Thrombosis, Amira M. E. Yousuf, Belal A. Montaser, Hassan Abd El-Hady, Khaled M. A. El-Zorkany, Mahmoud A. Kora
Menoufia Medical Journal
Objective The aim of this study was to assess von Willebrand factor (VWF) plasma levels in patients under maintenance hemodialysis (HD) to determine its role in the occurrence of vascular access thrombosis (VAT) in such patients. Background HD process is associated with increasing thrombotic trend especially owing to platelets and clotting factor activation. Vascular access complications increase morbidity and contribute to 20–25% of all hospitalizations in HD patients, of which ~ 85% of these cases are because of thrombosis. VWF is an important component of the hemostatic system and a hypercoagulability state biomarker. Patients and methods This case–control study was …
Therapeutic Effects Of Human Stem Cells In Experimentally Induced Acute Kidney Injury In Rats, Ahmed M. Zahran, Ahmed R. Tawfiq, Hussain M. Hussain Kholaif, Mahmoud A. El-Aziz Kora, Yahya M. Naguib Abd El-Salam
Therapeutic Effects Of Human Stem Cells In Experimentally Induced Acute Kidney Injury In Rats, Ahmed M. Zahran, Ahmed R. Tawfiq, Hussain M. Hussain Kholaif, Mahmoud A. El-Aziz Kora, Yahya M. Naguib Abd El-Salam
Menoufia Medical Journal
Objective The aim of this study was to evaluate the effect of stem cell therapy in drug-induced acute kidney injury in rats. Background Acute kidney injury (AKI) is defined as a rapid decrease in renal functions within few days; thus drug-induced AKI is a frequent entity in clinical medicine. Stem cell therapy provides a hopeful prospective for injured tissues and for repairing damaged organs. Materials and methods A total of 30 male Swiss albino rats were used in the present study. The animals were randomly divided into three groups. Group I: control group (10 rats). Group II: AKI group (10 …
Diagnostic Value Of Serum Dickkopf-1 As A Predictor Of Hepatocellular Carcinoma In Patients With Liver Cirrhosis, Ahmed E. El-Shandalaty, Ashraf G. Dala, Mohammed H. Badr, Mona S. Habib
Diagnostic Value Of Serum Dickkopf-1 As A Predictor Of Hepatocellular Carcinoma In Patients With Liver Cirrhosis, Ahmed E. El-Shandalaty, Ashraf G. Dala, Mohammed H. Badr, Mona S. Habib
Menoufia Medical Journal
Objective The aim of this study was to evaluate the significance of Dickkopf-1 (DKK-1) as a tumor marker for the diagnosis of hepatocellular carcinoma (HCC) in cirrhotic patients. Background HCC is a major health problem and its prognosis still remains dismal. Patients and methods This cross-sectional study included 50 cirrhotic patients with HCC, 50 cirrhotic patients without HCC, and 20 healthy age-matched and sex-matched participants as controls. All patients and controls were subjected to the following: full history taking, full clinical examination, and investigations as complete blood count, kidney function tests, liver function tests, serum α-fetoprotein (AFP), serum DKK-1, abdominal …
Study Of Serum Endotoxin In Patients With Liver Cirrhosis With And Without Hepatic Encephalopathy, Ayman M. El-Lehleh, Ayman A. Algamal, Enas F. El Mezain, Rania A. El-Shazly
Study Of Serum Endotoxin In Patients With Liver Cirrhosis With And Without Hepatic Encephalopathy, Ayman M. El-Lehleh, Ayman A. Algamal, Enas F. El Mezain, Rania A. El-Shazly
Menoufia Medical Journal
Objective To study serum endotoxin in patients with liver cirrhosis with and without hepatic encephalopathy (HE). Background HE is a common complication of liver cirrhosis. Studies suggest that endotoxin and ammonia play an important role in its pathogenesis. Patients and methods This prospective study was conducted from November 2016 to May 2017 on 30 patients with liver cirrhosis without HE as group I, 30 patients with HE (group II) and 30 age-matched and sex-matched healthy individual as the control group. All were subjected to history taking, complete medical examination, and thorough laboratory and radiological investigations. Serum endotoxin was measured by …
Maternal And Neonatal Outcomes Of Placenta Accreta: A Descriptive Case Series Study, Abdelhaseeb Salaha, Mohamed A. S. Kandil, Nehal M. A. Al Gilanyb, Tarek M. Sayyeda
Maternal And Neonatal Outcomes Of Placenta Accreta: A Descriptive Case Series Study, Abdelhaseeb Salaha, Mohamed A. S. Kandil, Nehal M. A. Al Gilanyb, Tarek M. Sayyeda
Menoufia Medical Journal
Objective The objective of this study was to evaluate maternal and neonatal outcomes of placenta accreta. Background Placenta accreta is the leading cause of maternal and neonatal morbidity and mortality. Patients and methods This descriptive case series study included 40 pregnant women with placenta accreta and was carried out at Department of Obstetrics and Gynecology of Menoufia University Hospitals for 10 months. The study cohort included all admitted pregnant women with the diagnosis of placenta previa accreta whether presenting with or without vaginal bleeding after 28 weeks of gestation confirmed by ultrasound scan. Data were collected and confirmed by positive …
Evaluation Of Femtosecond Laser-Assisted Implantation Of Intracorneal Ring Segments In Cases Of Keratoconus, Abd El-Rahman El-Sebaey, Alia M. Nagy, Farid M. W. Farid
Evaluation Of Femtosecond Laser-Assisted Implantation Of Intracorneal Ring Segments In Cases Of Keratoconus, Abd El-Rahman El-Sebaey, Alia M. Nagy, Farid M. W. Farid
Menoufia Medical Journal
Objective To evaluate the clinical outcomes after implantation of the intracorneal ring segments (ICRSs) by means of femtosecond laser technology in eyes with keratoconus. Background Corneal modeling by inserting intrastromal implants has been proposed and investigated as an alternative treatment option in corneal ectasia. Femtosecond laser technology allows the surgeon to program a corneal stromal dissection at a predetermined depth with an extremely high degree of accuracy, which avoids the potential inaccuracies of a mechanical dissection. Patients and methods A total of 35 eyes of 28 patients were included in the study. All cases presented with reduced best spectacle corrected …
Patient Satisfaction And Compliance In Family: A Comment, Beuy Joob, Viroj Wiwanitkit
Patient Satisfaction And Compliance In Family: A Comment, Beuy Joob, Viroj Wiwanitkit
Menoufia Medical Journal
No abstract provided.
Superiorly Based Septal Mucosal Flap For Endoscopic Repair Of Nasal Septal Perforation, Adel T. Atallah, Ahmad M. Hamdan, Ashraf A. El-Demerdash, Ibrahim A. Abdelshafi, Yaser A. Khalil
Superiorly Based Septal Mucosal Flap For Endoscopic Repair Of Nasal Septal Perforation, Adel T. Atallah, Ahmad M. Hamdan, Ashraf A. El-Demerdash, Ibrahim A. Abdelshafi, Yaser A. Khalil
Menoufia Medical Journal
Objective To assess the outcome of endoscopic superiorly based septal mucosal flap technique in the repair of nasal septal perforation. Background Septal perforations are a common problem with many surgical options for closure using either closed or open approach. Patients and methods This case series study included 14 patients with anterior septal perforation with idiopathic or iatrogenic etiology recruited from Otorhinolaryngology Department, Menoufia University, during the period from July 2015 to July 2017. The patients were assessed using history taking, anterior rhinoscopy, endoscopic examination, and computed tomography. Preoperative symptoms were assessed using visual analog scale. All patients were subjected to …
The Role Of Fibrinolytics In Prevention Of Adhesive Intestinal Obstruction, Alaa A. Elsesi, Asem F. Moustafa, Mohammed M. Ahmed
The Role Of Fibrinolytics In Prevention Of Adhesive Intestinal Obstruction, Alaa A. Elsesi, Asem F. Moustafa, Mohammed M. Ahmed
Menoufia Medical Journal
Objective The objective of this study was to evaluate the efficacy and safety of fibrinolytic drugs in the prevention of adhesive intestinal obstruction in high-risk patients. Background Postoperative peritoneal adhesions represent an important clinical challenge in gastrointestinal surgery. Fibrin plays an important role in postoperative adhesion formation. Resolution of the intraperitoneal fibrin deposits is essential for proper restoration of preoperative, noninflamed conditions. Patients and methods This randomized controlled trial study included 60 patients randomized into two groups (A and B). Each group included 30 patients presented with bacterial peritonitis of different causes. All patients were treated surgically. Patients in group …
Mesh Repair In Complicated Inguinal Hernia, Ahmed G. El Tatawy, Amr N. Frig, Ashraf A. Zeineldin
Mesh Repair In Complicated Inguinal Hernia, Ahmed G. El Tatawy, Amr N. Frig, Ashraf A. Zeineldin
Menoufia Medical Journal
Objective The aim of this study was to evaluate the role of mesh repair short-term outcome in adult incarcerated inguinal hernia from the point of view of availability, advantages and disadvantages. Background Hernia is the most frequent abdominal surgery. The standard treatment of inguinal hernia is hernioplasty with mesh repair; we aimed to evaluate the short-term complications after mesh repair in incarcerated inguinal hernia in emergency. Patients and methods This study was carried out on 20 consecutive adult men in Menoufia University Faculty of Medicine and Dessouq General Hospital; all of them presented with symptoms of irreducible inguinal hernia from …
Factors Affecting Success Rate Of Endoscopic Retrograde Cholangiopancreatography In Malignant Obstructive Jaundice, Hamed A. Khodeer, Hatem M. Sultan, Tarek M. Rageh
Factors Affecting Success Rate Of Endoscopic Retrograde Cholangiopancreatography In Malignant Obstructive Jaundice, Hamed A. Khodeer, Hatem M. Sultan, Tarek M. Rageh
Menoufia Medical Journal
Objective The aim of the study was to assess the success of endoscopic retrograde cholangiopancreatography (ERCP) for malignant obstructive jaundice using laboratory and radiological investigation. Background ERCP is a diagnostic and palliative treatment, which is used as the standard of investigation for patients with malignant obstructive jaundice; however, it failed in some patients. The prediction for success will be useful in the decision of management plan for patients with malignant obstructive jaundice and time and costs for patients and even countries. Patients and methods Collected laboratory investigation and radiological data for 20 patients presenting with malignant obstructive jaundice are included …
One-Stage Versus Multiple-Stage Surgery In The Management Of Left Colorectal Emergencies, Ashraf A. E. Z. El-Din, Hossam A. E. El Fol, Tamer A. Sultan, Waleed M. Allam
One-Stage Versus Multiple-Stage Surgery In The Management Of Left Colorectal Emergencies, Ashraf A. E. Z. El-Din, Hossam A. E. El Fol, Tamer A. Sultan, Waleed M. Allam
Menoufia Medical Journal
Objective The aim of this study was to compare between the surgical outcomes of one-stage and multiple-stage surgery in patients with left colorectal emergencies. Background Classically a primary colonic anastomosis is not performed in the emergency conditions, but recently there is a trend toward primary anastomosis aiming to avoid second hospital admission and second operation required to re-establish intestinal continuity. Patients and methods This is a prospective randomized study that included 40 patients. A total of 20 patients agreed to undergo one-stage primary anastomosis subtotal colectomy (group A). The other 20 patients underwent Hartmann's procedure (group B). Exclusion criteria were …