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Histopathological Changes Of Levator Palpaberae Superioris Muscle In Different Degrees Of Congenital Ptosis, Osama A. Al-Morsy, Ali A. Elhayes, Gamal A.R. Barakat

Menoufia Medical Journal

Objectives: To evaluate the Histopathological changes in specimens of levator palpaberae superioris muscle of patients with different degrees of congenital Ptosis. Background: Ptosis, also called blepharoptosis, is known as the drooping of the upper eyelid. Simple congenital ptosis is the most prevalent form of congenital ptosis. Levator palpebrae superioris (LPS) and Muller's muscle are two muscles of upper eyelid responsible for its elevation. The levator palpebrae superioris is a triangular-shaped muscle located in each upper eyelid. Subjects and methods: This prospective analysis included a total of 30 eyelids of patients with different degrees of ptosis eligible for the study who …

Outcomes Of Intravitreal Injection Of Ranibizumab As Primary Monotherapy For Treatment-Requiring Retinopathy Of Prematurity, Hm. El-Sobky, Hm. Marey, Am. Habib, Ag. Zaky, Rm. Ashour, Ai. Basiony

Menoufia Medical Journal

Objective: This study aims to assess structural, refractive, and biometric outcomes and safety of intravitreal ranibizumab (IVR) for treatment requiring retinopathy of prematurity (ROP) 1-year post-IVR. Background: IVR has been proposed as alternative to conventional laser photocoagulation for treatment requiring ROP in different zones to achieve better structural and functional outcomes. Methods: A prospective case series conducted in in Menoufia university hospitals, Menoufia governorate, Egypt during the period from January 2021 to December 2022. Premature infants who met the eligibility criteria with type 1 pre-threshold ROP, threshold ROP and Aggressive-ROP (A-ROP) received IVR of 0.25mg (0.025 ml). Postoperatively, patients were …

Using Margin-Reflex Distance Versus Levator Function In Diagnosing Congenital Blepharoptosis, Sameh S. Mandour, Abdelkhalik Elsaadany, Salma E.H. Elsaify, Dalia S. Saif

Menoufia Medical Journal

Objective

To compare the different methods of clinical evaluation of upper eyelid congenital blepharoptosis and discuss the utility of margin-reflex distance (MRD1) over levator muscle function (LF) in choosing the appropriate surgical procedure for congenital blepharoptosis correction.

Background

The amount of the cornea covered by the eyelid varies, resulting in visual disturbances and cosmetic problems. Surgical correction is the mainstay treatment of congenital blepharoptosis; therefore, our study uses MRD as a determinant for choosing the appropriate surgical intervention for ptosis correction.

Patients and methods

This was a prospective study conducted on 20 patients with upper eyelid ptosis based on clinical …

Association Of Chorioretinal Thickness With Chronic Kidney Disease, Adel G. Zaky, Ahmed I. Basiony, Noha M. G. Dwidar, Sherry N. A. Youssef

Menoufia Medical Journal

Background The eye shares striking structural, developmental, and genetic pathways with the kidney, suggesting that kidney disease and ocular disease may be closely linked. Objectives To assess retinal and choroidal thickness in patients with chronic kidney disease (CKD) using spectral-domain optical coherence tomography. Patients and methods This was a cross-sectional study conducted at Menoufia University Hospital Ophthalmology Department on 144 eyes of 72 CKD patients, who were divided into three groups according to the stage of CKD as follows: group 1: CKD stage 1–2, estimated glomerular filtration rate (eGFR) more than 60 ml/min/1.73m², group 2: CKD stage 3, …

Dry Eyes After Small Incision Lenticule Extraction Versus Femtosecond-Laser In Situ Keratomileusis, Ahmed M. S. Fayed, Carmen K. Samuel, Khaled El Ghonemy

Menoufia Medical Journal

Background Patients who develop dry eyes after refractive surgery also have elevated risks of developing subsequent refractive regression and ocular surface damage. Objective To measure the level of dryness after small incision lenticule extraction (SMILE) in comparison with the level of dryness after femtosecond laser using the tear film break-up time test and Schirmer test. Patients and methods The study was conducted as a prospective (cohort) study on 52 patients who were recruited before and after the surgery from the outpatient clinic, Faculty of Medicine, Menoufia University. All participants included in this study were divided into group I, which included …

Association Between Visual Acuity And Retinal Layer Metrics In Diabetics With And Without Macular Edema, Marwa A. Zaky, Rawda A. Othman, Sameh S. Mandour

Menoufia Medical Journal

Objective The aim of the study was to investigate the correlation between the retinal layer metrics and visual acuity (VA) in diabetics with and without diabetic macular edema (DME). Background Diabetes is known to cause alterations in retinal microvasculature that progressively lead to visual impairment. In the current study, we determined the association between VA and retinal layer metrics derived from optical coherence tomography images in patients with and without DME. Patients and methods A case–control study was conducted on 216 eyes at the Department of Ophthalmology, Menoufia University Hospital. Group 1 included 40 eyes of type I diabetics, group …

Effects Of Chronic Uveitis On Pediatric Quality Of Life, Noha K. Gaber, Safaa F. Saad, Sameh S. Mandou, Shiamaa S. Soliman

Menoufia Medical Journal

Objective This study aimed to assess health-related quality of life (HR-QOL) in children with chronic uveitis. Background Pediatric uveitis is an inflammatory ocular disease that can lead to severe ocular complications. It can significantly affect the HR-QOL of children and daily function. Patients and methods In this case–control study, HR-QOL was evaluated in 20 children with chronic uveitis and 20 children without chronic uveitis. The cases were recruited from the Ophthalmology Department in Menoufia University, and controls were recruited from a school. HR-QOL was evaluated by the Pediatric Quality of Life Inventory Version 4.0 (PedsQL 4.0). Results Uveitis-related data are …

Retinal Nerve Fiber Layer Thickness Changes Following Silicone Oil Removal: Before And After 6 Months Tamponade, Adel G. Zaky, Ahmed I. Basiony, Moustafa K. Nassar, Waffa A. A. Elhady

Menoufia Medical Journal

Objectives This study aimed to evaluate the peripapillary retinal nerve fiber layer (RNFL) changes following retinal detachment repair with silicone oil (SO) tamponade by optical coherence tomography. Background SO has a well-established part in vitreoretinal surgery. With the enhancement of microsurgical strategies, it allows prolonged intraocular tamponade, and because of its optical clarity, it provides adequate postoperative assessment and good evaluation of visual acuity. Patients and methods This cross-sectional case series study was performed at two vitreoretinal centers; 30 patients underwent successful vitrectomy for primary rhegmatogenous retinal detachment with the macula of less than 1 month of using SO (5000 …

Corneal Endothelial Changes By Specular Microscopy After Uncomplicated Phacoemulsification, Abla A. Al Yamany, Afaf A. El Ashram, Esraa S. El-Ghoubashy, Noha K. Gaber

Menoufia Medical Journal

Objectives To determine the effects of phacoemulsification surgery on corneal endothelial cell density and corneal thickness in patients undergoing cataract surgery. Background Phacoemulsification cataract surgery with implantation of an intraocular lens is the most common procedure for cataract extraction, which may have several complications. Patients and methods This was a descriptive prospective study for comparative analysis of corneal endothelial changes using Tomey EM-3000 noncontact specular microscope held on selected patients with senile cataracts who attended the outpatient clinic of Menoufia Ophthalmology Center (MOC) for cataract surgery in the period from October 2021 March 2022. Cataract extraction using phacoemulsification and intraocular …

Study Of The Effect Of Prostaglandin Analogs On The Periorbita Of Glaucomatous Patients, Amr M. Awwad, Hoda M. El Sobky, Sameh S. Mandour

Menoufia Medical Journal

Objectives To present the various adverse effects of topical prostaglandin analogs on the periorbita. Background The authors studied the prostaglandin-related adverse effects on the periorbita and compared each analog in a sample of patients with glaucoma. Patients and methods A case series study was performed on the adverse effects on the periorbita noticed in glaucomatous patients who were controlled by prostaglandin in Menoufia University Hospital and Cairo Fatemic Hospital. The study was done on 100 patients aged from 18 to 75 years at outpatient clinics. Results A total of 100 patients were found to have a variety of disorders, including …

Evaluation Of Treatment Of Retinopathy Of Prematurity By Intravitreal Injection Of Ranibizumab: A Clinical Trial, Abdelhamied F. Allam, Ahmed Fayd, Mohamed S. Abdelaziz

Menoufia Medical Journal

Objectives Evaluation of treatment of type-I retinopathy of prematurity (ROP) detected by early screening of preterm infants by intravitreal injection of Ranibizumab. Background Retinopathy of prematurity is a childhood-blindness disease. Considering Ranibizumab might have a better safety profile for preterm infants, some authors shifted IVB to intravitreal injection of Ranibizumab to treat ROP. Patients and methods A clinical trial was performed between January 2021 and May 2022 in the neonatal ICU and Department of Ophthalmology, Menoufia University on 131 preterm infants. Type-I ROP cases were diagnosed and treated with intravitreal injection (IVI) of antivascular endothelial growth factor Ranibizumab 0.25 mg/0.025 …

Different Optical Coherence Tomography Parameters In Diabetic Macular Edema As Predictors Of Visual Acuity, Ahmed M. Fayed, Asmaa S.A Abu Husin, Asmaa M. Ibrahim

Menoufia Medical Journal

Objectives The aim was to evaluate the disorganized inner retinal layers, the thickness of the outer retinal layer, and central foveal thickness using spectral domain optical coherence tomography as predictors of visual acuity (VA) in patients with diabetic macular edema (DME). Data sources Medline databases (PubMed and Medscape) were searched, and all materials available in the Internet. The search was performed on January 2022. Study selection The initial search presented 120 articles. The number of studies that met the inclusion criteria was 15. The articles included both sexes, diabetic patients aged 18 years old or above and capable of giving …

Evaluation Of Retinal Thickness In Women Using Spectral-Domain Optical Coherence Tomography, Khaled Elghonemy, Marwa Zaky, Nissma M. Shaheen, Noha Khairat

Menoufia Medical Journal

Objectives To evaluate the macular, retinal nerve fiber layer (RNFL), and choroidal thickness alterations using spectral-domain optical coherence tomography (OCT) in postmenopausal, pregnant, and nonpregnant women. Background The choroid, also known as the choroidea or choroid coat, is a part of the uvea, the vascular layer of the eye. It contains connective tissues and lies between the retina and the sclera. Patients and methods A comparative study was conducted that included 75 eyes of 75 healthy women in the period from March 2021 to December 2021. They were divided into three groups: (a) nonpregnant women, (b) pregnant women, and (c) …

Comparative Study Between Difluprednate And Prednisolone Acetate After Phacoemulsification In Diabetic Patients, Ahmed M M Elsehemy, Ahmed I. Basiony, Marwa A. Zaky, Sameh S. Mandour

Menoufia Medical Journal

Objective To compare difluprednate 0.5 mg (0.05%) versus prednisolone acetate 10 mg MedCalc Software (1%) after cataract procedures in diabetic patients regarding their safety and efficacy in postoperative inflammation. Background Cataract is the world's most prevalent cause of vision loss, affecting mostly the elderly. Cataract surgery is now the sole therapy option. As a result, around eight million cataract operations are conducted each year. Furthermore, the higher life expectancy supports the likelihood of even more procedures in the coming years. Patients and methods This prospective interventional comparative research included 74 eyes of diabetic patients with cataract, attending Menoufia University Hospital …

Evaluation Of The Macula And Peripapillary Retinal Nerve Fiber Layer In Patients With Autoimmune Thyroid, Ahmed M S Fayed, Asmaa M A Ibrahim, Hytham R. Badr, Seham S. Sayed

Menoufia Medical Journal

Objective To evaluate the macula and peripapillary retinal nerve fiber layer (RNFL) in patients with autoimmune thyroid compared with normal individuals using spectral domain optical coherence tomography. Background Thyroid eye disease is a complex orbital inflammatory disease that can be sight threatening. The acute progression of the disease is an ocular emergency, particularly optic nerve compression. Patients and methods A cross-sectional study was conducted on 32 eyes with autoimmune thyroid disease who were diagnosed by the Department of Endocrinology, Menoufia University Hospital, and examined by Ophthalmology Department, Menoufia University Hospital, Egypt, during the period study from March 2020 till October …

Endoscopic Dacryocystorhinostomy With Ologen Implant, Ali Abd El-Hakam A. El-Hayes, Ashraf A. Eldemerdash, Hesham M. El Mazar, Sameh S. Mandour

Menoufia Medical Journal

Background Chronic dacryocystitis is an inflammatory disorder of the lacrimal sac that is accompanied by nasolacrimal-duct obstruction. Watering and discharge are the most common symptoms. Objectives To compare the effectiveness of endoscopic dacryocystorhinostomy (DCR) with ologen implant versus endoscopic DCR with silicone-tube implantation. Patients and methods A prospective comparative study was conducted to evaluate the effectiveness of endoscopic DCR with ologen implant versus endoscopic DCR with silicone-tube implantation. A total of 40 patients underwent primary endoscopic DCR surgery from March 2020 to March 2021. A total of 20 cases underwent endoscopic DCR using ologen implant (group A) and the other …

Effect Of Collagen Cross-Linking On Corneal Endothelial Cell Count In Keratoconus Patients Using Specular Microscopy, Amin F. Ellakwa, Asmaa M. Ibrahim, Esraa S. El-Ghoubashy, Omnia M S Elsaka

Menoufia Medical Journal

Objectives To compare endothelial cell density (CD) and morphology in the peripheral cornea before and after corneal cross-linking (CXL). Background Corneal CXL has been acknowledged as an effective method for halting the progression of keratoconus by photosensitization of riboflavin activated by ultraviolet A. For this surgical indication, it is usually recommended that the preoperative corneal thickness is at least 400 μm to prevent corneal endothelial cell damage caused by ultraviolet A irradiation. It has been reported that even 5 years after CXL, the endothelial CD did not change significantly at any postoperative interval. Patients and methods This study evaluated 40 …

Role Of Fenofibrate In Reduction Of Central Macular Thickness In Diabetic Macular Edema, Ahmed I. Basiony, Amany M S. El-Banna, Moataz F. El-Sawy, Shimaa K. Zewain

Menoufia Medical Journal

Objective To study the benefit of addition of oral fenofibrate to the standard management of diabetic macular edema (DME) regarding central macular thickness (CMT) and visual function. Background DME is the commonest cause of vision loss in diabetes. Systemic therapy for DME largely meant control of diabetes, hypertension, and lipid levels. A revival in the use of systemic medication for a local condition caused by a systemic disease has occurred recently with hypolipidemic drugs, namely, atorvastatin and fenofibrate. Patients and methods Our study was a randomized controlled trial. It included 100 eyes of patients with type-2 diabetes complicated with DME. …

Effect Of Rheumatoid Arthritis Treatment On The Posterior Segment Of The Eye, Abdelkawy Moghazy, Ahmed S. Fayed, Heba A. R. Rizk, Moataz El-Sawy

Menoufia Medical Journal

Objective The aim of the study was to evaluate the influence of rheumatoid arthritis (RA) treatment on the posterior segment of the eye using spectral-domain optical coherence tomography. Background RA is a common chronic autoimmune systemic inflammatory disease that primarily affects mainly small joints. It may affect many parts of the eye, such as conjunctiva, cornea, sclera, uvea, choroid, and retina. Patients and methods The study included 44 RA patients (22 on methotrexate and 22 on etanercept), and 21 healthy controls. Results A significant increase in choroidal thickness in the RA group compared with the control group. There were no …

Evaluation Of Manual Keratoscope-Assisted Implantation Of Intrastromal Cornealring Segments In Patients With Keratoconus, Hany A. Khairy, Hend G. A. Ghonemy, Marwa A. Zaky, Mohamed S. Abdelaziz

Menoufia Medical Journal

Objective To evaluate the use of manual keratoscope intraoperative to improve the outcome of intracorneal ring segment (ICRS) implantation in patients with keratoconus. Background Keratoconus is a bilateral, progressive, noninflammatory disease of the cornea that often leads to high myopia and astigmatism. It seems to be a multifactorial disease with an unknown exact etiology that impairs the quantity and quality of vision secondary to thinning in and protrusion of the cornea. This results in irregular astigmatism with or without myopia. Methods This was a randomized prospective cohort, interventional case series study conducted at Tiba Ophthalmic Center, Menoufia during the period …

Comparative Study Of Refractive Outcomes After Photorefractive Keratectomy And Small-Incision Lenticule Extraction In Moderate Myopia, Abdelrahman Elsebaey, Ahmed I. Basiony, Khaled Elghonemy, Shaimaa M. Azzam

Menoufia Medical Journal

Objectives To compare the refractive outcomes after photorefractive keratectomy (PRK) and small-incision lenticule extraction (SMILE) in moderate myopia. Background PRK and SMILE are two flapless procedures for the correction of myopia and astigmatism. In PRK, an excimer laser is used for photoablation, whereas in SMILE, a femtosecond laser is used to create the lenticule. Patients and methods A retrospective study was conducted on 80 patients (160 eyes) who were classified into two groups: PRK and SMILE. A total of 40 patients (80 eyes) were included in each group. Assessment was between 6 months and 3 years postoperatively comparing the uncorrected …

Effect Of Vitamin D On The Efficacy Of Topical Artificial Tears In Patients With Dry-Eye Disease, A M. S. Fayed, Dina G. H. Abd Elmonem, Hatem M. Marey, Marwa A. Zaky

Menoufia Medical Journal

Background The tear film is a complex mix of electrolytes, proteins (lipocalins, lactoferrin, transferrin, defensin, and lysozyme), phospholipids, oligopeptides, glycopeptides, and immunoglobulins. Objective The aim was to investigate the efficacy of topical carbomer-based lipid-containing artificial tears and hyaluronate in patients with dry-eye disease (DED) based on serum 25-hydroxy vitamin D (25HD) levels and cholecalciferol (vitamin D) supplementation. Patients and methods A nonrandomized clinical trial study was conducted on 42 patients with DED by Schirmer tear-secretion test (mm) who were examined by Ophthalmology Department, Menoufia University Hospital, Egypt, during the study period from March 2020 to March 2021. Results Serum 25HD …

Changes In The Anterior Segment After Cataract Surgery And Intraocular Lens Implantation Using Ultrasonic Biomicroscopy, Hoda M. K. El-Sobky, Marwa A. Zaky, Mohamed F. H. Ibrahim

Menoufia Medical Journal

Objective To study changes in the anterior segment after cataract surgery and intraocular lens implantation by means of ultrasonic biomicroscopy. Background Cataract surgery is the only treatment for cataract with high success rate in restoring sight. Ultrasonic biomicroscopy is a noninvasive modality that allows for the real-time visualization of anterior-segment tissues with microscopic resolution and provides information about the size and the nature of the lesion, permitting a presumptive diagnosis. Patients and methods A prospective nonrandomized and comparative study was conducted on 20 eyes of 20 patients aged 43–72 years who attended the outpatient clinic of Menoufia University Hospital and …

Intravitreal Injection Of Ranibizumab For Treatment Of Macular Edema Secondary To Retinal Vein Occlusion, Asmaa M. Ibrahim, Hatem M. G. Marey, Manal M Salah El Deena

Menoufia Medical Journal

Objective This study aims to evaluate the effect of ranibizumab for treatment of macular edema (ME) secondary to retinal vein occlusion (RVO). Patients and methods This is a prospective case series study that included 35 eyes of patients with ME due to RVOs. This study was conducted in Menoufia University Hospital during the period study from March 2018 till February 2020. The study protocol was approved by the medical research ethics committee of Faculty of Medicine, Menoufia University. Results There was a significant improvement in the best-corrected visual acuity (VA) value in the fourth month postoperatively than preoperatively, whereas there …

Visual Outcome After Femtolasik Vs. Icl For Correction Of High Myopia, Abdelrahman E. Sarhan, Amin F. Ellakwa, Islam A. Sallam

Menoufia Medical Journal

Objectives To compare visual outcomes between femtosecond Lasik and implantable collamer lens (ICL) in patients with high myopia. Background Even though the parameters for optical quality as well as intraocular scattering are valuable for the subsequent satisfaction and postoperative visual performance in myopia, the comparison between patients with Femtolasik (FS-Lasik) and ICL implantation of these parameters is still unclear. Materials and methods This study involved 50 high myopic eyes ≥−6.0 D recruited for FS-Lasik (group 1) and another 50 high myopic eyes recruited for ICL (group 2). Both age and sex were matched in the two groups. Results Visual acuities …

Correlation Of Anterior Ocular-Segment Biometry With Glycated Hemoglobin Level In Type-2 Diabetic Patients, Gehan A. A. Elsabrout, Hatem M. G. Marey, Marwa A. Zaky

Menoufia Medical Journal

Background Diabetic retinopathy (DR), nephropathy, and peripheral neuropathy are the common complications of diabetes mellitus. DR is one of the causes of blindness worldwide. Although diabetic-eye disease is often thought to refer merely to the retina, the anterior segment of the eye has also been shown to be affected in diabetes. Objective To compare the anterior ocular-segment biometry among type-2 diabetes mellitus with no DR, nonproliferative diabetic retinopathy (NPDR), and evaluate the correlation of anterior ocular-segment biometry with glycosylated hemoglobin (HbA1c) level. Patients and methods A cross-sectional study was conducted on 48 patients. The patients were randomly selected from the …

Outcomes Of Bicanalicular Self-Retaining Stent Versus 3-Snip Punctoplasty In Management Of Punctal Stenosis, Ahmed S. Fayed, Hatem M. Marey, Jihad R. Ammar, Sameh S. Mandour

Menoufia Medical Journal

Objectives To evaluate and compare the outcomes of bicanalicular self-retaining stent (SRS) versus rectangular 3-snip punctoplasty in the treatment of acquired lower punctal stenosis. Background Punctal stenosis is a common disorder and one of the most commonly encountered diseases that cause tearing. Visual disturbance occurs because of constant epiphora. Patients and methods This prospective randomized comparative study was carried on 65 eyes of 39 patients with acquired lower punctal stenosis. Patients were categorized into two groups based on the intervention, such as insertion of bicanalicular SRS (group A) and rectangular 3-snip punctoplasty (group B). Assessment of epiphora, punctal stenosis grading, …

Surgically Induced Astigmatism Following Femtosecond Laser-Assisted Cataract Surgery Compared With Conventional Phacoemulsification, Abdel R. Sarhan, Hassan M. S. H. Sorour, Khaled El-Ghonemy, Sameh El-Gouhary

Menoufia Medical Journal

Objective In the present study, we reviewed surgically induced astigmatism (SIA) in femtosecond laser-assisted cataract surgery (FLACS) compared with conventional phacoemulsification in patients who have cataract. Background To assess SIA following clear corneal incisions created manually or with the Catalys femtosecond laser. Patients and methods In the present study, patients undergoing FLACS or manual cataract surgery between 2017 and 2019 from a single surgical center in Egypt were considered for inclusion. Postoperative corneal astigmatism values were compared with preoperative astigmatism indices to determine the SIA at 3 months postoperatively using the Alpins vector method. Results Refractive and topographic outcomes from …

Macular Thickness Assessment In Diabetic Patients Without Retinopathy, Adel G. Zaky, Amin F. Ellakwa, Asmaa A. Askria, Moatz F. Elsawy, Saber H. El Sayed

Menoufia Medical Journal

Objective A comparative study of macular thickness measurements with optical coherence tomography (OCT) in patients with diabetes mellitus without diabetic retinopathy (DR) versus healthy controls. Background DR is one of the most common causes of deterioration of vision in the adult population. Recently, some studies showed that the degeneration of the retinal neuronal cells starts before the microvascular changes appear clinically. Patients and methods Sixty-five patients with diabetes mellitus (without DR underwent full ophthalmic examination; colored fundus photography, fluorescin fundus angiography, and OCT. Mean macular thickness measured by OCT was calculated for the central fovea, the perifoveal, and the parafoveal …

Prevalence And Topographical Characteristics Of Keratoconus As A Type Of Corneal Ectasia Among Adult Egyptians With Refractive Errors, Amira A. Elsuofy, Farid Wagdy, Zeinab A. Kasemy

Menoufia Medical Journal

Objectives To determine the prevalence of keratoconus (KC) among Egyptian adult population. Background Corneal ectasia is a noninflammatory, bilateral, asymmetrical condition, causing progressive corneal steepening and thinning. KC is the most prevalent form of corneal ectasia and affects all ethnicities. Patients and methods A cross-sectional study was conducted on 1607 adults at an Egyptian Governorate aged more than 18 years with high myopia of above − 6 D and high astigmatism above − 3 D old at some public and private ophthalmology centers, in Lower Egypt during the period from May 2020 till February 2021. Evaluation of corneal topography (Scheimpflug …