Digital Commons Network^™

Role Of Surgery In The Prognosis Of Pediatric Thalamic Tumors, Mohamed Khaled Eissa, Mohamed Elbeltagy, Hesham Abou-Rahma, Hazem Mohamed Negm, Ahmed Said Mansour, Yasser Bahgat Elsisi

Menoufia Medical Journal

Objective: This study aimed to present the authors' experience in managing 20 cases of pediatric thalamic brain tumors. Background: Thalamic tumors constitute a small percentage (approximately 0.84-5.2%) of all brain tumors and are even rarer in the pediatric population, accounting for about 2-5% of pediatric brain tumors. These tumors present a significant challenge to neurosurgeons due to their intricate location within the brain and their proximity to crucial structures, especially in children. The management of these tumors necessitates careful consideration and expertise due to the potential risks associated with their critical position. Patients and Methods: In this retrospective study, the …

Prevalence Of Skin Diseases Among Primary School Children In Benha City, Kalubia Governorate, Egypt, Safa Hamdy Alkalash, Mohammed Abdelwahed Gaber, Ahmed Anwar Kamal

Menoufia Medical Journal

Objectives:To assess prevalence and types of skin diseases among primary school children in Benha city, Kalubia governorate, Egypt.

Background:Skin diseases are common among school-aged children,and many of such diseases are distressing for children in this age group.

Methods:An analytical cross-sectional study was performed on 400 children of primary school children from both sexes in Benhacity, Kalubia Governorate, Egypt,in a period from April 2019 to February 2022. A well-designed interviewer basedquestionnaire was applied to collect their demographic data, and medical history while signs of any skin disease were checked by the researcher through using a checklist.

Results: Mean age of the …

Prevalence Of Metabolic Syndrome In School-Aged Obese Children, Maha A. Tawfik, Mohamed A Abdo Al-Fiqi, Soheir S. Abou El-Ella, Zeinab S. Abou Zouna

Menoufia Medical Journal

Objective To evaluate the prevalence of metabolic syndrome (MS) in a group of school-aged obese children of both sexes. Background Data about MS in children are limited in Egypt as the prevalence and magnitude of obesity among school-aged children has been increasing dramatically. We examined the effect of varying degrees of obesity on the prevalence of the MS. Patients and methods This cross-sectional study was conducted on obese children (BMI ≥ 95^th percentile), aged 6–16 years. Detailed history taking with family pedigree; complete systemic examination; anthropometric measurements, including weight (kg) on Z score, height (m) on Z score, waist …

Neuroglobin As A Novel Biomarker In Childhood Seizures, Heba B. Abd Elsalam, Sameh A. Abd Elnaby, Sara M. Eldeeb, Yasmeen K E. El-Fiky

Menoufia Medical Journal

Objectives The aim of this study is to investigate the possible role of neuroglobin as a novel biomarker in children with febrile seizures and epileptic children. Background Neuroglobin is a new globin member that is highly expressed in the central and peripheral nervous system. Patients and methods This case–control study has been conducted on 75 children, divided into three groups: group I included children with simple febrile convulsions, group II included children with newly diagnosed idiopathic epilepsy, and group III included healthy children selected as controls. Serum neuroglobin assay, complete blood count, C-reactive protein level, random blood sugar, serum electrolytes, …

Clinical Assessment And Follow-Up Of School-Aged Diabetic Children, Kamel Gomaa, Maha A. Tawfik, Soheir S. A. El-Ella, Zeinab S. Abouzouna

Menoufia Medical Journal

Objective Clinical assessment and follow-up in school-aged diabetic children. Background Diabetes mellitus requires continuous medical care, patient self-management, education, and support to prevent acute complications and to reduce long-term complications. Patients and methods This descriptive study was conducted on 110 diabetic Egyptian children. All patients were subjected to detailed history taking, complete general examination including anthropometric measurements and laboratory investigations including estimation of fasting blood glucose level (mg/dl), postprandial blood glucose level (mg/dl), glycosylated hemoglobin (HbA1c%), lipid profile (cholesterol, low-density lipoprotein, and triglyceride), microalbumin in urine, and thyroid function (thyroid-stimulating hormone and FT4). Results The mean age of the studied …

A Clinical And Biochemical Study For Periostin In Atopic Dermatitis, Eman A. E. Badr, Hasnaa Mohamed Nasef, Hesham Nabil Khaled, Wafaa Ahmed Shehata

Menoufia Medical Journal

Objective This work was designed to study the role of periostin in children with atopic dermatitis (AD) and to correlate its level with the severity and chronicity of AD. Background Periostin is a recent mediator in chronic states of allergic diseases and has significant roles in tissue remodeling in allergic inflammation. It has a unique function as an intrinsic mediator in amplifying and preserving allergic skin inflammation and might be a virtual molecule in the development and occurrence of chronicity. Patients and methods The current work examined 40 children with AD and 40 age- and sex-matched healthy controls. Patients underwent …

Association Of Cytotoxic T Lymphocyte 4 Gene With Auto-Antibodies In Children With Type 1 Diabetes, Gamila S. Abdel Moaty, Maha A. Tawfik, Naglaa F. Barseem, Neama H. Zeariban, Soheir S. Abou El-Ella

Menoufia Medical Journal

Objective The aim of the study was to detect the association of CTLA4 gene with anti-insulin antibodies in type 1 diabetes in children. Background The objective was to evaluate the diagnostic workup done for diabetic children in its relation to clinical findings and diabetic control, and to study association of CTLA4 gene and anti-insulin antibodies in type 1 diabetes in children. Materials and methods The results showed no significant difference between male and females regarding serum anti-insulin antibodies and CTLA4 gene. There was a significant positive correlation between serum anti-insulin antibody and duration of disease of type 1 diabetes, but …

Serum Selenium Level In Children With Febrile Seizures, Ahmed T. Mahmoud, Hend M. E. K. Terad, Maha A. El Bassuoni, Sameh A. Abd El Naby

Menoufia Medical Journal

Objective The aim of the study is to assess serum level of selenium in children with febrile seizures (FSs) in relation to clinical findings. Background FSs are the most common form of childhood seizures. The exact etiopathogenesis is unknown. There were various hypotheses about the role of selenium deficiency in FSs. Patients and methods This case–control study involved 80 Egyptian children (6 months to 5 years), divided into four groups: group A included 20 children with FSs, group B included 20 children with afebrile seizures, group C included 20 children with fever without seizures, and group D included 20 healthy …

Pediatric Respiratory Assessment Measure In Evaluation Of The Severity Of Bronchial Asthma Exacerbation In Children, Amr M. Elewa, Ghada M. El Mashad

Menoufia Medical Journal

Objective The aim was to study the role of pediatric respiratory assessment measure (PRAM) score in evaluation of acute asthma exacerbation in children. Background Acute severe asthma is one of the most common medical emergency situations in childhood, where accurate assessment and management is of extreme importance and may be lifesaving. PRAM score has been used to classify asthma severity and treatment. Patients and methods A prospective cohort study was adopted by applying the PRAM score on 108 asthmatic children presented to the Emergency Department of Elraml Pediatric Hospital in Alexandria by acute asthma exacerbation in the period of the …

Association Between Thyroid Function And Lipid Profile Parameters Among Obese Children And Adolescents, Maha A. Tawfik, Marwa M. Mohasseb, Naglaa F. Barseem, Reem M. F. Shalaby

Menoufia Medical Journal

Objectives In this study, we evaluated free thyroxine and thyroid-stimulating hormone (TSH) concentrations between normal children and those with obesity and possible correlations between BMI and these markers. Background Evaluation of thyroid function determines the cause of obesity in children and adolescents. In children with obesity, TSH and thyroid hormone concentrations are shown to be high, which is accompanied by weight gain, increased cholesterol levels, and impaired growth velocity. Patients and methods This study was done on 200 Egyptian children and adolescents in the age of 5–18 years, comprising 71 overweight, 29 obese children and adolescents, and 100 nonobese children …

Role Of Urine Reagent Strips In Diagnosis Of Childhood Meningitis, Ahmed T. Mahmoud, Mohammad A. Elhag, Nahla M. Said, Reem M. El Kholy

Menoufia Medical Journal

Objective The aim was to evaluate the role of urine reagent strips in the diagnosis of childhood meningitis and differentiating between septic and aseptic types. Background Previous research studies have declared that clinical manifestations of acute bacterial meningitis can be very subtle, nonspecific, or even absent, especially in neonates and infants. Urine reagent strips have been used to test urine, ascetic fluid, and pleural aspirate to evaluate infection in these biologic fluids. Patients and methods To reach the goal of this research, a prospective study was designed. The study sample included 50 participants divided into two groups. The first group …

Intussusception In Children: Effect Of Symptom Duration On The Outcome Of Hydrostatic Reduction, Chukwubuike K. Emeka

Menoufia Medical Journal

Background Intussusception is a common cause of intestinal obstruction in children, especially in infants. Intussusception is a pediatric abdominal surgical emergency, and hydrostatic reduction is an effective modality of treatment in selected group of patients. There are lack of data in Nigeria on the effect of symptom duration on hydrostatic reduction. Aim To evaluate the effect of duration of symptoms on the outcome of hydrostatic reduction of intussusception. Patients and methods This was a prospective study on the effect of symptom duration on the success of hydrostatic reduction of intussusception in children. This study was carried out at the pediatric …

Nasal Foreign Bodies In Children – Our Experiences At A Tertiary Care Teaching Hospital In Eastern India, Jasashree Choudhury, Santosh K. Swain

Menoufia Medical Journal

Background Children with nasal foreign body (FB) often come to clinician for its removal. These children often present with foul-smelling nasal discharge, nasal obstruction, nasal mucosal irritation, and epistaxis. In most cases, unilateral nasal FB is easily removed but occasionally may lead to life-threatening situation. Objectives To study the details of the nasal FBs including treatment in children at a tertiary care teaching hospital of Eastern India. Patients and methods This retrospective study was done between June 2015 and July 2020 and included children attending the otorhinolaryngology clinic and emergency unit for nasal FB. Patient details such as age, sex, …

Topical Timolol Versus Oral Propranolol For The Treatment Of Hemangioma In Children, Saad M. Abd Elnaby, Tamer A. Sultan, Tamer F. Abd Elaziz

Menoufia Medical Journal

Objective To evaluate the clinical efficacy and adverse effects of oral propranolol in comparison with topical timolol for the treatment of hemangioma. Background Previous research declares that hemangioma is the most common tumor of infancy and childhood, occurring in 4–10% of white infants. Patients and methods To reach the goal of this research, a prospective randomized study was performed by selecting 20 patients with hemangioma attending the Pediatric Surgery Clinic at Menoufia Main University Hospital and Damanhur National Medical Institute. All patients were subjected to detailed history taking, clinical examination, echocardiogram, complete blood picture, liver and kidney functions, and blood …

Value Of Plasma Levels Of Cardiac Myosin-Binding Protein C As A Diagnostic And Prognostic Biomarker In Heart Failure, Ahmed A. Khatab, Basim A. El-Gazzar, Mohamed S. Rizk, Mohamed G. F Abdel Ghani

Menoufia Medical Journal

Objective To study the value of measuring plasma levels of cardiac myosin-binding protein C (cMyBP-C) as a biomarker in the diagnosis and prognosis of heart failure (HF) in pediatric patients. Background Previous research studies have declared that cMyBP-C phosphorylation modulates cardiac contractility. It is a thick filament-associated protein which regulates actin–myosin interaction and thereby the systolic and diastolic function of the heart and regulates cardiac contractility. CMyBP-C has been reported in many studies as a specific early diagnostic biomarker of myocardial infarction. Patients and methods To reach the goal of this research, a case–control study was designed. The study sample …

Recurrent Attacks Of Rheumatic Fever Among School-Age Children (6–12 Years), Dina E. A. Saleh, Hala M. El-Moselhy Shaheen, Noura A. Khalel, Seham M. Rgab

Menoufia Medical Journal

Objective To assess factors related to recurrence of rheumatic fever attacks among school-age children (6–12 years) in El-Mahala El-Kobra City, Gharbiya Governorate. Background Recurrent episodes of acute rheumatic fever (ARF) can lead to rheumatic heart disease with considerable morbidity and mortality in children. Patients and methods A cross-sectional study was conducted in a center for follow-up of patients with rheumatic fever and rheumatic heart diseases in El-Mahala El-Kobra City, Gharbiya Governorate. There were 237 cases aged 6–12 years attending the selected center during the years of the study (first of November 2015 to end of October 2017). All cases that …

Hyponatremia In Hospitalized Children With Bronchiolitis And Severe Bronchial Asthma, Maha A. Tawfiq, Manal A. Elsayed Yousef, Mohamed Mekawy, Soheir S. A. Elella

Menoufia Medical Journal

Objective The main objective is to study the frequency of hyponatremia in hospitalized children with bronchiolitis and severe bronchial asthma and its relation to severity of the disease. Background Hyponatremia is the most common electrolyte abnormality seen in hospitalized patients with lower respiratory tract infections such as bronchiolitis and bronchial asthma. Patients and methods This is a case–control study, involving 69 cases of bronchiolitis and 31 cases of severe bronchial asthma, conducted in Menoufia University Hospitals from November 2017 to April 2018. All cases were subjected to history taking, clinical assessment, and investigations, including complete blood count, C-reactive protein, serum …

Identification Of Risk Factors Of Attention-Deficit Hyperactivity Disorder In Egyptian Children, Fahima M. Hassaan, Mohammed E. A Abd Elhady, Rasha I. M. Noreldin, Sameh A. A Abd Elnaby, Wafaa M. M Abo El-Fotoh

Menoufia Medical Journal

Objective The aim was to identify the risk factors of attention-deficit hyperactivity disorder (ADHD) in Egyptian children. Background ADHD is the most commonly diagnosed neurodevelopmental disorder that begins during early childhood. Various psychological, social, genetic, and biochemical factors are thought to be involved in the etiopathogenesis of ADHD. Participants and methods A prospective, randomized comparative study was conducted on 50 children with the diagnosis of ADHD and 35 healthy children as the control group. All patients were selected from those attending the outpatient neurology clinic and those admitted in the Pediatric Department Menoufia University Hospital in the period from October …

Topographic Corneal Changes In Children With Vernal Keratoconjunctivitis, Adel G. Zaky, Hoda M. K. El-Sobky, Nagwan A. Gad

Menoufia Medical Journal

Objectives To determine corneal topographic characteristics of children with vernal keratoconjunctivitis (VKC) and compare the corneal topographic indices between patients with VKC and normal participants. Background Keratoconus is the most common corneal ectatic disorder, the cause of which is largely unknown. Many factors have been implicated, and ocular allergy is one of them. Patients and methods A cross-sectional prospective study was conducted on children with VKC who attended outpatient clinic of Menoufia University Hospital, Faculty of Medicine, Menoufia University, in the period from February 2018 to February 2019. All study patients were divided in two groups: group I included 50 …

Laparoscopic Inguinal Hernia Repair In Girls Using The Percutaneous Internal Ring Suturing Technique – Our Own Experience, Aditya P. Singh, Arun K. Gupta, Ramesh Tanger, Vinay Mathur

Menoufia Medical Journal

Objective We evaluate d the usefulness of the percutaneous internal ring suturing (PIRS) technique in girls only. Background PIRS is a percutaneous closure of the internal inguinal ring under the control of a telescope/laparoscope placed through the umbilicus. Material and methods Thirty girls underwent surgery using this method in our institution between 2016 and 2017. We used telescope (3 mm, 0°), spinal needle (20 G), and nonabsorbable polypropylene 3-0 suture. The insufflation pressure in the peritoneal cavity was maintained at 8–10 mmHg. Results We selected the isolated cases of the inguinal hernia in only girls. There was no need of …

Assessment Of Blood Level Of Vitamin C In Children With Bronchial Asthma, Ahmed A. Khatab, Fahima M. Hassan, Heba G. A El-Hameed, Rania S. El-Zayat, Sally M. El-Hefnawy

Menoufia Medical Journal

Objective The aim was to assess the serum level of vitamin C in children with bronchial asthma. Background Vitamin C is abundant in the extracellular and intracellular lining fluid of the lungs, so it can participate in the primary lung defense against the reduction of oxidative mechanisms and therefore it has protective effects against bronchial asthma. Patients and methods This study was a case–control study that involved 60 pediatric patients with bronchial asthma as the cases group and 25 apparently normal children as the control group. All patients and controls were subjected to the same history taking, clinical examination, and …

Parents' Perception Towards The Effect Of Mobile And Internet Use On Their Children's Health, Ahmed A. Mashal, Ali M. Elshafie, Nagwa N. Hegazy, Yousra A. Alghalban

Menoufia Medical Journal

Objective The aim of this study was to identify parents' perception towards the effect of internet use on their children health. Background The consequences of using internet sources at a young age are currently being studied comprehensively across the different parts of the world, as surfing the web had been found to have its pros and cons. It gives users independence, provides opportunities for global learning, and creates a platform for initiating social change. In contrast, it increase the likelihood of engaging in high risk and socially destructive behaviors. Parents recognize the significance of adopting technology in order to function …

Laryngeal Tuberculosis: A Rare Presentation In A Nigerian Child With Disseminated Tuberculosis, Abdulwasiu G. Omotosho, Damilola M. Oladele, Mohammed B. Abdulkadir, Rasheedat M. Ibraheem, Salihu S. Mohammed, Wahab B. R. Johnson

Menoufia Medical Journal

Tuberculosis (TB) remains a ravaging disease, particularly in the low-income countries, with a protean manifestation in children. Thus, a high index of suspicion is the key to clinching the diagnosis when presentation is in a rare form such as laryngeal TB. In this study, the case report of a 10-year-old female child with laryngeal TB in the setting of other typical clinical presentation associated with TB is highlighted.

Closed Reduction And Percutaneous Pinning For The Treatment Of Lateral Humeral Condyle Fracture, Ahmed M. Mabrouk, Hassan A. Neena, Mohammed E. Habib

Menoufia Medical Journal

Objective The aim of the present study was to evaluate the result of treatment of recent fracture of the lateral humeral condyle in children using closed reduction and percutaneous pinning. Background Few reports have focused on closed reduction and internal fixation of fractures of the lateral humeral condyle in children. We prospectively studied closed reduction and internal fixation to determine its usefulness as the treatment for fractures of the lateral condyle of the humerus in children. Patients and methods The lateral condylar humeral fractures were classified into three groups according to the degree of displacement and the fracture pattern as …

Effect Of Omega-3 On Tumor Necrosis Factor-Α In Children On Hemodialysis, Belal F. Montaser, Eman H. Dawood, Ghada M. El-Mashad, Sayed I. El Gebaly

Menoufia Medical Journal

Objectives The aim of this study was to assess the effect of high-dose omega-3 supplementation on tumor necrosis factor-α (TNF-α) in children on long-term hemodialysis. Background Patients who are on hemodialysis have elevated serum levels of inflammatory markers. Giving high doses of omega-3 supplementation results in significant decrease in TNF-α (one of the inflammatory markers). Patients and methods This study was conducted at a pediatric dialysis unit in Menoufia University hospital, and included 26 patients from January 2015 to April 2015. The study commenced after approval of the local institutional ethical committee of Menoufia University hospital and obtaining written consents …

Effect Of High-Dose Omega-3 On Inflammatory Markers In Children On Long-Term Hemodialysis, Alaa M. Mohamed K Bassiouny, Ali M. Elshafie, Belal A. Montser, Zein A. Omar

Menoufia Medical Journal

Objective The aim of this study was to evaluate the effect of high-dose omega-3 on inflammatory markers in children on long-term hemodialysis. Background Children with end-stage renal disease (ESRD) on hemodialysis have elevated serum levels of inflammatory markers. Prevention and treatment of inflammatory syndrome is of high priority in patients who are on hemodialysis. Omega-3 fatty acids have been postulated to reduce inflammatory markers. Patients and methods This prospective study included 26 children with ESRD on long-term hemodialysis in the Pediatric Hemodialysis Unit at Menoufia University Hospital who received 2 g omega-3 per day orally for 3 months, and inflammatory …

Surgical Aspects Of Common Acute Abdominal Problems In Infants And Children, Eslam M. Abd El-Hafez, Tamer A. Sultan, Tamer F. Abd El-Aziz

Menoufia Medical Journal

Objective The aim of this study was to discuss and evaluate the best diagnostic tool (clinical, radiological, laboratory, or endoscopy) used to reach a final diagnosis and best intervention for most common presentation of surgical causes of common acute abdominal problems in infants and children. Background Acute abdominal pain is a group of acute life-threatening condition that requires emergency hospital admission and often emergency surgical intervention within 24 h of duration. Patients and methods Hundred children of both sexes aged between 1 day and 12 years who presented with surgical causes of common acute abdominal problems were divided into two …

Seroprevalence Of Helicobacter Pylori Infection Among School Children In Al Qulubia Governorate, Dalia H. Abou-Elela, Marwa M. Hessen, Mohsen M. Deeb, Wael A. Bahbah, Mahmood D. Al-Mendalawi

Menoufia Medical Journal

Objective

The aim of this study was to determine the seroprevalence of Helicobacter pylori infection among apparently healthy Egyptian school children. Background

H. pylori infection has a widespread distribution, but the prevalence varies between developed and developing countries. Patients and Methods

A series of 400 apparently healthy children attending basic schools were included in our study. Serum samples were withdrawn and assayed for the presence of anti-H. pylori antibody (immunoglobulin G) measured by the enzyme-linked immunosorbent assay test, and studied for the effect of age, sex, and socioeconomic background. The children’s ages ranged from 6 to 13 years. All infected …

Hemoglobin A1c Level In Nondiabetic Children With End-Stage Renal Disease Receiving Regular Hemodialysis, El-Sayed I. El-Gebally, Ghada M. El-Mashad, Hend G. Talha, Maha M. Allam

Menoufia Medical Journal

Objective This study was designed to assess hemoglobin A1c (HbA1c) levels in nondiabetic children with end-stage renal disease (ESRD) receiving regular hemodialysis (HD). Background HbA1c level represents an established tool to monitor glycemic control in diabetic patients. Patients and methods We enrolled 30 nondiabetic ESRD children receiving HD as a HD group and 30 healthy children as a control group for this study. All children were subjected to full history taking and physical examination. HbA1c, fasting blood glucose, hemoglobin level, hematocrit value, serum calcium, potassium, phosphate, blood urea nitrogen, creatinine, and parathormone hormone were measured in all participants. HbA1c level …

Association Of Macrophage Migration Inhibitory Factor - 173 G/C Polymorphism With Dilated Cardiomyopathy In Children, Hanan Abd El-Aziz Mohamed El-Bagoury, Rania S. El-Zayat, Rasha I. N. El-Din, Rawhia H. El-Edel

Menoufia Medical Journal

Objective The objective of this study was to detect the relation between macrophage migration inhibitory factor (MIF) −173 G/C gene polymorphism and dilated cardiomyopathy (DCM) in children. Background DCM is the most common cardiomyopathy. Myocardial inflammation is one of the commonest mechanisms in cardiomyopathy. MIF plays an important role in the control of innate immune responses and promotes proinflammatory biological activities; hence, MIF gene polymorphisms may predispose affected hosts to severe inflammatory or infectious disease. Patients and methods This study was conducted on 50 patients, 30 patients with DCM and 20 age-matched and sex-matched healthy controls. All patients were subjected …