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Impact Of Southeast Asian Smoke On Aerosol Properties In Southwest China: First Comparison Of Model Simulations With Satellite And Ground Observations, Jun Zhu, Xiangao Xia, Jun Wang, Jinqiang Zhang, Christine Wiedinmyer, Jenny A. Fisher, Christoph A. Keller
Impact Of Southeast Asian Smoke On Aerosol Properties In Southwest China: First Comparison Of Model Simulations With Satellite And Ground Observations, Jun Zhu, Xiangao Xia, Jun Wang, Jinqiang Zhang, Christine Wiedinmyer, Jenny A. Fisher, Christoph A. Keller
Faculty of Science, Medicine and Health - Papers: part A
Smoke aerosols have been observed in Southwest China as a result of long-range transport from surrounding areas in March and April. The processes driving this transport and the resultant impact on regional aerosol optical properties are studied here through a combined use of the Goddard Earth Observing System (GEOS)-Chem chemistry transport model in conjunction with satellite and the first-ever ground-based observations in the Southwest China. The potential biomass burning source regions as well as their respective contributions to aerosol loading in Southwest China are quantified. Compared to Sun photometer observations of aerosol optical depth (AOD) at 550nm at eight stations …
Hox Measurements In The Summertime Upper Troposphere Over Europe: A Comparison Of Observations To A Box Model And A 3-D Model, E Regelin, H Harder, M Martinez, D Kubistin, C Tatum Ernest, H Bozem, T Klippel, Z Hosaynali-Beygi, H Fischer, R Sander, P Jockel, R Konigstedt, J Lelieveld
Hox Measurements In The Summertime Upper Troposphere Over Europe: A Comparison Of Observations To A Box Model And A 3-D Model, E Regelin, H Harder, M Martinez, D Kubistin, C Tatum Ernest, H Bozem, T Klippel, Z Hosaynali-Beygi, H Fischer, R Sander, P Jockel, R Konigstedt, J Lelieveld
Faculty of Science, Medicine and Health - Papers: part A
In situ airborne measurements of OH and HO2 with the HORUS (HydrOxyl Radical measurement Unit based on fluorescence Spectroscopy) instrument were performed in the summertime upper troposphere across Europe during the HOOVER 2 (HOx OVer EuRope) campaign in July 2007. Complementary measurements of trace gas species and photolysis frequencies were conducted to obtain a broad data set, which has been used to quantify the significant HOx sources and sinks. In this study we compare the in situ measurement of OH and HO2 with simulated mixing ratios from the constrained box model CAABA/MECCA (Chemistry As A Box Model Application/Module Efficiently Calculating …
The Use Of Remote Sensing To Scale Up Measures Of Carbonate Production On Reef Systems: A Comparison Of Hydrochemical And Census-Based Estimation Methods, Sarah Hamylton, Jacob Silverman, Emily Shaw
The Use Of Remote Sensing To Scale Up Measures Of Carbonate Production On Reef Systems: A Comparison Of Hydrochemical And Census-Based Estimation Methods, Sarah Hamylton, Jacob Silverman, Emily Shaw
Faculty of Science, Medicine and Health - Papers: part A
The present study uses remote-sensing imagery to estimate carbonate production of the complete One Tree Island reef system, Great Barrier Reef, using hydrochemical (alkalinity reduction) and census-based (budgetary) methods. For five sites representing different benthic cover types across the reef system, carbonate production is determined using hydrochemical techniques that incubate substrates in a local aquarium and measure total alkalinity, total ammonia nitrogen, and total oxidized nitrogen. Local estimates are scaled up to the reef-system scale using a WorldView-2 satellite image, which is ground truthed against a field data set of 350 spatially referenced records of benthic assemblage. Annual total reef …
Paleoclimate Data-Model Comparison And The Role Of Climate Forcings Over The Past 1500 Years, Steven J. Phipps, Helen V. Mcgregor, Joelle Gergis, Ailie J. E Gallant, Raphael Neukom, Samantha Stevenson, Duncan Ackerley, Josephine R. Brown, Matt J. Fischer, Tas D. Van Ommen
Paleoclimate Data-Model Comparison And The Role Of Climate Forcings Over The Past 1500 Years, Steven J. Phipps, Helen V. Mcgregor, Joelle Gergis, Ailie J. E Gallant, Raphael Neukom, Samantha Stevenson, Duncan Ackerley, Josephine R. Brown, Matt J. Fischer, Tas D. Van Ommen
Faculty of Science, Medicine and Health - Papers: part A
The past 1500 years provide a valuable opportunity to study the response of the climate system to external forcings. However, the integration of paleoclimate proxies with climate modeling is critical to improving the understanding of climate dynamics. In this paper, a climate system model and proxy records are therefore used to study the role of natural and anthropogenic forcings in driving the global climate. The inverse and forward approaches to paleoclimate data–model comparison are applied, and sources of uncertainty are identified and discussed. In the first of two case studies, the climate model simulations are compared with multiproxy temperature reconstructions. …
A Comparison Of The Impact Of 'Seagrass-Friendly' Boat Mooring Systems On Posidonia Australis, Marie-Claire A. Demers, Andrew R. Davis, Nathan A. Knott
A Comparison Of The Impact Of 'Seagrass-Friendly' Boat Mooring Systems On Posidonia Australis, Marie-Claire A. Demers, Andrew R. Davis, Nathan A. Knott
Faculty of Science, Medicine and Health - Papers: part A
Permanent boat moorings have contributed to the decline of seagrasses worldwide, prompting the development of ‘seagrass-friendly’ moorings. We contrasted seagrass cover and density (predominantly Posidonia australis) in the vicinity of three mooring types and nearby reference areas lacking moorings in Jervis Bay, Australia. We examined two types of ‘seagrass-friendly’ mooring and a conventional ‘swing’ mooring. ‘Swing’ moorings produced significant seagrass scour, denuding patches of ∼9 m radius. Seagrass-friendly ‘cyclone’ moorings produced extensive denuded patches (average radius of ∼18 m). Seagrass-friendly ‘screw’ moorings, conversely, had similar seagrass cover to nearby reference areas. Our findings reinforce previous work highlighting the negative effects …
Reflection Impulsivity In Adolescent Cannabis Users: A Comparison With Alcohol-Using And Non-Substance-Using Adolescents, Nadia Solowij, Katy A. Jones, Megan E. Rozman, Sasha M. Davis, Joseph Ciarrochi, Patrick C. L Heaven, Nicole Pesa, Dan I. Lubman, Murat Yucel
Reflection Impulsivity In Adolescent Cannabis Users: A Comparison With Alcohol-Using And Non-Substance-Using Adolescents, Nadia Solowij, Katy A. Jones, Megan E. Rozman, Sasha M. Davis, Joseph Ciarrochi, Patrick C. L Heaven, Nicole Pesa, Dan I. Lubman, Murat Yucel
Faculty of Health and Behavioural Sciences - Papers (Archive)
Rationale Reflection impulsivity-a failure to gather and evaluate information before making a decision-is a critical component of risk-taking and substance use behaviours, which are highly prevalent during adolescence. Objectives and methods The Information Sampling Test was used to assess reflection impulsivity in 175 adolescents (mean age 18.3, range 16.5-20; 55% female)-48 cannabis users (2.3 years use, 10.8 days/month), 65 alcohol users, and 62 non-substance-using controls-recruited from a longitudinal cohort and from the general community and matched for education and IQ. Cannabis and alcohol users were matched on levels of alcohol consumption. Results Cannabis users sampled to the lowest degree of …
Comparison Of Assessment Performance Of Rural And Regional Students In A Unique Australian Graduate-Entry Medical Program, David L. Garne, J Bushnell, A Lethbridge, J Douglas
Comparison Of Assessment Performance Of Rural And Regional Students In A Unique Australian Graduate-Entry Medical Program, David L. Garne, J Bushnell, A Lethbridge, J Douglas
Faculty of Science, Medicine and Health - Papers: part A
The Graduate School of Medicine at the University of Wollongong is one of Australia's newest medical schools, with a regional/rural focus and a distributed campus, and students are all expected to spend a significant proportion of their training in a rural setting. Due to the diverse learning environments that students are exposed to, we sought to determine by phase if there was any difference in examination results between groups who were located in rural settings and those in regional settings.
Sciamachy Wfm-Doas Xco2: Comparison With Carbontracker Xco2 Focusing On Aerosols And Thin Clouds, J Heymann, O Schneising, Markus Reuter, M Buchwitz, V V. Rozanov, Voltaire A. Velazco, H Bovensmann, J P. Burrows
Sciamachy Wfm-Doas Xco2: Comparison With Carbontracker Xco2 Focusing On Aerosols And Thin Clouds, J Heymann, O Schneising, Markus Reuter, M Buchwitz, V V. Rozanov, Voltaire A. Velazco, H Bovensmann, J P. Burrows
Faculty of Science, Medicine and Health - Papers: part A
Carbon dioxide (CO2) is the most important greenhouse gas whose atmospheric loading has been significantly increased by anthropogenic activity leading to global warming. Accurate measurements and models are needed in order to reliably predict our future climate. This, however, has challenging requirements. Errors in measurements and models need to be identified and minimised. In this context, we present a comparison between satellite-derived column-averaged dry air mole fractions of CO2, denoted XCO2, retrieved from SCIAMACHY/ENVISAT using the WFM-DOAS (weighting function modified differential optical absorption spectroscopy) algorithm, and output from NOAA's global CO2 modelling and assimilation system CarbonTracker. We investigate to what …
A Comparison Of Treatment Outcomes For Individuals With Substance Use Disorder Alone And Individuals With Probable Dual Diagnosis, Elizabeth K. Cridland, Frank P. Deane, Ching-I Hsu, Peter J. Kelly
A Comparison Of Treatment Outcomes For Individuals With Substance Use Disorder Alone And Individuals With Probable Dual Diagnosis, Elizabeth K. Cridland, Frank P. Deane, Ching-I Hsu, Peter J. Kelly
Faculty of Health and Behavioural Sciences - Papers (Archive)
The co-occurrence of substance use and mental health problems, often referred to as dual diagnosis (DD), is increasingly recognised as commonplace within substance abuse treatment programs. Two-hundred and thirty-four individuals from 9 Australian Salvation Army drug and alcohol rehabilitation programs completed a 3-month post-discharge telephone follow-up. Using a cut-off score from the Psychiatric Subscale of the Addiction Severity Index (5th ed.), 66.7% were classified as likely to have DD and 33.3% as substance use disorder only (SUD). Both groups reported comparable and decreased substance use levels at follow-up, yet DD individuals perceived less improvement in substance use problems. Comparable improvements …
A Comparison Of The Effect Of Mobile Phone Use And Alcohol Consumption On Driving Simulation Performance, Sumie Leung, Rodney J. Croft, Melinda L. Jackson, Mark E. Howard, Raymond J. Mckenzie
A Comparison Of The Effect Of Mobile Phone Use And Alcohol Consumption On Driving Simulation Performance, Sumie Leung, Rodney J. Croft, Melinda L. Jackson, Mark E. Howard, Raymond J. Mckenzie
Faculty of Health and Behavioural Sciences - Papers (Archive)
Objective: The present study compared the effects of a variety of mobile phone usage conditions to different levels of alcohol intoxication on simulated driving performance and psychomotor vigilance. Methods: Twelve healthy volunteers participated in a crossover design in which each participant completed a simulated driving task on 2 days, separated by a 1-week washout period. On the mobile phone day, participants performed the simulated driving task under each of 4 conditions: no phone usage, a hands-free naturalistic conversation, a hands-free cognitively demanding conversation, and texting. On the alcohol day, participants performed the simulated driving task at four different blood alcohol …
Comparison Of The Dietadvice Website In The Clinical Trial And Primary Healthcare Contexts, Yasmine Probst, Kathryn Boyd, Virva Walkington, Linda C. Tapsell
Comparison Of The Dietadvice Website In The Clinical Trial And Primary Healthcare Contexts, Yasmine Probst, Kathryn Boyd, Virva Walkington, Linda C. Tapsell
Faculty of Health and Behavioural Sciences - Papers (Archive)
The aim of this study was to evaluate the use of the DietAdvice website, a self-administered online dietary assessment, in the context of a dietary intervention randomized controlled trial [ACTRN 12608000425392]. Data available from a total of n=118 volunteers recruited to the dietary trial and using the website in the clinic at t=0, 3 and 12mo was compared with that obtained from diet histories (DH) and 3-day food record (FR). Fasting blood samples from these time points were also correlated with the macronutrient values obtained. Complete web based records were obtained for 65% of participants at t=0, 83% at t=3 …
A Behavioural Comparison Of Acute And Chronic Δ9-Tetrahydrocannabinol And Cannabidiol In C57bl/6jarc Mice, Ian Mcgregor, Xu-Feng Huang, Tim Karl, Jonathon Arnold, Rose Chesworth, Leonora E. Long
A Behavioural Comparison Of Acute And Chronic Δ9-Tetrahydrocannabinol And Cannabidiol In C57bl/6jarc Mice, Ian Mcgregor, Xu-Feng Huang, Tim Karl, Jonathon Arnold, Rose Chesworth, Leonora E. Long
Faculty of Health and Behavioural Sciences - Papers (Archive)
Cannabis contains over 70 unique compounds and its abuse is linked to an increased risk of developing schizophrenia. The behavioural profiles of the psychotropic cannabis constituent Δ9-tetrahydrocannabinol (Δ9-THC) and the non-psychotomimetic constituent cannabidiol (CBD) were investigated with a battery of behavioural tests relevant to anxiety and positive, negative and cognitive symptoms of schizophrenia. Male adult C57BL/6JArc mice were given 21 daily intraperitoneal injections of vehicle, Δ9-THC (0.3, 1, 3 or 10 mg/kg) or CBD (1, 5, 10 or 50 mg/kg). Δ9-THC produced the classic cannabinoid CB1 receptor-mediated tetrad of hypolocomotion, analgesia, …
Comparison Of Multiple And Novel Measures Of Dietary Glycemic Carbohydrate With Insulin Resistant Status In Older Women, Therese O'Sullivan, Alexandra P. Bremner, Sheila O'Neill, Philippa M. Lyons-Wall
Comparison Of Multiple And Novel Measures Of Dietary Glycemic Carbohydrate With Insulin Resistant Status In Older Women, Therese O'Sullivan, Alexandra P. Bremner, Sheila O'Neill, Philippa M. Lyons-Wall
Faculty of Health and Behavioural Sciences - Papers (Archive)
Background: Previous epidemiological investigations of associations between dietary glycemic intake and insulin resistance have used average daily measures of glycemic index (GI) and glycemic load (GL). We explored multiple and novel measures of dietary glycemic intake to determine which was most predictive of an association with insulin resistance. Methods: Usual dietary intakes were assessed by diet history interview in women aged 42-81 years participating in the Longitudinal Assessment of Ageing in Women. Daily measures of dietary glycemic intake (n = 329) were carbohydrate, GI, GL, and GL per megacalorie (GL/Mcal), while meal based measures (n = 200) were breakfast, lunch …
Comparison Of Computerised Dietary Assessments With Diet History And Food Record Data At Baseline In An Australian Food-Based Clinical Trial, Yasmine Probst, Virva Sarmas, Linda C. Tapsell
Comparison Of Computerised Dietary Assessments With Diet History And Food Record Data At Baseline In An Australian Food-Based Clinical Trial, Yasmine Probst, Virva Sarmas, Linda C. Tapsell
Faculty of Health and Behavioural Sciences - Papers (Archive)
Background: Food-based clinical trials are vital to advance the scientific evidence for the impact of food on health. These trials reqUire stringent dietary assessment to substantiate effects. We are evaluating the use of a self-administered computerised dietary assessment (DietAdvice) in a current food based weight loss trial. Objective: This cross sectional study aims to compare data from DietAdvice with diet history (DH) and food record (FR) dietary assessments measured at baseline. Materials and Methods: Baseline data for n=71 overweight (23-60 years, BMI 25-37 kg/m2) participants was utilised. Macronutrient data for matched dietary assessments from n=32 participants was obtained for the …
A Comparison Of Two Nutrition Signposting Systems For Use In Australia, Jimmy Chun Yu Louie, Victoria M. Flood, Anna Rangan, Debra J. Hector, Tim Gill
A Comparison Of Two Nutrition Signposting Systems For Use In Australia, Jimmy Chun Yu Louie, Victoria M. Flood, Anna Rangan, Debra J. Hector, Tim Gill
Faculty of Health and Behavioural Sciences - Papers (Archive)
Consumers are interested in making healthier food choices but the mandatory nutrition information panel currently in use in Australia is not easily understood or interpreted by most consumers. A simple nutrition signpost would be valuable. This paper reviews two nutrition signposting systems currently being considered for adoption in Australia. The authors conclude that a system similar to the colour-coded Traffic Light System is likely to be most useful.
The Relevance Of The Heart Foundation Of Australia's Dietary Recommendations For Adult Australians: A Comparison Of Views Of General Practitioners, Cardiologists And Dietitians, Francis A. Worsley, Sylvia Pomeroy
The Relevance Of The Heart Foundation Of Australia's Dietary Recommendations For Adult Australians: A Comparison Of Views Of General Practitioners, Cardiologists And Dietitians, Francis A. Worsley, Sylvia Pomeroy
Faculty of Health and Behavioural Sciences - Papers (Archive)
Purpose: To compare the views of general practitioners, cardiologists and dietitians about the relevance of the Heart Foundation of Australias dietary recommendations for adult cardiac patients. Basic procedures: Quantitative-cross sectional study. Postal questionnaires were self-completed by 248 Victorian general practitioners (30% response), 189 Australia-wide cardiologists (47% response) and 180 Victorian dietitians (45% response). Responses were represented as percentages and analyses of variance were conducted to explore the impact of the independent variables: age, work status and gender on the dependent variable: dietary recommendation. Main findings: Approximately half of the recommendations were viewed as strongly important to implement; these related to …
Health Claims And Food Advertising: Comparison Of Marketing And Nutrition Experts' Ratings Of Magazine Advertisements, Sandra C. Jones, Peter Williams, Linda C. Tapsell, Kelly L. Andrews
Health Claims And Food Advertising: Comparison Of Marketing And Nutrition Experts' Ratings Of Magazine Advertisements, Sandra C. Jones, Peter Williams, Linda C. Tapsell, Kelly L. Andrews
Faculty of Health and Behavioural Sciences - Papers (Archive)
To determine the nature and differences in expert opinion from the fields of nutrition and marketing on the use of health claims in the 30 most frequently appearing Australian magazine food advertisements, a survey was conducted with 28 nutritionists and 21 marketing experts in Australia and New Zealand. The experts assessed the advertisements with respect to the accuracy of the nutrition claims, the tactics and intentions of the advertising strategy and the accessibility of the nutrition information to lay consumers. Of 28 advertisements where a claim was identified, for only one did more than 90% believe the claim to be …
Comparison Of The Effects Of Continuous And Pulsed Mobile Phone Like Rf Exposure On The Human Eeg, N Perentos, R J. Croft, R J. Mckenzie, D Cvetkovic, I Cosic
Comparison Of The Effects Of Continuous And Pulsed Mobile Phone Like Rf Exposure On The Human Eeg, N Perentos, R J. Croft, R J. Mckenzie, D Cvetkovic, I Cosic
Faculty of Health and Behavioural Sciences - Papers (Archive)
It is not clear yet whether Global System for Mobiles (GSM) mobile phone radiation has the ability to interfere with normal resting brain function. There have been reports that GSM exposure increases alpha band power, and does so only when the signal is modulated at low frequencies (Huber, R., Treyer, V., Borbely, A. A., Schuderer, J., Gottselig, J. M., Landolt, H.P., Werth, E., Berthold,T., Kuster, N., Buck, A and Achermann, P. Electromagnetic fields, such as those from mobile phones, alter regional cerebral blood flow and sleep and waking EEG. J Sleep Res 11, 289-295, 2002.) However, as that research employed …
A Cognitive-Behavioural Comparison Of Binge Eating And Non-Binge Eating In A Non-Clinical Population, Brianna K. Richards, Leanne E. Warner, Christen Elks, Craig J. Gonsalvez
A Cognitive-Behavioural Comparison Of Binge Eating And Non-Binge Eating In A Non-Clinical Population, Brianna K. Richards, Leanne E. Warner, Christen Elks, Craig J. Gonsalvez
Faculty of Health and Behavioural Sciences - Papers (Archive)
Binge eating episodes occur in a significant proportion of the non-clinical population, although only a small proportion of these individuals progress to developing disabling eating disorders. The purpose of this research was to examine the nature of binge eating episodes verses non-binge eating episodes and the nature of subjective binge eating episodes and objective binge eating episodes as they occur in a non-clinical population. This study consisted of 113 undergraduate psychology students who completed a range of self-report measures including the Eating Disorder Inventory-2 (EDI-2), demographics questionnaire and binge diary. Sixty-seven percent reported that they had experienced a binge-eating episode …
An Allometric Comparison Of Microsomal Membrane Lipid Composition And Sodium Pump Molecular Activity In The Brain Of Mammals And Birds, Anthony J. Hulbert, Paul Else, Nigel Turner
An Allometric Comparison Of Microsomal Membrane Lipid Composition And Sodium Pump Molecular Activity In The Brain Of Mammals And Birds, Anthony J. Hulbert, Paul Else, Nigel Turner
Faculty of Health and Behavioural Sciences - Papers (Archive)
Previous research has shown that the lipid milieu surrounding membrane proteins may be an important factor in determining their activity. To investigate this we have examined sodium pump molecular activity and microsomal membrane lipid composition in the brain of five mammalian and eight avian species ranging in size from 30 g mice to 280 kg cattle and 13 g zebra finches to 35 kg emus, respectively. Sodium pump (Na+,K+-ATPase) activity was higher in the smaller species and showed a significant allometric decline with body mass in both the mammals (μmol Pi h-1 mg wet …
Determining Rotational Temperatures From The Oh(8-3) Band, And A Comparison With (Oh96-2) Rotational Temperatures At Davis, Antarctica, Frances Phillips, G B. Burns, W J R French, P F B Williams, A R. Klekociuk, R P. Lowe
Determining Rotational Temperatures From The Oh(8-3) Band, And A Comparison With (Oh96-2) Rotational Temperatures At Davis, Antarctica, Frances Phillips, G B. Burns, W J R French, P F B Williams, A R. Klekociuk, R P. Lowe
Faculty of Science, Medicine and Health - Papers: part A
Rotational temperatures derived from the OH(8–3) band may vary by ~18K depending on the choice of transition probabilities. This is of concern when absolute temperatures or trends determined in combination with measurements of other hydroxyl bands are important. In this paper, measurements of the OH(8–3) temperature-insensitive Q/P and R/P line intensity ratios are used to select the most appropriate transition probabilities for use with this band. Aurora, airglow and solar and telluric absorption in the OH(8–3) band are also investigated. Water vapour absorption of P1(4), airglow or auroral contamination of P1(2) and solar absorption in the …
Mesospheric Temperatures From Observations Of The Hydroxyl (6-2) Emission Above Davis, Antarctica: A Comparison Of Rotational And Doppler Measurements, J L. Innis, Frances Phillips, G B. Burns, P A. Greet, W J R French, P L. Dyson
Mesospheric Temperatures From Observations Of The Hydroxyl (6-2) Emission Above Davis, Antarctica: A Comparison Of Rotational And Doppler Measurements, J L. Innis, Frances Phillips, G B. Burns, P A. Greet, W J R French, P L. Dyson
Faculty of Science, Medicine and Health - Papers: part A
We present observations of the hydroxyl (6–2) airglow lines from ~ 87 km altitude obtained at Davis station, Antarctica, in the austral winter of 1999. Nine nights of observations were made of the P-branch near λ840 nm with a Czerny-Turner scanning spectrometer (CTS); at the same time, high-resolution Fabry-Perot Spectrometer (FPS) spectra were collected of the Q1(1) doublet at λ834 nm. Rotational temperatures were determined from the CTS observations, while Doppler temperatures were derived from the line-widths of the FPS Q1(1) spectra. Absolute temperatures determined by these methods are uncertain by ~ 2 and ~ 20 …
Comparison Of Assays For Measuring Plasma Paracetamol. Possibility Of Calibration Error Needs Evaluation, Alison L. Jones, D R. Jarvie, D Simpson, L F. Prescott
Comparison Of Assays For Measuring Plasma Paracetamol. Possibility Of Calibration Error Needs Evaluation, Alison L. Jones, D R. Jarvie, D Simpson, L F. Prescott
Graduate School of Medicine - Papers (Archive)
Egleston et al report a significant difference in plasma paracetamol concen trations assayed with the AcetaSite bench assay and a standard laboratory assay. Rapid and accurate determinations of plasma paracetamol concentrations are crucial in the expeditious and appropriate administration of antidotal treatment, which prevents severe liver damage if given sufficiently early in the course of poisoning.
Evidence Of Multiple Mechanisms Of Avermectin Resistance In Haemonchus Contortus--Comparison Of Selection Protocols, Jennifer H. Gill, Caroline A. Kerr, Wesley L. Shoop, Ernest Lacey
Evidence Of Multiple Mechanisms Of Avermectin Resistance In Haemonchus Contortus--Comparison Of Selection Protocols, Jennifer H. Gill, Caroline A. Kerr, Wesley L. Shoop, Ernest Lacey
Graduate School of Medicine - Papers (Archive)
Three isolates of Haemonchus contortus selected for avermectin resistance in sheep were compared in three in vitro pharmacological tests previously shown to discriminate between field isolates of H. contortus resistant and susceptible to the avermectins. Two isolates, F7-A and IVC, were selected for avermectin resistance in the laboratory from a reference susceptible isolate using suboptimal doses of ivermectin (LD95) for 7 and 16 generations, respectively. In these isolates avermectin resistance was not associated with a decreased sensitivity to avermectin inhibition of larval development or L3 motility but was associated with an increased sensitivity to paraherquamide. The third isolate, Warren, was …