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A Covid-19 First Evaluation Clinic At A University Hospital In Turkey, Gülçi̇n Telli̇ Di̇zman, Gökhan Metan, Çağlayan Merve Ayaz Ceylan, Hayri̇ye Altunay, Mertcan Uzun, Gamze Gürsoy, Zahi̇t Taş, Gi̇zem Karahan, Fari̇da Ahmadova, Tuğba Saricaoğlu, Zeynep Cansu Çalişkan, Alpaslan Alp, Meli̇ha Çağla Sönmezer, Ahmet Çağkan İnkaya, Ahmet Görkem Er Jan 2022

A Covid-19 First Evaluation Clinic At A University Hospital In Turkey, Gülçi̇n Telli̇ Di̇zman, Gökhan Metan, Çağlayan Merve Ayaz Ceylan, Hayri̇ye Altunay, Mertcan Uzun, Gamze Gürsoy, Zahi̇t Taş, Gi̇zem Karahan, Fari̇da Ahmadova, Tuğba Saricaoğlu, Zeynep Cansu Çalişkan, Alpaslan Alp, Meli̇ha Çağla Sönmezer, Ahmet Çağkan İnkaya, Ahmet Görkem Er

Turkish Journal of Medical Sciences

Background/aim: We aimed to analyze the usefulness of such a reserved area for the admission of the patients' symptoms suggesting COVID-19 and compare the demographic and clinical characteristics of the patients with COVID-19 and without COVID-19 who were admitted to C1 during the first month of the COVID-19 outbreak in our hospital. Materials and methods: A new area was set up in Hacettepe University Adult Hospital to limit the contact of COVID-19 suspicious patients with other patients, which was named as COVID-19 First Evaluation Outpatient Clinic (C1). C1 had eight isolation rooms and two sampling rooms for SARS-CoV-2 polymerase-chain-reaction (PCR). …


Arthroscopic Bankart Repair Improves Upper Limb Exercise Capacity, Shoulder Function And Quality Of Life, Fi̇gen Dağ, Fehmi̇ Volkan Öztuna, Di̇dem Deri̇ci̇ Yildirim, Özlem Bölgen Çi̇men Jan 2022

Arthroscopic Bankart Repair Improves Upper Limb Exercise Capacity, Shoulder Function And Quality Of Life, Fi̇gen Dağ, Fehmi̇ Volkan Öztuna, Di̇dem Deri̇ci̇ Yildirim, Özlem Bölgen Çi̇men

Turkish Journal of Medical Sciences

No abstract provided.


Classical Heart Rate Variability And Non-Linear Heart Rate Analysis In Mice Under Na-Pentobarbital And Ketamine/Xylazine Anesthesia., Hasan Kazdağli, Hasan Fehmi̇ Özel, Mustafa Özbek, Şüheda Alpay, Mürüvvet Alenbey Jan 2022

Classical Heart Rate Variability And Non-Linear Heart Rate Analysis In Mice Under Na-Pentobarbital And Ketamine/Xylazine Anesthesia., Hasan Kazdağli, Hasan Fehmi̇ Özel, Mustafa Özbek, Şüheda Alpay, Mürüvvet Alenbey

Turkish Journal of Medical Sciences

No abstract provided.


Nucleolus Assessment In Invasive Breast Carcinoma, An Objective Parameter For Histological Grading, Seda Duman Öztürk, Çi̇ğdem Öztürk, Oğuzhan Okcu, Bayram Şen, Recep Bedi̇r Jan 2022

Nucleolus Assessment In Invasive Breast Carcinoma, An Objective Parameter For Histological Grading, Seda Duman Öztürk, Çi̇ğdem Öztürk, Oğuzhan Okcu, Bayram Şen, Recep Bedi̇r

Turkish Journal of Medical Sciences

Background/aim: The nucleolus has the potential to provide insight into how many types of cancer will progress. In this study, we examined the evaluation of the nucleolus with a microscope in widespread breast cancer tumors and whether this value contributes to tumor grading as an objective clinicopathological parameter. Materials and methods: In our study, the nucleolus was evaluated retrospectively in resections with a diagnosis of invasive breast carcinoma of the cases between January 2010 and April 2021. In total, the tumor nucleolus of 377 cases of invasive breast carcinoma was evaluated. Nucleolus evaluation was performed with light microscopy using four …


The Effect Of Immunonutrition On Tumor Infiltrative T Lymphocytes And Regulatory T Cells In Rectal Tumor Patients Receiving Neoadjuvant Chemoradiotherapy: A Prospective Randomized Clinical Study, Mehmet Onur Gül, Cebrai̇l Akyüz, Selvi̇naz Özkara Jan 2022

The Effect Of Immunonutrition On Tumor Infiltrative T Lymphocytes And Regulatory T Cells In Rectal Tumor Patients Receiving Neoadjuvant Chemoradiotherapy: A Prospective Randomized Clinical Study, Mehmet Onur Gül, Cebrai̇l Akyüz, Selvi̇naz Özkara

Turkish Journal of Medical Sciences

Background/aim: The rationale behind using immunonutrition in cancer patients is to prevent malnutrition, manage the host's immune response, and keep cancer under control by utilizing the potential immune system available in the host against the tumor. This prospective- study aims to assess the impact of immunonutrition on tumor-infiltrating lymphocytes (TILs) and regulatory T cells (Tregs) in rectal cancer patients receiving neoadjuvant chemoradiotherapy. Materials and methods: This is a single-center, prospective study. Forty patients diagnosed with middle and lower rectal tumors were enrolled in the study between March 2018 and December 2019. Nutrition protocols were given to all study subjects prior …


Factors Associated With Treatment Success After Combined Transforaminal Epidural Steroid Injection And Dorsal Root Ganglion Pulsed Radiofrequency Treatment In Patients With Chronic Lumbar Radicular Pain, Gülçi̇n Gazi̇oğlu Türkyilmaz Jan 2022

Factors Associated With Treatment Success After Combined Transforaminal Epidural Steroid Injection And Dorsal Root Ganglion Pulsed Radiofrequency Treatment In Patients With Chronic Lumbar Radicular Pain, Gülçi̇n Gazi̇oğlu Türkyilmaz

Turkish Journal of Medical Sciences

Background/aim: The aim of the study is to identify predictors of treatment success with combined transforaminal epidural steroid injection (TFESI) and dorsal root ganglion pulsed radiofrequency (DRG-PRF) in patients with lumbar radicular pain (LRP) associated with lumbar disc herniation. Materials and methods: The study included 48 patients with herniation-related LRP who underwent TFESI and DRG-PRF treatment between November 1, 2020 and April 30, 2021. Patient age, sex, symptom duration, history of lumbar surgery, and numeric rating scale (NRS) pain scores before and at 10 days, 1 month, and 3 months after treatment were evaluated retrospectively. Treatment success was defined as …


The Clinical, Pathological, And Genetic Characteristics Of Lipid Storage Myopathy In Northern China, Jingzhe Han, Shan Lu, Xueqin Song, Guang Ji, Yanan Xie, Hongran Wu Jan 2022

The Clinical, Pathological, And Genetic Characteristics Of Lipid Storage Myopathy In Northern China, Jingzhe Han, Shan Lu, Xueqin Song, Guang Ji, Yanan Xie, Hongran Wu

Turkish Journal of Medical Sciences

Background/aim: The lipid storage myopathy (LSM) diagnosis is based on the patient's clinical manifestations and muscle pathology. However, when genetic testing is lacking, there is a high rate of misdiagnosis of the disease. This study aimed to investigate the clinical and pathological features of genetically diagnosed LSM in northern China, analyze genetic mutations' characteristics, and improve the LSM diagnostic rate. Materials and methods: Twenty patients with LSM diagnosed were collected; meanwhile, the clinical data, muscle samples, and routine pathological staining of muscle specimens were collected. The morphological changes of muscle fibers were observed under an optical microscope. Results: Among the …


A Combination Of Q-Tof Lc/Ms And Lc-Ms/Ms Based Metabolomics In Pediatric-Onset Multiple Sclerosis Demonstrates Potential Biomarkers For Unclassified Patients, İsmai̇l Solmaz, Ozan Kaplan, Mustafa Çelebi̇er, İnci̇lay Lay, Fatma Banu Anlar Jan 2022

A Combination Of Q-Tof Lc/Ms And Lc-Ms/Ms Based Metabolomics In Pediatric-Onset Multiple Sclerosis Demonstrates Potential Biomarkers For Unclassified Patients, İsmai̇l Solmaz, Ozan Kaplan, Mustafa Çelebi̇er, İnci̇lay Lay, Fatma Banu Anlar

Turkish Journal of Medical Sciences

Background/aim: Metabolomics has the potential to provide putative biomarkers and insights into the pathophysiology and diagnosis of pediatric multiple sclerosis (pMS), which is an inflammatory demyelinating disorder of the central nervous system with a broad spectrum of clinical manifestations. In this study, we aimed to investigate serum metabolomics in pMS to help elucidate the pathophysiology of MS. Materials and methods: An untargeted approach was applied using the quadrupole time-of-flight liquid chromatography/mass spectrometry (Q-TOF LC/MS) method to study plasma metabolites in patients with pMS (n = 33), patients with unclassified central nervous system demyelinating diseases (n = 6), and age-matched healthy …


Do We Need Postoperative Antibiotics In Supratentorial Clean Neurosurgery? A Prospective, Randomized, Single-Blind, And Placebo-Controlled Study, Taha Şükrü Korkmaz, Tufan Agah Kartum, Gülçi̇n Baş, Eren Fatma Akçil, Rahşan Kemerdere, Seher Naz Yeni̇, Taner Tanriverdi̇ Jan 2022

Do We Need Postoperative Antibiotics In Supratentorial Clean Neurosurgery? A Prospective, Randomized, Single-Blind, And Placebo-Controlled Study, Taha Şükrü Korkmaz, Tufan Agah Kartum, Gülçi̇n Baş, Eren Fatma Akçil, Rahşan Kemerdere, Seher Naz Yeni̇, Taner Tanriverdi̇

Turkish Journal of Medical Sciences

Background/aim: To assess the efficacy of postoperative antibiotics on postoperative infection in clean supratentorial craniotomies. Material and methods: This study is a prospective, randomized, single-blind, and placebo-controlled clinical trial that included consecutive patients who underwent clean supratentorial craniotomy between November 2017 and September 2020 and evaluated the effectiveness of postoperative antibiotic prophylaxis on postoperative infection. Results: A total of 80 patients were included and the whole group was divided into two groups. Group A included patients who received antibiotic prophylaxis and group B who did not receive antibiotic prophylaxis after surgery. Each group included the same number of patients (40 …


Performance Of Indirect Immunofluorescence Test And Immunoblot Tests In The Evaluation Of Antinuclear And Antimitochondrial Antibodies, Ömer Öztürk, Selay Demi̇rci̇ Dos Santos Duarte, Hati̇ce Yasemi̇n Balaban, Hali̇s Şi̇mşek, Burçi̇n Şener Jan 2022

Performance Of Indirect Immunofluorescence Test And Immunoblot Tests In The Evaluation Of Antinuclear And Antimitochondrial Antibodies, Ömer Öztürk, Selay Demi̇rci̇ Dos Santos Duarte, Hati̇ce Yasemi̇n Balaban, Hali̇s Şi̇mşek, Burçi̇n Şener

Turkish Journal of Medical Sciences

Background/aim: Antinuclear antibodies (ANA) and antimitochondrial antibodies (AMA) have essential markers for the diagnosis of autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC). These autoantibodies are detecting different laboratory methods. In this study, we studied the diagnostic performance of used methods in detecting ANA and AMA. Materials and methods: The autoantibody profiles of patients with AIH and PBC groups were analyzed with the indirect immunofluorescence test (IIF) and liver-specific antigens containing immunoblot test (IB). Results: There were 45 (87%) women in the study group and 8 (53%) women in the control group. The mean age of the patients was 50.5 …


Causes Of Severe Infections In Patients With Systemic Sclerosis And Associated Factors, Müçteba Enes Yayla, Emi̇ne Uslu Yurteri̇, Murat Torğutalp, Di̇dem Şahi̇n Eroğlu, Serdar Sezer, Ayşe Bahar Keleşoğlu Di̇nçer, Emi̇ne Gözde Aydemi̇r Gülöksüz, Mehmet Levent Yüksel, Recep Yilmaz, Aşkin Ateş, Tahsi̇n Murat Turğay, Gülay Kinikli Jan 2022

Causes Of Severe Infections In Patients With Systemic Sclerosis And Associated Factors, Müçteba Enes Yayla, Emi̇ne Uslu Yurteri̇, Murat Torğutalp, Di̇dem Şahi̇n Eroğlu, Serdar Sezer, Ayşe Bahar Keleşoğlu Di̇nçer, Emi̇ne Gözde Aydemi̇r Gülöksüz, Mehmet Levent Yüksel, Recep Yilmaz, Aşkin Ateş, Tahsi̇n Murat Turğay, Gülay Kinikli

Turkish Journal of Medical Sciences

Background/aim: Systemic sclerosis (SSc) is a chronic systemic disease characterized by vascular damage, autoimmunity, and fibrosis in the skin and internal organs. In this study, we tried to determine the causes of severe infection in patients with SSc and to reveal the factors associated with severe infection. Materials and methods: We retrospectively examined 214 SSc patients between January 2010 and August 2020. Forty-seven patients with at least one severe infection and 167 patients without severe infection were compared. Results: A total of 76 episodes of severe infections were detected in 47 (22%) patients. Common infections included pneumonia, infected digital ulcer, …


The Effectiveness Of Anti-Interleukin-1 Therapy On Subclinical Inflammation Parametersduring The Attack-Free Period In Familial Mediterranean Fever Patients: A Case-Control Study, Ebru Atalar, İsmai̇l Doğan, Kevser Gök, Serdar Can Güven, Yüksel Maraş, Gülay Güleç Ceylan, Şükran Erten Jan 2022

The Effectiveness Of Anti-Interleukin-1 Therapy On Subclinical Inflammation Parametersduring The Attack-Free Period In Familial Mediterranean Fever Patients: A Case-Control Study, Ebru Atalar, İsmai̇l Doğan, Kevser Gök, Serdar Can Güven, Yüksel Maraş, Gülay Güleç Ceylan, Şükran Erten

Turkish Journal of Medical Sciences

Background/aim: Anti IL-1 therapy is useful in suppressing attacks in FMF patients with colchicine resistance, however, it is not certain whether subclinical inflammation can sufficiently be inhibited with anti-IL-1 therapy in FMF patients with amyloidosis. Materials and methods: Forty-six FMF patients receiving anti-interleukin-1 therapy and 36 healthy control patients were compared in terms of laboratory parameters. Also, FMF patients were further divided into two groups; those with amyloidosis and those without it, and these subgroups were compared to each other in terms of clinical and laboratory findings. Results: In comparison between the FMF and healthy control groups, erythrocyte sedimentation rate …


Pertussis Prevalence Among Adult Patients With Acute Cough, Ahmet İlbay, Mi̇ne Durusu Tanriöver, Işkin Pinar Zarakol, Ezgi̇ Çalişkan Güzelce, Hati̇ce Bölek, Serhat Ünal Jan 2022

Pertussis Prevalence Among Adult Patients With Acute Cough, Ahmet İlbay, Mi̇ne Durusu Tanriöver, Işkin Pinar Zarakol, Ezgi̇ Çalişkan Güzelce, Hati̇ce Bölek, Serhat Ünal

Turkish Journal of Medical Sciences

Background/aim: Bordetella pertussis infection remains an important health problem in adults due to the increasing prevalence in recent years. Pertussis in adults can be easily overlooked or misdiagnosed. We aimed to determine the prevalence of pertussis in adult patients with acute cough and the clinical features of the pertussis cases. Materials and methods: Internal Medicine and Pulmonology inpatient wards and outpatient clinics were screened between March 2017 and June 2018. Patients with cough duration between 1 week and 1 month were enrolled. Those who were on antibiotics for more than 5 days were excluded. A total of 115 patients were …


Assessment Of Subclinical Cardiovascular Alterations In Non-Functioning Adrenal Incidentalomas, Bülent Can, Peli̇n Karaca Özer, Büşra Can, Özge Telci̇ Çaklili Jan 2022

Assessment Of Subclinical Cardiovascular Alterations In Non-Functioning Adrenal Incidentalomas, Bülent Can, Peli̇n Karaca Özer, Büşra Can, Özge Telci̇ Çaklili

Turkish Journal of Medical Sciences

No abstract provided.


Application Of High-Flow Oxygen Therapy In Acute Pancreatitis Complicated With Acute Respiratory Dysfunction, Xiang Ji, Jie Zhou, Wenting Wu, Yan Tang, Tongrong Xu Jan 2022

Application Of High-Flow Oxygen Therapy In Acute Pancreatitis Complicated With Acute Respiratory Dysfunction, Xiang Ji, Jie Zhou, Wenting Wu, Yan Tang, Tongrong Xu

Turkish Journal of Medical Sciences

No abstract provided.


Investigation Of Cochlear Microphonics Recorded With Different Stimulus Types, Özgecan Güneşer, Ayşe Arzu Yi̇ği̇t, Asuman Alniaçik, Kürşat Yanarateş, Eda Çakmak Jan 2022

Investigation Of Cochlear Microphonics Recorded With Different Stimulus Types, Özgecan Güneşer, Ayşe Arzu Yi̇ği̇t, Asuman Alniaçik, Kürşat Yanarateş, Eda Çakmak

Turkish Journal of Medical Sciences

Background/aim: Electrocochleography (ECochG), one of the first defined tests under auditory evoked potentials, is a total electrical response of inner and outer hair cells inside the cochlea and auditory nerve record technique to the presence of an acoustic stimulus. T hese records can be used in Meniere disease and auditory neuropathy spectrum disorder diagnosis, intraoperative monitoring. In addition, the presence of cochlear microphonics plays a crucial role in auditory neuropathy spectrum disorder diagnosis. In our study, healthy individuals were tested with extratimpanic electrocochleography record method via Click and LS CE-Chirp stimulus, and the results were compared to the age, sex, …


Morphometric Examination Of Trigeminal Nerve And Its Adjacent Structures In Patients With Trigeminal Neuralgia: A Case-Control Study, Yunus Emre Kundakci, Nadi̇re Ünver Doğan, İnci̇ Kara, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Ahmet Kağan Karabulut Jan 2022

Morphometric Examination Of Trigeminal Nerve And Its Adjacent Structures In Patients With Trigeminal Neuralgia: A Case-Control Study, Yunus Emre Kundakci, Nadi̇re Ünver Doğan, İnci̇ Kara, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Ahmet Kağan Karabulut

Turkish Journal of Medical Sciences

Background/aim: Morphological differences that can lead the trigeminal nerve to neurovascular conflict and a new solitary pontine lesion are associated with the pathogenesis of trigeminal neuralgia (TN). In this case-control study, we aimed to contribute to the current discussions about the pathogenesis of TN by investigating the anatomical structures that may have an effect on the morphometric parameters of the trigeminal nerve. Materials and methods: This study included 25 patients with TN followed up for pain in the Department of Algology, Faculty of Medicine, and 25 age- and gender-matched controls. We performed morphometric measurements including the length and volume of …


Venom Immunotherapy And Difficulties Encountered Before And During Immunotherapy: Double Sensitization, Systemic Reactions, Treatment With Omalizumab, And High Dose Vit, Gülden Paçaci Çeti̇n, İnsu Yilmaz, Murat Türk, Bahar Arslan, Saki̇ne Nazi̇k Bahçeci̇oğlu Jan 2022

Venom Immunotherapy And Difficulties Encountered Before And During Immunotherapy: Double Sensitization, Systemic Reactions, Treatment With Omalizumab, And High Dose Vit, Gülden Paçaci Çeti̇n, İnsu Yilmaz, Murat Türk, Bahar Arslan, Saki̇ne Nazi̇k Bahçeci̇oğlu

Turkish Journal of Medical Sciences

Background/aim: Venom immunotherapy (VIT) is the most effective treatment method to prevent recurrent systemic reactions to Hymenoptera stings. In this study, the demographic characteristics of VIT patients, the success rates of VIT, the difficulties we encountered during VIT, and solutions for these difficulties in our clinic were presented. Materials and methods: We retrospectively analyzed patients with venom allergy who applied venom immunotherapy between 2013- 2020. Data on age, gender, Hymenoptera species with the first reaction, grade of the reaction, beekeeping history, skin prick and specific IgE and component results, double sensitization, blood groups, and reactions with VIT and/or sting during …


Could Computed Tomography Histogram Analysis Add Value To The Diagnosis Of Cholesteatoma?, Nursel Yurttutan, Nagi̇han Bi̇lal, Betül Kizildağ, Adem Doğaner Jan 2022

Could Computed Tomography Histogram Analysis Add Value To The Diagnosis Of Cholesteatoma?, Nursel Yurttutan, Nagi̇han Bi̇lal, Betül Kizildağ, Adem Doğaner

Turkish Journal of Medical Sciences

Background/aim: To investigate the potential role of computed tomography (CT) histogram analysis in differentiating cholesteatoma (CHS) and non-cholesteatoma (NCHS). Materials and methods: We evaluated 77 temporal bone CT images (from November 2016 to February 2020) that were obtained pre- operatively (mean age, 37.10±17.27 years in CHS; 36.72±16.08 years in NCHS group). Histogram analyses of the resulting XML files were conducted using the R Project 3.3.2 program. ROC analysis was used to find threshold values, and the diagnostic efficiency of these values in differentiating CHS-NCHS was determined. Results: The CT images of 41 CHS (53.25%) and 36 NHCS cases (46.75%) were …


Tp-E Interval, Tp-E/Qt, And Tp-E/Qtc Ratios In Patients With Primaryhyperparathyroidism And Their Relationship With Cardiac Arrhythmic Events, Yücel Yilmaz, Şaban Keleşoğlu, Ferhat Gökay, Yasi̇n Şi̇mşek Jan 2022

Tp-E Interval, Tp-E/Qt, And Tp-E/Qtc Ratios In Patients With Primaryhyperparathyroidism And Their Relationship With Cardiac Arrhythmic Events, Yücel Yilmaz, Şaban Keleşoğlu, Ferhat Gökay, Yasi̇n Şi̇mşek

Turkish Journal of Medical Sciences

Background/aim: Primary hyperparathyroidism (PHPT) is an endocrine disorder characterized by hypercalcemia caused by excessive parathyroid hormone (PTH) secretion from the parathyroid gland. PHPT was previously shown to increase cardiac arrhythmias. Besides, new indices, such as the Tpeak-Tend (Tp-e) interval, Tp-e interval/QT interval (Tp-e/QT) ratio, and Tp-e interval/corrected QT interval (Tp-e/QTc) ratio may be associated with ventricular arrhythmias and sudden cardiac death. Therefore, we aimed to investigate the relationship between PHPT and the changes to Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio. Materials and methods: We carried out the study with 41 patients with PHPT and 40 control subjects. We calculated …


Breed, Age, And Sex-Related Variations In Hematological And Some Biochemicalparameters In The Tornjak Dog, Ivona Alilovic, Dunja Rukavina, Atifa Ajanovic, Cazim Crnkic, Husein Ohran, Amir Zahirovic Jan 2022

Breed, Age, And Sex-Related Variations In Hematological And Some Biochemicalparameters In The Tornjak Dog, Ivona Alilovic, Dunja Rukavina, Atifa Ajanovic, Cazim Crnkic, Husein Ohran, Amir Zahirovic

Turkish Journal of Veterinary & Animal Sciences

There is an increasing significance for the breed, age, and sex-related variations in hematological and biochemical parameters in veterinary medicine. The primary objective of this study was to identify possible breed-related differences and to determine the effect of age and sex on hematologic and serum biochemical parameters in the Bosnian and Herzegovinian - Croatian Shepherd dog Tornjak raised in Bosnia and Herzegovina (B&H). Data from 19 hematological and 17 serum biochemical parameters were analyzed in the group of 100 dogs (47 females and 53 males), sexually intact and aged between one month and twelve years. Breed affected TP (total protein) …


A Survey Of Ixodid Ticks In Stray Dogs And Molecular Detection Of Ehrlichia Canis Fromticks In Central Iran, Hosein Khovand, Saeid Reza Nourollahi Fard, Mohammad Khalili, Maziar Jajarmi Jan 2022

A Survey Of Ixodid Ticks In Stray Dogs And Molecular Detection Of Ehrlichia Canis Fromticks In Central Iran, Hosein Khovand, Saeid Reza Nourollahi Fard, Mohammad Khalili, Maziar Jajarmi

Turkish Journal of Veterinary & Animal Sciences

Ticks are well known as hematophagous ectoparasites, which cause different diseases in humans and animals. This investigation was designed in central Iran to assess the prevalence, intensity, and abundance of tick infestation in stray dogs and detection of Ehrlichia canis. Overall, 962 ticks were collected from 260 stray dogs between April and August 2018. DNA samples with the goal of amplification of pathogen were screened by real-time PCR assay. The prevalence of tick infestation on stray dogs was 60.3%. Rhipicephalus sanguineus sensu lato (s.l.) was only species found in stray dogs. Out of 42 tick pools, 4 (9.5%) were positive …


Some Hematological Parameters And Enzyme Histochemistry Of Peripheral Bloodleukocytes In Kivircik Sheep, Mehmet Faruk Aydin, İhsan Kisadere Jan 2022

Some Hematological Parameters And Enzyme Histochemistry Of Peripheral Bloodleukocytes In Kivircik Sheep, Mehmet Faruk Aydin, İhsan Kisadere

Turkish Journal of Veterinary & Animal Sciences

The aim of the present study was to determine some hematological parameters (RBC, WBC, HCT, HGB, MCH, MCHC, MCV, and PLT), the presence and percentages of ANAE and AcP-ase positivities in leukocytes and the differential leukocyte count in Kivircik sheep. Blood samples were taken from the jugular vein of 40 (rams = 20; ewes= 20) healthy, 1-year-old sheep. MCH and MCHC values were found statistically higher in rams than ewes (p < 0.05). Mean percentages of ANAE-positive PBL were defined as 74.16 ± 11.94% in ewes and 70.33 ± 8.39% in rams. It was not determined any significant changes according to sex. On the other hand, the percentages of ACP were determined as 67.12 ± 6.54% in ewes and 66.71 ± 6.58% in rams. It was not found any significant differences according to sex. For ANAE enzyme activity, lymphocytes, monocytes, neutrophils, and eosinophilic granulocytes showed a positive reaction. For ACP enzyme activity, although lymphocytes presented positivity, monocytes, neutrophils, eosinophils were negative. The ratio of lymphocyte, monocyte, neutrophile, eosinophile, and basophile of Kivircik ewes and rams were found as 64.35 ± 5.74%, 60.64 ± 8.85%; 3.41 ± 1.27%, 3.82 ± 1.42%; 27.58 ± 5.46%, 30.94 ± 8.71%; 2.41 ± 0.93%, 2.88 ± 1.45%; 1.76 ± 0.75%, 1.29 ± 0.58%, respectively. The difference between mean values was not found significant according to sex (p > 0.05). In conclusion, our study showed that enzyme histochemical methods can be used for identifying peripheral blood cells and can provide facilitates for early diagnosis of immune system-related disorders …


Determination Of The Morphometric Characteristics Of Donkey (Equus Asinus)Populations Reared In Turkey, Eser Kemal Gürcan, Serdar Genç, Selçuk Kaplan, Fulya Özdi̇l, Emel Özkan Ünal, Hasan Bulut, Selen Yatkin, Sezen Arat, Mehmet İhsan Soysal Jan 2022

Determination Of The Morphometric Characteristics Of Donkey (Equus Asinus)Populations Reared In Turkey, Eser Kemal Gürcan, Serdar Genç, Selçuk Kaplan, Fulya Özdi̇l, Emel Özkan Ünal, Hasan Bulut, Selen Yatkin, Sezen Arat, Mehmet İhsan Soysal

Turkish Journal of Veterinary & Animal Sciences

This research aims to determine the morphometric characteristics of the donkey (Equus asinus) populations reared in Turkey. For this purpose, live weights and body measurements were collected from 500 donkeys. The donkeys were grouped according to the factors of color, age, sex, and province and the live weights (LW) (kg), withers heights (WH), rump heights (RH), body lengths (BL), chest circumferences (CC), chest depths (CD), front shank circumferences (FSC), head lengths (HL) and ear lengths (EL) (cm) of the donkeys were measured. In the study, the males were found to have higher values of live weight, withers height, rump height, …


Melanocytes As The Source Of The Increased Melanisation In Pigmented Epithelial Tumours: A Holistic Approach, Asuman Ki̇li̇tci̇, Ömer Faruk Elmas, Necmetti̇n Akdeni̇z, Mehmet Gamsizkan Jan 2022

Melanocytes As The Source Of The Increased Melanisation In Pigmented Epithelial Tumours: A Holistic Approach, Asuman Ki̇li̇tci̇, Ömer Faruk Elmas, Necmetti̇n Akdeni̇z, Mehmet Gamsizkan

Turkish Journal of Medical Sciences

No abstract provided.


The Reliability And Validity Of The Turkish Version Of The Multiple Sclerosis Impact Scale-29, Fati̇h Özden, Mehmet Özkeski̇n, Ayşe Nur Yüceyar Jan 2022

The Reliability And Validity Of The Turkish Version Of The Multiple Sclerosis Impact Scale-29, Fati̇h Özden, Mehmet Özkeski̇n, Ayşe Nur Yüceyar

Turkish Journal of Medical Sciences

Background/aim: The purpose of the study was to cross-culturally adapt the Multiple Sclerosis Impact Scale-29 (MSIS-29) into Turkish and evaluate its reliability and validity in patients with Multiple Sclerosis (MS). Materials and methods: A total of 119 individuals with MS were enrolled in the research. The neurologist classified the patients with Expanded Disability Status Scale (EDSS). In the initial evaluation, patients completed the Multiple Sclerosis Impact Scale-29 (MSIS29), the Multiple Sclerosis International Quality of Life (MusiQoL), EuroQol-5D-3L (EQ-5D-3L), and Beck Depression Scale (BDS), respectively one week later, the MSIS-29 evaluation was repeated. Internal consistency, test-retest reliability, and construct validity were …


Low-Dose Valacyclovir Use With Preemptive Monitoring In Kidney Transplant Recipients With Intermediate Cytomegalovirus Infection Risk, Arzu Veli̇oğlu, Selma Alagöz, Di̇lek Barutçu Ataş, İzzet Hakki Arikan, Ebru Aşicioğlu, Mehmet Burak Aksu, Nurhan Seyahi̇, Zübeyde Serhan Tuğlular Jan 2022

Low-Dose Valacyclovir Use With Preemptive Monitoring In Kidney Transplant Recipients With Intermediate Cytomegalovirus Infection Risk, Arzu Veli̇oğlu, Selma Alagöz, Di̇lek Barutçu Ataş, İzzet Hakki Arikan, Ebru Aşicioğlu, Mehmet Burak Aksu, Nurhan Seyahi̇, Zübeyde Serhan Tuğlular

Turkish Journal of Medical Sciences

No abstract provided.


Determination Of Mir-373 And Mir-204 Levels In Neuronal Exosomes In Alzheimer?S Disease, Eli̇fcan Taşdelen, Erguvan Tuğba Özel Kizil, Sabi̇ha Tezcan Aydemi̇r, Ömer Eray Yalap, Ayşe Petek Bi̇ngöl, Nüket Kutlay Jan 2022

Determination Of Mir-373 And Mir-204 Levels In Neuronal Exosomes In Alzheimer?S Disease, Eli̇fcan Taşdelen, Erguvan Tuğba Özel Kizil, Sabi̇ha Tezcan Aydemi̇r, Ömer Eray Yalap, Ayşe Petek Bi̇ngöl, Nüket Kutlay

Turkish Journal of Medical Sciences

Background/aim: NLRP3 inflammasome activation has been known to be involved in the etiology and progression of Alzheimer?s disease (AD). Furthermore, AD and diabetes mellitus have common pathomechanisms. It has been shown that P2X7R whose expression is increased in brain tissues with AD and plays a role in the activation of NLRP3 inflammasome is suppressed by miR-373 in patients with osteoarthritis. Therefore, the question of whether the suppressive effect of miR-373 on NLRP3 may have a role in the pathophysiology of AD comes to mind. On the other hand, it is known that the miR-204 level increases in response to TXNIP, …


Ultrasound-Guided Rhomboid Intercostal Block For Myofascial Pain Syndrome: A Prospective Clinical Study, Seli̇n Güven Köse, Hali̇l Ci̇han Köse, Serkan Tulgar, Ömer Taylan Akkaya Jan 2022

Ultrasound-Guided Rhomboid Intercostal Block For Myofascial Pain Syndrome: A Prospective Clinical Study, Seli̇n Güven Köse, Hali̇l Ci̇han Köse, Serkan Tulgar, Ömer Taylan Akkaya

Turkish Journal of Medical Sciences

Background/aim: Myofascial pain syndrome (MPS) is a common chronic pain syndrome that may affect quality of life, daily living activities, and psychological status. Ultrasound (US)-guided rhomboid intercostal block (RIB) is a recently defined plane block and used for chronic pain such as postmastectomy syndrome and MPS. Our aim was to evaluate the efficacy of US-guided RIB for the management of pain, quality of life, physical disability, and patient satisfaction in MPS. Materials and methods: In this prospective study, between February and March 2021, a total of 30 patients who applied with the diagnosis of MPS, were included. The patients received …


Interstitial Lung Disease In Patients With Systemic Lupus Erythematosus: A Cohort Study, Naci̇ Şenkal, Esen Kiyan, Ali̇ Aslan Demi̇r, Yasemi̇n Yalçinkaya, Ahmet Gül, Murat İnanç, Mahdume Lale Öçal, Bahar Artim Esen Jan 2022

Interstitial Lung Disease In Patients With Systemic Lupus Erythematosus: A Cohort Study, Naci̇ Şenkal, Esen Kiyan, Ali̇ Aslan Demi̇r, Yasemi̇n Yalçinkaya, Ahmet Gül, Murat İnanç, Mahdume Lale Öçal, Bahar Artim Esen

Turkish Journal of Medical Sciences

Background/aim: Systemic lupus erythematosus (SLE) is an autoimmune disease with a variety of organ/system involvement. Respiratory system involvement is common in these patients and usually manifests itself by disorders of the lung parenchyma, pleura, pulmonary vasculature or diaphragm. In this study, we sought to determine the frequency of interstitial lung disease (ILD) in patients with SLE and associated risk factors. Materials and methods: Three hundred randomly chosen patients with SLE were included. Chest x-ray (CXR), lung spirometry and carbon monoxide diffusion test (DLCO) were performed. High-resolution thorax computed tomography (HRCT) was performed for a definite diagnosis of ILD. Results: Of …