Digital Commons Network^™

The Musical Touch On Mental Illness, Skylar Dunn

Senior Honors Theses

To understand the relationship amongst anxiety, depression, and music therapy, this integrative review synthesizes the major themes and relevant education of articles discussing mental health and the benefit of music. While most existing studies focus on using music therapy to treat pain and clinical anxiety, the content of this paper is written to emphasize how the same principles can be used in unmanageable stress and emotional decomposition. Each topic is analyzed and reviewed individually, pooling several sources for a thorough examination, and understanding of the subject. Once each area is fully summarized, the gap is addressed by pulling evidence from …

Synthesis And Characterization Of Some Disubstituted Cyclopentadienyl Rhenium Complexes As Potential Candidates In Semiconductive Materials, Chloe Vernon

Senior Honors Theses

Since 2000, when the Nobel Prize in Chemistry as awarded for conductive polymer research few studies have been performed concerning the conductive capabilities of discrete organometallic compounds. For this project, organometallic compounds were formed specifically with a transition metal included in the structure. Through oxidation and reduction reactions, the variation in the electrical conductivity could allow for an analysis of whether this unique structure would allow for tunability. The goal of this research was to begin with aromatic substituted fulvenes and perform various multistep synthesis processes, utilizing thallium salt intermediates, to produce several disubstituted cyclopentadienyl rhenium complexes. In this project, …

Child Abuse From A Nursing Perspective: Assessment And Implications, Ashtyn Spring

Senior Honors Theses

Nurses experience the relationship dynamics between pediatric patients and their families firsthand. Being informed by the goals of holistic care, nurses should be assessing for unhealthy dynamics among pediatric patients and their caregivers so they can respond appropriately when a potential for abuse is present. Healthcare workers have the duty to provide safety and healing to their patients. Through the unique contact nurses have with patients, their training for accurate assessment skills, and their responsibility as healthcare workers, nurses are placed with the opportunity to help children out of abusive situations. Prompt identification of the potential for abuse can prevent …

The Revolutionary Genome Editor: Crispr-Cas9 Systems, Grace Spade

Senior Honors Theses

Genetic engineering is the modification of an organism's genetic material to alter its traits through adding, deleting, or changing specific genes. CRISPR-Cas9 systems are groundbreaking tools for genetic engineering, in short utilizing a molecule called RNA to guide a protein called Cas9 to a specific location in DNA to add, delete, or replace genes. The history of how the CRISPR-Cas9 systems came into existence, how it was adapted from a natural defense system in bacteria, and its mechanism of action in both are explained. Its applications, both present and future, competing genetic modifiers, advantages and disadvantages, and the ethical dilemmas …

Mandates, Mistrust, And Misconceptions: An Overview Of Vaccine Hesitancy, Evelyn Ryan

Senior Honors Theses

Vaccines are one of the most successful ways to prevent diseases and are considered one of the most influential achievements in the history of public health. While vaccines have many benefits, the number of parents that refuse vaccinations for their children is increasing. People are concerned about potential risks and health problems that are thought to result from vaccination. There are risks and contraindications involved with vaccines, but many reasons for vaccine hesitancy that are cited by the public are not founded on evidence-based data. When making vaccine decisions, it is essential that the public has accurate information and that …

Pathogenesis And Therapeutics Of Huntington's Disease, Megan Bones

Senior Honors Theses

Huntington’s disease (HD) is a rare, incurable, inherited neurological disease that causes the progressive breakdown of nerve cells in the brain. The mutant huntingtin gene contains 40 to 80 repeats of a CAG trinucleotide sequence. The pathogenesis of HD is multifaceted and includes pathways related to glutamine aggregation, mitochondrial and oxidative stress, mitochondrial dysfunction, and DNA damage. Currently two drugs, tetrabenazine and deutetrabenazine, are FDA approved for the treatment of HD. Otherwise, medications given to HD patients include general antipsychotics, antidepressants, and mood-stabilizer drugs. Other treatment methods include speech and physical therapy. This research provides an understanding of the various …

In Vitro Gametogenesis: A Research Timeline And Implications For The Future Of Assisted Reproductive Technology, Nicole Buckley

Senior Honors Theses

The novel reproductive technology, In Vitro Gametogenesis (IVG), includes the process of obtaining mature viable germ cells from pluripotent stem cells. To do so, embryonic stem cells and induced pluripotent stem cells are specified to primordial germ cells and differentiated to form gametes that undergo further maturation, which subsequently may undergo in vitro fertilization to form an embryo. With this capability, IVG holds the power to provide a novel treatment option for human infertility. As of now, research has been conducted on mice successfully, and with limited success in humans. Future research will likely focus on discovering the species-specific differences …

Health Consequences Of Low Energy Availability In Females And Their Underlying Physiological Mechanisms, Grace Parry

Senior Honors Theses

Low energy availability (LEA) is a state in which energy intake is insufficient to support energy expenditure while maintaining energy balance, which has been shown to result in gastrointestinal distress, immunosuppression, reduced metabolic rate, menstrual dysfunction, diminished bone health, and impaired cardiovascular function in females. Alterations to the microbiome and mucosal lining may propagate gastrointestinal complaints and compromised immune function associated with LEA. The pathophysiology of LEA is otherwise largely driven by hormonal adaptations. Diminished production of thyroid hormones is known to contribute to reduced metabolic rate. Decreases in leptin and insulin and increases in ghrelin disrupt reproductive function through …

Efficacy Of Kidney Reperfusion Treatments Relative To Function And Survival Rates After Transplantation, Mitchell Rohr

Senior Honors Theses

Donor kidneys are damaged upon circulatory death before being preserved with machine perfusion until transplantation. During machine perfusion, blood is pumped back into the vasculature of the kidney, causing damage called ischemic reperfusion injury. The two forms of machine perfusion are hypothermic machine perfusion and normothermic machine perfusion. Different methods of treatment can be used during either hypothermic machine perfusion or normothermic machine perfusion to prevent ischemic reperfusion injury. Each of the treatment methods that were reviewed showed potential for preventing ischemic reperfusion injury, with hypothermic treatments having higher average levels of feasibility than normothermic treatments. The effect of the …

Virtue Ethics In Nursing: A Review Of The Literature, Abigail Chu

Senior Honors Theses

Background

Human flourishing is at the heart of healthcare. In Nicomachean Ethics, Aristotle proposes virtue ethics, the idea that humans find and fulfill their purpose through flourishing. Virtue ethics posits that an individual flourishes by forming habits that promote excellence (both moral excellence and excellence in skill) while modeling people who possess the ideal traits. Virtue ethics emphasizes eudaimonia or human flourishing as embodying the highest good and an overall state of wellbeing.

Purpose

The purpose of this integrative literature review is to examine how virtue ethics in nursing can promote human flourishing.

Methods

Twenty-nine articles were reviewed for …

Nursing Care Of Family Caregivers: Interventions And Considerations Regarding Current Issues Facing Family Caregivers Of Persons With Dementia Relevant To Nursing Practice, Alayna Kent

Senior Honors Theses

There are an estimated 6.5 million Americans age 65 and older who are currently living with Alzheimer’s dementia. A large majority of these individuals receive care from a nonprofessional family caregiver, typically in the home setting. It is well documented that family caregivers of dementia patients experience many unique challenges. These challenges provide valuable opportunities for nurses to provide helpful interventions to aid this vulnerable population. An integrated review of the recent literature was conducted, and articles were chosen by a method modeled after the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowsheet. The research was then analyzed …

Where Do We Draw The Line? The Ethical Dilemma Involved In Genetic Engineering And Gene Therapy, Amber Schrag

Senior Honors Theses

Genetic engineering and gene therapy are greatly disputed in our time. With the advancement of technology, one has the power to manipulate genes in the body, which raises the questions: What is our role in this? Is there a limit to this power, or should there be? This paper reviews the uses of this technology and evaluates the ethics from a scientific and Biblical point of view. It is concluded that using gene therapy to help cure diseases is very beneficial in both the scientific and Biblical realm as it is restoring individuals back to health and wholeness.

Prevalence Of Sars-Cov-2 Antibodies In Liberty University Student Population, Emily Bonus

Senior Honors Theses

In 2020, the virus SARS-CoV-2 gained attention as it spread around the world. Its antibodies are poorly understood, and little research focuses on those with few COVID-19 complications yet large numbers of close contacts: university students. This longitudinal study recorded SARS-CoV-2 antibody presence in 107 undergraduate Liberty University students twice during early 2021. After extensive data cleaning and the application of various statistical tests and ANOVAs, the data seems to show that in the case of COVID-19 infections, SARS-CoV-2 IgM antibodies are immediately produced, and then IgG antibodies follow later. However, the COVID-19 vaccine causes the production of both IgM …

Home Exercise Program Adherence In Physical Therapy: Application Of The Transtheoretical Model, Charis Brown

Senior Honors Theses

Home exercise programs (HEPs) are a foundational component of physical therapy (PT). However, the majority of patients are not compliant with their HEP; they lack the motivation and habits necessary to be compliant. The transtheoretical model (TTM) is a framework for understanding the decision-making of the individual and is a model of intentional change. When properly understood and applied, the TTM can improve a physical therapist’s ability to help patients to change their behavior and to become HEP compliant. This paper seeks to address patient exercise noncompliance by educating and instructing physical therapists in the application of the TTM, which …

Determining The Impact Of Nurse Residency Programs To Increase Retention Rate Among New Nurse Graduates: An Integrative Review, Guiselly Astrid Erazo-Romero

Doctoral Dissertations and Projects

New nurse graduates account for the largest group entering the profession, but they also have the lowest retention rates among all nursing staff. Due to the nursing shortage, newly licensed nurses undergo a shorter orientation to meet the complex needs of healthcare. Newly licensed nurses often report feelings of unpreparedness, lack of competence, and lack of confidence as they are expected to care for patients with complex needs. In response to the concern over low retention rates and the preparation-practice gap among new graduate nurses, Nurse Residency Programs (NRPs) were implemented. This program further eases the transition from the student …

Teamstepps And Organizational Culture, Amelia Arca Quinto

Doctoral Dissertations and Projects

Patient safety issues remain despite several strategies developed for their deterrence. While many safety initiatives bring about improvement, they are repeatedly unsustainable and short-lived. The index hospital’s goal was to build an organizational culture within a groundwork that improves teamwork and continuing healthcare team engagement. Teamwork influences the efficiency of patient care, patient safety, and clinical outcomes, as it has been identified as an approach for enhancing collaboration, decreasing medical errors, and building a culture of safety in healthcare. The facility implemented Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS), an evidence-based framework which was used for …

Increased Prevalence Of Suicide In The Adolescent Population Within The Lgbtq+ Community Compared To Adolescents In The Heterosexual Population: An Integrative Review, Natasha Denese Causey

Doctoral Dissertations and Projects

According to research, young Americans who identify as lesbian, gay, bisexual, transgender, queer, and more (LGBTQ+) are currently experiencing a mental health crisis. Suicide ideations reportedly begin sooner in LGBQ+ adolescents, 13 to 18 years of age. Suicide ideation is defined by the National Alliance of Mental Illness (NAMI), as having serious thoughts about suicide with a plan. This involves LGBTQ+ adolescents shifting from suicidal ideation to planning more quickly than their heterosexual (straight) peers. Adolescents who identify as LGBTQ+ showed a higher lifetime risk of suicide thoughts than their heterosexual peers (26.1 percent to 13 percent, respectively). Additionally, 5.4 …

High Health Care Cost In The U.S. And Its Impact On An African American Church Community In East Orange, New Jersey, William Charles

Doctoral Dissertations and Projects

Access to affordable quality health care has been a long debating issue in the United States. Many scholarly research articles indicated that the cost of insurance premiums, deductibles, co-payments, and prescription drugs continue to rise every year. Despite various efforts to reduce the cost of health care in the United States, the trend remains the same. Au contraire, more Americans are unable to afford the cost of prescription drugs. More Americans postpone their medical treatments. More Americans find it difficult to financially address their health care needs. It can be inferred that high health cost has a significant impact in …

The Impact Of Juvenile Drug Court On Recidivism, Mallory Noelle Watkins

Doctoral Dissertations and Projects

The number of youths entering the juvenile justice system is a viable concern throughout the United States. A gap in the existing literature surrounding juvenile justice is recidivism rates among young offenders who are incarcerated or sanctioned to a community-based level of supervision after committing a transgression of a law. Federal juvenile justice practitioners, such as the Office of Juvenile Justice and Delinquency Prevention (OJJDP), the National Council of Juvenile and Family Court Judges (NCJFCJ), the United States Department of Justice (DOJ), and others, in addition to individual states and localities throughout the United States, have taken various approaches to …

A Transcendental Phenomenological Study: Examining Interprofessional Clinical Learning Experiences To Define The Essential Activities That Will Provide Student Transformation, James David Nash

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the interprofessional education clinical experiences that pharmacy preceptors provide to Doctor of Pharmacy (PharmD) students during the final year of training within four different academic institutions. The theory guiding this study was Kolb’s Experiential Learning Model (ELM) and its four components comprised of concrete experience, reflective observation, abstract conceptualization, and active experimentation. These experiences should incorporate all four components of the model to be true experiential learning events leading to transformation. An extensive literature review was provided to support the research. Transcendental phenomenology was the methodology used, as researchers were …

Mental Health Disorders Among The Adolescent Population In Nigeria: An Integrative Review, Njideka Nkemjika Emenyi

Doctoral Dissertations and Projects

Mental illness is a public health crisis with extensive stigma that has been substantially neglected in Nigeria. The general belief in Nigeria is that mental illness originates from supernatural causes such as possession of evil spirits; hence, individuals with mental illness are left in the hands of “the gods” or traditional healers for help. The prevalence of mental health disorders is high amongst adolescents in Nigeria due to rapid biological, social, and psychological changes that increase their susceptibility to mental health complications. Despite the high prevalence of mental illness among Nigerian adolescents, mental health care access and utilization in this …