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Periodontal Regeneration Of Dehisence Defects Using A Modified Perforated Collagen Membrane. A Comparative Experimental Study, Rania Fahmy, Gehan S. Kotry, Omneya R. Ramadan

Future Dental Journal

Placement of occlusive barrier membranes in guided tissue regeneration procedures is thought to deprive the wound area from the regenerative capacity of periosteal and gingival mesenchymal stem cells. The current study was performed to determine the effect of perforated collagen membranes in enhancing periodontal tissue regeneration when compared to conventional occlusive barriers. Sixteen critical-sized dehiscence defects (4×5 mm) were surgically created in the mandibular canine teeth of eight dogs, bilaterally. Eight defects were managed by β-Tricalcium phosphate (β-TCP) alloplast and modified perforated collagen membrane, the contra lateral defects were managed by β-TCP alloplast and occlusive collagen membrane. Dogs were sacrificed …