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Articles 121 - 133 of 133
Full-Text Articles in Entire DC Network
Investigation Of Serum Macrophage Migration Inhibitor Factor And Monocyte Chemotactic Protein-1 Levels In Irritable Bowel Syndrome, Feti̇ Tülübaş, Mustafa Oran, Rafet Mete, Fi̇li̇z Turan, Ahsen Yilmaz, Zeynep Deni̇z Yildiz, Ahmet Gürel
Investigation Of Serum Macrophage Migration Inhibitor Factor And Monocyte Chemotactic Protein-1 Levels In Irritable Bowel Syndrome, Feti̇ Tülübaş, Mustafa Oran, Rafet Mete, Fi̇li̇z Turan, Ahsen Yilmaz, Zeynep Deni̇z Yildiz, Ahmet Gürel
Turkish Journal of Medical Sciences
Irritable bowel syndrome (IBS), a functional disorder of the bowel, has been thought to result from immune activation. The aim of this study was to evaluate macrophage migration inhibitory factor (MMIF) and monocyte chemotactic protein-1 (MCP-1) levels in IBS patients. Materials and methods: We enrolled 30 IBS patients and 30 healthy controls. The MMIF and MCP-1 levels of all patients and controls were detected using commercial enzyme-linked immunosorbent assay kits. Results: Serum MMIF and MCP-1 levels were markedly higher in IBS patients than in controls. White blood cell, neutrophil, lymphocyte, monocyte, eosinophil, and basophil counts did not differ significantly between …
Airway Inflammation And Tiotropium Treatment In Stable Copd Patients, Duygu Özol, Harun Karamanli, Sema Uysal, Muhammet Ramazan Yi̇ği̇toğlu, Zeki̇ Yildirim
Airway Inflammation And Tiotropium Treatment In Stable Copd Patients, Duygu Özol, Harun Karamanli, Sema Uysal, Muhammet Ramazan Yi̇ği̇toğlu, Zeki̇ Yildirim
Turkish Journal of Medical Sciences
Chronic obstructive pulmonary disease (COPD) is an inflammatory disease of the lung associated with progressive airflow limitation. The aim of this study is to assess the influence of tiotropium treatment on airway inflammation and symptoms in stable COPD patients. Materials and methods: Inflammatory markers were measured in the expired breath condensate fluid (EBC) before starting tiotropium treatment and at the end of the first month. Results: Twenty-two patients (81% men) with a mean age of 65.4 ± 10.1 years completed the study. The mean nitrotyrosine and 8-isoprostane levels for oxidative stress markers in EBC before and after treatment were 4.5 …
Evidence-Based Homoeopathy: A Case Of Acute Paraphimosis With Balanitis, Chinta Raveendar, Kishan Banoth
Evidence-Based Homoeopathy: A Case Of Acute Paraphimosis With Balanitis, Chinta Raveendar, Kishan Banoth
Indian Journal of Research in Homoeopathy
Paraphimosis occurs when the foreskin of the uncircumcised or partially circumcised male is retracted behind the glans penis, develops venous and lymphatic congestion and cannot be returned to its normal position. This urological emergency impedes blood flow to the glans penis with potential for permanent damage and gangrene. In infants and young children, paraphimosis usually results from self-manipulation by the child or inappropriate retraction of the foreskin by the caretaker in misguided attempts at cleaning. In the sexually active adolescent or adult male, intercourse is a potential precipitant. Iatrogenic paraphimosis follows cystoscopy or bladder catheterisation if the foreskin is not …
Postoperative Atrial Fibrillation, Oxidative Stress, And Inflammation, Mehmet Özaydin
Postoperative Atrial Fibrillation, Oxidative Stress, And Inflammation, Mehmet Özaydin
Turkish Journal of Medical Sciences
Postoperative atrial fibrillation is the most common complication of cardiac surgery. It is associated with increased complication rates. Recent trials have suggested that inflammation and oxidative stress have key roles in the pathophysiology of atrial fibrillation. Current evidence evaluating the use of antiinflammatory and antioxidant agents, including statins, corticosteroids, N-acetylcysteine, vitamin C, and fish oil, to prevent postoperative atrial fibrillation is promising. However, larger randomized, controlled trials comparing different dose regimens are needed.
The Effects Of 3-Benzoyl-1-Methyl-4-Phenyl-4 Piperidinolhydrochloride (C1), Indomethacin, Nimesulide And Rofecoxib On Cyclooxygenase Activities In Carrageenan-Induced Paw Edema Model, Yaşar Nuri̇ Şahi̇n, Berna Demi̇rcan, Hali̇s Süleyman, Hülya Aksoy, Hali̇se İnci̇ Gül
The Effects Of 3-Benzoyl-1-Methyl-4-Phenyl-4 Piperidinolhydrochloride (C1), Indomethacin, Nimesulide And Rofecoxib On Cyclooxygenase Activities In Carrageenan-Induced Paw Edema Model, Yaşar Nuri̇ Şahi̇n, Berna Demi̇rcan, Hali̇s Süleyman, Hülya Aksoy, Hali̇se İnci̇ Gül
Turkish Journal of Medical Sciences
The aim of this study was to investigate the effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride (C1), which is a structural and also non-classical isomer of bis Mannich base, bis (3-aryl-3-oxo-propyl) methylamine hydrochlorides (B1), on cyclooxygenase (COX) activities in 48 rats with inflammation by using carrageenan-induced paw edema, and to compare its effect with other non-steroidal anti-inflammatory drugs (NSAIDs). Materials and methods: Experimental animals were supplied by the Center of Experimental Research and Practice in Ataturk University. The animals were housed and fed in the laboratory (normal room temparature, food and water) under standard conditions. Rats were randomly assigned to eight groups (n = …
Comparison Of Gliclazide Treatment With Diet Therapy On Acute Phase Protein Levels In Patients With Type 2 Diabetes, Ramazan Memi̇şoğullari, Fati̇h Akçay, Abdurrahman Coşkun, Uğur Korkmaz
Comparison Of Gliclazide Treatment With Diet Therapy On Acute Phase Protein Levels In Patients With Type 2 Diabetes, Ramazan Memi̇şoğullari, Fati̇h Akçay, Abdurrahman Coşkun, Uğur Korkmaz
Turkish Journal of Medical Sciences
Aims: It is known that there is a relationship between diabetic complications and chronic inflammation characterized by alterations in circulating acute phase proteins. It has been emphasized that inflammation contributes to diabetic complications and that gliclazide -an antidiabetic sulfonylurea - decreases the development of such complications. In this study, we aimed to investigate whether gliclazide or diet treatment has an effect on serum levels of acute phase reactants, markers of inflammation. Materials and Methods: Fifty-six newly diagnosed patients with type 2 diabetes and 30 clinically healthy subjects were evaluated prospectively. Twenty-six patients were treated with proper diet and daily gliclazide …
Humoral Immunity And Haemoglobin F (Hbf) Status In Steady State Adult Nigerian Sickle Cell Disease Patients With Asymptomatic Malaria, John Ayodele Olaniyi, Olatubosun Ganiyu Arinola
Humoral Immunity And Haemoglobin F (Hbf) Status In Steady State Adult Nigerian Sickle Cell Disease Patients With Asymptomatic Malaria, John Ayodele Olaniyi, Olatubosun Ganiyu Arinola
Turkish Journal of Medical Sciences
Aim: Nigeria, where malaria is prevalent, has the largest sickle cell gene pool in the world. To this end, there is a need for increased understanding of the pathophysiology of HbSS patients in a malaria endemic zone to reduce mortality. Haematology Department, University College Hospital, Ibadan, Nigeria. Materials and methods: The levels of HbF, IgG, IgA, IgM, transferin (TRF), C-reactive protein (CRP), and haptoglobin (HPT) were determined in 14 Nigerians having HbAA genotype with malaria parasitaemia (HbAA +MP), 17 Nigerians having haemoglobin AA genotype without malaria parasitaemia (HbAA -MP), 15 Nigerians having haemoglobin SS genotype without malaria parasitaemia (HbSS -MP), …
Involvement Of 5-Ht2a Receptor In Chronic Inflammatory Pain, M. Kaewwongse, Le Grand Sm., A. Srikiatkhachorn
Involvement Of 5-Ht2a Receptor In Chronic Inflammatory Pain, M. Kaewwongse, Le Grand Sm., A. Srikiatkhachorn
Chulalongkorn Medical Journal
No abstract provided.
Intrarenal Gene Expression Of Monocyte Chemoattractantprotein-1 And Interleukin-6 In Nephrolithiasis, S. Bovornpadungkitti, C. Hunapathed, K. Poonpirome, P. Tosukhowong, C. Predanon, U. Nuanthaisong, S. Ratchanon, A. Wathanavaha, K. Tungsana, C. Boonla
Intrarenal Gene Expression Of Monocyte Chemoattractantprotein-1 And Interleukin-6 In Nephrolithiasis, S. Bovornpadungkitti, C. Hunapathed, K. Poonpirome, P. Tosukhowong, C. Predanon, U. Nuanthaisong, S. Ratchanon, A. Wathanavaha, K. Tungsana, C. Boonla
Chulalongkorn Medical Journal
No abstract provided.
The Role Of Cytokines In Bovine Mastitis, Kittisak Ajariyakhajorn
The Role Of Cytokines In Bovine Mastitis, Kittisak Ajariyakhajorn
The Thai Journal of Veterinary Medicine
Cytokines are protein mediators produced by the immune and nonimmune cells that are involved in the regulation of inflammation and immune responses. The availability of several recombinant bovine cytokines have led to the investigation of the potential of cytokines as prophylactic or therapeutic strategies in the control of bovine mastitis, the most expensive disease affecting the dairy industry. The main goals of cytokine therapy are to enhance the immune response in the mammary gland against pathogenic bacteria, to increase the efficacy of antibiotic treatment, and to enhance the specific immunity of mastitis vaccines. Important cytokines used in mastitis studies are …
The Role Of Leukotrienes In The Pathogenesis Ofsteroid-Sensitive Nephrotic Syndrome, Sevgi Mi̇r, Afig Hüseyi̇nov, Mehmet Kantar, Caner Kabasakal, Alphan Cura, Işıl Çoker
The Role Of Leukotrienes In The Pathogenesis Ofsteroid-Sensitive Nephrotic Syndrome, Sevgi Mi̇r, Afig Hüseyi̇nov, Mehmet Kantar, Caner Kabasakal, Alphan Cura, Işıl Çoker
Turkish Journal of Medical Sciences
Endogenous leukotrienes (LT) levels in plasma and urine samples, and LT levels released from stimulated leukocytes in vitro were examined in children with steroid sensitive nephrotic syndrome (SSNS). Plasma LT concentrations were found to be higher in the SSNS group than in healthy subjects. Subjects with SSNS were also shown to have high levels of urinary cysteinyl-LTs and LTB 4 , while healthy children had only urinary LTE 4 levels. In the second part of the study, peripheral leukocytes of patients and heatlhy children were stimulated by Ca ionophore, A23187. We detected significantly higher levels of LTs in patients with …
โรงพยาบาลจุฬาลงกรณ์ สภากาชาดไทย สถานที่ตั้งคณะแพทย์ศาสตร์แห่งที่ 2 งานชิ้นเอกด้านภูมิทัศน์และสถาปัตยกรรม, Narin Hirunsithikul
โรงพยาบาลจุฬาลงกรณ์ สภากาชาดไทย สถานที่ตั้งคณะแพทย์ศาสตร์แห่งที่ 2 งานชิ้นเอกด้านภูมิทัศน์และสถาปัตยกรรม, Narin Hirunsithikul
Chulalongkorn Medical Journal
No abstract provided.
Histamine And A Possible Unity Of Autonomous Microcirculatory Dilator Responses: Histamine And Autonomous Dilation, Richard W. Schayer
Histamine And A Possible Unity Of Autonomous Microcirculatory Dilator Responses: Histamine And Autonomous Dilation, Richard W. Schayer
MCV/Q, Medical College of Virginia Quarterly
In this paper I will try to show how the proposed intrinsic dilator mechanism may, with due allowance for a variety of modifying factors, underlie the dilator phases of reactive hyperemia, post-exercise hyperemia, hyperemia due to local warmth, autoregulation, vasomotion, inflammation, and shock. These ideas are based on histamine studies (Schayer, 1962, 1963, 1966). However since there is much misunderstanding about histamine, and since the theory can be largely developed without need to identify the dilator, this paper will be presented in two parts. First, interpretation of the above phenomena in terms of intrinsic dilator mechanism will be attempted. Second, …