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The Cardiovascular And Metabolic Adaptations To Iso-Caloric Moderate Intensity And High Intensity Exercise, Summerson Desmond Jan 1999

The Cardiovascular And Metabolic Adaptations To Iso-Caloric Moderate Intensity And High Intensity Exercise, Summerson Desmond

Theses, Dissertations and Capstones

Cardiovascular disease is the leading cause of death in the industrialized nations, and accounts for 1 million deaths in the United States each year (McArdle, Katch & Katch, 1991). One of the major risk factors for cardiovascular disease is physical inactivity, which is a behavioral modified risk factor. Physical inactivity plagues 59% of the people in the United States (ACSM Resource Manual, 1998). Physical inactivity often leads to obesity, diabetes, hypertension and hypercholemia, and places sedentary individuals at more risk for cardiovascular disease (CVD), or coronary heart disease (CHD). The question which remains unclear is the quantity and quality of …


A Cross-Validation Of The Marshall University Step Test On College Males And Females Age 18-24, Mary Robin Hampton Jan 1999

A Cross-Validation Of The Marshall University Step Test On College Males And Females Age 18-24, Mary Robin Hampton

Theses, Dissertations and Capstones

Positive health entails more than the absence of disease; it is a state of physical, mental, and social well-being (Hartung, Krock, Crandall, Bisson, & Myhre, 1993; Payne & Hahn, 1995). Physical fitness, as described by Francis (1987), is the potential for making adequate functional adjustments to increased metabolic demands. Cardiorespiratory fitness (aerobic fitness) is believed to be the single best indicator of physical fitness (Astrand & Rodale, 1985). The standard index of cardiorespiratory fitness is maximum oxygen uptake (VO^^), or the maximum rate at which oxygen can be consumed. VO2max is dependent upon the cardiovascular system’s ability to deliver blood …


Interaction Of Laminin Beta2 With Eps8 And Desmin In Muscle Cells, Luke Xueliang Cui Jan 1999

Interaction Of Laminin Beta2 With Eps8 And Desmin In Muscle Cells, Luke Xueliang Cui

Theses, Dissertations and Capstones

Laminin β2 is localized to the synaptic basal lamina (BL) in muscle and glomerular BL in kidney. To find interacting proteins, a mouse kidney cDNA library was screened with domain I of rat laminin β2 using the yeast two-hybrid system. Fifteen positive clones were found. The DNA sequence of three each of these clones corresponded to the phosphoprotein Eps8 (epidermal growth factor receptor pathway substrate clone 8, which is tyrosine phosphorylated after EGF stimulation) and the intermediate filament (IF) protein keratin. To determine if this interaction occurred in muscle cells, C2 cells transfected with the rat …


Depression In Women With Heart Disease, Kimberly M. Ashcraft Jan 1999

Depression In Women With Heart Disease, Kimberly M. Ashcraft

Theses, Dissertations and Capstones

The purpose of this study was to examine the relationship between anxiety and anger with depression in women with heart disease. A sample of 50 women participating in cardiac rehabilitation programs in Charleston, WV and Huntington, WV was used to evaluate the inter-relationship of suppressed, expressed, state and trait anger, state and trait anxiety and depression. This non-experimental, descriptive designed study was evaluated by using multiple linear regression and regression coefficients analyzed for the anger and anxiety scores and their interaction. Depression was measured by the Beck Depression Inventory II (BDI-II). Anxiety and anger were measured by Spielberger’s State-Trait Anxiety …