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Life Sciences

University of Nebraska at Omaha

Interdisciplinary Informatics Faculty Publications

2018

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Trimethyltin-Induced Cerebellar Damage On Adult Male Wistar Rats. Trimetil Estaño Induce Daño Cerebral En Ratas Machos Adultas Wistar., M. S. Ajao, A. Okesina, Martin C. Nwadiugwu Jan 2018

Trimethyltin-Induced Cerebellar Damage On Adult Male Wistar Rats. Trimetil Estaño Induce Daño Cerebral En Ratas Machos Adultas Wistar., M. S. Ajao, A. Okesina, Martin C. Nwadiugwu

Interdisciplinary Informatics Faculty Publications

Abstract: This research work was done to investigate the acute toxicological effect of trimethyltin chloride on the cerebellum of Wistar rat. Ten adult male Wistar rats were used for the study. The animals were grouped into two: Group A and B, with five adult male Wistar rats in each group. Group A serves as the trimethyltin (TMT) group, while group B serves as the normal saline (NS) group. 3mg/kg of trimethyltin chloride was administered to animals in the TMT group, while 1.0mls of normal saline was administered to the animals in the NS group via intraperitoneal route for 3 …