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The Effects Of Exercise Training On Cardiovascular-Related Circulating Micrornas, Jacob Luther Barber

Theses and Dissertations

PURPOSE: MicroRNAs (miRNAs) are small regulatory RNAs that post transcriptionally modify mRNAs and control gene expression. Circulating miRNAs are significantly altered following a single session of exercise, however the effects of exercise training on the circulating miRNA profile is unclear. Therefore, the purpose of the present study was to determine the effects of endurance exercise training on the abundance of targeted circulating miRNAs and the association of changes in miRNA levels with concomitant changes in cardiometabolic traits, in a subsample of adults from the HERITAGE Family Study.

METHODS: This exploratory analysis examined 20 previously sedentary adults from the HERITAGE Family …

Outsmarting The Brain: Augmenting Motor Training With Non-Invasive Brain Stimulation In Order To Facilitate Plasticity-Dependent, Functional Improvement Within The Motor Cortex, Raymond Joseph Butts

Theses and Dissertations

Brain stimulation techniques capable of optimizing cortical plasticity may provide the key to improved therapeutic techniques and functional outcomes. The primary aim of this dissertation was to examine the potential of motor training (MT) augmented with intermittent theta burst stimulation (iTBS) and anodal transcranial direct current stimulation (a-tDCS). The secondary aim was to investigate whether the training would also be advantageous to older-adults. We hypothesized that right-handed, college-age students exposed to the treatment (n=17) would perform better short-term (directly following MT) and long-term (24 hours and 7 days following MT) on motor-skill retention tests than students receiving sham stimulation (n=14). …