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Total And Regional Bmd Comparison Of Collegiate Male And Female Athletes, Michael G. Robinson 6978741

Williams Honors College, Honors Research Projects

Total and Regional BMD Comparison of Collegiate Male and Female Athletes

Abstract

INTRODUCTION: Physiological and biomechanical demands of different sports have varying effects on the athletes that play them. For example, previous studies have shown that runners and swimmers can have lower bone mineral density (BMD) than athletes in ball sports or inactive controls. PURPOSE: To quantify and compare BMD in athletes to better understand how certain sport specific exercise promotes bone acquisition. METHODS: Fifty one (N=51) NCAA Division I athletes (18-25 yrs) had a whole body DXA scan performed to quantify total body BMD and segmental BMD. Fifteen (n=15) …

Relationships Between Fecal Indicator Bacteria And Environmental Factors At Edgewater Beach, Anna M. King

Williams Honors College, Honors Research Projects

To provide more timely estimates of indicator bacteria concentrations in recreational waters, environmental agencies are using predictive models to supplement conventional bacteria enumeration methods. As a tool to develop predictive models, correlational relationships between variables can be examined, to determine the statistical significance of explanatory variables. Prior research at Lake Erie beaches suggests that environmental conditions such as average wave height, rainfall, turbidity, and water temperature may demonstrate a strong relationship to concentrations of fecal indicator bacteria Escherichia coli and Enterococcus faecalis (enterococci). These relationships were examined at Edgewater Beach in Cleveland, Ohio, using statistical correlation tests on data collected …

Calculating The Rate Of Spread Of Phragmites Australis In Summit County, Oh Using Gis, Aaron W. Baumgardner

Williams Honors College, Honors Research Projects

Phragmites australis subspecies australis is a non-native species that forms dense monocultures and negatively affects wetland ecosystems. In this study, Geographic Information System (GIS) was used to analyze and compare intrinsic rates of growth between Phragmites populations located along highways and those within parks in Summit County, Ohio. No significant difference in expansion rate was seen between the two population types during a 4-year time period, although the average expansion rate was higher in park populations. Obstruction by roads may have prevented highway populations from expanding radially, while 2/3 of park populations were unobstructed in terms of physical barriers to …

Lipid-Protein Interactions Via Fluorescence Quenching In Small Unilamellar Vesicles, Talia Kordahi

Williams Honors College, Honors Research Projects

Studying peptide interactions with model membranes have aided in understanding protein-lipid interactions more clearly. In this report, fluorescent small unilamellar vesicles (SUVs) of a known composition were made. Two peptides, RND1 and MARCKS, were also fluorescently labeled and added to a solution of SUVs. The interactions between these were observed via fluorescence quenching, read out with a spectrofluorimeter. In addition, two environments of buffer were tested: 1X PBS and 0.1X PBS. After obtaining data, it was concluded that MARCKS quenched the SUVs more than RND1. This could be due to the presence of more lysine amino acids in MARCKS, which …

Effects Of Invasion Timing In A One-Dimensional Model Of Competing Species With An Infectious Disease, Eliza Jacops

Williams Honors College, Honors Research Projects

In combining two classes of models, we are able to analyze the dynamics of two species that compete for the same resources while fighting a disease. The native species is the disease host and the invasive species enters their habitat and encounters the disease for the first time. Their natural response is to evolve resistance to the disease, and this can assist in their invasion of the natives' habitat. We find conditions for coexistence of the two species, conditions under which an invasion would succeed and wipe out all native individuals, and conditions under which the invasion fails. We explore …

The Changes In Woodlot Land Cover From 1988 To 2006 Within Private/Farmland In Hancock County, Ohio, Louis C. Birchall

Williams Honors College, Honors Research Projects

The amount of woodlots in Ohio have dramatically decreased since the introduction of settlers into the State. The removal of forest for open space, urban areas, fuel and resources was key to this change. Since the development of the economy to a more service based industry in recent years, woodlots have begun to return in certain areas. This research shows the change in woodlot patterns in Hancock County, Ohio from 1988 to 2006.

The analysis was done by classifying the data into 'woodlot' and 'other land use' by using image segmentation and manual editing processes. Accuracy checks were conducted on …

Effect Of Altered Vegfr2 Expression On Oxidative Stress In A Rodent Model Of Preeclampsia Pathology, Madison Kaser

Williams Honors College, Honors Research Projects

Preeclampsia is a disease that results in pathologies in both the mother and the fetus that lead to oxidative stress. A decrease in vascular endothelial growth factor (VEGF) signaling may be one factor that contributes to this pathology. We hypothesize that by increasing vascular endothelial growth factor receptor 2 (VEGFR2) expression via administration of L-tyrosine phosphate (LTP) nanoparticles, the conditions of both the mother and fetus will be improved. Following treatment with the nanoparticles, we will employ a lucigenin chemiluminescence assay to determine levels of oxidative stress within the placenta. There are three groups that will be compared which are …

Pollinator Sharing Between Mimulus Ringens And Coflowering Plant Species In Northeastern Ohio, Andrew M. Wuellner

Williams Honors College, Honors Research Projects

Competition between plants for pollinators can have serious impacts on plant reproduction; these impacts depend on many factors, such as plant abundance, plant diversity, floral abundance, pollinator abundance, and pollinator preference. The way pollinators move among and between coflowering species can tell us more about how these factors affect competition. In this study, we examine the movement patterns of flower visitors to Mimulus ringens and coflowering species in Northeastern Ohio through several types of observations. In addition, we measured the density and diversity of floral units with 20-30 meter transects across each study site. There were six total study sites, …

Stress And Exercise In Undergraduate Health Professions Students, Kristin R. Weismantel, Meghan G. Brickner, Leah N. Rosler

Williams Honors College, Honors Research Projects

Background: Stress is prevalent among undergraduate students, especially students in health professions majors. Exercise as a health promoting behavior decreases stress. At the same time, increased stress may decrease exercise. This study described exercise and stress among undergraduate health professions students. More specifically this study described the intensity and duration of each exercise and the frequency of exercise during a typical week of the semester for students in health professions majors.

Theoretical framework: Pender’s Health Promotion Model guided this study.

Design: Cross-sectional, descriptive survey.

Methods: A convenience sample of 437 undergraduate students in a college of health professions (N =2,700) …

Rep As A Predictor Of Weight Categories Determined By Anthropometric Measurements, Nicholas Mendola

Williams Honors College, Honors Research Projects

Obesity has become one of the leading public health issues in the world today. An aspect of this issue that must be addressed in order for it to not persist as a problem in the future is the issue of childhood obesity. One of the most common screening methods to determine if a child is classified as overweight or obese is to utilize anthropometric measurements like body mass index, and waist-to-height ratios. Past studies have shown that children who are categorized as overweight or obese can struggle with physical activity and typically have lower fitness levels as their anthropometric measurements …

Factors Affecting Injury History And Their Overall Impact On Athletic Performance In Distance Runners, Trevor Norris

Williams Honors College, Honors Research Projects

Distance running is a very precise mechanism of many intricate movements and abilities of the body. The amount of miles that a distance runner must run puts a lot of very intense stresses on one’s body. These stresses often appear at the bone level and lead to many injuries such as stress reactions and stress fractures but also may play important roles in tissue damages such as strains and pulls. In this study, we used division one college distance runners and examined many intricacies between their level of fitness and overall composition. These include looking at imbalances, dominant traits, and …

Investigation Of Dna Interaction With Bis-Cationic Imidazolium Salts, Kyle Daily 6440928

Williams Honors College, Honors Research Projects

Imidazolium salt compounds have shown promise in vitro against non-small cell lung cancer (NSCLC) lines, but the exact mechanism of activity these compounds is still unknown. Due to their planar aromatic structure, we hypothesized that our bis-cation imidazolium salt series could act through DNA intercalation similar to known intercalators ethidium bromide, acridine orange, and echinomycin. Here, we tested bis-cation imidazolium salts with linkers of 2, 4, 10, and 12 carbons for DNA intercalation via viscosity and fluorescent intercalator displacement (FID) assays. Despite some solubility issues that may have decreased results, we found that our butyl and dodecyl linked compounds had …

Untargeted Metabolomic Profiling Of Rolipram-Stimulated Immune Cells, Sterling Shriber Ii

Williams Honors College, Honors Research Projects

Inflammation is a significant component of neurological diseases such as multiple sclerosis (MS). One potential anti-inflammatory agent, rolipram, was tested for efficacy in MS; however, despite showing promise in early trials, the drug has been largely sidelined due to side effects. However, it is still of interest to elucidate the anti-inflammatory mechanisms of rolipram in order to identify more targeted inhibitors of inflammatory signaling. In order to achieve this end, we have utilized liquid chromatography-mass spectrometry-based metabolomics to determine metabolic pathways that are altered by rolipram treatment in human THP-1 monocytic cells and primary mouse microglial cultures. Amino acids and …

Identification And Quantification Of Zooplankton In Ne Ohio Drinking Water Reservoirs, Michael Vigorito

Williams Honors College, Honors Research Projects

Cyanobacteria, or blue-green algae, are present in most freshwater ecosystems and are usually harmless. When these algae swell in numbers, they release harmful toxins that can be detrimental to animal and human health, and can destroy ecosystems. For this reason, many scientists and engineers have studied these harmful algal blooms in an attempt to predict, prevent, or control them to keep people and ecosystems safe. One of the variables in this investigation is the presence and quantity of zooplankton. These animals could play an important role in the prevalence of cyanobacteria, but more information is needed to determine what that …

The Role Of Tgfβ1 And Ep Receptors In The Differentiation Of Normal And Diseased Lung Fibroblasts, Madison A. Hexter

Williams Honors College, Honors Research Projects

Fibroblasts, and their differentiation into myofibroblasts, are important in the pathology of several lung diseases including asthma and idiopathic pulmonary fibrosis (IPF). The differentiation process is dependent on several factors, such as soluble factors like transforming growth factor beta 1 (TGFβ1) and mechanical signals such as matrix stiffness. Additionally, the soluble arachidonic acid metabolite Prostaglandin E₂ (PGE₂) prevents TGFβ1 induced differentiation of fibroblasts to myofibroblasts, but the molecular mechanism is not completely understood¹⁵. Transient Receptor Potential Vanilloid 4 (TRPV4), a mechanosensitive ion channel, has previously been implicated in the differentiation of cardiac fibroblasts^12,13. …

Case Study: Observing The Effects Of Length Of Exposure To Mnv On Mice Colonies, Beau Brown

Williams Honors College, Honors Research Projects

Four groups of experimental mice are studied in this experiment following intentional exposure to murine norovirus (MNV). Two groups are exposed to the virus at different points in their lives, and the other two are not infected and studied alongside the other groups as controls.

Past research has indicated that B and T immune cells are not essential to MNV resistance. Additionally, antibody production against MNV has shown to be slow as infection progresses. Thus, the expected results from the experiment are that the mice with longer infections of MNV will have larger quantities of IgG than those more recently …

Assessing The Expression Of Astrocytic Markers In Retinal Ganglion Cell Projection Of Lcr/Hcr Rats, Isabella K. Bartholomew, Samuel Crish, James Holda, Jordan Renna, Gina Wilson

Williams Honors College, Honors Research Projects

Metabolic Syndrome is a human condition that presents with various metabolic issues such as abnormal distribution of body fat, high blood pressure, and a prothrombotic state, among other problems (Alberti,et al, 2005). This syndrome is a risk factor for visual disorders, such as glaucoma, and is often associated with increased levels of neuroinflammation. Currently, the animal model used to replicate this syndrome is The Low Capacity Runner and High Capacity Runner Rat Model. These rats have been bred based on their running capacities for 30+ generations to have drastic metabolic differences. We assessed key areas of the retinal ganglion cell …