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Examining Effects Of Arousal And Valence Across The Adult Lifespan In An Emotional Stroop Task, Samantha E. Tuft
Examining Effects Of Arousal And Valence Across The Adult Lifespan In An Emotional Stroop Task, Samantha E. Tuft
ETD Archive
As age increases, there is evidence that people tend to pay less attention to negative information, pay more attention to positive information, or both. There are many theoretical accounts that attempt to explain this positivity bias. In the current study, I examined positivity effects across the adult lifespan by evaluating competing predictions of two theories: Socioemotional Selectivity Theory, which is based in motivation, and Dynamic Integration Theory, which is based in capacity. Computer mouse tracking was used to examine effects across levels of Valence (negative, neutral, and positive) and Arousal (low, medium, and high) in an emotional Stroop task. Participants …
Age And Sex-Specific Effect Of Caloric Restriction On Circadian Clock And Longevity-Associated Gene Expression, Arten Andreyevich Astafev
Age And Sex-Specific Effect Of Caloric Restriction On Circadian Clock And Longevity-Associated Gene Expression, Arten Andreyevich Astafev
ETD Archive
The rhythms in the expression of circadian clock genes are affected by calorie restriction (CR), a dietary paradigm known to increase lifespan. In our current study, we show that circadian rhythms are influenced by sex and the effects of CR are different between males and females. In particular, we found a group of clock genes which showed a sex-dependent difference in expression, as well as in response to CR (Rev-Erb α, Ror γ and both Cryptochromes: Cry1 and Cry2 genes). Two clock genes showed no difference in expression but their response to CR showed sexual dimorphism (Ror α and Rev-Erb …
Circadian Regulation Of Mtor Signaling Via Bmal1 Dependent Mechanism, Rohini Vishal Khapre
Circadian Regulation Of Mtor Signaling Via Bmal1 Dependent Mechanism, Rohini Vishal Khapre
ETD Archive
Understanding mechanisms of aging is important for the treatment and prevention of age-associated pathologies. However, these mechanisms are not well understood. Recently we have demonstrated that the circadian clock (an internal time keeping system) regulates longevity in mammals, but the molecular mechanisms are not known. The aim of our current study is to investigate a possible interconnection between the circadian clock and mTORC1 (mammalian target of Rapamycin) signaling pathway. mTORC1 pathway is a nutrient response pathway involved in many cellular processes many recent studies indicate a role of mTORC1 pathway in aging. Here we demonstrate that circadian system regulates mTORC1 …