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A Case Report Of Florid Liver Failure Responding Favorably To Targeted Therapy With Cetuximab And Encorafenib Following Treatment With Irinotecan And Bevacizumab In Metastatic Colorectal Cancer, Maryam Fallahi, Omar Garcia, Joseph Kim Jan 2024

A Case Report Of Florid Liver Failure Responding Favorably To Targeted Therapy With Cetuximab And Encorafenib Following Treatment With Irinotecan And Bevacizumab In Metastatic Colorectal Cancer, Maryam Fallahi, Omar Garcia, Joseph Kim

North Texas GME Research Forum 2024

Introduction: Colorectal cancer, commonly known as colon cancer, is a globally widespread and formidable malignancy originating from the epithelial cells lining the colon and rectum. This disease, demonstrating geographical and demographic variations, particularly prevails in Western countries. The progression of colon cancer typically spans years, initiated by the development of adenomatous polyps, presenting an opportune timeframe for early detection and intervention. The substantial morbidity and mortality rates associated with colon cancer underscore its significance as a public health concern. Various risk factors, such as age, family history, genetic predisposition, inflammatory bowel diseases, and lifestyle factors like diet and physical activity, …


Comparing The Ppv Of At-Home Screening Tests With Chronic Anticoagulant And/Or Antiplatelet Therapies, Bradley Gustafson, Nasima Mehraban, Amjad Awan, Michele Mccarroll Jan 2024

Comparing The Ppv Of At-Home Screening Tests With Chronic Anticoagulant And/Or Antiplatelet Therapies, Bradley Gustafson, Nasima Mehraban, Amjad Awan, Michele Mccarroll

North Texas GME Research Forum 2024

BACKGROUND: With the rising incidence and mortality of colorectal cancer (CRC), early diagnosis and treatment is imperative. At-home CRC screening kits are a non-invasive Federal Drug Association (FDA) approved designed to detects either hemoglobin or DNA markers associated for CRC and high-grade polyps. Therefore, therapies that have a propensity to increase rates of gastrointestinal bleeding could theoretically lead to higher false positive rates. The goal of this study was to determine the positive predictive value of at-home screening tests when applied to patients on therapies such as antiplatelet, anticoagulant, non-steroidal anti-inflammatory (NSAID), or a combination of the three. METHODS: The …


Multidisciplinary Management For Large And Difficult Choledocholithiasis: The Role Of Choledochotomy, Jilpa Shah, Balu Chandra Jan 2024

Multidisciplinary Management For Large And Difficult Choledocholithiasis: The Role Of Choledochotomy, Jilpa Shah, Balu Chandra

North Texas GME Research Forum 2024

Extracranial carotid artery aneurysm is a rare sequela of atherosclerosis, trauma, and conditions of chronic inflammation. Standard treatments include antiplatelet medications, open resection, or endovascular stenting. Transcarotid artery revascularization (TCAR) has become a well-recognized alternative treatment in the past few decades. This case study documents the first reported case of Horner’s syndrome post-TCAR for an internal carotid artery (ICA) aneurysm. A 68 year-old male with intermittent double vision was referred to vascular surgery clinic with brain CT angiography showing a 9mm saccular aneurysm with dissection flap of the right cervical ICA. Prior attempts by neuro-interventional radiology were unsuccessful due to …


Case Report: Streptococcus Gallolyticus Prosthetic Joint Infection, Jeffrey Dickerson, Liza Salloum, Amaan Sheikh, Madhukanth Reddy, Bryan Youree Jan 2024

Case Report: Streptococcus Gallolyticus Prosthetic Joint Infection, Jeffrey Dickerson, Liza Salloum, Amaan Sheikh, Madhukanth Reddy, Bryan Youree

North Texas GME Research Forum 2024

Streptococcus gallolyticus, part of the Streptococcus bovis/Streptococcus equinus complex (SBSEC) formerly known as Group D streptococi, is strongly associated with colorectal cancer and infective endocarditis. Its appearance in septic arthritis is rare, and its role in septic arthritis has not been as thoroughly investigated. We present the case of a 69 year old male with a history of atrial fibrillation and hypertension who was admitted to our hospital after undergoing a right knee replacement in 2023 with a chief complaint of right knee pain, fever, and chills. Arthrocentesis and blood cultures were performed, and the patient was started on …


Association Of Glucagon-Like Peptide-1 Receptor Agonist Treatment With Perioperative And Postoperative Complications In Patients Undergoing Elective Bariatric Surgery, Justin Sanchez, Enith Espinosa, Sean Sojdie, Michael Green, Lauren Wonderly Jan 2024

Association Of Glucagon-Like Peptide-1 Receptor Agonist Treatment With Perioperative And Postoperative Complications In Patients Undergoing Elective Bariatric Surgery, Justin Sanchez, Enith Espinosa, Sean Sojdie, Michael Green, Lauren Wonderly

North Texas GME Research Forum 2024

Glucagon-like peptide receptor agonists (GLP-1 RA) are FDA-approved medications for the treatment of type 2 diabetes mellitus, and obesity, and are also beneficial in cardiovascular risk reduction. However, due to known GLP-1 RA adverse effects, notably delayed gastric emptying, the ASA has implemented GLP-1RA guidelines aiming to minimize potential complications related to GLP-1 RA use in patients undergoing procedures requiring general anesthesia. With the ever-increasing number of patients being prescribed GLP-1 RAs, more research needs to be conducted to investigate their potential impact in other areas of healthcare. This retrospective study aims to compare surgical outcomes before and following the …