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Articles 1 - 9 of 9
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Tnf-Alpha Inhibition Of Adiponectin Expression By Targeting Ppar-Gamma And C/Ebp In Adipocytes, Yanning Wang
Tnf-Alpha Inhibition Of Adiponectin Expression By Targeting Ppar-Gamma And C/Ebp In Adipocytes, Yanning Wang
LSU Master's Theses
Chronic inflammation is involved in the adipose tissue dysfunction through regulation of endocrine and storage function of adipocytes. As a representative proinflammatory cytokine, TNF-α was reported to inhibit expression of adiponectin. However, the mechanism of inhibition remains to be identified. Here, we provide experimental evidence that TNF-α inhibits adiponectin at both transcriptional and posttranscriptional levels. In three animal models (aP2-P65, ob/ob and high fat diets-fed mice), an increase in TNF-α expression was associated with a decrease in adiponectin expression. In 3T3-L1 adipocytes, TNF-α inhibition of adiponectin was observed at mRNA and protein levels. Luciferase reporter assay and mRNA stability tests …
Regulation Of Adipose Tissue Metabolism By Nfkb P65 In Transgenic Mice, Tianyi Tang
Regulation Of Adipose Tissue Metabolism By Nfkb P65 In Transgenic Mice, Tianyi Tang
LSU Master's Theses
Inflammation has been widely reported to regulate adipocyte functions in adipose tissue. Our early study suggests that NFkB signaling pathway is activated by inflammation and involved in inhibition of insulin sensitivity in adipocytes. NFkB was found to inhibit PPARg function through several possible mechanisms in 3T3-L1 adipocytes. To test this possibility in vivo, we increased the NFkB activity in adipocytes in transgenic mice by expression of NFkB p65 subunit under the aP2 gene promoter. The phenotype study shows that the food intake, physical activity and development are similar in the two groups. The reproductivity was not different in the two …
The Role Of Glucagon-Like Peptide-1 On Food Intake, Glucokinase Expression And Fatty Acid Metabolism, Hanjie Zhang
The Role Of Glucagon-Like Peptide-1 On Food Intake, Glucokinase Expression And Fatty Acid Metabolism, Hanjie Zhang
LSU Master's Theses
The increase in blood levels of GLP-1 with dietary resistant starch is thought to be associated with the activities of hypothalamic NPY/AgRP neurons and the gene expression of glucokinase in the ARC of the hypothalamus. Exendin-4 has been shown to be associated with fatty acid synthesis and oxidation. In this project, it was proposed that 1) food intake will be decreased in GLP-1R KO mice, the glucokinase (GK) mRNA expression in the liver and in the hypothalamus, the hypothalamic NPY mRNA expression will be up-regulated by exendin-4 treatment; and 2) exendin-4 will decrease fatty acid synthesis and increase fatty acid …
The Perception Of The Louisiana Food Stamp Nutrition Education Program's Ability To Improve Diet And Other Lifestyle Measures Of Participants, Melly Suyapa Perez Garay
The Perception Of The Louisiana Food Stamp Nutrition Education Program's Ability To Improve Diet And Other Lifestyle Measures Of Participants, Melly Suyapa Perez Garay
LSU Master's Theses
The purpose of this study was to assess the perception of Louisiana Food Stamp Nutrition Education Program (FSNEP) participants’ diet and other lifestyle measures and their consistency with the current Dietary Guidelines for Americans and MyPyramid compared to eligible non-participants in Louisiana. The study sample included FSNEP adult participants (Group 1; n=30) and adult non-FSNEP participants (Group 2; n=26) from 5 parishes in Louisiana. Nine focus group discussions (FGD) were conducted with Group 1 (n=5) and Group 2 (n=4) participants. The FGD assessed perceptions and practice in the last six months of: (a) increasing eating fruit and vegetables, whole grains, …
Relationship Of Maternal Serum Fatty Acids And Body Mass Index, Emily Fontenot Gilbert
Relationship Of Maternal Serum Fatty Acids And Body Mass Index, Emily Fontenot Gilbert
LSU Master's Theses
Maternal supply of nutrients is critical for the developing fetus during all stages of gestation. The altered lipid metabolism that is often seen in pregnancies complicated by obesity and insulin resistance may negatively impact maternal supply to the fetus. More women are entering pregnancy overweight or obese and recently body mass index (BMI) has been found to be a positive predictor for decreased maternal plasma phospholipid concentrations of the long-chain polyunsaturated fatty acids (LCPUFA) docosahexanoic acid (DHA) and arachidonic acid (ARA). These nutrients play important roles in early development and their availability is critical to fetal growth and development. The …
Religiosity And Chinese Immigrants' Marriage, Yaxin Lu
Religiosity And Chinese Immigrants' Marriage, Yaxin Lu
LSU Master's Theses
The existing literature on religion and family indicates that religious beliefs and practices are correlated with various aspects of marriage and family life. Chinese immigrants are an important part of the U.S. population. However, very little is known about the relationship between religion and marriage for Chinese immigrants. The purpose of the study is to examine the relationship between Christianity and marriage in Chinese immigrant families based on in-depth qualitative interviews. Sixteen highly religious Chinese Christian couples were interviewed to examine how religious faith influenced their perceptions of marriage and family life. Most of the participants in this study held …
Infant Communicative Behaviors And Maternal Responsiveness, Chinwe Laura Onwujuba
Infant Communicative Behaviors And Maternal Responsiveness, Chinwe Laura Onwujuba
LSU Master's Theses
This study is an examination of infant communication and maternal responsivity in order to determine the impact of training on mother-infant communicative interaction. A sample of three mothers and their infants were observed during 10 minute free play sessions before and after a training intervention. The focus of the training was the principles of parenting contained in the Right-from-Birth: A Parenting Series (Grace & Lindsey, 2003) training. A multiple baseline design was used to measure maternal responsiveness to infant communication. Positive and negative maternal responses, as well as the rate of infant communication were also measured. Results showed an increase …
The Effect Of Interactive Homework On Dibels Performance, Shelley M. Scott
The Effect Of Interactive Homework On Dibels Performance, Shelley M. Scott
LSU Master's Theses
Homework is a common practice in most kindergarten classrooms. There are varying opinions on the purpose of homework, the frequency in which homework should be given, the duration of time kindergarten-aged students should spend on homework, and how the use of homework impacts student performance. The DIBELS (Good & Kamanski, 2003) is an assessment tool that measures student performance on early literacy skills and identifies students who are at-risk for failure to read. The proposed study will incorporate recommendations for creating developmentally appropriate homework that addresses skill deficiencies identified by the DIBELS to determine the impact of homework on DIBELS …
Polyunsaturated Fatty Acid Content Of Breast Milk From Women With And Without Gestational Diabetes Mellitus, Julissa Marisel Salguero
Polyunsaturated Fatty Acid Content Of Breast Milk From Women With And Without Gestational Diabetes Mellitus, Julissa Marisel Salguero
LSU Master's Theses
Reduced insulin sensitivity and abnormal nutrient metabolism in gestational diabetes mellitus (GDM) may compromise polyunsaturated fatty acid (PUFA) content of breast milk. The purpose of the present study was to evaluate and compare PUFA milk composition of women with and without GDM. Breast milk collections were performed in GDM (n=6) and controls (n=12) at weeks 2, 6, 10 and 12 postpartum using a hospital grade breast pump. Estimated dietary intake of PUFA and use of prenatal supplements containing DHA (PS/DHA) was determined by 24-hour dietary recalls conducted after each milk collection. Based on these preliminary data, milk docosahexaenoic acid (DHA; …